SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1nf6'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RNR_A_DAHA208_1
(RIBONUCLEOTIDE
REDUCTASE R1 PROTEIN)		 1nf6 BACTERIOFERRITIN
(Desulfovibrio
desulfuricans) 		5 / 11 GLU A  56
HIS A  59
GLU A  99
ILE A 128
GLU A 132
 FE  A 200 (-2.2A)
None
FE  A 200 (-2.4A)
None
FE  A 200 (-2.4A)
 0.75A 1rnrA-1nf6A:
9.9		 1rnrA-1nf6A:
18.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RNR_A_DAHA208_1
(RIBONUCLEOTIDE
REDUCTASE R1 PROTEIN)		 1nf6 BACTERIOFERRITIN
(Desulfovibrio
desulfuricans) 		5 / 11 GLU A 132
HIS A 135
GLU A  23
ILE A  52
GLU A  56
 FE  A 200 (-2.4A)
FE  A 200 (-3.2A)
None
None
FE  A 200 (-2.2A)
 0.86A 1rnrA-1nf6A:
9.9		 1rnrA-1nf6A:
18.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RNR_A_DAHA208_1
(RIBONUCLEOTIDE
REDUCTASE R1 PROTEIN)		 1nf6 BACTERIOFERRITIN
(Desulfovibrio
desulfuricans) 		5 / 11 HIS A  59
GLU A  99
SER A 107
ILE A 128
GLU A 132
 None
FE  A 200 (-2.4A)
None
None
FE  A 200 (-2.4A)
 1.45A 1rnrA-1nf6A:
9.9		 1rnrA-1nf6A:
18.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RNR_B_DAHB208_1
(RIBONUCLEOTIDE
REDUCTASE R1 PROTEIN)		 1nf6 BACTERIOFERRITIN
(Desulfovibrio
desulfuricans) 		5 / 12 GLU A  56
HIS A  59
GLU A  99
ILE A 128
GLU A 132
 FE  A 200 (-2.2A)
None
FE  A 200 (-2.4A)
None
FE  A 200 (-2.4A)
 0.75A 1rnrB-1nf6A:
10.1		 1rnrB-1nf6A:
18.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RNR_B_DAHB208_1
(RIBONUCLEOTIDE
REDUCTASE R1 PROTEIN)		 1nf6 BACTERIOFERRITIN
(Desulfovibrio
desulfuricans) 		6 / 12 GLU A 132
HIS A 135
TYR A 139
GLU A  23
ILE A  52
GLU A  56
 FE  A 200 (-2.4A)
FE  A 200 (-3.2A)
None
None
None
FE  A 200 (-2.2A)
 0.88A 1rnrB-1nf6A:
10.1		 1rnrB-1nf6A:
18.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HA6_A_SCKA902_1
(ACETYLCHOLINESTERASE)		 1nf6 BACTERIOFERRITIN
(Desulfovibrio
desulfuricans) 		5 / 10 GLU A  99
ASP A  55
THR A 102
GLU A  23
TYR A 106
 FE  A 200 (-2.4A)
None
None
None
None
 1.43A 2ha6A-1nf6A:
undetectable		 2ha6A-1nf6A:
15.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HA6_B_SCKB952_1
(ACETYLCHOLINESTERASE)		 1nf6 BACTERIOFERRITIN
(Desulfovibrio
desulfuricans) 		5 / 10 GLU A  99
ASP A  55
THR A 102
GLU A  23
TYR A 106
 FE  A 200 (-2.4A)
None
None
None
None
 1.44A 2ha6B-1nf6A:
undetectable		 2ha6B-1nf6A:
15.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L3G_F_ACTF401_0
(METHYLAMINE
DEHYDROGENASE HEAVY
CHAIN)		 1nf6 BACTERIOFERRITIN
(Desulfovibrio
desulfuricans) 		3 / 3 ARG A  20
LEU A  24
GLU A  23
 FEC  A1005 (-2.7A)
None
None
 0.72A 4l3gF-1nf6A:
undetectable		 4l3gF-1nf6A:
18.11