SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1nmw'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1EI6_D_PPFD412_1 (PHOSPHONOACETATE HYDROLASE)	1nmw	PEPTIDYL-PROLYL CIS-TRANS ISOMERASE NIMA-INTERACTING 1 (Homo sapiens)	4 / 8	PHE A 151 THR A 152 ILE A 156 HIS A 59	None	0.93A	1ei6D-1nmwA: undetectable	1ei6D-1nmwA: 14.77
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4TNS_A_REAA201_1 (PEPTIDYL-PROLYL CIS-TRANS ISOMERASE NIMA-INTERACTING 1)	1nmw	PEPTIDYL-PROLYL CIS-TRANS ISOMERASE NIMA-INTERACTING 1 (Homo sapiens)	5 / 9	HIS A 59 LYS A 63 MET A 130 PHE A 134 SER A 154	None SO4 A 200 (-3.1A) None None SO4 A 200 (-4.1A)	0.93A	4tnsA-1nmwA: 20.2	4tnsA-1nmwA: 98.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5M8R_B_MMSB514_1 (5,6-DIHYDROXYINDOLE- 2-CARBOXYLIC ACID OXIDASE)	1nmw	PEPTIDYL-PROLYL CIS-TRANS ISOMERASE NIMA-INTERACTING 1 (Homo sapiens)	4 / 8	SER A 147 HIS A 59 HIS A 157 VAL A 62	None	0.95A	5m8rB-1nmwA: undetectable	5m8rB-1nmwA: 14.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5M8R_D_MMSD509_1 (5,6-DIHYDROXYINDOLE- 2-CARBOXYLIC ACID OXIDASE)	1nmw	PEPTIDYL-PROLYL CIS-TRANS ISOMERASE NIMA-INTERACTING 1 (Homo sapiens)	4 / 8	SER A 147 HIS A 59 HIS A 157 VAL A 62	None	0.96A	5m8rD-1nmwA: undetectable	5m8rD-1nmwA: 14.05

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1EI6_D_PPFD412_1","PHOSPHONOACETATE HYDROLASE","1nmw","PEPTIDYL-PROLYL CIS-TRANS ISOMERASE NIMA-INTERACTING 1","Homo sapiens",4,"PHE A 151;THR A 152;ILE A 156;HIS A  59","None","0.93A","1ei6D-1nmwA:undetectable","1ei6D-1nmwA:14.77"],["4TNS_A_REAA201_1","PEPTIDYL-PROLYL CIS-TRANS ISOMERASE NIMA-INTERACTING 1","1nmw","PEPTIDYL-PROLYL CIS-TRANS ISOMERASE NIMA-INTERACTING 1","Homo sapiens",5,"HIS A  59;LYS A  63;MET A 130;PHE A 134;SER A 154","None;SO4 A 200 (-3.1A);None;None;SO4 A 200 (-4.1A)","0.93A","4tnsA-1nmwA:20.2","4tnsA-1nmwA:98.25"],["5M8R_B_MMSB514_1","5,6-DIHYDROXYINDOLE-2-CARBOXYLIC ACID OXIDASE","1nmw","PEPTIDYL-PROLYL CIS-TRANS ISOMERASE NIMA-INTERACTING 1","Homo sapiens",4,"SER A 147;HIS A  59;HIS A 157;VAL A  62","None","0.95A","5m8rB-1nmwA:undetectable","5m8rB-1nmwA:14.05"],["5M8R_D_MMSD509_1","5,6-DIHYDROXYINDOLE-2-CARBOXYLIC ACID OXIDASE","1nmw","PEPTIDYL-PROLYL CIS-TRANS ISOMERASE NIMA-INTERACTING 1","Homo sapiens",4,"SER A 147;HIS A  59;HIS A 157;VAL A  62","None","0.96A","5m8rD-1nmwA:undetectable","5m8rD-1nmwA:14.05"]]