SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1nnh'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1I9G_A_SAMA301_1
(HYPOTHETICAL PROTEIN
RV2118C)		 1nnh ASPARAGINYL-TRNA
SYNTHETASE-RELATED
PEPTIDE
(Pyrococcus
furiosus) 		3 / 3 GLU A 101
HIS A 110
ASP A  52
 None
 0.79A 1i9gA-1nnhA:
undetectable		 1i9gA-1nnhA:
21.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JR1_A_MOAA1332_1
(INOSINE-5'-MONOPHOSP
HATE DEHYDROGENASE 2)		 1nnh ASPARAGINYL-TRNA
SYNTHETASE-RELATED
PEPTIDE
(Pyrococcus
furiosus) 		5 / 11 ASP A  47
ASN A  97
ARG A  99
GLY A 264
GLY A 219
 None
 1.37A 1jr1A-1nnhA:
undetectable		 1jr1A-1nnhA:
21.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MRJ_A_ADNA300_1
(ALPHA-TRICHOSANTHIN)		 1nnh ASPARAGINYL-TRNA
SYNTHETASE-RELATED
PEPTIDE
(Pyrococcus
furiosus) 		4 / 8 ILE A  77
GLY A 219
SER A  75
ARG A  99
 None
 0.86A 1mrjA-1nnhA:
undetectable		 1mrjA-1nnhA:
19.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EJG_B_ADNB1502_1
(235AA LONG
HYPOTHETICAL
BIOTIN--[ACETYL-COA-
CARBOXYLASE] LIGASE)		 1nnh ASPARAGINYL-TRNA
SYNTHETASE-RELATED
PEPTIDE
(Pyrococcus
furiosus) 		4 / 7 TRP A 202
LYS A 232
PRO A  51
ALA A 236
 None
 1.32A 2ejgB-1nnhA:
4.0		 2ejgB-1nnhA:
22.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QMJ_A_ACRA1001_1
(MALTASE-GLUCOAMYLASE
, INTESTINAL)		 1nnh ASPARAGINYL-TRNA
SYNTHETASE-RELATED
PEPTIDE
(Pyrococcus
furiosus) 		5 / 12 ASP A 173
ILE A 208
ILE A 186
ARG A 191
ASP A  52
 None
 1.21A 2qmjA-1nnhA:
undetectable		 2qmjA-1nnhA:
16.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QQC_A_AG2A671_1
(PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE (EC
4.1.1.19) (PVLARGDC))		 1nnh ASPARAGINYL-TRNA
SYNTHETASE-RELATED
PEPTIDE
(Pyrococcus
furiosus) 		4 / 7 ILE A  45
GLN A  81
LEU A 255
LEU A 247
 None
 0.88A 2qqcB-1nnhA:
0.2
2qqcC-1nnhA:
undetectable		 2qqcB-1nnhA:
16.96
2qqcC-1nnhA:
12.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QQC_A_AG2A672_1
(PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE (EC
4.1.1.19) (PVLARGDC))		 1nnh ASPARAGINYL-TRNA
SYNTHETASE-RELATED
PEPTIDE
(Pyrococcus
furiosus) 		4 / 7 LEU A 255
LEU A 247
ILE A  45
GLN A  81
 None
 0.89A 2qqcA-1nnhA:
undetectable
2qqcF-1nnhA:
0.0		 2qqcA-1nnhA:
12.85
2qqcF-1nnhA:
16.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QQC_E_AG2E671_1
(PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE (EC
4.1.1.19) (PVLARGDC))		 1nnh ASPARAGINYL-TRNA
SYNTHETASE-RELATED
PEPTIDE
(Pyrococcus
furiosus) 		4 / 7 ILE A  45
GLN A  81
LEU A 255
LEU A 247
 None
 0.87A 2qqcD-1nnhA:
0.0
2qqcE-1nnhA:
undetectable		 2qqcD-1nnhA:
16.96
2qqcE-1nnhA:
12.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QQC_I_AG2I671_1
(PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE (EC
