SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1ngr'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z90_F_4LEF402_1
(GAMMA-AMINOBUTYRIC-A
CID RECEPTOR SUBUNIT
BETA-1)		 1ngr P75 LOW AFFINITY
NEUROTROPHIN
RECEPTOR
(Rattus
norvegicus) 		5 / 7 LEU A 360
ALA A 402
LEU A 364
ALA A 398
LEU A 352
 None
 0.91A 4z90F-1ngrA:
undetectable
4z90G-1ngrA:
undetectable
4z90H-1ngrA:
undetectable
4z90J-1ngrA:
undetectable		 4z90F-1ngrA:
15.56
4z90G-1ngrA:
15.56
4z90H-1ngrA:
15.56
4z90J-1ngrA:
15.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AY6_A_VORA501_1
(CYP51, STEROL
14ALPHA-DEMETHYLASE)		 1ngr P75 LOW AFFINITY
NEUROTROPHIN
RECEPTOR
(Rattus
norvegicus) 		5 / 9 TYR A 366
ALA A 402
ALA A 398
THR A 395
LEU A 385
 None
 1.46A 6ay6A-1ngrA:
undetectable		 6ay6A-1ngrA:
12.11