SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1nkl'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A52_A_ESTA1_1
(ESTROGEN RECEPTOR)		 1nkl NK-LYSIN
(Sus
scrofa) 		5 / 10 MET A  49
GLU A  24
LEU A  61
ILE A  69
LEU A  14
 None
 0.98A 1a52A-1nklA:
undetectable		 1a52A-1nklA:
15.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A52_B_ESTB2_1
(ESTROGEN RECEPTOR)		 1nkl NK-LYSIN
(Sus
scrofa) 		5 / 10 MET A  49
GLU A  24
LEU A  61
ILE A  69
LEU A  14
 None
 0.94A 1a52B-1nklA:
undetectable		 1a52B-1nklA:
15.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ERE_A_ESTA600_1
(ESTROGEN RECEPTOR)		 1nkl NK-LYSIN
(Sus
scrofa) 		5 / 9 MET A  49
GLU A  24
LEU A  61
ILE A  69
LEU A  14
 None
 0.98A 1ereA-1nklA:
0.6		 1ereA-1nklA:
15.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ERE_B_ESTB600_1
(ESTROGEN RECEPTOR)		 1nkl NK-LYSIN
(Sus
scrofa) 		5 / 9 MET A  49
GLU A  24
LEU A  61
ILE A  69
LEU A  14
 None
 0.99A 1ereB-1nklA:
0.6		 1ereB-1nklA:
15.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ERE_C_ESTC600_1
(ESTROGEN RECEPTOR)		 1nkl NK-LYSIN
(Sus
scrofa) 		5 / 9 MET A  49
GLU A  24
LEU A  61
ILE A  69
LEU A  14
 None
 0.97A 1ereC-1nklA:
0.6		 1ereC-1nklA:
15.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ERE_D_ESTD600_1
(ESTROGEN RECEPTOR)		 1nkl NK-LYSIN
(Sus
scrofa) 		5 / 9 MET A  49
GLU A  24
LEU A  61
ILE A  69
LEU A  14
 None
 0.98A 1ereD-1nklA:
0.6		 1ereD-1nklA:
15.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1G50_B_ESTB1600_1
(ESTROGEN RECEPTOR)		 1nkl NK-LYSIN
(Sus
scrofa) 		5 / 12 MET A  49
GLU A  24
LEU A  61
ILE A  69
LEU A  14
 None
 1.27A 1g50B-1nklA:
undetectable		 1g50B-1nklA:
13.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MZ9_A_VDYA1002_2
(CARTILAGE OLIGOMERIC
MATRIX PROTEIN)		 1nkl NK-LYSIN
(Sus
scrofa) 		3 / 3 ILE A  11
LEU A  14
VAL A  18
 None
 0.33A 1mz9B-1nklA:
undetectable		 1mz9B-1nklA:
23.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2J7X_A_ESTA1454_1
(ESTROGEN RECEPTOR
BETA)		 1nkl NK-LYSIN
(Sus
scrofa) 		5 / 12 MET A  49
GLU A  24
LEU A  61
ILE A  69
LEU A  14
 None
 1.03A 2j7xA-1nklA:
0.6		 2j7xA-1nklA:
14.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QXS_A_RALA600_1
(ESTROGEN RECEPTOR)		 1nkl NK-LYSIN
(Sus
scrofa) 		5 / 12 MET A  49
GLU A  24
LEU A  61
ILE A  69
LEU A  14
 None
 1.15A 2qxsA-1nklA:
undetectable		 2qxsA-1nklA:
15.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QXS_B_RALB600_1
(ESTROGEN RECEPTOR)		 1nkl NK-LYSIN
(Sus
scrofa) 		5 / 12 MET A  49
GLU A  24
LEU A  61
ILE A  69
LEU A  14
 None
 1.15A 2qxsB-1nklA:
undetectable		 2qxsB-1nklA:
15.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YJA_B_ESTB1550_1
(ESTROGEN RECEPTOR)		 1nkl NK-LYSIN
(Sus
scrofa) 		5 / 12 MET A  49
GLU A  24
LEU A  61
ILE A  69
LEU A  14
 None
 1.04A 2yjaB-1nklA:
undetectable		 2yjaB-1nklA:
16.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3Q95_A_ESLA700_1
(ESTROGEN RECEPTOR)		 1nkl NK-LYSIN
(Sus
scrofa) 		5 / 12 MET A  49
GLU A  24
LEU A  61
ILE A  69
LEU A  14
 None
 1.07A 3q95A-1nklA:
undetectable		 3q95A-1nklA:
14.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3Q95_B_ESLB700_1
(ESTROGEN RECEPTOR)		 1nkl NK-LYSIN
(Sus
scrofa) 		5 / 12 MET A  49
GLU A  24
LEU A  61
ILE A  69
LEU A  14
 None
 1.02A 3q95B-1nklA:
undetectable		 3q95B-1nklA:
14.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4J24_A_ESTA600_1
(ESTROGEN RECEPTOR
BETA)		 1nkl NK-LYSIN
(Sus
scrofa) 		5 / 12 MET A  49
GLU A  24
LEU A  61
ILE A  69
LEU A  14
 None
 1.04A 4j24A-1nklA:
undetectable		 4j24A-1nklA:
12.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4J24_B_ESTB600_1
(ESTROGEN RECEPTOR
BETA)		 1nkl NK-LYSIN
(Sus
scrofa) 		5 / 12 MET A  49
GLU A  24
LEU A  61
ILE A  69
LEU A  14
 None
 1.06A 4j24B-1nklA:
undetectable		 4j24B-1nklA:
12.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4J24_C_ESTC600_1
(ESTROGEN RECEPTOR
BETA)		 1nkl NK-LYSIN
(Sus
scrofa) 		5 / 12 MET A  49
GLU A  24
LEU A  61
ILE A  69
LEU A  14
 None
 1.05A 4j24C-1nklA:
undetectable		 4j24C-1nklA:
12.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4J26_A_ESTA600_1
(ESTROGEN RECEPTOR
BETA)		 1nkl NK-LYSIN
(Sus
scrofa) 		5 / 12 MET A  49
GLU A  24
LEU A  61
ILE A  69
LEU A  14
 None
 1.04A 4j26A-1nklA:
0.6		 4j26A-1nklA:
12.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4J26_B_ESTB600_1
(ESTROGEN RECEPTOR
BETA)		 1nkl NK-LYSIN
(Sus
scrofa) 		5 / 12 MET A  49
GLU A  24
LEU A  61
ILE A  69
LEU A  14
 None
 1.04A 4j26B-1nklA:
undetectable		 4j26B-1nklA:
12.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PXM_B_ESTB2000_1
(ESTROGEN RECEPTOR)		 1nkl NK-LYSIN
(Sus
scrofa) 		5 / 11 MET A  49
GLU A  24
LEU A  61
ILE A  69
LEU A  14
 None
 0.98A 4pxmB-1nklA:
0.5		 4pxmB-1nklA:
14.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DXB_B_ESTB601_1
(ESTROGEN RECEPTOR)		 1nkl NK-LYSIN
(Sus
scrofa) 		5 / 11 MET A  49
GLU A  24
LEU A  61
ILE A  69
LEU A  14
 None
 1.02A 5dxbB-1nklA:
undetectable		 5dxbB-1nklA:
13.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DXE_A_ESTA1000_1
(ESTROGEN RECEPTOR)		 1nkl NK-LYSIN
(Sus
scrofa) 		4 / 8 MET A  49
GLU A  24
LEU A  61
LEU A  14
 None
 1.06A 5dxeA-1nklA:
undetectable		 5dxeA-1nklA:
13.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GTR_A_ESTA601_1
(ESTROGEN RECEPTOR)		 1nkl NK-LYSIN
(Sus
scrofa) 		5 / 12 MET A  49
GLU A  24
LEU A  61
ILE A  69
LEU A  14
 None
 1.05A 5gtrA-1nklA:
0.7		 5gtrA-1nklA:
16.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TOA_B_ESTB601_1
(ESTROGEN RECEPTOR
BETA)		 1nkl NK-LYSIN
(Sus
scrofa) 		5 / 12 MET A  49
GLU A  24
LEU A  61
ILE A  69
LEU A  14
 None
 1.14A 5toaB-1nklA:
undetectable		 5toaB-1nklA:
17.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CBZ_A_ESTA601_1
(ESTROGEN RECEPTOR)		 1nkl NK-LYSIN
(Sus
scrofa) 		4 / 8 MET A  49
GLU A  24
LEU A  61
LEU A  14
 None
 0.98A 6cbzA-1nklA:
undetectable		 6cbzA-1nklA:
20.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CBZ_B_ESTB602_1
(ESTROGEN RECEPTOR)		 1nkl NK-LYSIN
(Sus
scrofa) 		5 / 10 MET A  49
GLU A  24
LEU A  61
ILE A  69
LEU A  14
 None
 1.01A 6cbzB-1nklA:
undetectable		 6cbzB-1nklA:
20.24