SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1nox'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FM6_A_9CRA501_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 1nox NADH OXIDASE
(Thermus
thermophilus) 		5 / 12 ILE A  36
ALA A  39
ALA A  40
VAL A  28
LEU A  83
 None
 0.99A 1fm6A-1noxA:
undetectable		 1fm6A-1noxA:
24.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FM9_A_9CRA201_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 1nox NADH OXIDASE
(Thermus
thermophilus) 		5 / 12 ILE A  36
ALA A  39
ALA A  40
VAL A  28
LEU A  83
 None
 0.98A 1fm9A-1noxA:
undetectable		 1fm9A-1noxA:
24.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ONI_E_BEZE509_0
(14.5 KDA
TRANSLATIONAL
INHIBITOR PROTEIN)		 1nox NADH OXIDASE
(Thermus
thermophilus) 		4 / 7 ILE A 177
PHE A  71
ARG A 164
ALA A  69
 None
 1.13A 1oniD-1noxA:
undetectable
1oniE-1noxA:
undetectable		 1oniD-1noxA:
22.38
1oniE-1noxA:
22.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B9M_A_SALA1200_1
(SERUM ALBUMIN)		 1nox NADH OXIDASE
(Thermus
thermophilus) 		4 / 5 ILE A 100
HIS A 101
ARG A 108
GLY A 103
 None
 1.11A 3b9mA-1noxA:
undetectable		 3b9mA-1noxA:
16.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OLS_B_ESTB600_1
(ESTROGEN RECEPTOR
BETA)		 1nox NADH OXIDASE
(Thermus
thermophilus) 		5 / 12 LEU A  37
ALA A  39
LEU A 146
LEU A 147
ILE A  54
 None
 1.12A 3olsB-1noxA:
undetectable		 3olsB-1noxA:
23.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HWK_A_BEZA301_0
(GLUTATHIONE-SPECIFIC
GAMMA-GLUTAMYLCYCLOT
RANSFERASE)		 1nox NADH OXIDASE
(Thermus
thermophilus) 		5 / 10 GLY A 184
TYR A  23
GLY A 153
SER A 154
LEU A 183
 None
 1.42A 5hwkA-1noxA:
undetectable		 5hwkA-1noxA:
24.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JQB_B_IBPB706_1
(ENVELOPE
GLYCOPROTEIN
1,ENVELOPE
GLYCOPROTEIN
1,ENVELOPE
GLYCOPROTEIN 1
ENVELOPE
GLYCOPROTEIN 2)		 1nox NADH OXIDASE
(Thermus
thermophilus) 		5 / 8 ALA A  40
LEU A 140
LEU A  85
LEU A 147
LEU A 144
 None
 1.40A 5jqbA-1noxA:
undetectable
5jqbB-1noxA:
undetectable		 5jqbA-1noxA:
21.36
5jqbB-1noxA:
23.01