SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1ng0'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DRF_A_FOLA187_0
(DIHYDROFOLATE
REDUCTASE)		 1ng0 COAT PROTEIN
(Cocksfoot
mottle
virus) 		5 / 12 ALA A  94
SER A 239
ILE A 241
PRO A 110
LEU A 243
 ALA  A  94 ( 0.0A)
SER  A 239 ( 0.0A)
ILE  A 241 ( 0.7A)
PRO  A 110 ( 1.1A)
LEU  A 243 ( 0.6A)
 0.99A 1drfA-1ng0A:
undetectable		 1drfA-1ng0A:
23.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GAH_A_ACRA497_2
(GLUCOAMYLASE-471)		 1ng0 COAT PROTEIN
(Cocksfoot
mottle
virus) 		4 / 6 ALA A  94
SER A  85
TRP A 236
LEU A  95
 ALA  A  94 ( 0.0A)
SER  A  85 ( 0.0A)
TRP  A 236 ( 0.5A)
LEU  A  95 ( 0.6A)
 1.18A 1gahA-1ng0A:
undetectable		 1gahA-1ng0A:
20.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AQI_A_CHDA3_0
(FERROCHELATASE)		 1ng0 COAT PROTEIN
(Cocksfoot
mottle
virus) 		3 / 3 PRO A  92
LEU A  95
ARG A  97
 PRO  A  92 ( 1.1A)
LEU  A  95 ( 0.6A)
ARG  A  97 ( 0.6A)
 0.92A 3aqiA-1ng0A:
undetectable		 3aqiA-1ng0A:
19.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CB8_A_SAMA501_0
(PYRUVATE
FORMATE-LYASE
1-ACTIVATING ENZYME)		 1ng0 COAT PROTEIN
(Cocksfoot
mottle
virus) 		5 / 12 TYR A 213
ASN A 206
GLU A 203
ARG A 217
VAL A 214
 TYR  A 213 ( 1.3A)
ASN  A 206 ( 0.6A)
GLU  A 203 ( 0.5A)
ARG  A 217 ( 0.6A)
VAL  A 214 ( 0.6A)
 1.13A 3cb8A-1ng0A:
undetectable		 3cb8A-1ng0A:
20.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U88_A_CHDA611_0
(MENIN)		 1ng0 COAT PROTEIN
(Cocksfoot
mottle
virus) 		3 / 3 SER A 246
PHE A  64
LYS A 244
 SER  A 246 ( 0.0A)
PHE  A  64 ( 1.3A)
LYS  A 244 ( 0.0A)
 1.02A 3u88A-1ng0A:
undetectable		 3u88A-1ng0A:
19.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MMD_A_29EA603_1
(TRANSPORTER)		 1ng0 COAT PROTEIN
(Cocksfoot
mottle
virus) 		5 / 10 VAL A 180
ALA A 179
GLY A 233
SER A 166
GLY A 163
 VAL  A 180 ( 0.6A)
ALA  A 179 ( 0.0A)
GLY  A 233 ( 0.0A)
SER  A 166 ( 0.0A)
GLY  A 163 ( 0.0A)
 1.33A 4mmdA-1ng0A:
undetectable		 4mmdA-1ng0A:
18.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O1E_B_C2FB4000_0
(DIHYDROPTEROATE
SYNTHASE DHPS)		 1ng0 COAT PROTEIN
(Cocksfoot
mottle
virus) 		5 / 12 ILE A 115
ILE A 101
LEU A 243
GLY A  67
ILE A  69
 ILE  A 115 ( 0.4A)
ILE  A 101 ( 0.7A)
LEU  A 243 ( 0.6A)
GLY  A  67 ( 0.0A)
ILE  A  69 ( 0.7A)
 1.06A 4o1eB-1ng0A:
undetectable		 4o1eB-1ng0A:
19.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QOI_B_ML1B303_1
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 1ng0 COAT PROTEIN
(Cocksfoot
mottle
virus) 		5 / 11 GLY A 161
GLY A 162
GLY A 127
PHE A  76
ILE A 129
 GLY  A 161 ( 0.0A)
GLY  A 162 ( 0.0A)
GLY  A 127 ( 0.0A)
PHE  A  76 ( 1.3A)
ILE  A 129 ( 0.7A)
 1.16A 4qoiA-1ng0A:
undetectable
4qoiB-1ng0A:
undetectable		 4qoiA-1ng0A:
20.99
4qoiB-1ng0A:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FCT_B_C2FB402_1
(THYMIDYLATE SYNTHASE)		 1ng0 COAT PROTEIN
(Cocksfoot
mottle
virus) 		3 / 3 ASN A 158
ASP A 164
GLY A 177
 ASN  A 158 ( 0.6A)
ASP  A 164 ( 0.6A)
GLY  A 177 ( 0.0A)
 0.67A 5fctB-1ng0A:
undetectable		 5fctB-1ng0A:
21.23