SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1nld'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1X8V_A_ESLA472_1
(CYTOCHROME P450 51)		 1nld FAB1583
(Mus
musculus) 		4 / 6 VAL H  37
LEU H  48
PHE H  63
MET H  82
 None
 1.15A 1x8vA-1nldH:
undetectable		 1x8vA-1nldH:
17.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WA2_B_SAMB1267_1
(NON-STRUCTURAL
PROTEIN 5)		 1nld FAB1583
(Mus
musculus) 		3 / 3 SER H  76
HIS H  35
ASP H  58
 None
 0.75A 2wa2B-1nldH:
undetectable		 2wa2B-1nldH:
20.83
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5MTH_A_ACTA302_0
(ANTIBODY FAB HEAVY
CHAIN)		 1nld FAB1583
(Mus
musculus) 		5 / 5 SER H 112
ALA H 114
PHE H 146
LEU H 170
ASP H 173
 None
 0.79A 5mthA-1nldH:
26.3		 5mthA-1nldH:
64.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6ECF_I_DVAI3010_0
(VLM2
DODECADEPSIPEPTIDE)		 1nld FAB1583
(Mus
musculus) 		3 / 3 PHE H 146
ARG H  87
ALA H 168
 None
 0.96A 6ecfB-1nldH:
undetectable		 6ecfB-1nldH:
20.40