4.1.1.19) (PVLARGDC))		 1nnh ASPARAGINYL-TRNA
SYNTHETASE-RELATED
PEPTIDE
(Pyrococcus
furiosus) 		4 / 7 LEU A 255
LEU A 247
ILE A  45
GLN A  81
 None
 0.91A 2qqcG-1nnhA:
undetectable
2qqcJ-1nnhA:
0.2		 2qqcG-1nnhA:
12.85
2qqcJ-1nnhA:
16.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QQC_I_AG2I672_1
(PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE (EC
4.1.1.19) (PVLARGDC))		 1nnh ASPARAGINYL-TRNA
SYNTHETASE-RELATED
PEPTIDE
(Pyrococcus
furiosus) 		4 / 7 LEU A 255
LEU A 247
ILE A  45
GLN A  81
 None
 0.87A 2qqcI-1nnhA:
undetectable
2qqcL-1nnhA:
0.2		 2qqcI-1nnhA:
12.85
2qqcL-1nnhA:
16.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QQC_K_AG2K671_1
(PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE (EC
4.1.1.19) (PVLARGDC))		 1nnh ASPARAGINYL-TRNA
SYNTHETASE-RELATED
PEPTIDE
(Pyrococcus
furiosus) 		4 / 8 ILE A  45
GLN A  81
LEU A 255
LEU A 247
 None
 0.89A 2qqcH-1nnhA:
0.2
2qqcK-1nnhA:
undetectable		 2qqcH-1nnhA:
16.96
2qqcK-1nnhA:
12.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CKZ_A_ZMRA469_2
(NEURAMINIDASE)		 1nnh ASPARAGINYL-TRNA
SYNTHETASE-RELATED
PEPTIDE
(Pyrococcus
furiosus) 		4 / 6 ASP A  47
ARG A  99
ARG A  71
SER A 242
 None
 1.45A 3ckzA-1nnhA:
undetectable		 3ckzA-1nnhA:
21.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3E23_A_SAMA221_1
(UNCHARACTERIZED
PROTEIN RPA2492)		 1nnh ASPARAGINYL-TRNA
SYNTHETASE-RELATED
PEPTIDE
(Pyrococcus
furiosus) 		3 / 3 TYR A 194
ASP A 118
HIS A  74
 None
 0.92A 3e23A-1nnhA:
undetectable		 3e23A-1nnhA:
20.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MJR_D_AC2D601_1
(DEOXYCYTIDINE KINASE)		 1nnh ASPARAGINYL-TRNA
SYNTHETASE-RELATED
PEPTIDE
(Pyrococcus
furiosus) 		4 / 8 GLU A 145
TYR A 211
PHE A 271
ARG A 142
 None
 0.99A 3mjrD-1nnhA:
undetectable		 3mjrD-1nnhA:
20.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PHA_A_ACRA701_1
(ALPHA-GLUCOSIDASE)		 1nnh ASPARAGINYL-TRNA
SYNTHETASE-RELATED
PEPTIDE
(Pyrococcus
furiosus) 		5 / 12 ASP A 173
ILE A 208
ILE A 186
ARG A 191
ASP A  52
 None
 1.19A 3phaA-1nnhA:
undetectable		 3phaA-1nnhA:
19.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PHA_A_ACRA701_1
(ALPHA-GLUCOSIDASE)		 1nnh ASPARAGINYL-TRNA
SYNTHETASE-RELATED
PEPTIDE
(Pyrococcus
furiosus) 		5 / 12 ASP A 173
ILE A 208
ILE A 186
ASP A 206
ASP A  52
 None
 1.35A 3phaA-1nnhA:
undetectable		 3phaA-1nnhA:
19.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PHA_B_ACRB701_1
(ALPHA-GLUCOSIDASE)		 1nnh ASPARAGINYL-TRNA
SYNTHETASE-RELATED
PEPTIDE
(Pyrococcus
furiosus) 		6 / 12 ASP A 173
ILE A 208
ILE A 186
ASP A 206
ARG A 191
ASP A  52
 None
 1.41A 3phaB-1nnhA:
undetectable		 3phaB-1nnhA:
19.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3POC_B_ACRB664_1
(ALPHA-GLUCOSIDASE)		 1nnh ASPARAGINYL-TRNA
SYNTHETASE-RELATED
