SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1nij'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JTV_A_TESA500_1
(17
BETA-HYDROXYSTEROID
DEHYDROGENASE TYPE 1)		 1nij HYPOTHETICAL PROTEIN
YJIA
(Escherichia
coli) 		4 / 8 VAL A 243
LEU A 316
TYR A 233
VAL A 229
 None
 1.11A 1jtvA-1nijA:
3.3		 1jtvA-1nijA:
23.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q23_B_FUAB703_2
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 1nij HYPOTHETICAL PROTEIN
YJIA
(Escherichia
coli) 		3 / 3 VAL A 133
ALA A 132
HIS A 170
 None
 0.58A 1q23C-1nijA:
undetectable		 1q23C-1nijA:
19.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q23_C_FUAC701_1
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 1nij HYPOTHETICAL PROTEIN
YJIA
(Escherichia
coli) 		4 / 4 ALA A 163
VAL A 133
ALA A 132
HIS A 170
 None
 0.80A 1q23A-1nijA:
1.9		 1q23A-1nijA:
19.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q23_E_FUAE706_2
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 1nij HYPOTHETICAL PROTEIN
YJIA
(Escherichia
coli) 		4 / 4 ALA A 163
VAL A 133
ALA A 132
HIS A 170
 None
 0.89A 1q23F-1nijA:
1.9		 1q23F-1nijA:
19.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q23_G_FUAG708_2
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 1nij HYPOTHETICAL PROTEIN
YJIA
(Escherichia
coli) 		3 / 3 VAL A 133
ALA A 132
HIS A 170
 None
 0.48A 1q23H-1nijA:
undetectable		 1q23H-1nijA:
19.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q23_I_FUAI707_1
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 1nij HYPOTHETICAL PROTEIN
YJIA
(Escherichia
coli) 		3 / 3 VAL A 133
ALA A 132
HIS A 170
 None
 0.50A 1q23G-1nijA:
2.0		 1q23G-1nijA:
19.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q23_J_FUAJ711_2
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 1nij HYPOTHETICAL PROTEIN
YJIA
(Escherichia
coli) 		4 / 4 ALA A 163
VAL A 133
ALA A 132
HIS A 170
 None
 0.78A 1q23K-1nijA:
2.0		 1q23K-1nijA:
19.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q23_K_FUAK712_2
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 1nij HYPOTHETICAL PROTEIN
YJIA
(Escherichia
coli) 		3 / 3 VAL A 133
ALA A 132
HIS A 170
 None
 0.72A 1q23L-1nijA:
2.0		 1q23L-1nijA:
19.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q23_L_FUAL710_1
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 1nij HYPOTHETICAL PROTEIN
YJIA
(Escherichia
coli) 		3 / 3 VAL A 133
ALA A 132
HIS A 170
 None
 0.44A 1q23J-1nijA:
1.8		 1q23J-1nijA:
19.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IXL_A_PACA5000_0
(ARYLMALONATE
DECARBOXYLASE)		 1nij HYPOTHETICAL PROTEIN
YJIA
(Escherichia
coli) 		5 / 10 PRO A 104
CYH A  98
THR A  99
VAL A 126
GLY A  11
 None
 1.47A 3ixlA-1nijA:
0.0		 3ixlA-1nijA:
23.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OJ4_A_DIFA501_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 1nij HYPOTHETICAL PROTEIN
YJIA
(Escherichia
coli) 		5 / 8 LEU A 169
LEU A 157
VAL A 130
ILE A 155
MET A 139
 None
 1.15A 4oj4A-1nijA:
undetectable		 4oj4A-1nijA:
24.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QZT_C_RTLC201_0
(RETINOL-BINDING
PROTEIN 2)		 1nij HYPOTHETICAL PROTEIN
YJIA
(Escherichia
coli) 		5 / 12 PHE A  91
ILE A  57
ALA A  34
THR A 110
LEU A  81
 None
 1.36A 4qztC-1nijA:
0.0		 4qztC-1nijA:
17.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R38_B_RBFB201_2
(BLUE-LIGHT-ACTIVATED
HISTIDINE KINASE 2)		 1nij HYPOTHETICAL PROTEIN
YJIA
(Escherichia
coli) 		4 / 8 THR A  55
ILE A  89
VAL A  95
LEU A  94
 None
 0.93A 4r38B-1nijA:
undetectable		 4r38B-1nijA:
19.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R38_C_RBFC201_2
(BLUE-LIGHT-ACTIVATED
HISTIDINE KINASE 2)		 1nij HYPOTHETICAL PROTEIN
YJIA
(Escherichia
coli) 		5 / 9 THR A  55
ILE A  89
VAL A  95
LEU A  94
ILE A  96
 None
 1.04A 4r38C-1nijA:
1.9		 4r38C-1nijA:
19.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XI3_D_29SD601_2
(ESTROGEN RECEPTOR)		 1nij HYPOTHETICAL PROTEIN
YJIA
(Escherichia
coli) 		3 / 3 LEU A  80
ASP A  85
ILE A  33
 None
 0.63A 4xi3D-1nijA:
undetectable		 4xi3D-1nijA:
21.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Y4D_A_CFFA411_1
(ENDOTHIAPEPSIN)		 1nij HYPOTHETICAL PROTEIN
YJIA
(Escherichia
coli) 		4 / 6 LEU A 117
LEU A 123
PHE A 111
PHE A 112
 None
 1.15A 4y4dA-1nijA:
0.0		 4y4dA-1nijA:
22.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JNC_D_ACTD305_0
(CARBONIC ANHYDRASE 4)		 1nij HYPOTHETICAL PROTEIN
YJIA
(Escherichia
coli) 		4 / 5 ALA A 180
ALA A 152
ILE A 155
LEU A 156
 None
 0.81A 5jncD-1nijA:
0.0		 5jncD-1nijA:
19.88