SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1nfp'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A4L_D_DCFD1853_2
(ADENOSINE DEAMINASE)		 1nfp LUXF GENE PRODUCT
(Photobacterium
leiognathi) 		4 / 4 HIS A  50
LEU A 128
LEU A 130
LEU A 145
 None
 1.14A 1a4lD-1nfpA:
undetectable		 1a4lD-1nfpA:
21.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XF3_B_J01B500_1
(ORF12)		 1nfp LUXF GENE PRODUCT
(Photobacterium
leiognathi) 		5 / 9 HIS A 126
VAL A 124
ILE A 121
LEU A 106
ALA A  76
 None
 1.48A 2xf3B-1nfpA:
0.0		 2xf3B-1nfpA:
19.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XH9_B_J01B1436_1
(ORF12)		 1nfp LUXF GENE PRODUCT
(Photobacterium
leiognathi) 		5 / 9 HIS A 126
VAL A 124
ILE A 121
LEU A 106
ALA A  76
 None
 1.48A 2xh9B-1nfpA:
0.0		 2xh9B-1nfpA:
19.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XRZ_A_ACTA1467_0
(DEOXYRIBODIPYRIMIDIN
E PHOTOLYASE)		 1nfp LUXF GENE PRODUCT
(Photobacterium
leiognathi) 		4 / 5 ARG A  33
ASP A  38
ILE A 212
GLU A  30
 None
 0.98A 2xrzA-1nfpA:
undetectable
2xrzB-1nfpA:
0.2		 2xrzA-1nfpA:
20.12
2xrzB-1nfpA:
20.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HCN_B_CHDB2_0
(FERROCHELATASE,
MITOCHONDRIAL)		 1nfp LUXF GENE PRODUCT
(Photobacterium
leiognathi) 		3 / 3 LEU A  75
LEU A  93
ARG A 103
 None
 0.75A 3hcnB-1nfpA:
undetectable		 3hcnB-1nfpA:
19.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IWU_A_ACTA402_0
(MACROLIDE
2'-PHOSPHOTRANSFERAS
E II)		 1nfp LUXF GENE PRODUCT
(Photobacterium
leiognathi) 		4 / 6 PHE A  10
VAL A  45
MET A 211
ILE A  35
 None
 1.20A 5iwuA-1nfpA:
undetectable		 5iwuA-1nfpA:
20.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VLM_D_CVID301_0
(REGULATORY PROTEIN
TETR)		 1nfp LUXF GENE PRODUCT
(Photobacterium
leiognathi) 		5 / 12 LEU A  29
TYR A 148
VAL A   8
CYH A 197
ASP A  38
 None
 1.43A 5vlmD-1nfpA:
0.0		 5vlmD-1nfpA:
23.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DH0_A_017A101_2
(PROTEASE)		 1nfp LUXF GENE PRODUCT
(Photobacterium
leiognathi) 		3 / 3 LEU A 195
ASP A 215
ILE A  34
 None
 0.65A 6dh0B-1nfpA:
undetectable		 6dh0B-1nfpA:
19.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FGC_A_ACTA811_0
(GEPHYRIN)		 1nfp LUXF GENE PRODUCT
(Photobacterium
leiognathi) 		3 / 3 LEU A  93
LEU A  68
ARG A 127
 None
 0.51A 6fgcA-1nfpA:
0.0		 6fgcA-1nfpA:
19.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FGD_A_ACTA810_0
(GEPHYRIN)		 1nfp LUXF GENE PRODUCT
(Photobacterium
leiognathi) 		3 / 3 LEU A  93
LEU A  68
ARG A 127
 None
 0.49A 6fgdA-1nfpA:
undetectable		 6fgdA-1nfpA:
19.18