SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1nnv'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1TKQ_A_DVAA6_0 (MINI-GRAMICIDIN A)	1nnv	HYPOTHETICAL PROTEIN HI1450 (Haemophilus influenzae)	3 / 3	ALA A 70 VAL A 50 TRP A 73	None	1.01A	1tkqA-1nnvA: undetectable	1tkqA-1nnvA: 7.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2ZW9_B_SAMB801_0 (LEUCINE CARBOXYL METHYLTRANSFERASE 2)	1nnv	HYPOTHETICAL PROTEIN HI1450 (Haemophilus influenzae)	5 / 12	GLN A 40 GLY A 75 GLY A 45 ASP A 33 GLU A 48	None	1.22A	2zw9B-1nnvA: undetectable	2zw9B-1nnvA: 9.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4M5M_A_DX4A401_0 (2-AMINO-4-HYDROXY-6- HYDROXYMETHYLDIHYDRO PTERIDINE PYROPHOSPHOKINASE)	1nnv	HYPOTHETICAL PROTEIN HI1450 (Haemophilus influenzae)	4 / 8	GLY A 45 LEU A 36 ARG A 44 PHE A 87	None	1.16A	4m5mA-1nnvA: undetectable	4m5mA-1nnvA: 22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6HD6_B_STIB601_1 (TYROSINE-PROTEIN KINASE ABL1)	1nnv	HYPOTHETICAL PROTEIN HI1450 (Haemophilus influenzae)	4 / 7	VAL A 50 MET A 24 GLY A 26 ALA A 88	None	0.83A	6hd6B-1nnvA: undetectable	6hd6B-1nnvA: 22.02

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1TKQ_A_DVAA6_0","MINI-GRAMICIDIN A","1nnv","HYPOTHETICAL PROTEIN HI1450","Haemophilus influenzae",3,"ALA A  70;VAL A  50;TRP A  73","None","1.01A","1tkqA-1nnvA:undetectable","1tkqA-1nnvA:7.37"],["2ZW9_B_SAMB801_0","LEUCINE CARBOXYL METHYLTRANSFERASE 2","1nnv","HYPOTHETICAL PROTEIN HI1450","Haemophilus influenzae",5,"GLN A  40;GLY A  75;GLY A  45;ASP A  33;GLU A  48","None","1.22A","2zw9B-1nnvA:undetectable","2zw9B-1nnvA:9.34"],["4M5M_A_DX4A401_0","2-AMINO-4-HYDROXY-6-HYDROXYMETHYLDIHYDROPTERIDINE PYROPHOSPHOKINASE","1nnv","HYPOTHETICAL PROTEIN HI1450","Haemophilus influenzae",4,"GLY A  45;LEU A  36;ARG A  44;PHE A  87","None","1.16A","4m5mA-1nnvA:undetectable","4m5mA-1nnvA:22.22"],["6HD6_B_STIB601_1","TYROSINE-PROTEIN KINASE ABL1","1nnv","HYPOTHETICAL PROTEIN HI1450","Haemophilus influenzae",4,"VAL A  50;MET A  24;GLY A  26;ALA A  88","None","0.83A","6hd6B-1nnvA:undetectable","6hd6B-1nnvA:22.02"]]