SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1nnt'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HK1_A_T44A3003_1
(SERUM ALBUMIN)		 1nnt OVOTRANSFERRIN
(Gallus
gallus) 		4 / 6 HIS A 250
LYS A  75
ALA A 254
VAL A 310
 FE  A 333 ( 3.5A)
None
None
None
 1.02A 1hk1A-1nntA:
undetectable		 1hk1A-1nntA:
19.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1I9G_A_SAMA301_1
(HYPOTHETICAL PROTEIN
RV2118C)		 1nnt OVOTRANSFERRIN
(Gallus
gallus) 		3 / 3 GLU A  80
HIS A 250
ASP A 302
 None
FE  A 333 ( 3.5A)
None
 0.78A 1i9gA-1nntA:
undetectable		 1i9gA-1nntA:
20.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P93_B_DEXB2999_1
(GLUCOCORTICOID
RECEPTOR)		 1nnt OVOTRANSFERRIN
(Gallus
gallus) 		5 / 12 MET A 331
GLY A  62
GLN A  63
LEU A 119
ARG A 184
 None
 1.45A 1p93B-1nntA:
undetectable		 1p93B-1nntA:
19.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RLF_A_RIMA199_1
(MATRIX PROTEIN 2)		 1nnt OVOTRANSFERRIN
(Gallus
gallus) 		4 / 6 LEU A 267
LEU A 307
ILE A 263
ARG A 309
 None
 1.07A 2rlfA-1nntA:
undetectable
2rlfB-1nntA:
0.0		 2rlfA-1nntA:
8.12
2rlfB-1nntA:
8.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RLF_C_RIMC399_1
(MATRIX PROTEIN 2)		 1nnt OVOTRANSFERRIN
(Gallus
gallus) 		4 / 6 LEU A 267
LEU A 307
ILE A 263
ARG A 309
 None
 0.97A 2rlfC-1nntA:
0.0
2rlfD-1nntA:
undetectable		 2rlfC-1nntA:
8.12
2rlfD-1nntA:
8.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CV9_A_VDXA501_1
(CYTOCHROME P450-SU1)		 1nnt OVOTRANSFERRIN
(Gallus
gallus) 		5 / 9 VAL A 247
SER A  91
ARG A 246
ILE A 129
GLY A 120
 None
 1.16A 3cv9A-1nntA:
undetectable		 3cv9A-1nntA:
20.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QJ7_A_SPMA264_1
(THYMIDYLATE SYNTHASE)		 1nnt OVOTRANSFERRIN
(Gallus
gallus) 		4 / 8 ARG A 246
ALA A 249
TYR A 319
SER A 122
 None
None
None
FE  A 333 ( 4.9A)
 1.02A 3qj7A-1nntA:
undetectable
3qj7D-1nntA:
undetectable		 3qj7A-1nntA:
20.68
3qj7D-1nntA:
20.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S53_A_017A201_1
(PROTEASE)		 1nnt OVOTRANSFERRIN
(Gallus
gallus) 		5 / 9 GLY A  68
ALA A  67
ILE A  57
GLY A  61
ILE A  77
 None
 0.91A 3s53A-1nntA:
undetectable		 3s53A-1nntA:
15.09
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4G77_A_TLFA711_0
(LACTOTRANSFERRIN)		 1nnt OVOTRANSFERRIN
(Gallus
gallus) 		4 / 7 ILE A 127
ALA A 245
TYR A 324
ALA A 327
 None
 0.53A 4g77A-1nntA:
41.0		 4g77A-1nntA:
39.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NC3_A_ERMA1202_2
(CHIMERA PROTEIN OF
HUMAN
5-HYDROXYTRYPTAMINE
RECEPTOR 2B AND E.
