SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1nlu'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C4D_A_DVAA8_0
(GRAMICIDIN A)		 1nlu SEDOLISIN
(Pseudomonas
sp.) 		3 / 3 VAL A 201
TRP A 353
TRP A 347
 None
 1.49A 1c4dA-1nluA:
undetectable
1c4dB-1nluA:
undetectable		 1c4dA-1nluA:
4.39
1c4dB-1nluA:
4.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KYV_D_RBFD504_1
(6,7-DIMETHYL-8-RIBIT
YLLUMAZINE SYNTHASE)		 1nlu SEDOLISIN
(Pseudomonas
sp.) 		5 / 12 ILE A 274
HIS A   8
GLY A  90
LEU A 296
ILE A 292
 None
 1.22A 1kyvC-1nluA:
7.2
1kyvD-1nluA:
7.3		 1kyvC-1nluA:
18.58
1kyvD-1nluA:
18.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KYV_E_RBFE505_1
(6,7-DIMETHYL-8-RIBIT
YLLUMAZINE SYNTHASE)		 1nlu SEDOLISIN
(Pseudomonas
sp.) 		5 / 12 ILE A 274
HIS A   8
GLY A  90
LEU A 296
ILE A 292
 None
 1.17A 1kyvD-1nluA:
7.3
1kyvE-1nluA:
6.9		 1kyvD-1nluA:
18.58
1kyvE-1nluA:
18.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MZ9_D_VDYD1001_3
(CARTILAGE OLIGOMERIC
MATRIX PROTEIN)		 1nlu SEDOLISIN
(Pseudomonas
sp.) 		3 / 3 THR A  41
LEU A  45
LEU A  54
 None
 0.55A 1mz9C-1nluA:
undetectable		 1mz9C-1nluA:
9.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WRK_A_TFPA204_1
(TROPONIN C, SLOW
SKELETAL AND CARDIAC
MUSCLES)		 1nlu SEDOLISIN
(Pseudomonas
sp.) 		5 / 9 PHE A 118
LEU A 134
PHE A 154
SER A 194
LEU A 114
 None
 1.23A 1wrkA-1nluA:
undetectable
1wrkB-1nluA:
undetectable		 1wrkA-1nluA:
11.76
1wrkB-1nluA:
11.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WRK_A_TFPA204_1
(TROPONIN C, SLOW
SKELETAL AND CARDIAC
MUSCLES)		 1nlu SEDOLISIN
(Pseudomonas
sp.) 		5 / 9 PHE A 118
VAL A 132
LEU A 134
PHE A 154
LEU A 114
 None
 1.30A 1wrkA-1nluA:
undetectable
1wrkB-1nluA:
undetectable		 1wrkA-1nluA:
11.76
1wrkB-1nluA:
11.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1X7P_A_SAMA301_0
(RRNA
METHYLTRANSFERASE)		 1nlu SEDOLISIN
(Pseudomonas
sp.) 		5 / 11 THR A 204
GLY A 354
GLY A 352
SER A 168
ALA A 289
 None
 0.93A 1x7pA-1nluA:
2.2
1x7pB-1nluA:
2.3		 1x7pA-1nluA:
22.67
1x7pB-1nluA:
22.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HC4_A_VDXA525_2
(VITAMIN D RECEPTOR)		 1nlu SEDOLISIN
(Pseudomonas
sp.) 		4 / 7 LEU A 100
LEU A  99
ARG A 299
SER A  91
 None
 1.05A 2hc4A-1nluA:
undetectable		 2hc4A-1nluA:
22.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BXO_A_SAMA238_1
(N,N-DIMETHYLTRANSFER
ASE)		 1nlu SEDOLISIN
(Pseudomonas
sp.) 		3 / 3 TYR A 341
GLU A 138
ASP A 151
 None
 0.86A 3bxoA-1nluA:
undetectable		 3bxoA-1nluA:
21.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EKT_B_017B200_2
(PROTEASE)		 1nlu SEDOLISIN
(Pseudomonas
sp.) 		5 / 9 ALA A 289
GLY A 295
ILE A  88
PRO A  10
ALA A 272
 None
 1.09A 3ektB-1nluA:
undetectable		 3ektB-1nluA:
13.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FAL_A_REAA501_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 1nlu SEDOLISIN
(Pseudomonas
sp.) 		5 / 10 ILE A 130
ALA A 121
GLN A 120
VAL A 294
ILE A  88
 None
 1.05A 3falA-1nluA:
undetectable		 3falA-1nluA:
20.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QPS_A_CHDA211_0
(CMER)		 1nlu SEDOLISIN
(Pseudomonas
sp.) 		5 / 10 LEU A 300
ALA A 363
ILE A 358
TRP A 297
PHE A 315
 None
 1.16A 3qpsA-1nluA:
0.0		 3qpsA-1nluA:
14.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T3S_E_9PLE1_1
(CYTOCHROME P450 2A13)		 1nlu SEDOLISIN
(Pseudomonas
sp.) 		4 / 8 ALA A 303
PHE A 315
ASN A 304
PHE A 370
 None
 1.01A 3t3sE-1nluA:
0.0		 3t3sE-1nluA:
19.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VYW_B_SAMB401_0
(MNMC2)		 1nlu SEDOLISIN
(Pseudomonas
sp.) 		5 / 12 GLY A 234
GLY A 172
LEU A 230
ALA A 193
LEU A 259
 None
 1.25A 3vywB-1nluA:
undetectable		 3vywB-1nluA:
19.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WIP_A_ACHA301_0
(ACETYLCHOLINE-BINDIN
G PROTEIN)		 1nlu SEDOLISIN
(Pseudomonas
sp.) 		4 / 7 TYR A 237
THR A 186
TYR A 341
TYR A 187
 None
 1.46A 3wipA-1nluA:
undetectable
3wipB-1nluA:
undetectable		 3wipA-1nluA:
20.21
