SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1nm3'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1H4O_A_BEZA1162_0
(PEROXIREDOXIN 5)		 1nm3 PROTEIN HI0572
(Haemophilus
influenzae) 		5 / 10 PRO A  42
CYH A  49
LEU A 118
ARG A 126
GLY A 147
 None
 1.30A 1h4oA-1nm3A:
24.1
1h4oB-1nm3A:
24.3		 1h4oA-1nm3A:
32.12
1h4oB-1nm3A:
32.12
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1H4O_A_BEZA1162_0
(PEROXIREDOXIN 5)		 1nm3 PROTEIN HI0572
(Haemophilus
influenzae) 		7 / 10 PRO A  42
THR A  46
PRO A  47
CYH A  49
LEU A 118
PHE A 120
ARG A 126
 None
 0.81A 1h4oA-1nm3A:
24.1
1h4oB-1nm3A:
24.3		 1h4oA-1nm3A:
32.12
1h4oB-1nm3A:
32.12
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1H4O_B_BEZB1162_0
(PEROXIREDOXIN 5)		 1nm3 PROTEIN HI0572
(Haemophilus
influenzae) 		6 / 8 PRO A  42
THR A  46
PRO A  47
CYH A  49
PHE A 120
ARG A 126
 None
 0.58A 1h4oB-1nm3A:
24.3		 1h4oB-1nm3A:
32.12
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1H4O_C_BEZC1162_0
(PEROXIREDOXIN 5)		 1nm3 PROTEIN HI0572
(Haemophilus
influenzae) 		6 / 9 PRO A  42
THR A  46
PRO A  47
CYH A  49
PHE A 120
ARG A 126
 None
 0.60A 1h4oC-1nm3A:
24.1
1h4oD-1nm3A:
24.0		 1h4oC-1nm3A:
32.12
1h4oD-1nm3A:
32.12
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1H4O_D_BEZD1162_0
(PEROXIREDOXIN 5)		 1nm3 PROTEIN HI0572
(Haemophilus
influenzae) 		7 / 9 PRO A  42
THR A  46
PRO A  47
CYH A  49
LEU A 118
PHE A 120
ARG A 126
 None
 0.81A 1h4oD-1nm3A:
24.0		 1h4oD-1nm3A:
32.12
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1H4O_E_BEZE1162_0
(PEROXIREDOXIN 5)		 1nm3 PROTEIN HI0572
(Haemophilus
influenzae) 		6 / 9 PRO A  42
THR A  46
PRO A  47
CYH A  49
PHE A 120
ARG A 126
 None
 0.59A 1h4oE-1nm3A:
24.0
1h4oF-1nm3A:
24.1		 1h4oE-1nm3A:
32.12
1h4oF-1nm3A:
32.12
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1H4O_F_BEZF1162_0
(PEROXIREDOXIN 5)		 1nm3 PROTEIN HI0572
(Haemophilus
influenzae) 		7 / 9 PRO A  42
THR A  46
PRO A  47
CYH A  49
LEU A 118
PHE A 120
ARG A 126
 None
 0.81A 1h4oF-1nm3A:
24.1		 1h4oF-1nm3A:
32.12
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1H4O_G_BEZG1162_0
(PEROXIREDOXIN 5)		 1nm3 PROTEIN HI0572
(Haemophilus
influenzae) 		7 / 8 PRO A  42
THR A  46
PRO A  47
CYH A  49
LEU A 118
PHE A 120
ARG A 126
 None
 0.79A 1h4oG-1nm3A:
24.1		 1h4oG-1nm3A:
32.12
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1H4O_H_BEZH1162_0
(PEROXIREDOXIN 5)		 1nm3 PROTEIN HI0572
(Haemophilus
influenzae) 		7 / 9 PRO A  42
THR A  46
PRO A  47
CYH A  49
LEU A 118
PHE A 120
ARG A 126
 None
 0.84A 1h4oH-1nm3A:
24.3		 1h4oH-1nm3A:
32.12
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1HD2_A_BEZA201_0
(PEROXIREDOXIN 5
RESIDUES 54-214)		 1nm3 PROTEIN HI0572
(Haemophilus
influenzae) 		7 / 9 PRO A  42
THR A  46
PRO A  47
CYH A  49
LEU A 118
PHE A 120
ARG A 126
 None
 0.85A 1hd2A-1nm3A:
23.8		 1hd2A-1nm3A:
32.12
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1OC3_A_BEZA201_0
(PEROXIREDOXIN 5)		 1nm3 PROTEIN HI0572
(Haemophilus
influenzae) 		6 / 8 PRO A  42
THR A  46
PRO A  47
CYH A  49
PHE A 120
ARG A 126
 None
 0.61A 1oc3A-1nm3A:
24.0		 1oc3A-1nm3A:
31.86
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1OC3_B_BEZB201_0
(PEROXIREDOXIN 5)		 1nm3 PROTEIN HI0572