COLI SOLUBLE
CYTOCHROME B562)		 1nnt OVOTRANSFERRIN
(Gallus
gallus) 		4 / 6 LEU A 229
GLN A 234
LEU A 226
GLU A 225
 None
 1.17A 4nc3A-1nntA:
undetectable		 4nc3A-1nntA:
21.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RMJ_A_NCAA402_0
(NAD-DEPENDENT
PROTEIN DEACETYLASE
SIRTUIN-2)		 1nnt OVOTRANSFERRIN
(Gallus
gallus) 		4 / 7 PHE A 266
LEU A 267
LEU A 284
ASP A 273
 None
 0.86A 4rmjA-1nntA:
undetectable		 4rmjA-1nntA:
21.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5A06_A_SORA1341_0
(ALDOSE-ALDOSE
OXIDOREDUCTASE)		 1nnt OVOTRANSFERRIN
(Gallus
gallus) 		4 / 7 PHE A  65
ARG A 332
TYR A  72
TYR A  42
 None
 1.39A 5a06A-1nntA:
undetectable		 5a06A-1nntA:
23.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5A06_C_SORC1341_0
(ALDOSE-ALDOSE
OXIDOREDUCTASE)		 1nnt OVOTRANSFERRIN
(Gallus
gallus) 		4 / 7 PHE A  65
ARG A 332
TYR A  72
TYR A  42
 None
 1.38A 5a06C-1nntA:
undetectable		 5a06C-1nntA:
23.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5A06_D_SORD1342_0
(ALDOSE-ALDOSE
OXIDOREDUCTASE)		 1nnt OVOTRANSFERRIN
(Gallus
gallus) 		4 / 7 PHE A  65
ARG A 332
TYR A  72
TYR A  42
 None
 1.39A 5a06D-1nntA:
undetectable		 5a06D-1nntA:
23.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5A06_E_SORE1342_0
(ALDOSE-ALDOSE
OXIDOREDUCTASE)		 1nnt OVOTRANSFERRIN
(Gallus
gallus) 		4 / 7 PHE A  65
ARG A 332
TYR A  72
TYR A  42
 None
 1.41A 5a06E-1nntA:
undetectable		 5a06E-1nntA:
23.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5A06_F_SORF1343_0
(ALDOSE-ALDOSE
OXIDOREDUCTASE)		 1nnt OVOTRANSFERRIN
(Gallus
gallus) 		4 / 7 PHE A  65
ARG A 332
TYR A  72
TYR A  42
 None
 1.36A 5a06F-1nntA:
undetectable		 5a06F-1nntA:
23.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5C0O_G_SAMG301_1
(TRNA
(ADENINE(58)-N(1))-M
ETHYLTRANSFERASE
TRMI)		 1nnt OVOTRANSFERRIN
(Gallus
gallus) 		3 / 3 GLU A  80
HIS A 250
ASP A 302
 None
FE  A 333 ( 3.5A)
None
 0.80A 5c0oG-1nntA:
undetectable		 5c0oG-1nntA:
22.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EB3_A_UEGA202_1
(YFIR)		 1nnt OVOTRANSFERRIN
(Gallus
gallus) 		4 / 4 LEU A  43
ILE A  46
PRO A  71
LEU A  69
 None
 1.01A 5eb3A-1nntA:
undetectable		 5eb3A-1nntA:
19.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FSA_A_X2NA590_2
(CYP51 VARIANT1)		 1nnt OVOTRANSFERRIN
(Gallus
gallus) 		3 / 3 PRO A  76
ILE A 305
SER A 316
 None
 0.79A 5fsaA-1nntA:
undetectable		 5fsaA-1nntA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KC0_A_RBFA303_2
(RIBOFLAVIN
TRANSPORTER RIBU)		 1nnt OVOTRANSFERRIN
(Gallus
gallus) 		3 / 3 LYS A 169
LEU A 119
ILE A 166
 None
 0.77A 5kc0A-1nntA:
undetectable		 5kc0A-1nntA:
19.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UC1_A_486A801_1
(GLUCOCORTICOID
RECEPTOR)		 1nnt OVOTRANSFERRIN
(Gallus
gallus) 		5 / 12 GLY A  62
GLY A  61
GLN A  63
LEU A 119
ARG A 184
 None
 1.10A 5uc1A-1nntA:
undetectable		 5uc1A-1nntA:
14.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UC1_B_486B801_2
(GLUCOCORTICOID
RECEPTOR)		 1nnt OVOTRANSFERRIN
(Gallus
gallus) 		5 / 12 GLY A  62
GLY A  61
GLN A  63
LEU A 119
ARG A 184
 None
 1.01A 5uc1B-1nntA:
undetectable		 5uc1B-1nntA:
14.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VKQ_A_PCFA1807_0
(NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L)		 1nnt OVOTRANSFERRIN
(Gallus
gallus) 		5 / 7 LEU A 267
LEU A  59
ILE A   7
LEU A  34
ILE A  12
 None
 1.34A 5vkqA-1nntA:
undetectable
5vkqB-1nntA:
undetectable		 5vkqA-1nntA:
11.40
5vkqB-1nntA:
11.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VKQ_B_PCFB1804_0
(NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L)		 1nnt OVOTRANSFERRIN
(Gallus
gallus) 		6 / 8 LEU A 267
LEU A  59
VAL A 252
ILE A   7
LEU A  34
ILE A  12
 None
 1.39A 5vkqB-1nntA:
undetectable
5vkqC-1nntA:
undetectable		 5vkqB-1nntA:
11.40
5vkqC-1nntA:
11.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VKQ_C_PCFC1805_0
(NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L)		 1nnt OVOTRANSFERRIN
(Gallus
gallus) 		6 / 9 LEU A 267
LEU A  59
VAL A 252
ILE A   7
LEU A  34
ILE A  12
 None
 1.40A 5vkqC-1nntA:
0.0
5vkqD-1nntA:
undetectable		 5vkqC-1nntA:
11.40
5vkqD-1nntA:
11.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EXI_D_ADND502_1
(ADENOSYLHOMOCYSTEINA
SE)		 1nnt OVOTRANSFERRIN
(Gallus
gallus) 		3 / 3 LEU A  69
ASN A 126
LEU A 320
 None
 0.75A 6exiD-1nntA:
undetectable		 6exiD-1nntA:
12.54