SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1nkz'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MZ9_A_VDYA1002_2
(CARTILAGE OLIGOMERIC
MATRIX PROTEIN)		 1nkz LIGHT-HARVESTING
PROTEIN B-800/850,
ALPHA CHAIN
(Rhodoblastus
acidophilus) 		3 / 3 ILE A  16
LEU A  19
VAL A  23
 None
None
RG1  B 401 ( 4.5A)
 0.21A 1mz9B-1nkzA:
2.8		 1mz9B-1nkzA:
17.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1S9P_B_DESB459_2
(ESTROGEN-RELATED
RECEPTOR GAMMA)		 1nkz LIGHT-HARVESTING
PROTEIN B-800/850,
ALPHA CHAIN
LIGHT-HARVESTING
PROTEIN B-800/850,
BETA CHAIN
(Rhodoblastus
acidophilus) 		3 / 3 LEU A  19
HIS B  12
ILE A   6
 None
CXM  A   1 ( 4.0A)
BCL  A 307 ( 4.1A)
 0.62A 1s9pB-1nkzA:
undetectable		 1s9pB-1nkzA:
13.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6D6T_D_FYPD406_0
(GAMMA-AMINOBUTYRIC
ACID RECEPTOR
SUBUNIT
ALPHA-1,GAMMA-AMINOB
UTYRIC ACID RECEPTOR
SUBUNIT ALPHA-1
HUMAN GABA-A
RECEPTOR SUBUNIT
GAMMA-2)		 1nkz LIGHT-HARVESTING
PROTEIN B-800/850,
ALPHA CHAIN
LIGHT-HARVESTING
PROTEIN B-800/850,
BETA CHAIN
(Rhodoblastus
acidophilus;
Rhodoblastus
acidophilus) 		5 / 11 HIS A  31
THR B  37
TYR A  44
PHE A  41
THR A  38
 BCL  B 302 (-3.2A)
RG1  A 404 (-3.8A)
RG1  A 404 ( 3.8A)
BCL  A 301 (-4.0A)
None
 1.32A 6d6tD-1nkzA:
undetectable
6d6tE-1nkzA:
undetectable		 6d6tD-1nkzA:
9.04
6d6tE-1nkzA:
11.07