SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1np7'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1D8C_A_SORA4000_0
(MALATE SYNTHASE G)		 1np7 DNA PHOTOLYASE
(Synechocystis
sp.
PCC
6803) 		3 / 3 GLN A 419
HIS A 444
PRO A 423
 None
 0.90A 1d8cA-1np7A:
undetectable		 1d8cA-1np7A:
21.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GSF_A_EAAA223_1
(GLUTATHIONE
TRANSFERASE A1-1)		 1np7 DNA PHOTOLYASE
(Synechocystis
sp.
PCC
6803) 		4 / 8 PHE A 295
ARG A 293
VAL A 110
PHE A 296
 None
None
None
FAD  A 500 (-4.7A)
 1.20A 1gsfA-1np7A:
0.0		 1gsfA-1np7A:
18.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GSF_B_EAAB223_1
(GLUTATHIONE
TRANSFERASE A1-1)		 1np7 DNA PHOTOLYASE
(Synechocystis
sp.
PCC
6803) 		4 / 8 PHE A 295
ARG A 293
VAL A 110
PHE A 296
 None
None
None
FAD  A 500 (-4.7A)
 1.20A 1gsfB-1np7A:
0.0		 1gsfB-1np7A:
18.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GSF_D_EAAD223_1
(GLUTATHIONE
TRANSFERASE A1-1)		 1np7 DNA PHOTOLYASE
(Synechocystis
sp.
PCC
6803) 		4 / 8 PHE A 295
ARG A 293
VAL A 110
PHE A 296
 None
None
None
FAD  A 500 (-4.7A)
 1.20A 1gsfD-1np7A:
0.0		 1gsfD-1np7A:
18.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KB9_A_PCFA514_0
(CYTOCHROME B
CYTOCHROME C1, HEME
PROTEIN
UBIQUINOL-CYTOCHROME
C REDUCTASE COMPLEX
CORE PROTEIN I
UBIQUINOL-CYTOCHROME
C REDUCTASE
IRON-SULFUR SUBUNIT)		 1np7 DNA PHOTOLYASE
(Synechocystis
sp.
PCC
6803) 		4 / 8 SER A 475
ILE A 371
VAL A 340
MET A 344
 None
 1.13A 1kb9A-1np7A:
0.0
1kb9C-1np7A:
0.0
1kb9D-1np7A:
0.0
1kb9E-1np7A:
undetectable		 1kb9A-1np7A:
22.35
1kb9C-1np7A:
20.39
1kb9D-1np7A:
18.51
1kb9E-1np7A:
16.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MAA_B_DMEB996_1
(ACETYLCHOLINESTERASE)		 1np7 DNA PHOTOLYASE
(Synechocystis
sp.
PCC
6803) 		4 / 6 TYR A 427
GLU A 434
ILE A 414
GLY A 357
 None
 0.90A 1maaB-1np7A:
undetectable
1maaD-1np7A:
undetectable		 1maaB-1np7A:
22.08
1maaD-1np7A:
22.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XZX_X_T3X500_2
(THYROID HORMONE
RECEPTOR BETA-1)		 1np7 DNA PHOTOLYASE
(Synechocystis
sp.
PCC
6803) 		3 / 3 PHE A  12
ARG A  59
ASN A  14
 None
 0.89A 1xzxX-1np7A:
undetectable		 1xzxX-1np7A:
21.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q63_A_1UNA1001_2
(PROTEASE RETROPEPSIN)		 1np7 DNA PHOTOLYASE
(Synechocystis
sp.
PCC
6803) 		3 / 3 ARG A 331
ASN A 360
THR A 335
 None
 0.86A 2q63A-1np7A:
0.0		 2q63A-1np7A:
11.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q6K_A_ADNA699_1
(CHLORINASE)		 1np7 DNA PHOTOLYASE
(Synechocystis
sp.
PCC
6803) 		4 / 7 PHE A 198
TYR A  38
PRO A 194
THR A  84
 None
 1.33A 2q6kA-1np7A:
undetectable		 2q6kA-1np7A:
21.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJW_F_SVRF509_2
(PHOSPHOLIPASE A2)		 1np7 DNA PHOTOLYASE
(Synechocystis
sp.
PCC
6803) 		4 / 8 TYR A 236
PRO A 254
PHE A  62
TRP A 255
 FAD  A 500 (-4.5A)
None
None
None
 1.36A 3bjwD-1np7A:
undetectable		 3bjwD-1np7A:
13.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CZH_A_D2VA602_2
(CYTOCHROME P450 2R1)		 1np7 DNA PHOTOLYASE
(Synechocystis
sp.
PCC
6803) 		3 / 3 LEU A 233
GLU A 269
ILE A 266
 None
 0.53A 3czhA-1np7A:
0.0		 3czhA-1np7A:
22.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ZJQ_A_NCAA300_0
(PROTOGLOBIN)		 1np7 DNA PHOTOLYASE
(Synechocystis
sp.
PCC
6803) 		4 / 7 TYR A 337
VAL A 340
VAL A 470
PHE A 472
 None
 0.90A 3zjqA-1np7A:
undetectable		 3zjqA-1np7A:
19.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ZJQ_B_NCAB300_0
(PROTOGLOBIN)		 1np7 DNA PHOTOLYASE
(Synechocystis
sp.
PCC
6803) 		4 / 7 TYR A 337
VAL A 340
VAL A 470
PHE A 472
 None
 0.88A 3zjqB-1np7A:
undetectable		 3zjqB-1np7A:
19.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AE1_B_NCAB1536_0
(DIPHTHERIA TOXIN)		 1np7 DNA PHOTOLYASE
(Synechocystis
sp.
