SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1nl3'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DZM_A_BZMA600_0
(ODORANT-BINDING
PROTEIN)		 1nl3 PREPROTEIN
TRANSLOCASE SECA 1
SUBUNIT
(Mycobacterium
tuberculosis) 		4 / 8 ILE A 393
MET A 371
GLY A  89
LEU A  93
 None
 0.96A 1dzmA-1nl3A:
undetectable		 1dzmA-1nl3A:
10.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EII_A_RTLA135_1
(CELLULAR
RETINOL-BINDING
PROTEIN II)		 1nl3 PREPROTEIN
TRANSLOCASE SECA 1
SUBUNIT
(Mycobacterium
tuberculosis) 		4 / 7 GLN A 404
SER A 405
TYR A 583
GLN A 431
 None
 1.33A 1eiiA-1nl3A:
undetectable		 1eiiA-1nl3A:
9.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GSF_C_EAAC223_1
(GLUTATHIONE
TRANSFERASE A1-1)		 1nl3 PREPROTEIN
TRANSLOCASE SECA 1
SUBUNIT
(Mycobacterium
tuberculosis) 		4 / 8 PHE A 815
GLY A 811
LEU A 789
MET A 648
 None
 0.94A 1gsfC-1nl3A:
undetectable		 1gsfC-1nl3A:
13.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NH8_A_HISA289_0
(ATP
PHOSPHORIBOSYLTRANSF
ERASE)		 1nl3 PREPROTEIN
TRANSLOCASE SECA 1
SUBUNIT
(Mycobacterium
tuberculosis) 		4 / 5 ASP A  30
LEU A  39
ALA A  68
LEU A  27
 None
 1.14A 1nh8A-1nl3A:
0.0		 1nh8A-1nl3A:
15.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1VQ1_A_SAMA301_1
(N5-GLUTAMINE
METHYLTRANSFERASE,
HEMK)		 1nl3 PREPROTEIN
TRANSLOCASE SECA 1
SUBUNIT
(Mycobacterium
tuberculosis) 		3 / 3 GLY A 575
ASP A 576
ASN A 396
 None
 0.64A 1vq1A-1nl3A:
undetectable		 1vq1A-1nl3A:
16.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1X7P_B_SAMB302_0
(RRNA
METHYLTRANSFERASE)		 1nl3 PREPROTEIN
TRANSLOCASE SECA 1
SUBUNIT
(Mycobacterium
tuberculosis) 		5 / 10 ASP A 138
GLY A 143
ILE A 206
MET A 371
ALA A 115
 None
 1.05A 1x7pA-1nl3A:
undetectable
1x7pB-1nl3A:
undetectable		 1x7pA-1nl3A:
16.34
1x7pB-1nl3A:
16.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XL6_B_SPMB3001_1
(INWARD RECTIFIER
POTASSIUM CHANNEL)		 1nl3 PREPROTEIN
TRANSLOCASE SECA 1
SUBUNIT
(Mycobacterium
tuberculosis) 		4 / 5 ALA A 294
TYR A 290
ALA A 239
TYR A 235
 None
 1.06A 1xl6A-1nl3A:
2.6
1xl6B-1nl3A:
undetectable		 1xl6A-1nl3A:
15.60
1xl6B-1nl3A:
15.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AVV_E_MK1E902_4
(POL POLYPROTEIN)		 1nl3 PREPROTEIN
TRANSLOCASE SECA 1
SUBUNIT
(Mycobacterium
tuberculosis) 		3 / 3 ARG A 661
VAL A 774
GLY A 828
 None
 0.57A 2avvE-1nl3A:
undetectable		 2avvE-1nl3A:
7.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NYR_B_SVRB401_1
(NAD-DEPENDENT
DEACETYLASE
SIRTUIN-5)		 1nl3 PREPROTEIN
TRANSLOCASE SECA 1
SUBUNIT
(Mycobacterium
tuberculosis) 		5 / 12 ALA A 135
THR A 129
ALA A 205
PHE A 362
TYR A 361
 None
 1.01A 2nyrA-1nl3A:
undetectable		 2nyrA-1nl3A:
13.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WLK_B_SPMB1302_1
