SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1nog'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID
Hit
Macromolecule
Res.
Matches
Interface HETATM RMSD Dali
Z-score
Seq.
Identity (%)
View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GFZ_A_CFFA940_1
(GLYCOGEN
PHOSPHORYLASE)
1nog CONSERVED
HYPOTHETICAL PROTEIN
TA0546

(Thermoplasma
acidophilum)
4 / 6 PHE A  38
ALA A  42
GLY A  40
TYR A  41
None
1.11A 1gfzA-1nogA:
undetectable
1gfzA-1nogA:
13.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L5Q_A_CFFA863_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)
1nog CONSERVED
HYPOTHETICAL PROTEIN
TA0546

(Thermoplasma
acidophilum)
4 / 6 PHE A  38
ALA A  42
GLY A  40
TYR A  41
None
1.15A 1l5qA-1nogA:
undetectable
1l5qA-1nogA:
12.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L7X_A_CFFA863_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)
1nog CONSERVED
HYPOTHETICAL PROTEIN
TA0546

(Thermoplasma
acidophilum)
4 / 6 PHE A  38
ALA A  42
GLY A  40
TYR A  41
None
1.11A 1l7xA-1nogA:
1.9
1l7xA-1nogA:
12.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L7X_B_CFFB1863_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)
1nog CONSERVED
HYPOTHETICAL PROTEIN
TA0546

(Thermoplasma
acidophilum)
4 / 6 PHE A  38
ALA A  42
GLY A  40
TYR A  41
None
1.14A 1l7xB-1nogA:
undetectable
1l7xB-1nogA:
12.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BCR_A_AZZA940_1
(GLYCOGEN
PHOSPHORYLASE,
MUSCLE FORM)
1nog CONSERVED
HYPOTHETICAL PROTEIN
TA0546

(Thermoplasma
acidophilum)
4 / 5 PHE A  38
ALA A  42
GLY A  40
TYR A  41
None
1.15A 3bcrA-1nogA:
undetectable
3bcrA-1nogA:
13.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DD1_B_CFFB903_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)
1nog CONSERVED
HYPOTHETICAL PROTEIN
TA0546

(Thermoplasma
acidophilum)
4 / 6 PHE A  38
ALA A  42
GLY A  40
TYR A  41
None
1.09A 3dd1B-1nogA:
undetectable
3dd1B-1nogA:
12.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DDS_B_CFFB903_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)
1nog CONSERVED
HYPOTHETICAL PROTEIN
TA0546

(Thermoplasma
acidophilum)
4 / 6 PHE A  38
ALA A  42
GLY A  40
TYR A  41
None
1.14A 3ddsB-1nogA:
1.0
3ddsB-1nogA:
12.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DDW_A_CFFA903_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)
1nog CONSERVED
HYPOTHETICAL PROTEIN
TA0546

(Thermoplasma
acidophilum)
4 / 6 PHE A  38
ALA A  42
GLY A  40
TYR A  41
None
1.15A 3ddwA-1nogA:
undetectable
3ddwA-1nogA:
12.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DDW_B_CFFB903_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)
1nog CONSERVED
HYPOTHETICAL PROTEIN
TA0546

(Thermoplasma
acidophilum)
4 / 6 PHE A  38
ALA A  42
GLY A  40
TYR A  41
None
1.15A 3ddwB-1nogA:
undetectable
3ddwB-1nogA:
12.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WIP_G_ACTG306_0
(ACETYLCHOLINE-BINDIN
G PROTEIN)
1nog CONSERVED
HYPOTHETICAL PROTEIN
TA0546

(Thermoplasma
acidophilum)
3 / 3 ARG A 163
ARG A  89
ASP A  49
None
0.99A 3wipG-1nogA:
undetectable
3wipH-1nogA:
undetectable
3wipG-1nogA:
23.01
3wipH-1nogA:
23.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ODR_A_FK5A201_1
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
SLYD,
PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP1A CHIMERA)
1nog CONSERVED
HYPOTHETICAL PROTEIN
TA0546

(Thermoplasma
acidophilum)
5 / 12 LEU A 115
LEU A  35
LEU A 149
ILE A 152
ILE A  51
None
0.97A 4odrA-1nogA:
undetectable
4odrB-1nogA:
undetectable
4odrA-1nogA:
21.11
4odrB-1nogA:
21.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XV7_A_EMHA705_1
(SERINE-ARGININE (SR)
PROTEIN KINASE 1)
1nog CONSERVED
HYPOTHETICAL PROTEIN
TA0546

(Thermoplasma
acidophilum)
5 / 12 GLY A 108
ALA A 157
PHE A 154
TYR A  41
LEU A  45
None
0.73A 5xv7A-1nogA:
undetectable
5xv7A-1nogA:
19.66