SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1njf'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A4L_B_DCFB853_2
(ADENOSINE DEAMINASE)		 1njf DNA POLYMERASE III
SUBUNIT GAMMA
(Escherichia
coli) 		4 / 5 HIS A  23
LEU A 178
LEU A  57
GLY A  50
 None
None
None
AGS  A 402 (-3.2A)
 1.15A 1a4lB-1njfA:
undetectable		 1a4lB-1njfA:
20.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1CEA_B_ACAB90_1
(PLASMINOGEN)		 1njf DNA POLYMERASE III
SUBUNIT GAMMA
(Escherichia
coli) 		4 / 7 ARG A  11
ASP A 126
ASP A  94
ARG A   8
 AGS  A 402 (-3.0A)
None
None
None
 1.38A 1ceaB-1njfA:
undetectable		 1ceaB-1njfA:
20.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JOM_A_FFOA161_0
(DIHYDROFOLATE
REDUCTASE)		 1njf DNA POLYMERASE III
SUBUNIT GAMMA
(Escherichia
coli) 		5 / 11 ALA A  55
GLU A  92
LEU A  90
LYS A 121
ILE A  93
 None
 1.12A 1jomA-1njfA:
undetectable		 1jomA-1njfA:
22.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OIP_B_MTXB609_1
(CHAIN A, CRYSTAL
STRUCTURE OF DHFR)		 1njf DNA POLYMERASE III
SUBUNIT GAMMA
(Escherichia
coli) 		5 / 12 LEU A 139
PHE A 136
SER A 135
THR A 156
THR A 165
 None
 1.17A 2oipB-1njfA:
undetectable		 2oipB-1njfA:
19.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OIP_C_MTXC613_1
(CHAIN A, CRYSTAL
STRUCTURE OF DHFR)		 1njf DNA POLYMERASE III
SUBUNIT GAMMA
(Escherichia
coli) 		5 / 12 LEU A 139
PHE A 136
SER A 135
THR A 156
THR A 165
 None
 1.21A 2oipC-1njfA:
undetectable		 2oipC-1njfA:
19.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HJ3_A_MTXA605_1
(CHAIN A, CRYSTAL
STRUCTURE OF DHFR)		 1njf DNA POLYMERASE III
SUBUNIT GAMMA
(Escherichia
coli) 		5 / 12 LEU A 139
PHE A 136
SER A 135
THR A 156
THR A 165
 None
 1.19A 3hj3A-1njfA:
undetectable		 3hj3A-1njfA:
19.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KR4_C_AICC401_1
(OUTER MEMBRANE
PROTEIN F)		 1njf DNA POLYMERASE III
SUBUNIT GAMMA
(Escherichia
coli) 		4 / 8 ARG A 215
ARG A  11
ARG A  56
ASP A  94
 AGS  A 402 (-3.3A)
AGS  A 402 (-3.0A)
None
None
 1.13A 4kr4C-1njfA:
0.0		 4kr4C-1njfA:
22.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z7F_C_FOLC201_0
(FOLATE ECF
TRANSPORTER)		 1njf DNA POLYMERASE III
SUBUNIT GAMMA
(Escherichia
coli) 		5 / 12 ALA A  95
THR A 157
THR A  52
LEU A 124
ARG A  56
 None
AGS  A 402 ( 4.8A)
AGS  A 402 (-3.7A)
None
None
 1.37A 4z7fC-1njfA:
0.1		 4z7fC-1njfA:
21.13