(ATP-SENSITIVE INWARD
RECTIFIER POTASSIUM
CHANNEL 10)		 1nl3 PREPROTEIN
TRANSLOCASE SECA 1
SUBUNIT
(Mycobacterium
tuberculosis) 		4 / 4 ALA A 294
TYR A 290
ALA A 239
TYR A 235
 None
 1.04A 2wlkA-1nl3A:
3.2
2wlkB-1nl3A:
2.8		 2wlkA-1nl3A:
15.60
2wlkB-1nl3A:
15.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XFH_A_CL6A1413_1
(ERYTHROMYCIN B/D
C-12 HYDROXYLASE)		 1nl3 PREPROTEIN
TRANSLOCASE SECA 1
SUBUNIT
(Mycobacterium
tuberculosis) 		4 / 6 HIS A 263
ALA A 700
ALA A 704
THR A 707
 None
 1.00A 2xfhA-1nl3A:
undetectable		 2xfhA-1nl3A:
19.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DEU_A_SALA301_1
(TRANSCRIPTIONAL
REGULATOR SLYA)		 1nl3 PREPROTEIN
TRANSLOCASE SECA 1
SUBUNIT
(Mycobacterium
tuberculosis) 		4 / 6 ARG A 652
ILE A 655
TRP A 779
HIS A 782
 None
 1.12A 3deuA-1nl3A:
1.0		 3deuA-1nl3A:
10.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EKP_B_478B200_1
(PROTEASE)		 1nl3 PREPROTEIN
TRANSLOCASE SECA 1
SUBUNIT
(Mycobacterium
tuberculosis) 		5 / 8 LEU A 157
GLY A 154
ALA A 168
ILE A 127
ILE A 156
 None
 1.18A 3ekpA-1nl3A:
undetectable		 3ekpA-1nl3A:
8.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ERD_A_DESA600_1
(ESTROGEN RECEPTOR
ALPHA)		 1nl3 PREPROTEIN
TRANSLOCASE SECA 1
SUBUNIT
(Mycobacterium
tuberculosis) 		5 / 12 MET A 648
ARG A 660
HIS A 782
LEU A 783
MET A 786
 None
 0.96A 3erdA-1nl3A:
undetectable		 3erdA-1nl3A:
13.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ERD_B_DESB800_1
(ESTROGEN RECEPTOR
ALPHA)		 1nl3 PREPROTEIN
TRANSLOCASE SECA 1
SUBUNIT
(Mycobacterium
tuberculosis) 		5 / 10 MET A 648
ARG A 660
HIS A 782
LEU A 783
MET A 786
 None
 0.96A 3erdB-1nl3A:
0.1		 3erdB-1nl3A:
13.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G2O_A_SAMA500_0
(PCZA361.24)		 1nl3 PREPROTEIN
TRANSLOCASE SECA 1
SUBUNIT
(Mycobacterium
tuberculosis) 		5 / 12 GLU A 209
GLY A 373
SER A 392
GLY A 104
GLU A 105
 None
 1.10A 3g2oA-1nl3A:
3.8		 3g2oA-1nl3A:
17.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RV5_B_DXCB92_0
(TROPONIN C, SLOW
SKELETAL AND CARDIAC
MUSCLES)		 1nl3 PREPROTEIN
TRANSLOCASE SECA 1
SUBUNIT
(Mycobacterium
tuberculosis) 		4 / 5 VAL A  77
VAL A 145
ARG A 144
LYS A 107
 None
 1.45A 3rv5A-1nl3A:
0.0
3rv5B-1nl3A:
0.0		 3rv5A-1nl3A:
7.94
3rv5B-1nl3A:
7.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SMT_A_ACTA500_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
SETD3)		 1nl3 PREPROTEIN
TRANSLOCASE SECA 1
SUBUNIT
(Mycobacterium
tuberculosis) 		3 / 3 PHE A 594
SER A 625
GLN A 629
 None
 0.96A 3smtA-1nl3A:
0.0		 3smtA-1nl3A:
20.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TWP_D_SALD404_1
(ANTHRANILATE
PHOSPHORIBOSYLTRANSF
ERASE)		 1nl3 PREPROTEIN
TRANSLOCASE SECA 1
SUBUNIT
