SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1np8'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AOD_A_MIYA2001_1
(ACRIFLAVINE
RESISTANCE PROTEIN B)		 1np8 CALCIUM-DEPENDENT
PROTEASE, SMALL
SUBUNIT
(Rattus
norvegicus) 		4 / 8 PHE A 114
GLY A 112
ILE A  93
ALA A 117
 None
 0.93A 3aodA-1np8A:
undetectable		 3aodA-1np8A:
9.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QT0_A_486A4_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 1np8 CALCIUM-DEPENDENT
PROTEASE, SMALL
SUBUNIT
(Rattus
norvegicus) 		5 / 12 CYH A 148
ALA A 117
LEU A 110
ILE A 125
MET A 128
 None
 1.21A 3qt0A-1np8A:
undetectable		 3qt0A-1np8A:
20.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RTB_A_SAMA501_0
(HYDG PROTEIN)		 1np8 CALCIUM-DEPENDENT
PROTEASE, SMALL
SUBUNIT
(Rattus
norvegicus) 		5 / 12 CYH A  60
VAL A  44
LEU A  83
LEU A  75
ALA A  33
 None
 1.33A 4rtbA-1np8A:
undetectable		 4rtbA-1np8A:
17.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XMF_A_HSMA202_1
(NITROPHORIN-7)		 1np8 CALCIUM-DEPENDENT
PROTEASE, SMALL
SUBUNIT
(Rattus
norvegicus) 		3 / 3 ASP A  70
LEU A  75
GLY A  76
 CD  A 700 (-2.7A)
None
None
 0.56A 4xmfA-1np8A:
undetectable		 4xmfA-1np8A:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6F88_A_STRA502_1
(CYTOCHROME P450
CYP260A1)		 1np8 CALCIUM-DEPENDENT
PROTEASE, SMALL
SUBUNIT
(Rattus
norvegicus) 		4 / 6 PHE A  21
ALA A  25
SER A  32
THR A  72
 None
CD  A 703 (-4.4A)
CD  A 703 ( 4.8A)
CD  A 700 (-3.0A)
 0.85A 6f88A-1np8A:
undetectable		 6f88A-1np8A:
16.15