(Haemophilus
influenzae) 		7 / 9 PRO A  42
THR A  46
PRO A  47
CYH A  49
LEU A 118
PHE A 120
ARG A 126
 None
 0.82A 1oc3B-1nm3A:
24.2		 1oc3B-1nm3A:
31.86
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1URM_A_BEZA201_0
(PEROXIREDOXIN 5)		 1nm3 PROTEIN HI0572
(Haemophilus
influenzae) 		6 / 9 PRO A  42
THR A  46
PRO A  47
LEU A 118
PHE A 120
ARG A 126
 None
 0.89A 1urmA-1nm3A:
23.1		 1urmA-1nm3A:
31.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V32_C_BEZC1222_0
(PEROXIREDOXIN 6)		 1nm3 PROTEIN HI0572
(Haemophilus
influenzae) 		4 / 8 PRO A  42
THR A  46
PRO A  47
ARG A 126
 None
 0.72A 2v32C-1nm3A:
16.4
2v32D-1nm3A:
18.0		 2v32C-1nm3A:
26.34
2v32D-1nm3A:
26.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V41_C_BEZC1218_0
(PEROXIREDOXIN 6.)		 1nm3 PROTEIN HI0572
(Haemophilus
influenzae) 		4 / 8 PRO A  42
THR A  46
PRO A  47
ARG A 126
 None
 0.69A 2v41C-1nm3A:
16.9
2v41D-1nm3A:
18.2		 2v41C-1nm3A:
26.34
2v41D-1nm3A:
26.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V41_D_BEZD1222_0
(PEROXIREDOXIN 6.)		 1nm3 PROTEIN HI0572
(Haemophilus
influenzae) 		4 / 8 PRO A  42
THR A  46
PRO A  47
ARG A 126
 None
 0.77A 2v41C-1nm3A:
16.9
2v41D-1nm3A:
18.2		 2v41C-1nm3A:
26.34
2v41D-1nm3A:
26.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V41_H_BEZH1222_0
(PEROXIREDOXIN 6.)		 1nm3 PROTEIN HI0572
(Haemophilus
influenzae) 		4 / 8 PRO A  42
THR A  46
PRO A  47
ARG A 126
 None
 0.73A 2v41G-1nm3A:
16.2
2v41H-1nm3A:
16.3		 2v41G-1nm3A:
26.34
2v41H-1nm3A:
26.34
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2VL2_A_BEZA1162_0
(PEROXIREDOXIN-5)		 1nm3 PROTEIN HI0572
(Haemophilus
influenzae) 		7 / 10 PRO A  42
THR A  46
PRO A  47
CYH A  49
LEU A 118
PHE A 120
ARG A 126
 None
 0.82A 2vl2A-1nm3A:
24.1
2vl2C-1nm3A:
20.6		 2vl2A-1nm3A:
31.86
2vl2C-1nm3A:
31.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RFA_B_SAMB406_0
(RIBOSOMAL RNA LARGE
SUBUNIT
METHYLTRANSFERASE N)		 1nm3 PROTEIN HI0572
(Haemophilus
influenzae) 		5 / 12 MET A 111
SER A 124
SER A  76
SER A  40
VAL A  38
 None
 1.48A 3rfaB-1nm3A:
undetectable		 3rfaB-1nm3A:
22.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U9F_J_CLMJ221_0
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 1nm3 PROTEIN HI0572
(Haemophilus
influenzae) 		5 / 12 SER A 124
PHE A 105
LEU A  73
VAL A  36
PHE A  31
 None
 1.35A 3u9fJ-1nm3A:
undetectable
3u9fK-1nm3A:
undetectable		 3u9fJ-1nm3A:
24.12
3u9fK-1nm3A:
24.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ACA_C_DXCC1476_0
(TRANSLATION
ELONGATION FACTOR
SELB)		 1nm3 PROTEIN HI0572
(Haemophilus
influenzae) 		4 / 5 ILE A  37
ALA A  61
HIS A  53
ARG A  56
 None
 1.08A 4acaB-1nm3A:
undetectable
4acaC-1nm3A:
undetectable		 4acaB-1nm3A:
20.54
4acaC-1nm3A:
20.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FU9_A_ACTA311_0
(UROKINASE-TYPE
PLASMINOGEN
ACTIVATOR)		 1nm3 PROTEIN HI0572
(Haemophilus
influenzae) 		3 / 3 GLN A 222
THR A 219
THR A 218
 None
 0.83A 4fu9A-1nm3A:
0.0		 4fu9A-1nm3A:
22.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LNW_A_T3A502_1
(THYROID HORMONE
RECEPTOR ALPHA)		 1nm3 PROTEIN HI0572
(Haemophilus
influenzae) 		4 / 8 SER A 196
GLN A 169
MET A 158
ARG A  56
 None
 1.14A 4lnwA-1nm3A:
undetectable		 4lnwA-1nm3A:
19.43