PEPTIDE
(Pyrococcus
furiosus) 		5 / 12 ASP A 173
ILE A 208
ILE A 186
ARG A 191
ASP A  52
 None
 1.23A 3pocB-1nnhA:
undetectable		 3pocB-1nnhA:
19.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W68_A_VIVA301_0
(ALPHA-TOCOPHEROL
TRANSFER PROTEIN)		 1nnh ASPARAGINYL-TRNA
SYNTHETASE-RELATED
PEPTIDE
(Pyrococcus
furiosus) 		5 / 12 LEU A  94
ILE A  21
VAL A 265
LEU A 268
VAL A 216
 None
 1.19A 3w68A-1nnhA:
undetectable		 3w68A-1nnhA:
24.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W68_C_VIVC301_0
(ALPHA-TOCOPHEROL
TRANSFER PROTEIN)		 1nnh ASPARAGINYL-TRNA
SYNTHETASE-RELATED
PEPTIDE
(Pyrococcus
furiosus) 		5 / 12 LEU A  94
ILE A  21
VAL A 265
LEU A 268
VAL A 216
 None
 1.13A 3w68C-1nnhA:
undetectable		 3w68C-1nnhA:
24.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FEU_B_KANB301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 1nnh ASPARAGINYL-TRNA
SYNTHETASE-RELATED
PEPTIDE
(Pyrococcus
furiosus) 		4 / 7 ASP A 195
ASP A  52
ASP A 118
GLU A 192
 None
 1.12A 4feuB-1nnhA:
1.9		 4feuB-1nnhA:
20.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FEU_F_KANF301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 1nnh ASPARAGINYL-TRNA
SYNTHETASE-RELATED
PEPTIDE
(Pyrococcus
furiosus) 		4 / 8 ASP A 195
ASP A  52
ASP A 118
GLU A 192
 None
 1.07A 4feuF-1nnhA:
1.7		 4feuF-1nnhA:
20.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FEV_B_KANB301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 1nnh ASPARAGINYL-TRNA
SYNTHETASE-RELATED
PEPTIDE
(Pyrococcus
furiosus) 		4 / 7 ASP A 195
ASP A  52
ASP A 118
GLU A 192
 None
 1.13A 4fevB-1nnhA:
0.0		 4fevB-1nnhA:
20.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FEV_D_KAND301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 1nnh ASPARAGINYL-TRNA
SYNTHETASE-RELATED
PEPTIDE
(Pyrococcus
furiosus) 		4 / 7 ASP A 195
ASP A  52
ASP A 118
GLU A 192
 None
 1.12A 4fevD-1nnhA:
undetectable		 4fevD-1nnhA:
20.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FEV_F_KANF301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 1nnh ASPARAGINYL-TRNA
SYNTHETASE-RELATED
PEPTIDE
(Pyrococcus
furiosus) 		4 / 7 ASP A 195
ASP A  52
ASP A 118
GLU A 192
 None
 1.12A 4fevF-1nnhA:
1.8		 4fevF-1nnhA:
20.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FEW_B_KANB301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 1nnh ASPARAGINYL-TRNA
SYNTHETASE-RELATED
PEPTIDE
(Pyrococcus
furiosus) 		4 / 7 ASP A 195
ASP A  52
ASP A 118
GLU A 192
 None
 1.14A 4fewB-1nnhA:
0.0		 4fewB-1nnhA:
20.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FEW_D_KAND301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 1nnh ASPARAGINYL-TRNA
SYNTHETASE-RELATED
PEPTIDE
(Pyrococcus
furiosus) 		4 / 8 ASP A 195
ASP A  52
ASP A 118
GLU A 192
 None
 1.16A 4fewD-1nnhA:
