SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1noz'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RS7_B_MTLB871_0
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 1noz DNA POLYMERASE
(Escherichia
virus
T4) 		4 / 8 ASN A 368
PHE A 367
ASN A  84
ASP A 363
 None
 1.32A 1rs7B-1nozA:
0.0		 1rs7B-1nozA:
22.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AVV_E_MK1E902_2
(POL POLYPROTEIN)		 1noz DNA POLYMERASE
(Escherichia
virus
T4) 		3 / 3 ASP A 363
ILE A  91
VAL A 341
 None
 0.67A 2avvD-1nozA:
undetectable		 2avvD-1nozA:
15.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BL9_A_CP6A1240_1
(DIHYDROFOLATE
REDUCTASE-THYMIDYLAT
E SYNTHASE)		 1noz DNA POLYMERASE
(Escherichia
virus
T4) 		5 / 12 ILE A 130
ALA A 126
MET A 224
ILE A 215
ILE A 113
 None
 1.05A 2bl9A-1nozA:
undetectable		 2bl9A-1nozA:
20.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DU8_J_BEZJ3352_0
(D-AMINO-ACID OXIDASE)		 1noz DNA POLYMERASE
(Escherichia
virus
T4) 		4 / 5 TYR A  95
TYR A   5
ILE A   8
GLY A  96
 None
 1.27A 2du8J-1nozA:
undetectable		 2du8J-1nozA:
21.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A25_A_SAMA279_1
(UNCHARACTERIZED
PROTEIN PH0793)		 1noz DNA POLYMERASE
(Escherichia
virus
T4) 		3 / 3 MET A 356
GLU A 216
ASP A 219
 None
 1.08A 3a25A-1nozA:
undetectable		 3a25A-1nozA:
21.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KP6_B_SALB3006_1
(TRANSCRIPTIONAL
REGULATOR TCAR)		 1noz DNA POLYMERASE
(Escherichia
virus
T4) 		4 / 6 ASN A  23
ILE A  20
GLU A  22
LYS A   2
 None
 1.32A 3kp6A-1nozA:
0.3
3kp6B-1nozA:
0.0		 3kp6A-1nozA:
16.84
3kp6B-1nozA:
16.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N62_A_MTLA870_0
(NITRIC OXIDE
SYNTHASE)		 1noz DNA POLYMERASE
(Escherichia
virus
T4) 		4 / 8 ASN A 368
PHE A 367
ASN A  84
ASP A 363
 None
 1.26A 3n62A-1nozA:
0.0		 3n62A-1nozA:
23.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N62_B_MTLB870_0
(NITRIC OXIDE
SYNTHASE)		 1noz DNA POLYMERASE
(Escherichia
virus
T4) 		4 / 8 ASN A 368
PHE A 367
ASN A  84
ASP A 363
 None
 1.31A 3n62B-1nozA:
0.0		 3n62B-1nozA:
23.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PGL_A_RZXA257_1
(CARBOXY-TERMINAL
DOMAIN RNA
POLYMERASE II
POLYPEPTIDE A SMALL
PHOSPHATASE 1)		 1noz DNA POLYMERASE
(Escherichia
virus
T4) 		4 / 7 PHE A 352
VAL A 106
ILE A   6
TYR A 101
 None
 0.96A 3pglA-1nozA:
undetectable		 3pglA-1nozA:
18.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PWW_A_ROCA1001_1
(ENDOTHIAPEPSIN)		 1noz DNA POLYMERASE
(Escherichia
virus
T4) 		5 / 12 ILE A 223
ASP A 219
LEU A 201
THR A 134
ILE A 322
 None
 1.02A 3pwwA-1nozA:
undetectable		 3pwwA-1nozA:
20.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L4D_A_CAMA503_0
(CAMPHOR
5-MONOOXYGENASE)		 1noz DNA POLYMERASE
(Escherichia
virus
T4) 		4 / 8 THR A 211
LEU A 287
VAL A 328
ASP A 219
 None
 1.15A 4l4dA-1nozA:
0.0		 4l4dA-1nozA:
22.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OKB_A_198A1002_2
(ANDROGEN RECEPTOR)		 1noz DNA POLYMERASE
(Escherichia
virus
T4) 		4 / 6 ASN A 110
MET A 356
LEU A 273
VAL A 290
 None
 1.17A 4okbA-1nozA:
undetectable		 4okbA-1nozA:
19.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CSW_A_P06A801_2
(SERINE/THREONINE-PRO
TEIN KINASE B-RAF)		 1noz DNA POLYMERASE
(Escherichia
virus
T4) 		3 / 3 PHE A 352
ILE A 209
ASP A 269
 None
 0.67A 5cswA-1nozA:
undetectable		 5cswA-1nozA:
21.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CSW_B_P06B801_2
(SERINE/THREONINE-PRO
TEIN KINASE B-RAF)		 1noz DNA POLYMERASE
(Escherichia
virus
T4) 		3 / 3 PHE A 352
ILE A 209
ASP A 269
 None
 0.71A 5cswB-1nozA:
undetectable		 5cswB-1nozA:
21.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GWX_A_SAMA301_1
(GLYCINE SARCOSINE
N-METHYLTRANSFERASE)		 1noz DNA POLYMERASE
(Escherichia
virus
T4) 		3 / 3 ARG A 238
ASN A 200
ASP A 193
 None
 0.76A 5gwxA-1nozA:
undetectable		 5gwxA-1nozA:
20.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HI2_A_BAXA801_2
(SERINE/THREONINE-PRO
TEIN KINASE B-RAF)		 1noz DNA POLYMERASE
(Escherichia
virus
T4) 		5 / 8 ILE A 338
VAL A 145
ILE A 318
ILE A 323
ASP A 112
 None
 1.41A 5hi2A-1nozA:
undetectable		 5hi2A-1nozA:
22.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IH0_A_ERYA404_1
(MACROLIDE
2'-PHOSPHOTRANSFERAS
E II)		 1noz DNA POLYMERASE
(Escherichia
virus
T4) 		4 / 6 TYR A 198
ASP A 137
HIS A 135
ILE A 184
 None
 1.23A 5ih0A-1nozA:
0.3		 5ih0A-1nozA:
22.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UTU_H_ADNH503_2
(ADENOSYLHOMOCYSTEINA
SE)		 1noz DNA POLYMERASE
(Escherichia
virus
T4) 		4 / 5 THR A 280
GLU A 294
THR A 295
LEU A 287
 None
 1.25A 5utuH-1nozA:
undetectable		 5utuH-1nozA:
21.15