SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1nlf'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C4D_D_DVAD8_0
(GRAMICIDIN A)		 1nlf REGULATORY PROTEIN
REPA
(Escherichia
coli) 		3 / 3 TRP A 223
VAL A 264
TRP A 251
 None
 1.03A 1c4dC-1nlfA:
undetectable
1c4dD-1nlfA:
undetectable		 1c4dC-1nlfA:
9.68
1c4dD-1nlfA:
9.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C4D_D_DVAD8_0
(GRAMICIDIN A)		 1nlf REGULATORY PROTEIN
REPA
(Escherichia
coli) 		3 / 3 TRP A 251
VAL A 264
TRP A 223
 None
 0.98A 1c4dC-1nlfA:
undetectable
1c4dD-1nlfA:
undetectable		 1c4dC-1nlfA:
9.68
1c4dD-1nlfA:
9.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1IWI_A_CAMA418_0
(CYTOCHROME P450-CAM)		 1nlf REGULATORY PROTEIN
REPA
(Escherichia
coli) 		4 / 8 LEU A 212
VAL A 138
ASP A 140
VAL A 175
 None
 0.94A 1iwiA-1nlfA:
0.0		 1iwiA-1nlfA:
24.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KXH_A_ACRA598_2
(ALPHA-AMYLASE)		 1nlf REGULATORY PROTEIN
REPA
(Escherichia
coli) 		3 / 3 TRP A 208
TYR A  22
LEU A  66
 None
 1.09A 1kxhA-1nlfA:
undetectable		 1kxhA-1nlfA:
20.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AQI_B_CHDB5_0
(FERROCHELATASE)		 1nlf REGULATORY PROTEIN
REPA
(Escherichia
coli) 		3 / 3 PRO A  75
LEU A  74
ARG A 134
 None
 0.85A 3aqiB-1nlfA:
undetectable		 3aqiB-1nlfA:
23.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GCS_A_BAXA401_1
(MITOGEN-ACTIVATED
PROTEIN KINASE 14)		 1nlf REGULATORY PROTEIN
REPA
(Escherichia
coli) 		5 / 12 ALA A 130
LEU A 142
LEU A 139
ILE A 174
ILE A 206
 None
 0.94A 3gcsA-1nlfA:
undetectable		 3gcsA-1nlfA:
22.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JB2_A_SAMA1101_1
(STRUCTURAL PROTEIN
VP3)		 1nlf REGULATORY PROTEIN
REPA
(Escherichia
coli) 		3 / 3 GLU A 132
ASP A 169
ASP A 125
 None
 0.62A 3jb2A-1nlfA:
4.8		 3jb2A-1nlfA:
14.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KP6_B_SALB3008_1
(TRANSCRIPTIONAL
REGULATOR TCAR)		 1nlf REGULATORY PROTEIN
REPA
(Escherichia
coli) 		4 / 7 GLU A 150
VAL A 201
VAL A  36
ALA A 180
 None
 1.06A 3kp6B-1nlfA:
0.9		 3kp6B-1nlfA:
19.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3THR_C_C2FC1410_0
(GLYCINE
N-METHYLTRANSFERASE)		 1nlf REGULATORY PROTEIN
REPA
(Escherichia
coli) 		3 / 3 ARG A 144
PRO A  75
PHE A 145
 None
 1.00A 3thrC-1nlfA:
3.2		 3thrC-1nlfA:
22.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U9F_B_CLMB221_0
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 1nlf REGULATORY PROTEIN
REPA
(Escherichia
coli) 		5 / 12 SER A 210
PHE A 236
LEU A 136
VAL A  71
VAL A  23
 None
 1.27A 3u9fB-1nlfA:
0.0
3u9fC-1nlfA:
0.0		 3u9fB-1nlfA:
21.26
3u9fC-1nlfA:
21.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U9F_H_CLMH221_0
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 1nlf REGULATORY PROTEIN
REPA
(Escherichia
coli) 		5 / 12 SER A 210
PHE A 236
LEU A 136
VAL A  71
VAL A  23
 None
 1.18A 3u9fH-1nlfA:
0.1
3u9fI-1nlfA:
0.0		 3u9fH-1nlfA:
21.26
3u9fI-1nlfA:
21.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U9F_J_CLMJ221_0
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 1nlf REGULATORY PROTEIN
REPA
(Escherichia
coli) 		5 / 12 SER A 210
PHE A 236
LEU A 136
VAL A  71
VAL A  23
 None
 1.31A 3u9fJ-1nlfA:
undetectable
3u9fK-1nlfA:
undetectable		 3u9fJ-1nlfA:
21.26
3u9fK-1nlfA:
21.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U9F_K_CLMK221_0
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 1nlf REGULATORY PROTEIN
REPA
(Escherichia
coli) 		5 / 10 SER A 210
PHE A 236
LEU A 136
VAL A  71
VAL A  23
 None
 1.33A 3u9fK-1nlfA:
0.0		 3u9fK-1nlfA:
21.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U9F_R_CLMR221_0
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 1nlf REGULATORY PROTEIN
REPA
(Escherichia
coli) 		5 / 10 SER A 210
PHE A 236
LEU A 136
VAL A  71
VAL A  23
 None
 1.24A 3u9fR-1nlfA:
undetectable		 3u9fR-1nlfA:
21.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V81_C_NVPC901_1
(HIV-1 REVERSE
TRANSCRIPTASE P66
SUBUNIT)		 1nlf REGULATORY PROTEIN
REPA
(Escherichia
coli) 		4 / 8 VAL A 102
VAL A  71
TYR A  73
LEU A  90
 None
 0.96A 3v81C-1nlfA:
undetectable		 3v81C-1nlfA:
16.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PUO_C_NVPC901_1
(HIV-1 REVERSE
TRANSCRIPTASE, P66
SUBUNIT)		 1nlf REGULATORY PROTEIN
REPA
(Escherichia
coli) 		4 / 8 VAL A 102
VAL A  71
TYR A  73
LEU A  90
 None
 0.96A 4puoC-1nlfA:
undetectable		 4puoC-1nlfA:
16.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PWD_C_NVPC901_1
(HIV-1 REVERSE
TRANSCRIPTASE, P66
SUBUNIT)		 1nlf REGULATORY PROTEIN
REPA
(Escherichia
coli) 		4 / 8 VAL A 102
VAL A  71
TYR A  73
LEU A  90
 None
 0.97A 4pwdC-1nlfA:
undetectable		 4pwdC-1nlfA:
16.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OEX_A_CUA602_0
(THIOCYANATE
DEHYDROGENASE)		 1nlf REGULATORY PROTEIN
REPA
(Escherichia
coli) 		3 / 3 LYS A 261
HIS A  93
HIS A 255
 None
 0.85A 5oexA-1nlfA:
0.0		 5oexA-1nlfA:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OEX_B_CUB602_0
(THIOCYANATE
DEHYDROGENASE)		 1nlf REGULATORY PROTEIN
REPA
(Escherichia
coli) 		3 / 3 LYS A 261
HIS A  93
HIS A 255
 None
 0.91A 5oexB-1nlfA:
0.0		 5oexB-1nlfA:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OEX_C_CUC603_0
(THIOCYANATE
DEHYDROGENASE)		 1nlf REGULATORY PROTEIN
REPA
(Escherichia
coli) 		3 / 3 LYS A 261
HIS A  93
HIS A 255
 None
 0.90A 5oexC-1nlfA:
0.0		 5oexC-1nlfA:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OEX_D_CUD603_0
(THIOCYANATE
DEHYDROGENASE)		 1nlf REGULATORY PROTEIN
REPA
(Escherichia
coli) 		3 / 3 LYS A 261
HIS A  93
HIS A 255
 None
 0.89A 5oexD-1nlfA:
0.0		 5oexD-1nlfA:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CZM_D_HISD402_0
(ATP
PHOSPHORIBOSYLTRANSF
ERASE CATALYTIC
SUBUNIT)		 1nlf REGULATORY PROTEIN
REPA
(Escherichia
coli) 		4 / 8 LEU A  50
VAL A  23
VAL A  71
LEU A  24
 None
 0.84A 6czmD-1nlfA:
undetectable
6czmF-1nlfA:
undetectable		 6czmD-1nlfA:
22.99
6czmF-1nlfA:
22.99