(Mycobacterium
tuberculosis) 		4 / 5 ALA A 115
PRO A 114
TYR A 116
ALA A  70
 None
 1.23A 3twpD-1nl3A:
1.9		 3twpD-1nl3A:
18.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UZZ_B_ASDB501_1
(3-OXO-5-BETA-STEROID
4-DEHYDROGENASE)		 1nl3 PREPROTEIN
TRANSLOCASE SECA 1
SUBUNIT
(Mycobacterium
tuberculosis) 		4 / 8 TYR A 656
TRP A 779
LEU A 819
MET A 822
 None
 1.18A 3uzzB-1nl3A:
undetectable		 3uzzB-1nl3A:
16.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AF0_A_MOAA1526_1
(INOSINE-5'-MONOPHOSP
HATE DEHYDROGENASE)		 1nl3 PREPROTEIN
TRANSLOCASE SECA 1
SUBUNIT
(Mycobacterium
tuberculosis) 		4 / 8 SER A 285
ASN A 284
ARG A 777
GLY A 828
 None
 0.90A 4af0A-1nl3A:
undetectable		 4af0A-1nl3A:
21.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4B53_B_ACTB1445_0
(IG GAMMA-4 CHAIN C
REGION)		 1nl3 PREPROTEIN
TRANSLOCASE SECA 1
SUBUNIT
(Mycobacterium
tuberculosis) 		3 / 3 GLU A 825
GLY A 821
SER A 289
 None
 0.70A 4b53B-1nl3A:
undetectable		 4b53B-1nl3A:
7.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DC3_A_ADNA401_2
(ADENOSINE KINASE)		 1nl3 PREPROTEIN
TRANSLOCASE SECA 1
SUBUNIT
(Mycobacterium
tuberculosis) 		4 / 4 LEU A 222
ILE A 213
GLY A 182
PHE A 362
 None
 1.10A 4dc3A-1nl3A:
undetectable		 4dc3A-1nl3A:
17.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DXU_A_ACAA711_1
(LACTOTRANSFERRIN)		 1nl3 PREPROTEIN
TRANSLOCASE SECA 1
SUBUNIT
(Mycobacterium
tuberculosis) 		5 / 6 GLY A 480
VAL A 433
PRO A 432
GLY A 548
GLU A 579
 None
 1.39A 4dxuA-1nl3A:
undetectable		 4dxuA-1nl3A:
15.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FIM_A_CELA711_1
(LACTOTRANSFERRIN)		 1nl3 PREPROTEIN
TRANSLOCASE SECA 1
SUBUNIT
(Mycobacterium
tuberculosis) 		5 / 9 GLY A 480
VAL A 433
PRO A 432
GLU A 546
GLY A 548
 None
 1.44A 4fimA-1nl3A:
undetectable		 4fimA-1nl3A:
15.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HTF_A_ACTA303_0
(S-ADENOSYLMETHIONINE
-DEPENDENT
METHYLTRANSFERASE)		 1nl3 PREPROTEIN
TRANSLOCASE SECA 1
SUBUNIT
(Mycobacterium
tuberculosis) 		3 / 3 TYR A 784
HIS A 335
ARG A 329
 None
 0.81A 4htfA-1nl3A:
3.2		 4htfA-1nl3A:
14.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IKI_A_IMNA201_1
(TRANSTHYRETIN)		 1nl3 PREPROTEIN
TRANSLOCASE SECA 1
SUBUNIT
(Mycobacterium
tuberculosis) 		3 / 3 LYS A  42
LEU A  34
ALA A  41
 None
 0.67A 4ikiA-1nl3A:
undetectable		 4ikiA-1nl3A:
9.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KTT_A_SAMA405_1
(S-ADENOSYLMETHIONINE
SYNTHASE ISOFORM
TYPE-2)		 1nl3 PREPROTEIN
TRANSLOCASE SECA 1
SUBUNIT
(Mycobacterium
tuberculosis) 		4 / 8 ALA A 369
ASP A 138
ILE A 127
ILE A 173
 None
 0.75A 4kttB-1nl3A:
undetectable		 4kttB-1nl3A:
18.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KTT_C_SAMC404_1