3wipB-1nluA:
20.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WIP_B_ACHB301_0
(ACETYLCHOLINE-BINDIN
G PROTEIN)		 1nlu SEDOLISIN
(Pseudomonas
sp.) 		4 / 8 TYR A 237
THR A 186
TYR A 341
TYR A 187
 None
 1.47A 3wipB-1nluA:
undetectable
3wipC-1nluA:
undetectable		 3wipB-1nluA:
20.21
3wipC-1nluA:
20.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WIP_F_ACHF301_0
(ACETYLCHOLINE-BINDIN
G PROTEIN)		 1nlu SEDOLISIN
(Pseudomonas
sp.) 		4 / 7 TYR A 237
THR A 186
TYR A 341
TYR A 187
 None
 1.44A 3wipF-1nluA:
undetectable
3wipG-1nluA:
undetectable		 3wipF-1nluA:
20.21
3wipG-1nluA:
20.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FEV_D_KAND301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 1nlu SEDOLISIN
(Pseudomonas
sp.) 		4 / 7 ASP A 151
ASP A 261
ASN A 197
GLU A 241
 None
 1.21A 4fevD-1nluA:
undetectable		 4fevD-1nluA:
23.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FEV_F_KANF301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 1nlu SEDOLISIN
(Pseudomonas
sp.) 		4 / 7 ASP A 151
ASP A 261
ASN A 197
GLU A 241
 None
 1.21A 4fevF-1nluA:
undetectable		 4fevF-1nluA:
23.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4GKH_B_KANB301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 1nlu SEDOLISIN
(Pseudomonas
sp.) 		4 / 8 ASP A 151
ASP A 261
ASN A 197
GLU A 241
 None
 1.21A 4gkhB-1nluA:
undetectable		 4gkhB-1nluA:
23.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4GKH_G_KANG301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 1nlu SEDOLISIN
(Pseudomonas
sp.) 		4 / 7 ASP A 151
ASP A 261
ASN A 197
GLU A 241
 None
 1.23A 4gkhG-1nluA:
undetectable		 4gkhG-1nluA:
23.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4GKH_J_KANJ301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 1nlu SEDOLISIN
(Pseudomonas
sp.) 		4 / 6 ASP A 151
ASP A 261
ASN A 197
GLU A 241
 None
 1.27A 4gkhJ-1nluA:
0.0		 4gkhJ-1nluA:
23.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UMJ_A_BFQA1297_1
(GERANYLTRANSTRANSFER
ASE)		 1nlu SEDOLISIN
(Pseudomonas
sp.) 		4 / 8 SER A 324
LEU A 325
ASP A 357
ASP A  18
 None
 0.96A 4umjA-1nluA:
undetectable		 4umjA-1nluA:
22.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ESL_A_1YNA701_1
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 1nlu SEDOLISIN
(Pseudomonas
sp.) 		5 / 12 GLY A 135
PHE A  13
ILE A  16
TYR A  17
GLY A 271
 None
 1.19A 5eslA-1nluA:
undetectable		 5eslA-1nluA:
21.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HIK_A_SAMA301_0
(GLYCINE SARCOSINE
N-METHYLTRANSFERASE)		 1nlu SEDOLISIN
(Pseudomonas
sp.) 		5 / 12 GLY A 203
GLY A 354
SER A 355
GLY A 169
SER A 168
 None
 1.25A 5hikA-1nluA:
2.4		 5hikA-1nluA:
21.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IGJ_A_CTYA402_2
(MACROLIDE
2'-PHOSPHOTRANSFERAS
E)		 1nlu SEDOLISIN
(Pseudomonas
sp.) 		4 / 5 PRO A 260
LEU A 361
TYR A  17
PHE A  13
 None
 1.43A 5igjA-1nluA:
undetectable		 5igjA-1nluA:
22.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TUD_D_ERMD1201_2
(5-HYDROXYTRYPTAMINE
RECEPTOR 2B,SOLUBLE
CYTOCHROME B562
CHIMERA)		 1nlu SEDOLISIN
(Pseudomonas
sp.) 		4 / 6 LEU A  54
VAL A  57
THR A  59
LEU A 296
 None
 0.92A 5tudD-1nluA:
undetectable		 5tudD-1nluA:
19.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X7F_A_SAMA301_0
(PUTATIVE
O-METHYLTRANSFERASE
RV1220C)		 1nlu SEDOLISIN
(Pseudomonas
sp.) 		5 / 12 GLY A 295
GLY A  94
GLY A  90
ALA A  55
ALA A  95
 None
 0.97A 5x7fA-1nluA:
undetectable		 5x7fA-1nluA:
21.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EBP_A_DAHA123_0
(RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE,
BETA SUBUNIT)		 1nlu SEDOLISIN
(Pseudomonas
sp.) 		5 / 9 LEU A 206
THR A 204
GLY A 354
PHE A  13
ILE A 292
 None
 1.25A 6ebpA-1nluA:
0.0		 6ebpA-1nluA:
13.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EXI_A_ADNA502_1
(ADENOSYLHOMOCYSTEINA
SE)		 1nlu SEDOLISIN
(Pseudomonas
sp.) 		3 / 3 LEU A 356
ASN A 368
LEU A 308
 None
 0.69A 6exiA-1nluA:
undetectable		 6exiA-1nluA:
12.26