SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1nfd'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E7A_B_PFLB4002_1
(SERUM ALBUMIN)		 1nfd H57 FAB
(Mus
musculus) 		4 / 6 LEU E 104
VAL E  19
VAL E  15
GLN E  79
 None
 1.09A 1e7aB-1nfdE:
undetectable		 1e7aB-1nfdE:
16.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FDU_B_ESTB354_1
(17-BETA-HYDROXYSTERO
ID DEHYDROGENASE)		 1nfd H57 FAB
(Mus
musculus) 		4 / 8 SER E 176
LEU F 187
TYR F 147
VAL F 152
 None
 1.09A 1fduB-1nfdE:
undetectable		 1fduB-1nfdE:
23.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HWI_B_115B1_2
(HMG-COA REDUCTASE)		 1nfd H57 FAB
N15 ALPHA-BETA
T-CELL RECEPTOR
(Mus
musculus) 		4 / 8 VAL E  97
SER E  91
ASN E  95
LYS B 224
 None
 1.11A 1hwiB-1nfdE:
0.0		 1hwiB-1nfdE:
17.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HWI_C_115C4_1
(HMG-COA REDUCTASE)		 1nfd H57 FAB
N15 ALPHA-BETA
T-CELL RECEPTOR
(Mus
musculus) 		4 / 7 VAL E  97
SER E  91
ASN E  95
LYS B 224
 None
 1.08A 1hwiC-1nfdE:
undetectable		 1hwiC-1nfdE:
17.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HWI_D_115D3_2
(HMG-COA REDUCTASE)		 1nfd H57 FAB
N15 ALPHA-BETA
T-CELL RECEPTOR
(Mus
musculus) 		4 / 7 VAL E  97
SER E  91
ASN E  95
LYS B 224
 None
 1.08A 1hwiD-1nfdE:
0.0		 1hwiD-1nfdE:
17.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HWK_A_117A2_1
(HMG-COA REDUCTASE)		 1nfd H57 FAB
N15 ALPHA-BETA
T-CELL RECEPTOR
(Mus
musculus) 		4 / 8 VAL E  97
SER E  91
ASN E  95
LYS B 224
 None
 1.12A 1hwkA-1nfdE:
undetectable		 1hwkA-1nfdE:
17.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HWK_C_117C4_1
(HMG-COA REDUCTASE)		 1nfd H57 FAB
N15 ALPHA-BETA
T-CELL RECEPTOR
(Mus
musculus) 		4 / 8 VAL E  97
SER E  91
ASN E  95
LYS B 224
 None
 1.13A 1hwkC-1nfdE:
undetectable		 1hwkC-1nfdE:
17.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HWK_D_117D3_2
(HMG-COA REDUCTASE)		 1nfd H57 FAB
N15 ALPHA-BETA
T-CELL RECEPTOR
(Mus
musculus) 		4 / 8 VAL E  97
SER E  91
ASN E  95
LYS B 224
 None
 1.12A 1hwkD-1nfdE:
undetectable		 1hwkD-1nfdE:
17.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1IG3_A_VIBA502_1
(THIAMIN
PYROPHOSPHOKINASE)		 1nfd N15 ALPHA-BETA
T-CELL RECEPTOR
(Mus
musculus) 		4 / 8 TRP B  98
SER B  95
SER B  30
ASN B  31
 None
 0.99A 1ig3A-1nfdB:
undetectable
1ig3B-1nfdB:
0.0		 1ig3A-1nfdB:
20.29
1ig3B-1nfdB:
20.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1IG3_B_VIBB501_1
(THIAMIN
PYROPHOSPHOKINASE)		 1nfd N15 ALPHA-BETA
T-CELL RECEPTOR
(Mus
musculus) 		4 / 7 TRP B  98
SER B  95
SER B  30
ASN B  31
 None
 1.00A 1ig3A-1nfdB:
undetectable
1ig3B-1nfdB:
undetectable		 1ig3A-1nfdB:
20.29
1ig3B-1nfdB:
20.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q23_J_FUAJ711_1
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 1nfd H57 FAB
(Mus
musculus) 		5 / 11 THR E 162
SER E 176
TYR E 178
PHE E 118
VAL F 154
 None
 1.45A 1q23J-1nfdE:
0.0		 1q23J-1nfdE:
20.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UHO_A_VDNA1000_1
(CGMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE)		 1nfd H57 FAB
N15 ALPHA-BETA
T-CELL RECEPTOR
(Mus
musculus) 		5 / 10 TYR E  49
HIS F 100
ALA E  33
PHE E  32
GLY B  16
 None
 1.15A 1uhoA-1nfdE:
undetectable		 1uhoA-1nfdE:
20.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZZR_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 1nfd H57 FAB
(Mus
musculus) 		4 / 7 VAL E 106
ARG E  61
VAL E  19
GLU E  83
 None
 1.04A 1zzrA-1nfdE:
0.0
1zzrB-1nfdE:
0.0		 1zzrA-1nfdE:
18.67
1zzrB-1nfdE:
18.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZZR_B_H4BB761_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 1nfd H57 FAB
(Mus
musculus) 		4 / 7 GLU E  83
VAL E 106
ARG E  61
VAL E  19
 None
 1.07A 1zzrA-1nfdE:
0.0
1zzrB-1nfdE:
0.0		 1zzrA-1nfdE:
18.67
1zzrB-1nfdE:
18.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZZU_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 1nfd H57 FAB
(Mus
musculus) 		4 / 7 VAL E 106
ARG E  61
VAL E  19
GLU E  83
 None
 1.05A 1zzuA-1nfdE:
0.0
1zzuB-1nfdE:
0.0		 1zzuA-1nfdE:
18.67
1zzuB-1nfdE:
18.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZZU_B_H4BB761_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 1nfd H57 FAB
(Mus
musculus) 		4 / 7 GLU E  83
VAL E 106
ARG E  61
VAL E  19
 None
 1.05A 1zzuA-1nfdE:
0.0
1zzuB-1nfdE:
0.0		 1zzuA-1nfdE:
18.67
1zzuB-1nfdE:
18.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2D55_C_DVAC2_0
(ACTINOMYCIN D)		 1nfd N15 ALPHA-BETA
T-CELL RECEPTOR
(Mus
musculus) 		3 / 3 THR B 123
PRO B 125
PRO B 232
 None
 0.85A 2d55C-1nfdB:
undetectable		 2d55C-1nfdB:
7.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FT9_A_CHDA130_0
(FATTY ACID-BINDING
PROTEIN 2, LIVER)		 1nfd H57 FAB
(Mus
musculus) 		5 / 12 VAL F 121
ASN F 162
ILE F 205
ILE F 225
VAL F 193
 None
 1.16A 2ft9A-1nfdF:
0.4		 2ft9A-1nfdF:
18.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JN3_A_JN3A130_2
(FATTY ACID-BINDING
PROTEIN, LIVER)		 1nfd N15 ALPHA-BETA
T-CELL RECEPTOR
(Mus
musculus) 		4 / 7 LEU B  21
PRO B  61
GLU B  83
ARG B  64
 None
 1.07A 2jn3A-1nfdB:
undetectable		 2jn3A-1nfdB:
20.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2M2P_B_DHIB24_0
(INSULIN B CHAIN)		 1nfd H57 FAB
(Mus
musculus) 		3 / 3 TYR F 185
GLY F 146
PHE F 148
 None
 0.62A 2m2pB-1nfdF:
undetectable		 2m2pB-1nfdF:
8.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QEB_A_HSMA145_1
(D7R4 PROTEIN)		 1nfd N15 ALPHA-BETA
T-CELL RECEPTOR
(Mus
musculus) 		4 / 7 ILE A 181
ARG B 195
PHE A 146
ASP A 145
 None
 0.99A 2qebA-1nfdA:
undetectable		 2qebA-1nfdA:
18.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QEB_B_HSMB145_1
(D7R4 PROTEIN)		 1nfd N15 ALPHA-BETA
T-CELL RECEPTOR
(Mus
musculus) 		4 / 7 ILE A 181
ARG B 195
PHE A 146
ASP A 145
 None
 1.01A 2qebB-1nfdA:
undetectable		 2qebB-1nfdA:
18.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VAX_K_CSCK1385_1
(ACETYL-COA--DEACETYL
CEPHALOSPORIN C