PCC
6803) 		4 / 5 HIS A 107
GLY A 137
TYR A 106
GLU A 118
 None
 1.32A 4ae1B-1np7A:
undetectable		 4ae1B-1np7A:
22.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4F93_B_SANB3004_1
(U5 SMALL NUCLEAR
RIBONUCLEOPROTEIN
200 KDA HELICASE)		 1np7 DNA PHOTOLYASE
(Synechocystis
sp.
PCC
6803) 		4 / 8 GLU A 328
GLN A 334
GLY A 333
SER A 332
 None
 0.72A 4f93B-1np7A:
0.0		 4f93B-1np7A:
15.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L3G_F_ACTF401_0
(METHYLAMINE
DEHYDROGENASE HEAVY
CHAIN)		 1np7 DNA PHOTOLYASE
(Synechocystis
sp.
PCC
6803) 		3 / 3 ARG A 207
LEU A 349
GLU A 346
 None
 0.66A 4l3gF-1np7A:
undetectable		 4l3gF-1np7A:
22.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MM6_A_29EA603_1
(TRANSPORTER)		 1np7 DNA PHOTOLYASE
(Synechocystis
sp.
PCC
6803) 		5 / 12 TYR A 398
ALA A 300
TYR A 303
PHE A 295
GLY A 394
 None
 1.12A 4mm6A-1np7A:
0.1		 4mm6A-1np7A:
23.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MMD_A_29EA603_1
(TRANSPORTER)		 1np7 DNA PHOTOLYASE
(Synechocystis
sp.
PCC
6803) 		5 / 10 TYR A 398
ALA A 300
TYR A 303
PHE A 295
GLY A 394
 None
 1.15A 4mmdA-1np7A:
undetectable		 4mmdA-1np7A:
22.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MMD_B_29EB603_1
(TRANSPORTER)		 1np7 DNA PHOTOLYASE
(Synechocystis
sp.
PCC
6803) 		5 / 12 TYR A 398
ALA A 300
TYR A 303
PHE A 295
GLY A 394
 None
 1.09A 4mmdB-1np7A:
0.0		 4mmdB-1np7A:
22.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RMJ_A_NCAA402_0
(NAD-DEPENDENT
PROTEIN DEACETYLASE
SIRTUIN-2)		 1np7 DNA PHOTOLYASE
(Synechocystis
sp.
PCC
6803) 		4 / 7 LEU A 125
LEU A   9
ASN A 100
ILE A  99
 None
 0.85A 4rmjA-1np7A:
undetectable		 4rmjA-1np7A:
21.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5E26_C_PAUC602_0
(PANTOTHENATE KINASE
2, MITOCHONDRIAL)		 1np7 DNA PHOTOLYASE
(Synechocystis
sp.
PCC
6803) 		4 / 7 GLU A 109
GLY A 259
SER A 138
ALA A 257
 None
 0.88A 5e26C-1np7A:
undetectable
5e26D-1np7A:
undetectable		 5e26C-1np7A:
22.03
5e26D-1np7A:
22.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5E26_D_PAUD601_0
(PANTOTHENATE KINASE
2, MITOCHONDRIAL)		 1np7 DNA PHOTOLYASE
(Synechocystis
sp.
PCC
6803) 		4 / 8 ALA A 257
GLU A 109
GLY A 259
SER A 138
 None
 0.88A 5e26C-1np7A:
undetectable
5e26D-1np7A:
undetectable		 5e26C-1np7A:
22.03
5e26D-1np7A:
22.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LRB_A_ACRA1003_1
(ALPHA-1,4 GLUCAN
PHOSPHORYLASE)		 1np7 DNA PHOTOLYASE
(Synechocystis
sp.
PCC
6803) 		4 / 6 GLU A 346
THR A 426
TYR A 427
TYR A 248
 None
 1.40A 5lrbA-1np7A:
1.4		 5lrbA-1np7A:
18.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VCE_A_RITA602_2
(CYTOCHROME P450 3A4)		 1np7 DNA PHOTOLYASE
(Synechocystis
sp.
PCC
6803) 		4 / 6 ARG A 161
PHE A 296
PHE A 298
THR A 139
 None
FAD  A 500 (-4.7A)
None
None
 1.09A 5vceA-1np7A:
0.0		 5vceA-1np7A:
24.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X23_A_LSNA502_2
(CYTOCHROME P450 2C9)		 1np7 DNA PHOTOLYASE
(Synechocystis
sp.
PCC
6803) 		3 / 3 LEU A 307
VAL A 389
ASP A 388
 None
 0.59A 5x23A-1np7A:
0.0		 5x23A-1np7A:
20.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X2T_I_PEMI202_1
(HEMOGLOBIN SUBUNIT
ALPHA
HEMOGLOBIN SUBUNIT
BETA)		 1np7 DNA PHOTOLYASE
(Synechocystis
sp.
PCC
6803) 		4 / 8 PRO A 143
THR A 139
ALA A 300
TRP A 136
 None
 0.95A 5x2tI-1np7A:
undetectable
5x2tJ-1np7A:
undetectable
5x2tK-1np7A:
undetectable
5x2tL-1np7A:
undetectable		 5x2tI-1np7A:
13.42
5x2tJ-1np7A:
15.32
5x2tK-1np7A:
13.42
5x2tL-1np7A:
15.32