SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1nkq'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JGS_A_SALA256_1
(MULTIPLE ANTIBIOTIC
RESISTANCE PROTEIN
MARR)		 1nkq HYPOTHETICAL 28.8
KDA PROTEIN IN
PSD1-SKO1 INTERGENIC
REGION
(Saccharomyces
cerevisiae) 		4 / 7 VAL A 116
LEU A  90
THR A 214
VAL A  94
 None
 0.96A 1jgsA-1nkqA:
0.0		 1jgsA-1nkqA:
17.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PBK_A_RAPA225_1
(FKBP25)		 1nkq HYPOTHETICAL 28.8
KDA PROTEIN IN
PSD1-SKO1 INTERGENIC
REGION
(Saccharomyces
cerevisiae) 		6 / 12 LEU A 122
GLY A  74
VAL A  45
ILE A  44
ALA A  91
ILE A 211
 None
 1.25A 1pbkA-1nkqA:
undetectable		 1pbkA-1nkqA:
20.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DCF_A_ACAA501_1
(6-AMINOHEXANOATE-DIM
ER HYDROLASE)		 1nkq HYPOTHETICAL 28.8
KDA PROTEIN IN
PSD1-SKO1 INTERGENIC
REGION
(Saccharomyces
cerevisiae) 		4 / 6 ALA A  91
TYR A   5
ILE A 212
ILE A  93
 None
 0.95A 2dcfA-1nkqA:
undetectable		 2dcfA-1nkqA:
20.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PIW_A_T3A932_1
(ANDROGEN RECEPTOR)		 1nkq HYPOTHETICAL 28.8
KDA PROTEIN IN
PSD1-SKO1 INTERGENIC
REGION
(Saccharomyces
cerevisiae) 		4 / 6 LEU A 197
VAL A 109
ILE A 113
ILE A 212
 None
 0.71A 2piwA-1nkqA:
undetectable		 2piwA-1nkqA:
21.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZM7_A_ACAA501_1
(6-AMINOHEXANOATE-DIM
ER HYDROLASE)		 1nkq HYPOTHETICAL 28.8
KDA PROTEIN IN
PSD1-SKO1 INTERGENIC
REGION
(Saccharomyces
cerevisiae) 		4 / 7 ALA A  91
TYR A   5
ILE A 212
ILE A  93
 None
 1.00A 2zm7A-1nkqA:
0.0		 2zm7A-1nkqA:
20.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZM8_A_ACAA511_1
(6-AMINOHEXANOATE-DIM
ER HYDROLASE)		 1nkq HYPOTHETICAL 28.8
KDA PROTEIN IN
PSD1-SKO1 INTERGENIC
REGION
(Saccharomyces
cerevisiae) 		4 / 8 ALA A  91
TYR A   5
ILE A 212
ILE A  93
 None
 1.00A 2zm8A-1nkqA:
undetectable		 2zm8A-1nkqA:
20.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZMA_A_ACAA501_1
(6-AMINOHEXANOATE-DIM
ER HYDROLASE)		 1nkq HYPOTHETICAL 28.8
KDA PROTEIN IN
PSD1-SKO1 INTERGENIC
REGION
(Saccharomyces
cerevisiae) 		4 / 8 ALA A  91
TYR A   5
ILE A 212
ILE A  93
 None
 0.95A 2zmaA-1nkqA:
undetectable		 2zmaA-1nkqA:
20.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KP6_A_SALA3002_1
(TRANSCRIPTIONAL
REGULATOR TCAR)		 1nkq HYPOTHETICAL 28.8
KDA PROTEIN IN
PSD1-SKO1 INTERGENIC
REGION
(Saccharomyces
cerevisiae) 		5 / 8 LEU A  90
VAL A 154
ILE A 240
VAL A 241
LEU A 118
 None
 1.42A 3kp6A-1nkqA:
undetectable
3kp6B-1nkqA:
undetectable		 3kp6A-1nkqA:
21.32
3kp6B-1nkqA:
21.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XJ7_A_ADNA303_1
(5'/3'-NUCLEOTIDASE
SURE)		 1nkq HYPOTHETICAL 28.8
KDA PROTEIN IN
PSD1-SKO1 INTERGENIC
REGION
(Saccharomyces
cerevisiae) 		5 / 10 TYR A   3
ILE A  44
PRO A  73
LEU A   6
LEU A  66
 None
 1.19A 4xj7A-1nkqA:
undetectable
4xj7B-1nkqA:
undetectable		 4xj7A-1nkqA:
23.21
4xj7B-1nkqA:
23.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XJ7_D_ADND303_1
(5'/3'-NUCLEOTIDASE
SURE)		 1nkq HYPOTHETICAL 28.8
KDA PROTEIN IN
PSD1-SKO1 INTERGENIC
REGION
(Saccharomyces
cerevisiae) 		5 / 10 LEU A   6
LEU A  66
TYR A   3
ILE A  44
PRO A  73
 None
 1.15A 4xj7C-1nkqA:
undetectable
4xj7D-1nkqA:
undetectable		 4xj7C-1nkqA:
23.21
4xj7D-1nkqA:
23.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XUM_A_IMNA502_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 1nkq HYPOTHETICAL 28.8
KDA PROTEIN IN
PSD1-SKO1 INTERGENIC
REGION
(Saccharomyces
cerevisiae) 		4 / 7 GLU A  89
ILE A  12
LEU A  66
ILE A 150
 CA  A 260 ( 2.6A)
None
None
None
 0.89A 4xumA-1nkqA:
undetectable		 4xumA-1nkqA:
21.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HRQ_G_IPHG101_0
(INSULIN A-CHAIN
INSULIN B-CHAIN)		 1nkq HYPOTHETICAL 28.8
KDA PROTEIN IN
PSD1-SKO1 INTERGENIC
REGION
(Saccharomyces
cerevisiae) 		4 / 6 LEU A 234
CYH A 231
CYH A 174
LEU A 118
 None
 1.24A 5hrqD-1nkqA:
undetectable
5hrqG-1nkqA:
undetectable
5hrqH-1nkqA:
undetectable		 5hrqD-1nkqA:
9.78
5hrqG-1nkqA:
6.25
5hrqH-1nkqA:
9.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IEN_B_VDYB201_1
(CDL2.2)		 1nkq HYPOTHETICAL 28.8
KDA PROTEIN IN
PSD1-SKO1 INTERGENIC
REGION
(Saccharomyces
cerevisiae) 		5 / 10 ILE A 211
LEU A 213
VAL A 172
LEU A 233
LEU A   6
 None
 1.17A 5ienB-1nkqA:
0.0		 5ienB-1nkqA:
18.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OM2_B_DXTB501_1
(ALPHA-1-ANTICHYMOTRY
PSIN)		 1nkq HYPOTHETICAL 28.8
KDA PROTEIN IN
PSD1-SKO1 INTERGENIC
REGION
(Saccharomyces
cerevisiae) 		5 / 9 VAL A 109
LEU A 166
PHE A 170
VAL A 116
ILE A 113
 None
 1.10A 5om2A-1nkqA:
undetectable
5om2B-1nkqA:
undetectable		 5om2A-1nkqA:
16.22
5om2B-1nkqA:
14.60