SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1no7'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1AFS_A_TESA325_1
(3-ALPHA-HYDROXYSTERO
ID DEHYDROGENASE)		 1no7 MAJOR CAPSID PROTEIN
(Human
alphaherpesvirus
1) 		4 / 7 LEU A 963
TYR A 814
HIS A 961
ASN A 581
 None
 1.14A 1afsA-1no7A:
0.0		 1afsA-1no7A:
19.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1AFS_B_TESB325_1
(3-ALPHA-HYDROXYSTERO
ID DEHYDROGENASE)		 1no7 MAJOR CAPSID PROTEIN
(Human
alphaherpesvirus
1) 		4 / 7 LEU A 963
TYR A 814
HIS A 961
ASN A 581
 None
 1.15A 1afsB-1no7A:
0.0		 1afsB-1no7A:
19.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1CEB_A_AMHA90_1
(PLASMINOGEN)		 1no7 MAJOR CAPSID PROTEIN
(Human
alphaherpesvirus
1) 		4 / 7 ASP A 738
ASP A 740
TRP A 805
TYR A 673
 None
 1.16A 1cebA-1no7A:
undetectable		 1cebA-1no7A:
7.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E7B_A_HLTA4002_1
(SERUM ALBUMIN)		 1no7 MAJOR CAPSID PROTEIN
(Human
alphaherpesvirus
1) 		4 / 4 ARG A 660
ALA A 613
ALA A 688
GLU A 685
 None
 1.10A 1e7bA-1no7A:
0.0		 1e7bA-1no7A:
21.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E7B_B_HLTB4002_1
(SERUM ALBUMIN)		 1no7 MAJOR CAPSID PROTEIN
(Human
alphaherpesvirus
1) 		4 / 4 ARG A 660
ALA A 613
ALA A 688
GLU A 685
 None
 1.10A 1e7bB-1no7A:
undetectable		 1e7bB-1no7A:
21.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E7C_A_HLTA4002_1
(SERUM ALBUMIN)		 1no7 MAJOR CAPSID PROTEIN
(Human
alphaherpesvirus
1) 		4 / 5 ARG A 660
ALA A 613
ALA A 688
GLU A 685
 None
 1.15A 1e7cA-1no7A:
0.0		 1e7cA-1no7A:
21.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FDU_A_ESTA351_1
(17-BETA-HYDROXYSTERO
ID DEHYDROGENASE)		 1no7 MAJOR CAPSID PROTEIN
(Human
alphaherpesvirus
1) 		5 / 12 GLY A 488
GLY A 995
PHE A 505
LEU A 963
VAL A1007
 None
 1.10A 1fduA-1no7A:
undetectable		 1fduA-1no7A:
20.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1H4O_A_BEZA1162_0
(PEROXIREDOXIN 5)		 1no7 MAJOR CAPSID PROTEIN
(Human
alphaherpesvirus
1) 		5 / 10 PRO A 564
PRO A 568
GLY A 567
LEU A 558
GLY A 552
 None
 1.33A 1h4oA-1no7A:
undetectable
1h4oB-1no7A:
undetectable		 1h4oA-1no7A:
15.73
1h4oB-1no7A:
15.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TYR_B_9CRB130_1
(TRANSTHYRETIN)		 1no7 MAJOR CAPSID PROTEIN
(Human
alphaherpesvirus
1) 		4 / 7 LEU A 994
THR A 905
LEU A 909
SER A 757
 None
 0.98A 1tyrB-1no7A:
undetectable		 1tyrB-1no7A:
11.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TYR_B_9CRB130_1
(TRANSTHYRETIN)		 1no7 MAJOR CAPSID PROTEIN
(Human
alphaherpesvirus
1) 		4 / 7 THR A 905
ALA A 907
LEU A 909
SER A 757
 None
 0.99A 1tyrB-1no7A:
undetectable		 1tyrB-1no7A:
11.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1X70_B_715B801_2
(DIPEPTIDYL PEPTIDASE
IV)		 1no7 MAJOR CAPSID PROTEIN
(Human
alphaherpesvirus
1) 		3 / 3 PHE A 618
TYR A 813
TYR A 668