1.8		 4fewD-1nnhA:
20.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FEW_F_KANF301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 1nnh ASPARAGINYL-TRNA
SYNTHETASE-RELATED
PEPTIDE
(Pyrococcus
furiosus) 		4 / 8 ASP A 195
ASP A  52
ASP A 118
GLU A 192
 None
 1.17A 4fewF-1nnhA:
1.9		 4fewF-1nnhA:
20.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FEX_B_KANB301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 1nnh ASPARAGINYL-TRNA
SYNTHETASE-RELATED
PEPTIDE
(Pyrococcus
furiosus) 		4 / 7 ASP A 195
ASP A  52
ASP A 118
GLU A 192
 None
 1.16A 4fexB-1nnhA:
1.8		 4fexB-1nnhA:
20.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4GKH_B_KANB301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 1nnh ASPARAGINYL-TRNA
SYNTHETASE-RELATED
PEPTIDE
(Pyrococcus
furiosus) 		4 / 8 ASP A 195
ASP A  52
ASP A 118
GLU A 192
 None
 1.13A 4gkhB-1nnhA:
1.9		 4gkhB-1nnhA:
20.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4GKH_D_KAND301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 1nnh ASPARAGINYL-TRNA
SYNTHETASE-RELATED
PEPTIDE
(Pyrococcus
furiosus) 		4 / 8 ASP A 195
ASP A  52
ASP A 118
GLU A 192
 None
 1.14A 4gkhD-1nnhA:
0.9		 4gkhD-1nnhA:
20.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4GKH_F_KANF301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 1nnh ASPARAGINYL-TRNA
SYNTHETASE-RELATED
PEPTIDE
(Pyrococcus
furiosus) 		4 / 8 ASP A 195
ASP A  52
ASP A 118
GLU A 192
 None
 1.15A 4gkhF-1nnhA:
1.8		 4gkhF-1nnhA:
20.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4GKH_G_KANG301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 1nnh ASPARAGINYL-TRNA
SYNTHETASE-RELATED
PEPTIDE
(Pyrococcus
furiosus) 		4 / 7 ASP A 195
ASP A  52
ASP A 118
GLU A 192
 None
 1.14A 4gkhG-1nnhA:
undetectable		 4gkhG-1nnhA:
20.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4GKH_J_KANJ301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 1nnh ASPARAGINYL-TRNA
SYNTHETASE-RELATED
PEPTIDE
(Pyrococcus
furiosus) 		4 / 6 ASP A 195
ASP A  52
ASP A 118
GLU A 192
 None
 1.14A 4gkhJ-1nnhA:
1.8		 4gkhJ-1nnhA:
20.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4GKH_K_KANK301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 1nnh ASPARAGINYL-TRNA
SYNTHETASE-RELATED
PEPTIDE
(Pyrococcus
furiosus) 		4 / 8 ASP A 195
ASP A  52
ASP A 118
GLU A 192
 None
 1.12A 4gkhC-1nnhA:
1.7
4gkhK-1nnhA:
0.6		 4gkhC-1nnhA:
20.79
4gkhK-1nnhA:
20.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4GKI_A_KANA301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 1nnh ASPARAGINYL-TRNA
SYNTHETASE-RELATED
PEPTIDE
(Pyrococcus
furiosus) 		4 / 8 ASP A 195
ASP A  52
ASP A 118
GLU A 192
 None
 1.16A 4gkiA-1nnhA:
1.7		 4gkiA-1nnhA:
20.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4GKI_C_KANC301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 1nnh ASPARAGINYL-TRNA
