SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1ngq'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DSD_C_DVAC2_0
(ACTINOMYCIN D)		 1ngq N1G9 (IGG1-LAMBDA)
(Mus
musculus) 		4 / 4 THR H 123
PRO H 125
THR H 124
PRO H 154
 None
 1.23A 1dsdC-1ngqH:
undetectable		 1dsdC-1ngqH:
13.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DSD_C_DVAC2_0
(ACTINOMYCIN D)		 1ngq N1G9 (IGG1-LAMBDA)
(Mus
musculus) 		4 / 4 THR H 124
PRO H 154
THR H 123
PRO H 125
 None
 1.16A 1dsdC-1ngqH:
undetectable		 1dsdC-1ngqH:
13.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DSD_C_DVAC8_0
(ACTINOMYCIN D)		 1ngq N1G9 (IGG1-LAMBDA)
(Mus
musculus) 		4 / 4 THR H 123
PRO H 125
THR H 124
PRO H 154
 None
 1.23A 1dsdC-1ngqH:
undetectable		 1dsdC-1ngqH:
13.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DSD_C_DVAC8_0
(ACTINOMYCIN D)		 1ngq N1G9 (IGG1-LAMBDA)
(Mus
musculus) 		4 / 4 THR H 124
PRO H 154
THR H 123
PRO H 125
 None
 1.16A 1dsdC-1ngqH:
undetectable		 1dsdC-1ngqH:
13.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y03_A_5FWA601_1
(BETA-1 ADRENERGIC
RECEPTOR)		 1ngq N1G9 (IGG1-LAMBDA)
(Mus
musculus) 		5 / 12 VAL H 170
VAL H 188
SER H 186
ASN H 203
ASN H 162
 None
 1.45A 2y03A-1ngqH:
undetectable		 2y03A-1ngqH:
21.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NYA_A_JTZA1203_1
(BETA-2 ADRENERGIC
RECEPTOR, LYSOZYME)		 1ngq N1G9 (IGG1-LAMBDA)
(Mus
musculus) 		5 / 12 VAL H 170
VAL H 188
SER H 186
ASN H 203
ASN H 162
 None
 1.39A 3nyaA-1ngqH:
undetectable		 3nyaA-1ngqH:
17.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LDO_A_ALEA1402_1
(LYSOZYME, BETA-2
ADRENERGIC RECEPTOR)		 1ngq N1G9 (IGG1-LAMBDA)
(Mus
musculus) 		5 / 10 VAL H 170
VAL H 188
SER H 186
ASN H 203
ASN H 162
 None
 1.49A 4ldoA-1ngqH:
undetectable		 4ldoA-1ngqH:
18.18
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4M7K_H_ACTH302_0
(10H10 HEAVY CHAIN)		 1ngq N1G9 (IGG1-LAMBDA)
(Mus
musculus) 		4 / 5 VAL H   2
TYR H  27
ARG H  98
TYR H 109
 None
 0.33A 4m7kH-1ngqH:
22.5		 4m7kH-1ngqH:
69.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XIW_D_LOCD503_1
(TUBULIN ALPHA-1B
CHAIN
TUBULIN BETA CHAIN)		 1ngq N1G9 (IGG1-LAMBDA)
(Mus
musculus) 		3 / 3 SER H 210
ALA H 205
VAL H 204
 None
 0.52A 5xiwC-1ngqH:
undetectable		 5xiwC-1ngqH:
16.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6H7M_B_68HB405_0
(BETA-1 ADRENERGIC
RECEPTOR)		 1ngq N1G9 (IGG1-LAMBDA)
(Mus
musculus) 		5 / 12 VAL H 170
VAL H 188
SER H 186
ASN H 203
ASN H 162
 None
 1.46A 6h7mB-1ngqH:
undetectable		 6h7mB-1ngqH:
19.40