SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1nln'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1AXW_A_MTXA732_1
(THYMIDYLATE SYNTHASE)		 1nln ADENAIN
(Human
mastadenovirus
C) 		5 / 12 LEU A 201
LEU A 124
GLY A 123
PHE A 125
ALA A 195
 None
 1.14A 1axwA-1nlnA:
0.7		 1axwA-1nlnA:
20.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2KCE_B_D16B568_1
(THYMIDYLATE SYNTHASE)		 1nln ADENAIN
(Human
mastadenovirus
C) 		5 / 12 LEU A 201
LEU A 124
GLY A 123
PHE A 125
ALA A 195
 None
 1.19A 2kceB-1nlnA:
0.7		 2kceB-1nlnA:
20.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AF3_A_PAUA314_0
(PANTOTHENATE KINASE)		 1nln ADENAIN
(Human
mastadenovirus
C) 		4 / 6 ARG A  94
PHE A  32
PHE A  29
PHE A  58
 None
 1.37A 3af3A-1nlnA:
0.0		 3af3A-1nlnA:
20.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V7P_A_BEZA430_0
(AMIDOHYDROLASE
FAMILY PROTEIN)		 1nln ADENAIN
(Human
mastadenovirus
C) 		4 / 7 GLY A   2
SER A   3
PHE A 185
LEU A 124
 None
 0.79A 3v7pA-1nlnA:
undetectable		 3v7pA-1nlnA:
19.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4W5N_A_IPHA902_0
(PROTEIN ARGONAUTE-2)		 1nln ADENAIN
(Human
mastadenovirus
C) 		4 / 6 LEU A 107
ILE A 105
LEU A  92
GLU A  89
 None
 0.94A 4w5nA-1nlnA:
undetectable		 4w5nA-1nlnA:
12.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MUG_A_VIVA301_1
(ALPHA-TOCOPHEROL
TRANSFER PROTEIN)		 1nln ADENAIN
(Human
mastadenovirus
C) 		3 / 3 SER A  95
SER A  99
PHE A  29
 None
 0.80A 5mugA-1nlnA:
undetectable		 5mugA-1nlnA:
23.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NVP_A_ACAA18_1
(ENVELOPE
GLYCOPROTEIN,GP41)		 1nln ADENAIN
(Human
mastadenovirus
C) 		5 / 12 SER A   4
LYS A   2
LYS A   9
GLU A   7
LEU A 124
 None
 1.20A 5nvpA-1nlnA:
0.0		 5nvpA-1nlnA:
11.17