SYNTHETASE-RELATED
PEPTIDE
(Pyrococcus
furiosus) 		4 / 8 ASP A 195
ASP A  52
ASP A 118
GLU A 192
 None
 1.14A 4gkiC-1nnhA:
0.0		 4gkiC-1nnhA:
20.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4GKI_G_KANG301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 1nnh ASPARAGINYL-TRNA
SYNTHETASE-RELATED
PEPTIDE
(Pyrococcus
furiosus) 		4 / 8 ASP A 195
ASP A  52
ASP A 118
GLU A 192
 None
 1.13A 4gkiE-1nnhA:
undetectable
4gkiG-1nnhA:
1.9		 4gkiE-1nnhA:
20.79
4gkiG-1nnhA:
20.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OJ4_A_DIFA501_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 1nnh ASPARAGINYL-TRNA
SYNTHETASE-RELATED
PEPTIDE
(Pyrococcus
furiosus) 		4 / 8 LEU A  94
LEU A 117
VAL A 265
ILE A  21
 None
 0.90A 4oj4A-1nnhA:
undetectable		 4oj4A-1nnhA:
19.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RDX_A_HISA502_0
(HISTIDINE--TRNA
LIGASE)		 1nnh ASPARAGINYL-TRNA
SYNTHETASE-RELATED
PEPTIDE
(Pyrococcus
furiosus) 		4 / 7 GLU A 120
ARG A 191
GLY A 219
GLY A 260
 None
 0.79A 4rdxA-1nnhA:
15.4		 4rdxA-1nnhA:
25.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XUM_A_IMNA502_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 1nnh ASPARAGINYL-TRNA
SYNTHETASE-RELATED
PEPTIDE
(Pyrococcus
furiosus) 		4 / 7 ILE A  21
ARG A 267
LEU A 209
ILE A 263
 None
 0.93A 4xumA-1nnhA:
undetectable		 4xumA-1nnhA:
19.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5C0O_G_SAMG301_1
(TRNA
(ADENINE(58)-N(1))-M
ETHYLTRANSFERASE
TRMI)		 1nnh ASPARAGINYL-TRNA
SYNTHETASE-RELATED
PEPTIDE
(Pyrococcus
furiosus) 		3 / 3 GLU A 101
HIS A 110
ASP A  52
 None
 0.81A 5c0oG-1nnhA:
undetectable		 5c0oG-1nnhA:
24.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IFU_B_GBMB801_1
(PROLINE--TRNA LIGASE)		 1nnh ASPARAGINYL-TRNA
SYNTHETASE-RELATED
PEPTIDE
(Pyrococcus
furiosus) 		5 / 9 ILE A  21
LEU A  22
GLU A 266
THR A 115
GLY A 264
 None
 1.19A 5ifuB-1nnhA:
7.0		 5ifuB-1nnhA:
21.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BNI_A_ADNA602_1
(LYSINE--TRNA LIGASE)		 1nnh ASPARAGINYL-TRNA
SYNTHETASE-RELATED
PEPTIDE
(Pyrococcus
furiosus) 		8 / 10 ASN A  97
ARG A  99
GLU A 101
HIS A 110
PHE A 114
GLU A 215
GLY A 264
ARG A 267
 None
 0.73A 6bniA-1nnhA:
28.1		 6bniA-1nnhA:
14.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BNI_A_ADNA602_1
(LYSINE--TRNA LIGASE)		 1nnh ASPARAGINYL-TRNA
SYNTHETASE-RELATED
PEPTIDE
(Pyrococcus
furiosus) 		8 / 10 ASN A  97
ARG A  99
GLU A 101
HIS A 110
PHE A 114
GLY A 264
ARG A 267
ILE A 278
 None
 0.55A 6bniA-1nnhA:
28.1		 6bniA-1nnhA:
14.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BNI_B_ADNB602_1
(LYSINE--TRNA LIGASE)		 1nnh ASPARAGINYL-TRNA
SYNTHETASE-RELATED
PEPTIDE
(Pyrococcus
furiosus) 		8 / 10 ASN A  97