(S-ADENOSYLMETHIONINE
SYNTHASE ISOFORM
TYPE-2)		 1nl3 PREPROTEIN
TRANSLOCASE SECA 1
SUBUNIT
(Mycobacterium
tuberculosis) 		4 / 8 ALA A 369
ASP A 138
ILE A 127
ILE A 173
 None
 0.75A 4kttD-1nl3A:
undetectable		 4kttD-1nl3A:
18.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NDN_A_SAMA407_1
(S-ADENOSYLMETHIONINE
SYNTHASE ISOFORM
TYPE-2)		 1nl3 PREPROTEIN
TRANSLOCASE SECA 1
SUBUNIT
(Mycobacterium
tuberculosis) 		4 / 8 ALA A 369
ASP A 138
ILE A 127
ILE A 173
 None
 0.78A 4ndnB-1nl3A:
undetectable		 4ndnB-1nl3A:
18.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NDN_C_SAMC405_1
(S-ADENOSYLMETHIONINE
SYNTHASE ISOFORM
TYPE-2)		 1nl3 PREPROTEIN
TRANSLOCASE SECA 1
SUBUNIT
(Mycobacterium
tuberculosis) 		4 / 8 ALA A 369
ASP A 138
ILE A 127
ILE A 173
 None
 0.81A 4ndnD-1nl3A:
undetectable		 4ndnD-1nl3A:
18.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4TWD_H_377H401_1
(CYS-LOOP
LIGAND-GATED ION
CHANNEL)		 1nl3 PREPROTEIN
TRANSLOCASE SECA 1
SUBUNIT
(Mycobacterium
tuberculosis) 		4 / 6 TYR A 235
ASN A 293
GLU A 781
GLU A 785
 None
 1.34A 4twdG-1nl3A:
0.0
4twdH-1nl3A:
1.3		 4twdG-1nl3A:
15.27
4twdH-1nl3A:
15.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4U9U_A_ACTA1502_0
(NA(+)-TRANSLOCATING
NADH-QUINONE
REDUCTASE SUBUNIT F)		 1nl3 PREPROTEIN
TRANSLOCASE SECA 1
SUBUNIT
(Mycobacterium
tuberculosis) 		4 / 5 GLY A 476
ALA A 475
GLY A 480
PRO A 432
 None
 0.93A 4u9uA-1nl3A:
2.2		 4u9uA-1nl3A:
15.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WOZ_B_MN9B401_0
(N-ACETYLNEURAMINATE
LYASE)		 1nl3 PREPROTEIN
TRANSLOCASE SECA 1
SUBUNIT
(Mycobacterium
tuberculosis) 		4 / 6 SER A 193
LEU A 194
ASP A 195
LEU A 663
 None
 0.93A 4wozA-1nl3A:
0.4
4wozB-1nl3A:
0.3		 4wozA-1nl3A:
16.01
4wozB-1nl3A:
16.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZN7_B_DESB600_1
(ESTROGEN RECEPTOR)		 1nl3 PREPROTEIN
TRANSLOCASE SECA 1
SUBUNIT
(Mycobacterium
tuberculosis) 		5 / 11 MET A 648
ARG A 660
HIS A 782
LEU A 783
MET A 786
 None
 0.95A 4zn7B-1nl3A:
0.0		 4zn7B-1nl3A:
13.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5A06_A_SORA1344_0
(ALDOSE-ALDOSE
OXIDOREDUCTASE)		 1nl3 PREPROTEIN
TRANSLOCASE SECA 1
SUBUNIT
(Mycobacterium
tuberculosis) 		4 / 5 GLU A 412
LYS A 415
ASP A 588
GLU A 556
 None
 1.49A 5a06A-1nl3A:
0.0		 5a06A-1nl3A:
18.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DXE_A_ESTA1000_1
(ESTROGEN RECEPTOR)		 1nl3 PREPROTEIN
TRANSLOCASE SECA 1
SUBUNIT
(Mycobacterium
tuberculosis) 		4 / 8 MET A 648
ARG A 660
HIS A 782
LEU A 783
 None
 1.12A 5dxeA-1nl3A:
undetectable		 5dxeA-1nl3A:
13.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IKT_A_TLFA601_0
(PROSTAGLANDIN G/H
SYNTHASE 2)		 1nl3 PREPROTEIN
TRANSLOCASE SECA 1
SUBUNIT
(Mycobacterium
