SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1njk'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WRK_B_TFPB203_1
(TROPONIN C, SLOW
SKELETAL AND CARDIAC
MUSCLES)		 1njk HYPOTHETICAL PROTEIN
YBAW
(Escherichia
coli) 		4 / 5 PHE A 106
LEU A  76
MET A  44
SER A  40
 None
 1.24A 1wrkB-1njkA:
undetectable		 1wrkB-1njkA:
21.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HRC_A_CHDA702_0
(FERROCHELATASE)		 1njk HYPOTHETICAL PROTEIN
YBAW
(Escherichia
coli) 		4 / 7 MET A  44
ARG A 124
LEU A  79
VAL A 131
 None
 1.27A 2hrcA-1njkA:
undetectable		 2hrcA-1njkA:
19.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RGL_A_GLYA301_0
(GLYCYL-TRNA
SYNTHETASE ALPHA
SUBUNIT)		 1njk HYPOTHETICAL PROTEIN
YBAW
(Escherichia
coli) 		4 / 8 GLN A   2
GLN A   4
GLU A  93
THR A  71
 None
 0.93A 3rglA-1njkA:
undetectable		 3rglA-1njkA:
19.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WW7_A_ACTA305_0
(EKC/KEOPS COMPLEX
SUBUNIT BUD32)		 1njk HYPOTHETICAL PROTEIN
YBAW
(Escherichia
coli) 		4 / 6 LEU A  24
LEU A  27
GLU A  28
ILE A 104
 None
 0.86A 4ww7A-1njkA:
0.0		 4ww7A-1njkA:
22.41