SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1nmy'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1CD2_A_FOLA307_1
(DIHYDROFOLATE
REDUCTASE)		 1nmy SIMILAR TO
THYMIDYLATE KINASE
(DTMP KINASE)
(Homo
sapiens) 		3 / 3 GLU A 185
ILE A 184
ARG A  24
 None
ANP  A 303 ( 4.6A)
ADP  A 302 ( 4.9A)
 0.79A 1cd2A-1nmyA:
0.7		 1cd2A-1nmyA:
22.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DTT_B_H4BB1001_1
(HYPOTHETICAL PROTEIN
PH0634)		 1nmy SIMILAR TO
THYMIDYLATE KINASE
(DTMP KINASE)
(Homo
sapiens) 		5 / 10 GLU A 196
HIS A  35
THR A 201
THR A 203
GLU A 204
 None
 1.13A 2dttA-1nmyA:
0.0
2dttB-1nmyA:
0.0		 2dttA-1nmyA:
19.52
2dttB-1nmyA:
19.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A99_D_MIYD392_1
(TETX2 PROTEIN)		 1nmy SIMILAR TO
THYMIDYLATE KINASE
(DTMP KINASE)
(Homo
sapiens) 		4 / 5 HIS A 188
GLN A  22
SER A  23
VAL A  94
 None
 1.42A 4a99D-1nmyA:
0.0		 4a99D-1nmyA:
19.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4G1Q_A_T27A601_1
(REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H)		 1nmy SIMILAR TO
THYMIDYLATE KINASE
(DTMP KINASE)
(Homo
sapiens) 		5 / 12 PRO A 127
LEU A 210
LYS A 118
VAL A 103
PRO A 120
 None
 1.27A 4g1qA-1nmyA:
undetectable		 4g1qA-1nmyA:
17.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ID5_A_T27A601_1
(REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H)		 1nmy SIMILAR TO
THYMIDYLATE KINASE
(DTMP KINASE)
(Homo
sapiens) 		5 / 12 PRO A 127
LEU A 210
LYS A 118
VAL A 103
PRO A 120
 None
 1.30A 4id5A-1nmyA:
undetectable		 4id5A-1nmyA:
17.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IFV_A_T27A601_1
(EXORIBONUCLEASE H,
P66 RT)		 1nmy SIMILAR TO
THYMIDYLATE KINASE
(DTMP KINASE)
(Homo
sapiens) 		5 / 12 PRO A 127
LEU A 210
LYS A 118
VAL A 103
PRO A 120
 None
 1.30A 4ifvA-1nmyA:
0.0		 4ifvA-1nmyA:
17.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IFY_A_T27A601_1
(REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H)		 1nmy SIMILAR TO
THYMIDYLATE KINASE
(DTMP KINASE)
(Homo
sapiens) 		5 / 12 PRO A 127
LEU A 210
LYS A 118
VAL A 103
PRO A 120
 None
 1.28A 4ifyA-1nmyA:
undetectable		 4ifyA-1nmyA:
17.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IG3_A_T27A601_1
(REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H)		 1nmy SIMILAR TO
THYMIDYLATE KINASE
(DTMP KINASE)
(Homo
sapiens) 		5 / 12 PRO A 127
LEU A 210
LYS A 118
VAL A 103
PRO A 120
 None
 1.26A 4ig3A-1nmyA:
undetectable		 4ig3A-1nmyA:
17.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KFB_A_T27A607_1
(REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H,
EXORIBONUCLEA P66 RT)		 1nmy SIMILAR TO
THYMIDYLATE KINASE
(DTMP KINASE)
(Homo
sapiens) 		5 / 12 PRO A 127
LEU A 210
LYS A 118
VAL A 103
PRO A 120
 None
 1.33A 4kfbA-1nmyA:
undetectable		 4kfbA-1nmyA:
17.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XI3_A_29SA601_1
(ESTROGEN RECEPTOR)		 1nmy SIMILAR TO
THYMIDYLATE KINASE
(DTMP KINASE)
(Homo
sapiens) 		5 / 12 THR A 201
ALA A 198
ASP A 197
LEU A 194
LEU A   8
 None
 1.23A 4xi3A-1nmyA:
undetectable		 4xi3A-1nmyA:
21.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B0I_B_TA1B502_1
(TUBULIN BETA CHAIN)		 1nmy SIMILAR TO
THYMIDYLATE KINASE
(DTMP KINASE)
(Homo
sapiens) 		5 / 12 VAL A  95
ASP A  96
ASP A 121
LEU A 210
GLY A  13
 None
MG  A 401 ( 4.1A)
None
None
None
 1.05A 6b0iB-1nmyA:
undetectable		 6b0iB-1nmyA:
19.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B0L_B_TA1B502_1
(TUBULIN BETA CHAIN)		 1nmy SIMILAR TO
THYMIDYLATE KINASE
(DTMP KINASE)
(Homo
sapiens) 		5 / 12 VAL A  95
ASP A  96
ASP A 121
LEU A 210
GLY A  13
 None
MG  A 401 ( 4.1A)
None
None
None
 1.12A 6b0lB-1nmyA:
undetectable		 6b0lB-1nmyA:
19.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6ECF_I_DVAI3010_0
(VLM2
DODECADEPSIPEPTIDE)		 1nmy SIMILAR TO
THYMIDYLATE KINASE
(DTMP KINASE)
(Homo
sapiens) 		3 / 3 PHE A 164
ARG A  97
ALA A  17
 None
FDM  A 301 ( 3.4A)
ADP  A 302 ( 4.4A)
 0.88A 6ecfB-1nmyA:
2.1		 6ecfB-1nmyA:
22.83