SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1nkp'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2J5M_A_ACTA1321_0
(CHLOROPEROXIDASE)		 1nkp MYC PROTO-ONCOGENE
PROTEIN
MAX PROTEIN
(Homo
sapiens;
Homo
sapiens) 		4 / 6 LEU A 924
PHE B 222
ILE B 242
ALA B 246
 None
 0.91A 2j5mA-1nkpA:
undetectable		 2j5mA-1nkpA:
12.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2J5M_A_ACTA1321_0
(CHLOROPEROXIDASE)		 1nkp MYC PROTO-ONCOGENE
PROTEIN
MAX PROTEIN
(Homo
sapiens;
Homo
sapiens) 		4 / 6 LEU B 225
PHE A 921
ILE A 942
ALA A 946
 None
 0.90A 2j5mA-1nkpB:
undetectable		 2j5mA-1nkpB:
13.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OZW_A_KKKA413_1
(FLAVOHEMOGLOBIN)		 1nkp MAX PROTEIN
MYC PROTO-ONCOGENE
PROTEIN
(Homo
sapiens) 		4 / 8 ILE A 942
ALA A 923
LEU A 924
LEU B 225
 None
 0.84A 3ozwA-1nkpA:
undetectable		 3ozwA-1nkpA:
12.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MMC_A_29JA604_1
(TRANSPORTER)		 1nkp MAX PROTEIN
(Homo
sapiens) 		4 / 7 LEU B 267
ASP B 266
ASP B 263
THR B 259
 None
 0.88A 4mmcA-1nkpB:
undetectable		 4mmcA-1nkpB:
9.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KC0_A_RBFA303_2
(RIBOFLAVIN
TRANSPORTER RIBU)		 1nkp MAX PROTEIN
MYC PROTO-ONCOGENE
PROTEIN
(Homo
sapiens) 		3 / 3 LYS A 945
LEU B 243
ILE B 218
 None
 0.77A 5kc0A-1nkpA:
undetectable		 5kc0A-1nkpA:
18.44