SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1nf9'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MX1_E_THAE5_1
(LIVER
CARBOXYLESTERASE I)		 1nf9 PHENAZINE
BIOSYNTHESIS PROTEIN
PHZD
(Pseudomonas
aeruginosa) 		5 / 12 VAL A 205
VAL A  36
LEU A  34
LEU A 111
MET A  39
 None
 1.44A 1mx1E-1nf9A:
undetectable		 1mx1E-1nf9A:
18.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PBC_A_BHAA396_0
(P-HYDROXYBENZOATE
HYDROXYLASE)		 1nf9 PHENAZINE
BIOSYNTHESIS PROTEIN
PHZD
(Pseudomonas
aeruginosa) 		5 / 10 GLY A 149
LEU A  12
TYR A  10
LEU A  51
ALA A 152
 None
 1.20A 1pbcA-1nf9A:
undetectable		 1pbcA-1nf9A:
22.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJW_G_SVRG506_3
(PHOSPHOLIPASE A2)		 1nf9 PHENAZINE
BIOSYNTHESIS PROTEIN
PHZD
(Pseudomonas
aeruginosa) 		3 / 3 PRO A  79
PHE A 129
LYS A 122
 None
 0.93A 3bjwG-1nf9A:
undetectable		 3bjwG-1nf9A:
16.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ELZ_C_CHDC150_0
(ILEAL BILE
ACID-BINDING PROTEIN)		 1nf9 PHENAZINE
BIOSYNTHESIS PROTEIN
PHZD
(Pseudomonas
aeruginosa) 		5 / 12 THR A 202
VAL A 205
LEU A 157
ILE A 177
THR A 160
 None
 1.18A 3elzC-1nf9A:
undetectable		 3elzC-1nf9A:
17.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3R2J_C_NIOC311_1
(ALPHA/BETA-HYDROLASE
-LIKE PROTEIN)		 1nf9 PHENAZINE
BIOSYNTHESIS PROTEIN
PHZD
(Pseudomonas
aeruginosa) 		5 / 12 ASP A  38
PHE A  43
TRP A  94
LYS A 122
TYR A 125
 None
None
FMT  A 210 ( 4.4A)
None
None
 0.84A 3r2jC-1nf9A:
20.2		 3r2jC-1nf9A:
22.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KPC_A_SAMA401_0
(PAVINE
N-METHYLTRANSFERASE)		 1nf9 PHENAZINE
BIOSYNTHESIS PROTEIN
PHZD
(Pseudomonas
aeruginosa) 		6 / 12 GLY A 149
LEU A  62
VAL A 173
ALA A 174
LEU A 172
ALA A 188
 None
None
None
None
None
BOG  A 250 (-4.6A)
 1.25A 5kpcA-1nf9A:
undetectable		 5kpcA-1nf9A:
17.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X7Z_A_BHAA201_0
(UNCHARACTERIZED
HTH-TYPE
TRANSCRIPTIONAL
REGULATOR RV2887)		 1nf9 PHENAZINE
BIOSYNTHESIS PROTEIN
PHZD
(Pseudomonas
aeruginosa) 		4 / 6 LEU A  62
VAL A 205
LEU A  27
VAL A 200
 None
 0.97A 5x7zA-1nf9A:
undetectable		 5x7zA-1nf9A:
23.70