 None
 1.01A 1x70B-1no7A:
0.0		 1x70B-1no7A:
19.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXK_A_IMNA2001_1
(SERUM ALBUMIN)		 1no7 MAJOR CAPSID PROTEIN
(Human
alphaherpesvirus
1) 		4 / 8 SER A 757
ALA A 498
LEU A 958
ASP A 562
 None
 1.16A 2bxkA-1no7A:
0.0		 2bxkA-1no7A:
21.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2D55_C_DVAC8_0
(ACTINOMYCIN D)		 1no7 MAJOR CAPSID PROTEIN
(Human
alphaherpesvirus
1) 		3 / 3 PRO A 861
THR A 859
PRO A 857
 None
 0.62A 2d55C-1no7A:
undetectable		 2d55C-1no7A:
2.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2G72_B_SAMB2002_0
(PHENYLETHANOLAMINE
N-METHYLTRANSFERASE)		 1no7 MAJOR CAPSID PROTEIN
(Human
alphaherpesvirus
1) 		5 / 12 GLN A 943
LEU A 630
ILE A 937
VAL A 830
VAL A 835
 None
 1.09A 2g72B-1no7A:
undetectable		 2g72B-1no7A:
18.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QBN_A_CAMA442_0
(CYTOCHROME P450-CAM)		 1no7 MAJOR CAPSID PROTEIN
(Human
alphaherpesvirus
1) 		4 / 7 TYR A 812
VAL A 689
VAL A 674
VAL A 675
 None
 0.95A 2qbnA-1no7A:
0.0		 2qbnA-1no7A:
20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A51_D_VDYD6178_1
(VITAMIN D
HYDROXYLASE)		 1no7 MAJOR CAPSID PROTEIN
(Human
alphaherpesvirus
1) 		5 / 12 ILE A 937
LEU A 939
ILE A 949
VAL A 835
LEU A 629
 None
 1.23A 3a51D-1no7A:
0.0		 3a51D-1no7A:
21.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CWK_A_REAA300_1
(CELLULAR RETINOIC
ACID-BINDING PROTEIN
2)		 1no7 MAJOR CAPSID PROTEIN
(Human
alphaherpesvirus
1) 		5 / 12 LEU A 989
ALA A 965
PRO A 818
VAL A1010
ARG A1011
 None
 1.16A 3cwkA-1no7A:
0.1		 3cwkA-1no7A:
11.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D91_B_REMB350_2
(RENIN)		 1no7 MAJOR CAPSID PROTEIN
(Human
alphaherpesvirus
1) 		4 / 4 VAL A 665
TYR A 813
PRO A 818
PHE A 618
 None
 1.32A 3d91B-1no7A:
0.0		 3d91B-1no7A:
20.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3H52_C_486C4_2
(GLUCOCORTICOID
RECEPTOR)		 1no7 MAJOR CAPSID PROTEIN
(Human
alphaherpesvirus
1) 		3 / 3 MET A 940
CYH A 661
PRO A 624
 None
 1.24A 3h52C-1no7A:
undetectable		 3h52C-1no7A:
16.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K13_A_THHA642_1
(5-METHYLTETRAHYDROFO
LATE-HOMOCYSTEINE
METHYLTRANSFERASE)		 1no7 MAJOR CAPSID PROTEIN
(Human
alphaherpesvirus
1) 		3 / 3 ASN A 997
ASP A 548
ARG A 595
 None
 0.93A 3k13A-1no7A:
undetectable		 3k13A-1no7A:
19.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OZW_A_KKKA413_1
(FLAVOHEMOGLOBIN)		 1no7 MAJOR CAPSID PROTEIN
(Human
alphaherpesvirus
1) 		4 / 8 ILE A1002
ALA A 962
LEU A 963
LEU A1024
 None
 0.87A 3ozwA-1no7A:
undetectable		 3ozwA-1no7A:
21.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P2K_D_SAMD6735_0
(16S RRNA METHYLASE)		 1no7 MAJOR CAPSID PROTEIN
(Human
alphaherpesvirus
1) 		5 / 12 GLY A 931
ALA A 498
LEU A 958
TYR A 956
SER A1000
 None
 1.04A 3p2kD-1no7A:
undetectable		 3p2kD-1no7A:
15.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PGH_A_FLPA701_1
(CYCLOOXYGENASE-2)		 1no7 MAJOR CAPSID PROTEIN
(Human
alphaherpesvirus
1) 		5 / 12 VAL A1010
LEU A 700
GLY A 596
ALA A1023
LEU A1020
 None
 1.15A 3pghA-1no7A:
0.9		 3pghA-1no7A:
20.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AT0_A_ACTA1490_0
(3-KETOSTEROID-DELTA4
-5ALPHA-DEHYDROGENAS
E)		 1no7 MAJOR CAPSID PROTEIN
(Human
alphaherpesvirus
1) 		3 / 3 GLU A 638
TYR A 673
SER A 669
 None
 1.02A 4at0A-1no7A:
undetectable		 4at0A-1no7A:
23.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AT0_A_ACTA1490_0
(3-KETOSTEROID-DELTA4
-5ALPHA-DEHYDROGENAS
E)		 1no7 MAJOR CAPSID PROTEIN
(Human
alphaherpesvirus
1) 		3 / 3 GLU A 638
TYR A 673
SER A 672
 None
 0.97A 4at0A-1no7A:
undetectable		 4at0A-1no7A:
23.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D7B_B_TCWB1126_1
(TRANSTHYRETIN)		 1no7 MAJOR CAPSID PROTEIN
(Human
alphaherpesvirus
1) 		5 / 7 LEU A 994
THR A 905
ALA A 907
LEU A 909
SER A 757
 None
 1.25A 4d7bA-1no7A:
undetectable		 4d7bA-1no7A:
11.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K13_A_ETSA304_1
(CARBONIC ANHYDRASE 2)		 1no7 MAJOR CAPSID PROTEIN
(Human
alphaherpesvirus
1) 		5 / 12 LEU A 647
LEU A 630
VAL A 626
LEU A 839
THR A 838
 None
 0.97A 4k13A-1no7A:
undetectable		 4k13A-1no7A:
16.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XP1_A_LDPA708_1
(DOPAMINE
TRANSPORTER, ISOFORM
B)		 1no7 MAJOR CAPSID PROTEIN
(Human
alphaherpesvirus
1) 		5 / 10 PHE A 550
ALA A 996
VAL A 491
PHE A 999
GLY A 488
 None
 1.38A 4xp1A-1no7A:
undetectable		 4xp1A-1no7A:
24.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZPH_A_PRLA501_0
(ARYL HYDROCARBON
RECEPTOR NUCLEAR
TRANSLOCATOR
ENDOTHELIAL PAS
DOMAIN-CONTAINING
PROTEIN 1)		 1no7 MAJOR CAPSID PROTEIN
(Human
alphaherpesvirus
1) 		4 / 7 GLN A 631
TRP A 737
LEU A 670
SER A 669
 None
 0.90A 4zphA-1no7A:
0.0
4zphB-1no7A:
0.0		 4zphA-1no7A:
18.89
4zphB-1no7A:
19.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DZK_P_BEZP801_0
(ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 2
BEZ-LEU-LEU)		 1no7 MAJOR CAPSID PROTEIN
(Human
alphaherpesvirus
1) 		4 / 5 SER A1013
ALA A1014
HIS A1009
LEU A1020
 None
 1.31A 5dzkb-1no7A:
undetectable
5dzkp-1no7A:
undetectable		 5dzkb-1no7A:
15.13
5dzkp-1no7A:
50.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IKT_B_TLFB601_0
(PROSTAGLANDIN G/H
SYNTHASE 2)		 1no7 MAJOR CAPSID PROTEIN
(Human
alphaherpesvirus
1) 		5 / 12 VAL A1010
LEU A 700
GLY A 596
ALA A1023
LEU A1020
 None
 1.25A 5iktB-1no7A:
undetectable		 5iktB-1no7A:
20.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5V0V_A_8QPA613_1
(SERUM ALBUMIN)		 1no7 MAJOR CAPSID PROTEIN
(Human
alphaherpesvirus
1) 		4 / 8 ARG A1011
ALA A 967
VAL A 970
THR A 827
 None
 0.80A 5v0vA-1no7A:
undetectable		 5v0vA-1no7A:
22.06