SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1no8'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V55_W_CHDW4060_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE I
CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART)		 1no8 ALY
(Mus
musculus) 		5 / 8 ILE A 121
LEU A 124
PHE A 125
MET A 175
LEU A 170
 None
 1.26A 1v55N-1no8A:
undetectable
1v55W-1no8A:
undetectable		 1v55N-1no8A:
11.24
1v55W-1no8A:
28.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIN_J_CHDJ60_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 1)		 1no8 ALY
(Mus
musculus) 		5 / 8 ILE A 121
LEU A 124
PHE A 125
MET A 175
LEU A 170
 None
 1.29A 2einA-1no8A:
undetectable
2einJ-1no8A:
undetectable		 2einA-1no8A:
11.24
2einJ-1no8A:
28.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABK_J_CHDJ60_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 1)		 1no8 ALY
(Mus
musculus) 		5 / 8 ILE A 121
LEU A 124
PHE A 125
MET A 175
LEU A 170
 None
 1.20A 3abkA-1no8A:
undetectable
3abkJ-1no8A:
undetectable		 3abkA-1no8A:
11.24
3abkJ-1no8A:
28.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABM_W_CHDW1060_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 1)		 1no8 ALY
(Mus
musculus) 		5 / 8 ILE A 121
LEU A 124
PHE A 125
MET A 175
LEU A 170
 None
 1.26A 3abmN-1no8A:
undetectable
3abmW-1no8A:
undetectable		 3abmN-1no8A:
11.24
3abmW-1no8A:
28.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG3_W_CHDW1059_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 1)		 1no8 ALY
(Mus
musculus) 		5 / 8 ILE A 121
LEU A 124
PHE A 125
MET A 175
LEU A 170
 None
 1.18A 3ag3N-1no8A:
undetectable
3ag3W-1no8A:
undetectable		 3ag3N-1no8A:
11.24
3ag3W-1no8A:
28.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ASO_W_CHDW1059_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1)		 1no8 ALY
(Mus
musculus) 		5 / 8 ILE A 121
LEU A 124
PHE A 125
MET A 175
LEU A 170
 None
 1.24A 3asoN-1no8A:
undetectable
3asoW-1no8A:
undetectable		 3asoN-1no8A:
11.24
3asoW-1no8A:
28.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCP_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 1no8 ALY
(Mus
musculus) 		5 / 8 ILE A 121
LEU A 124
PHE A 125
MET A 175
LEU A 170
 None
 1.25A 5zcpN-1no8A:
undetectable
5zcpW-1no8A:
undetectable		 5zcpN-1no8A:
11.24
5zcpW-1no8A:
28.41