SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1nku'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NC3_A_ERMA1202_1
(CHIMERA PROTEIN OF
HUMAN
5-HYDROXYTRYPTAMINE
RECEPTOR 2B AND E.
COLI SOLUBLE
CYTOCHROME B562)		 1nku 3-METHYLADENINE DNA
GLYCOSYLASE I (TAG)
(Escherichia
coli) 		5 / 12 LEU A 149
VAL A 116
SER A 118
PHE A 165
MET A 166
 None
 1.34A 4nc3A-1nkuA:
0.0		 4nc3A-1nkuA:
17.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HFJ_A_SAMA301_0
(ADENINE SPECIFIC DNA
METHYLTRANSFERASE
(DPNA))		 1nku 3-METHYLADENINE DNA
GLYCOSYLASE I (TAG)
(Escherichia
coli) 		5 / 12 ALA A 148
ASP A 114
PHE A 115
THR A  26
TYR A 102
 None
 1.24A 5hfjA-1nkuA:
undetectable		 5hfjA-1nkuA:
21.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HFJ_B_SAMB301_0
(ADENINE SPECIFIC DNA
METHYLTRANSFERASE
(DPNA))		 1nku 3-METHYLADENINE DNA
GLYCOSYLASE I (TAG)
(Escherichia
coli) 		5 / 12 ALA A 148
ASP A 114
PHE A 115
THR A  26
TYR A 102
 None
 1.33A 5hfjB-1nkuA:
undetectable		 5hfjB-1nkuA:
21.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HFJ_G_SAMG301_0
(ADENINE SPECIFIC DNA
METHYLTRANSFERASE
(DPNA))		 1nku 3-METHYLADENINE DNA
GLYCOSYLASE I (TAG)
(Escherichia
coli) 		5 / 12 ALA A 148
ASP A 114
PHE A 115
THR A  26
TYR A 102
 None
 1.33A 5hfjG-1nkuA:
undetectable		 5hfjG-1nkuA:
21.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HFJ_H_SAMH301_0
(ADENINE SPECIFIC DNA
METHYLTRANSFERASE
(DPNA))		 1nku 3-METHYLADENINE DNA
GLYCOSYLASE I (TAG)
(Escherichia
coli) 		5 / 12 ALA A 148
ASP A 114
PHE A 115
THR A  26
TYR A 102
 None
 1.32A 5hfjH-1nkuA:
undetectable		 5hfjH-1nkuA:
21.95