SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1nlx'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EYZ_A_CCSA109_0
(CELLULOSOME-RELATED
PROTEIN MODULE FROM
RUMINOCOCCUS
FLAVEFACIENS THAT
RESEMBLES
PAPAIN-LIKE CYSTEINE
PEPTIDASES)		 1nlx POLLEN ALLERGEN PHL
P 6
(Phleum
pratense) 		4 / 8 PHE A 491
VAL A 467
ILE A 498
SER A 492
 None
 1.00A 4eyzA-1nlxA:
undetectable		 4eyzA-1nlxA:
18.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EYZ_B_CCSB109_0
(CELLULOSOME-RELATED
PROTEIN MODULE FROM
RUMINOCOCCUS
FLAVEFACIENS THAT
RESEMBLES
PAPAIN-LIKE CYSTEINE
PEPTIDASES)		 1nlx POLLEN ALLERGEN PHL
P 6
(Phleum
pratense) 		4 / 8 PHE A 491
VAL A 467
ILE A 498
SER A 492
 None
 1.00A 4eyzB-1nlxA:
undetectable		 4eyzB-1nlxA:
18.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5E5J_A_017A201_3
(PROTEASE)		 1nlx POLLEN ALLERGEN PHL
P 6
(Phleum
pratense) 		3 / 3 ASP A 452
VAL A 415
LEU A 464
 None
 0.67A 5e5jB-1nlxA:
undetectable		 5e5jB-1nlxA:
18.97