ACETYLTRANSFERASE)		 1nfd N15 ALPHA-BETA
T-CELL RECEPTOR
(Mus
musculus) 		5 / 12 LEU B 114
THR B 115
LYS B  41
ARG A 111
GLN B 177
 None
 1.48A 2vaxK-1nfdB:
undetectable		 2vaxK-1nfdB:
17.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WA2_B_SAMB1267_1
(NON-STRUCTURAL
PROTEIN 5)		 1nfd H57 FAB
(Mus
musculus) 		3 / 3 SER E 208
HIS E 189
ASP E 157
 None
 0.76A 2wa2B-1nfdE:
undetectable		 2wa2B-1nfdE:
23.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y03_A_5FWA601_1
(BETA-1 ADRENERGIC
RECEPTOR)		 1nfd H57 FAB
(Mus
musculus) 		5 / 12 VAL F 171
VAL F 191
SER F 189
ASN F 209
ASN F 162
 None
 1.45A 2y03A-1nfdF:
undetectable		 2y03A-1nfdF:
19.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y03_B_5FWB601_1
(BETA-1 ADRENERGIC
RECEPTOR)		 1nfd H57 FAB
(Mus
musculus) 		5 / 12 VAL F 171
VAL F 191
SER F 189
ASN F 209
ASN F 162
 None
 1.48A 2y03B-1nfdF:
undetectable		 2y03B-1nfdF:
19.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DQR_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1nfd H57 FAB
(Mus
musculus) 		4 / 7 VAL E 106
ARG E  61
VAL E  19
GLU E  83
 None
 1.09A 3dqrA-1nfdE:
undetectable
3dqrB-1nfdE:
undetectable		 3dqrA-1nfdE:
18.93
3dqrB-1nfdE:
18.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DQR_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1nfd H57 FAB
(Mus
musculus) 		4 / 7 GLU E  83
VAL E 106
ARG E  61
VAL E  19
 None
 1.14A 3dqrA-1nfdE:
undetectable
3dqrB-1nfdE:
undetectable		 3dqrA-1nfdE:
18.93
3dqrB-1nfdE:
18.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JX2_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1nfd H57 FAB
(Mus
musculus) 		4 / 7 VAL E 106
ARG E  61
VAL E  19
GLU E  83
 None
 0.98A 3jx2A-1nfdE:
undetectable
3jx2B-1nfdE:
undetectable		 3jx2A-1nfdE:
18.93
3jx2B-1nfdE:
18.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JX2_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1nfd H57 FAB
(Mus
musculus) 		4 / 7 GLU E  83
VAL E 106
ARG E  61
VAL E  19
 None
 1.08A 3jx2A-1nfdE:
0.0
3jx2B-1nfdE:
0.0		 3jx2A-1nfdE:
18.93
3jx2B-1nfdE:
18.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JX3_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1nfd H57 FAB
(Mus
musculus) 		4 / 7 VAL E 106
ARG E  61
VAL E  19
GLU E  83
 None
 1.06A 3jx3A-1nfdE:
0.0
3jx3B-1nfdE:
0.0		 3jx3A-1nfdE:
18.93
3jx3B-1nfdE:
18.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JX3_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1nfd H57 FAB
(Mus
musculus) 		4 / 7 GLU E  83
VAL E 106
ARG E  61
VAL E  19
 None
 1.05A 3jx3A-1nfdE:
0.0
3jx3B-1nfdE:
0.0		 3jx3A-1nfdE:
18.93
3jx3B-1nfdE:
18.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JX5_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1nfd H57 FAB
(Mus
musculus) 		4 / 7 VAL E 106
ARG E  61
VAL E  19
GLU E  83
 None
 1.04A 3jx5A-1nfdE:
0.0
3jx5B-1nfdE:
0.0		 3jx5A-1nfdE:
18.93
3jx5B-1nfdE:
18.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JX6_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1nfd H57 FAB
