SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1nlt'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4BVA_B_T3B1314_1
(THIOMORPHOLINE-CARBO
XYLATE DEHYDROGENASE)		 1nlt MITOCHONDRIAL
PROTEIN IMPORT
PROTEIN MAS5
(Saccharomyces
cerevisiae) 		5 / 12 ARG A 131
VAL A 220
HIS A 118
SER A 121
GLU A 126
 None
 1.48A 4bvaB-1nltA:
undetectable		 4bvaB-1nltA:
19.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FGZ_A_CQAA301_0
(PHOSPHOETHANOLAMINE
N-METHYLTRANSFERASE)		 1nlt MITOCHONDRIAL
PROTEIN IMPORT
PROTEIN MAS5
(Saccharomyces
cerevisiae) 		4 / 8 GLY A 151
GLY A 148
LEU A 142
VAL A 209
 None
 0.78A 4fgzA-1nltA:
undetectable		 4fgzA-1nltA:
19.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WWS_B_SAMB501_0
(PUTATIVE
METHYLTRANSFERASE
NSUN6)		 1nlt MITOCHONDRIAL
PROTEIN IMPORT
PROTEIN MAS5
(Saccharomyces
cerevisiae) 		5 / 12 ALA A 239
PRO A 240
GLY A 148
ASP A 246
GLY A 234
 None
 1.25A 5wwsB-1nltA:
undetectable		 5wwsB-1nltA:
20.25