ARG A  99
GLU A 101
HIS A 110
PHE A 114
GLU A 215
GLY A 264
ARG A 267
 None
 0.72A 6bniB-1nnhA:
28.0		 6bniB-1nnhA:
14.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BNI_B_ADNB602_1
(LYSINE--TRNA LIGASE)		 1nnh ASPARAGINYL-TRNA
SYNTHETASE-RELATED
PEPTIDE
(Pyrococcus
furiosus) 		8 / 10 ASN A  97
ARG A  99
GLU A 101
HIS A 110
PHE A 114
GLY A 264
ARG A 267
ILE A 278
 None
 0.53A 6bniB-1nnhA:
28.0		 6bniB-1nnhA:
14.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CA1_A_MIGA701_1
(GLYCOSYL HYDROLASE,
FAMILY 31)		 1nnh ASPARAGINYL-TRNA
SYNTHETASE-RELATED
PEPTIDE
(Pyrococcus
furiosus) 		5 / 12 ASP A 173
ILE A 208
ILE A 186
ARG A 191
ASP A  52
 None
 1.20A 6ca1A-1nnhA:
undetectable		 6ca1A-1nnhA:
14.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CA1_A_MIGA701_1
(GLYCOSYL HYDROLASE,
FAMILY 31)		 1nnh ASPARAGINYL-TRNA
SYNTHETASE-RELATED
PEPTIDE
(Pyrococcus
furiosus) 		5 / 12 ASP A 173
ILE A 208
ILE A 186
ASP A 206
ASP A  52
 None
 1.34A 6ca1A-1nnhA:
undetectable		 6ca1A-1nnhA:
14.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CA1_B_MIGB701_1
(GLYCOSYL HYDROLASE,
FAMILY 31)		 1nnh ASPARAGINYL-TRNA
SYNTHETASE-RELATED
PEPTIDE
(Pyrococcus
furiosus) 		5 / 12 ASP A 173
ILE A 208
ILE A 186
ARG A 191
ASP A  52
 None
 1.20A 6ca1B-1nnhA:
undetectable		 6ca1B-1nnhA:
14.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CA1_B_MIGB701_1
(GLYCOSYL HYDROLASE,
FAMILY 31)		 1nnh ASPARAGINYL-TRNA
SYNTHETASE-RELATED
PEPTIDE
(Pyrococcus
furiosus) 		5 / 12 ASP A 173
ILE A 208
ILE A 186
ASP A 206
ASP A  52
 None
 1.33A 6ca1B-1nnhA:
undetectable		 6ca1B-1nnhA:
14.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CA3_A_MIGA701_1
(GLYCOSYL HYDROLASE,
FAMILY 31)		 1nnh ASPARAGINYL-TRNA
SYNTHETASE-RELATED
PEPTIDE
(Pyrococcus
furiosus) 		5 / 12 ASP A 173
ILE A 208
ILE A 186
ARG A 191
ASP A  52
 None
 1.18A 6ca3A-1nnhA:
undetectable		 6ca3A-1nnhA:
14.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CA3_A_MIGA701_1
(GLYCOSYL HYDROLASE,
FAMILY 31)		 1nnh ASPARAGINYL-TRNA
SYNTHETASE-RELATED
PEPTIDE
(Pyrococcus
furiosus) 		5 / 12 ASP A 173
ILE A 208
ILE A 186
ASP A 206
ASP A  52
 None
 1.29A 6ca3A-1nnhA:
undetectable		 6ca3A-1nnhA:
14.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CA3_B_MIGB701_1
(GLYCOSYL HYDROLASE,
FAMILY 31)		 1nnh ASPARAGINYL-TRNA
SYNTHETASE-RELATED
PEPTIDE
(Pyrococcus
furiosus) 		5 / 12 ASP A 173
ILE A 208
ILE A 186
ARG A 191
ASP A  52
 None
 1.17A 6ca3B-1nnhA:
undetectable		 6ca3B-1nnhA:
14.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CA3_B_MIGB701_1
(GLYCOSYL HYDROLASE,
FAMILY 31)		 1nnh ASPARAGINYL-TRNA
SYNTHETASE-RELATED
PEPTIDE
(Pyrococcus
furiosus) 		5 / 12 ASP A 173
ILE A 208
ILE A 186
ASP A 206
ASP A  52
 None
 1.29A 6ca3B-1nnhA:
undetectable		 6ca3B-1nnhA:
14.80