(Mus
musculus) 		4 / 7 VAL E 106
ARG E  61
VAL E  19
GLU E  83
 None
 0.99A 3jx6A-1nfdE:
undetectable
3jx6B-1nfdE:
undetectable		 3jx6A-1nfdE:
18.93
3jx6B-1nfdE:
18.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLJ_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1nfd H57 FAB
(Mus
musculus) 		4 / 7 VAL E 106
ARG E  61
VAL E  19
GLU E  83
 None
 0.99A 3nljA-1nfdE:
undetectable
3nljB-1nfdE:
undetectable		 3nljA-1nfdE:
18.93
3nljB-1nfdE:
18.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLP_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1nfd H57 FAB
(Mus
musculus) 		4 / 7 VAL E 106
ARG E  61
VAL E  19
GLU E  83
 None
 1.02A 3nlpA-1nfdE:
undetectable
3nlpB-1nfdE:
undetectable		 3nlpA-1nfdE:
18.93
3nlpB-1nfdE:
18.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLQ_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1nfd H57 FAB
(Mus
musculus) 		4 / 8 VAL E 106
ARG E  61
VAL E  19
GLU E  83
 None
 1.01A 3nlqA-1nfdE:
undetectable
3nlqB-1nfdE:
undetectable		 3nlqA-1nfdE:
18.93
3nlqB-1nfdE:
18.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLR_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1nfd H57 FAB
(Mus
musculus) 		4 / 7 VAL E 106
ARG E  61
VAL E  19
GLU E  83
 None
 1.04A 3nlrA-1nfdE:
0.0
3nlrB-1nfdE:
0.0		 3nlrA-1nfdE:
18.93
3nlrB-1nfdE:
18.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLR_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1nfd H57 FAB
(Mus
musculus) 		4 / 8 GLU E  83
VAL E 106
ARG E  61
VAL E  19
 None
 1.10A 3nlrA-1nfdE:
undetectable
3nlrB-1nfdE:
undetectable		 3nlrA-1nfdE:
18.93
3nlrB-1nfdE:
18.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CX3_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1nfd H57 FAB
(Mus
musculus) 		4 / 7 VAL E 106
ARG E  61
VAL E  19
GLU E  83
 None
 1.05A 4cx3A-1nfdE:
0.0
4cx3B-1nfdE:
0.0		 4cx3A-1nfdE:
18.93
4cx3B-1nfdE:
18.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CX3_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1nfd H57 FAB
(Mus
musculus) 		4 / 7 GLU E  83
VAL E 106
ARG E  61
VAL E  19
 None
 1.05A 4cx3A-1nfdE:
0.0
4cx3B-1nfdE:
0.0		 4cx3A-1nfdE:
18.93
4cx3B-1nfdE:
18.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CX4_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1nfd H57 FAB
(Mus
musculus) 		4 / 7 VAL E 106
ARG E  61
VAL E  19
GLU E  83
 None
 1.05A 4cx4A-1nfdE:
0.0
4cx4B-1nfdE:
0.0		 4cx4A-1nfdE:
18.93
4cx4B-1nfdE:
18.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CX4_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1nfd H57 FAB
(Mus
musculus) 		4 / 7 GLU E  83
VAL E 106
ARG E  61
VAL E  19
 None
 1.06A 4cx4A-1nfdE:
0.0
4cx4B-1nfdE:
0.0		 4cx4A-1nfdE:
18.93
4cx4B-1nfdE:
18.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D7B_A_TCWA1126_1
(TRANSTHYRETIN)		 1nfd H57 FAB
(Mus
musculus) 		4 / 6 LEU E 132
ALA E 130
LEU E 179
THR E 182
 None
 1.19A 4d7bB-1nfdE:
0.0		 4d7bB-1nfdE:
22.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EM2_A_SALA501_1
(UNCHARACTERIZED
HTH-TYPE
TRANSCRIPTIONAL
REGULATOR SAR2349)		 1nfd H57 FAB
(Mus
musculus) 		4 / 5 TYR F  90
LEU F  80
LEU F  82
ARG F  66
 None
 1.28A 4em2A-1nfdF:
undetectable		 4em2A-1nfdF:
17.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4J7X_F_SASF805_1
(SEPIAPTERIN
REDUCTASE)		 1nfd H57 FAB
(Mus
musculus) 		5 / 12 LEU E  96
PHE F 100
TRP F 103
ASP F 101
ASP F  99
 None
 1.17A 4j7xF-1nfdE:
undetectable		 4j7xF-1nfdE:
21.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4J7X_J_SASJ804_1
(SEPIAPTERIN
REDUCTASE)		 1nfd H57 FAB
(Mus
musculus) 		5 / 12 LEU E  96
PHE F 100
TRP F 103
ASP F 101
ASP F  99
 None
 1.16A 4j7xJ-1nfdE:
undetectable		 4j7xJ-1nfdE:
21.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LVC_C_ADNC501_2
(S-ADENOSYL-L-HOMOCYS
TEINE HYDROLASE
(SAHASE))		 1nfd N15 ALPHA-BETA
T-CELL RECEPTOR
(Mus
musculus) 		4 / 5 GLN A   5
THR A   4
THR A  30
LEU A  66
 None
 1.27A 4lvcC-1nfdA:
undetectable		 4lvcC-1nfdA:
18.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O0U_A_ADNA501_1
(AURORA KINASE A)		 1nfd H57 FAB
(Mus
musculus) 		4 / 6 ALA E 150
LEU E 179
THR E 182
LEU E 181
 None
 0.76A 4o0uA-1nfdE:
undetectable		 4o0uA-1nfdE:
21.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PTH_A_FOLA201_1
(DIHYDROFOLATE
REDUCTASE)		 1nfd H57 FAB
H57 FAB
(Mus
musculus;
Mus
musculus) 		3 / 3 ASP F 101
LEU E  46
PHE F 100
 None
 0.66A 4pthA-1nfdF:
undetectable		 4pthA-1nfdF:
19.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QZT_A_RTLA201_0
(RETINOL-BINDING
PROTEIN 2)		 1nfd H57 FAB
H57 FAB
(Mus
musculus;
Mus
musculus) 		5 / 12 ILE E  48
GLN E   6
TYR E  86
GLN F  39
LEU F  45
 None
 1.47A 4qztA-1nfdE:
0.0		 4qztA-1nfdE:
24.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XI3_D_29SD601_2
(ESTROGEN RECEPTOR)		 1nfd N15 ALPHA-BETA
T-CELL RECEPTOR
(Mus
musculus) 		3 / 3 LEU A 140
ASP A 137
ILE A 162
 None
 0.68A 4xi3D-1nfdA:
undetectable		 4xi3D-1nfdA:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ADD_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1nfd H57 FAB
(Mus
musculus) 		4 / 7 GLU E  83
VAL E 106
ARG E  61
VAL E  19
 None
 1.05A 5addA-1nfdE:
0.0
5addB-1nfdE:
undetectable		 5addA-1nfdE:
18.93
5addB-1nfdE:
18.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G0P_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1nfd H57 FAB
(Mus
musculus) 		4 / 7 VAL E 106
ARG E  61
VAL E  19
GLU E  83
 None
 1.06A 5g0pA-1nfdE:
undetectable
5g0pB-1nfdE:
undetectable		 5g0pA-1nfdE:
18.93
5g0pB-1nfdE:
18.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IZF_E_AZ1E2_1
(CAMP-DEPENDENT
PROTEIN KINASE
CATALYTIC SUBUNIT
ALPHA
6J9-ZEU-DAR-ACA-DAR-
NH2)		 1nfd N15 ALPHA-BETA
T-CELL RECEPTOR
(Mus
musculus) 		4 / 7 GLY B 109
GLY B   3
SER B   2
GLU A  41
 None
 0.76A 5izfA-1nfdB:
undetectable		 5izfA-1nfdB:
20.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KC0_A_RBFA303_2