tuberculosis) 		5 / 12 VAL A  -7
VAL A  87
GLY A  89
ALA A  91
LEU A  95
 None
 1.04A 5iktA-1nl3A:
undetectable		 5iktA-1nl3A:
21.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KVA_B_SAMB301_0
(CAFFEOYL-COA
O-METHYLTRANSFERASE)		 1nl3 PREPROTEIN
TRANSLOCASE SECA 1
SUBUNIT
(Mycobacterium
tuberculosis) 		5 / 12 GLY A 230
ILE A 346
ASP A 229
ALA A 228
TYR A 784
 None
 1.14A 5kvaB-1nl3A:
undetectable		 5kvaB-1nl3A:
15.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M67_B_ACTB505_0
(ADENOSYLHOMOCYSTEINA
SE)		 1nl3 PREPROTEIN
TRANSLOCASE SECA 1
SUBUNIT
(Mycobacterium
tuberculosis) 		4 / 4 ASP A 211
ILE A 215
ARG A 638
ARG A 562
 None
 1.02A 5m67B-1nl3A:
1.0		 5m67B-1nl3A:
19.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N0W_B_SAMB501_0
(PEPTIDE
N-METHYLTRANSFERASE)		 1nl3 PREPROTEIN
TRANSLOCASE SECA 1
SUBUNIT
(Mycobacterium
tuberculosis) 		5 / 12 GLY A 370
PHE A 362
TYR A 175
ILE A 173
VAL A 125
 None
 1.08A 5n0wB-1nl3A:
undetectable		 5n0wB-1nl3A:
19.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N4T_B_BEZB306_0
(BETA-LACTAMASE VIM-2)		 1nl3 PREPROTEIN
TRANSLOCASE SECA 1
SUBUNIT
(Mycobacterium
tuberculosis) 		3 / 3 HIS A 558
ASN A 486
ALA A 488
 None
 0.69A 5n4tB-1nl3A:
undetectable		 5n4tB-1nl3A:
15.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5T8S_B_SAMB402_0
(S-ADENOSYLMETHIONINE
SYNTHASE)		 1nl3 PREPROTEIN
TRANSLOCASE SECA 1
SUBUNIT
(Mycobacterium
tuberculosis) 		4 / 8 ALA A 369
ASP A 138
ILE A 127
ILE A 173
 None
 0.76A 5t8sA-1nl3A:
undetectable		 5t8sA-1nl3A:
20.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X80_C_SALC201_1
(UNCHARACTERIZED
HTH-TYPE
TRANSCRIPTIONAL
REGULATOR RV2887)		 1nl3 PREPROTEIN
TRANSLOCASE SECA 1
SUBUNIT
(Mycobacterium
tuberculosis) 		4 / 7 VAL A 474
VAL A 544
PRO A 432
GLY A 479
 None
 1.00A 5x80C-1nl3A:
1.5
5x80D-1nl3A:
1.4		 5x80C-1nl3A:
11.22
5x80D-1nl3A:
11.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CBZ_A_ESTA601_1
(ESTROGEN RECEPTOR)		 1nl3 PREPROTEIN
TRANSLOCASE SECA 1
SUBUNIT
(Mycobacterium
tuberculosis) 		4 / 8 MET A 648
ARG A 660
HIS A 782
LEU A 783
 None
 1.13A 6cbzA-1nl3A:
undetectable		 6cbzA-1nl3A:
6.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FBN_B_SAMB401_0
(S-ADENOSYLMETHIONINE
SYNTHASE ISOFORM
TYPE-2)		 1nl3 PREPROTEIN
TRANSLOCASE SECA 1
SUBUNIT
(Mycobacterium
tuberculosis) 		4 / 7 ALA A 369
ASP A 138
ILE A 127
ILE A 173
 None
 0.79A 6fbnA-1nl3A:
undetectable		 6fbnA-1nl3A:
18.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6N7F_A_RBFA502_0
(PUTATIVE GLUTATHIONE
REDUCTASE (GR))		 1nl3 PREPROTEIN
TRANSLOCASE SECA 1
SUBUNIT
(Mycobacterium
tuberculosis) 		4 / 7 GLY A 230
HIS A 782
GLU A 332
GLY A 333
 None
 0.98A 6n7fA-1nl3A:
0.0		 6n7fA-1nl3A:
6.64