(RIBOFLAVIN
TRANSPORTER RIBU)		 1nfd H57 FAB
(Mus
musculus) 		3 / 3 LYS E 160
LEU E 132
ILE E 155
 None
 0.71A 5kc0A-1nfdE:
undetectable		 5kc0A-1nfdE:
22.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L4I_B_6J3B201_0
(TRANSTHYRETIN)		 1nfd H57 FAB
(Mus
musculus) 		4 / 6 LEU E 132
ALA E 130
LEU E 179
THR E 182
 None
 1.17A 5l4iB-1nfdE:
4.0		 5l4iB-1nfdE:
21.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M5K_A_ADNA502_2
(ADENOSYLHOMOCYSTEINA
SE)		 1nfd N15 ALPHA-BETA
T-CELL RECEPTOR
(Mus
musculus) 		4 / 4 GLN A   5
THR A   4
THR A  30
LEU A  66
 None
 1.28A 5m5kA-1nfdA:
undetectable		 5m5kA-1nfdA:
18.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M5K_C_ADNC502_2
(ADENOSYLHOMOCYSTEINA
SE)		 1nfd N15 ALPHA-BETA
T-CELL RECEPTOR
(Mus
musculus) 		4 / 4 GLN A   5
THR A   4
THR A  30
LEU A  66
 None
 1.27A 5m5kC-1nfdA:
undetectable		 5m5kC-1nfdA:
18.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M66_B_ADNB502_2
(ADENOSYLHOMOCYSTEINA
SE)		 1nfd N15 ALPHA-BETA
T-CELL RECEPTOR
(Mus
musculus) 		4 / 4 GLN A   5
THR A   4
THR A  30
LEU A  66
 None
 1.30A 5m66B-1nfdA:
undetectable		 5m66B-1nfdA:
18.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N0X_B_SAMB501_1
(PEPTIDE
N-METHYLTRANSFERASE)		 1nfd H57 FAB
(Mus
musculus) 		3 / 3 SER E  90
ALA E  33
THR E  66
 None
 0.71A 5n0xB-1nfdE:
undetectable		 5n0xB-1nfdE:
19.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NOO_C_D16C402_1
(THYMIDYLATE SYNTHASE)		 1nfd H57 FAB
(Mus
musculus) 		4 / 6 TYR F  35
LEU F   4
GLY F 104
TYR F   3
 None
 1.03A 5nooC-1nfdF:
undetectable		 5nooC-1nfdF:
22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6A4I_B_TRPB403_0
(TRYPTOPHAN
2,3-DIOXYGENASE)		 1nfd N15 ALPHA-BETA
T-CELL RECEPTOR
H57 FAB
(Mus
musculus;
Mus
musculus) 		4 / 7 TRP F  33
ARG F  71
PRO F  52
PRO B 230
 None
 1.31A 6a4iB-1nfdF:
undetectable		 6a4iB-1nfdF:
17.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BRD_A_RFPA502_2
(RIFAMPIN
MONOOXYGENASE)		 1nfd N15 ALPHA-BETA
T-CELL RECEPTOR
(Mus
musculus) 		4 / 4 GLN B 213
VAL B 157
ARG A 134
ARG B 211
 NAG  B 251 (-3.5A)
None
None
None
 1.17A 6brdA-1nfdB:
undetectable		 6brdA-1nfdB:
15.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6ECF_I_DVAI3010_0
(VLM2
DODECADEPSIPEPTIDE)		 1nfd N15 ALPHA-BETA
T-CELL RECEPTOR
N15 ALPHA-BETA
T-CELL RECEPTOR
(Mus
musculus;
Mus
musculus) 		3 / 3 PHE A 146
ARG B 195
ALA A 116
 None
 0.77A 6ecfB-1nfdA:
undetectable		 6ecfB-1nfdA:
20.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GBN_A_ADNA501_2
(-)		 1nfd N15 ALPHA-BETA
T-CELL RECEPTOR
(Mus
musculus) 		4 / 5 GLN A   5
THR A   4
THR A  30
LEU A  66
 None
 1.29A 6gbnA-1nfdA:
undetectable		 6gbnA-1nfdA:
18.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GBN_D_ADND501_2
(-)		 1nfd N15 ALPHA-BETA
T-CELL RECEPTOR
(Mus
musculus) 		4 / 5 GLN A   5
THR A   4
THR A  30
LEU A  66
 None
 1.30A 6gbnD-1nfdA:
undetectable		 6gbnD-1nfdA:
18.89