SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1nq3'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2O4S_A_AB1A400_2 (PROTEASE)	1nq3	14.3 KDA PERCHLORIC ACID SOLUBLE PROTEIN (Capra hircus)	5 / 12	GLY A 70 ALA A 69 ILE A 65 GLY A 63 ILE A 31	None	0.91A	2o4sB-1nq3A: undetectable	2o4sB-1nq3A: 23.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2R5Q_D_1UND900_2 (PROTEASE)	1nq3	14.3 KDA PERCHLORIC ACID SOLUBLE PROTEIN (Capra hircus)	5 / 10	GLY A 70 ALA A 69 ILE A 65 GLY A 63 ILE A 31	None	0.90A	2r5qD-1nq3A: undetectable	2r5qD-1nq3A: 20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4RRW_A_LURA705_1 (PROSTAGLANDIN G/H SYNTHASE 2)	1nq3	14.3 KDA PERCHLORIC ACID SOLUBLE PROTEIN (Capra hircus)	5 / 12	VAL A 81 LEU A 83 VAL A 51 ALA A 55 LEU A 59	None	1.15A	4rrwA-1nq3A: undetectable	4rrwA-1nq3A: 13.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4RRW_B_LURB705_1 (PROSTAGLANDIN G/H SYNTHASE 2)	1nq3	14.3 KDA PERCHLORIC ACID SOLUBLE PROTEIN (Capra hircus)	5 / 12	VAL A 81 LEU A 83 VAL A 51 ALA A 55 LEU A 59	None	1.16A	4rrwB-1nq3A: undetectable	4rrwB-1nq3A: 13.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4RRZ_A_LURA705_1 (PROSTAGLANDIN G/H SYNTHASE 2)	1nq3	14.3 KDA PERCHLORIC ACID SOLUBLE PROTEIN (Capra hircus)	5 / 12	VAL A 81 LEU A 83 VAL A 51 ALA A 55 LEU A 59	None	1.15A	4rrzA-1nq3A: undetectable	4rrzA-1nq3A: 13.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4RRZ_B_LURB705_1 (PROSTAGLANDIN G/H SYNTHASE 2)	1nq3	14.3 KDA PERCHLORIC ACID SOLUBLE PROTEIN (Capra hircus)	5 / 12	VAL A 81 LEU A 83 VAL A 51 ALA A 55 LEU A 59	None	1.16A	4rrzB-1nq3A: undetectable	4rrzB-1nq3A: 13.23

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["2O4S_A_AB1A400_2","PROTEASE;PROTEASE","1nq3","14.3 KDA PERCHLORIC ACID SOLUBLE PROTEIN","Capra hircus",5,"GLY A  70;ALA A  69;ILE A  65;GLY A  63;ILE A  31","None","0.91A","2o4sB-1nq3A:undetectable","2o4sB-1nq3A:23.45"],["2R5Q_D_1UND900_2","PROTEASE","1nq3","14.3 KDA PERCHLORIC ACID SOLUBLE PROTEIN","Capra hircus",5,"GLY A  70;ALA A  69;ILE A  65;GLY A  63;ILE A  31","None","0.90A","2r5qD-1nq3A:undetectable","2r5qD-1nq3A:20.00"],["4RRW_A_LURA705_1","PROSTAGLANDIN G\/H SYNTHASE 2","1nq3","14.3 KDA PERCHLORIC ACID SOLUBLE PROTEIN","Capra hircus",5,"VAL A  81;LEU A  83;VAL A  51;ALA A  55;LEU A  59","None","1.15A","4rrwA-1nq3A:undetectable","4rrwA-1nq3A:13.23"],["4RRW_B_LURB705_1","PROSTAGLANDIN G\/H SYNTHASE 2","1nq3","14.3 KDA PERCHLORIC ACID SOLUBLE PROTEIN","Capra hircus",5,"VAL A  81;LEU A  83;VAL A  51;ALA A  55;LEU A  59","None","1.16A","4rrwB-1nq3A:undetectable","4rrwB-1nq3A:13.23"],["4RRZ_A_LURA705_1","PROSTAGLANDIN G\/H SYNTHASE 2","1nq3","14.3 KDA PERCHLORIC ACID SOLUBLE PROTEIN","Capra hircus",5,"VAL A  81;LEU A  83;VAL A  51;ALA A  55;LEU A  59","None","1.15A","4rrzA-1nq3A:undetectable","4rrzA-1nq3A:13.23"],["4RRZ_B_LURB705_1","PROSTAGLANDIN G\/H SYNTHASE 2","1nq3","14.3 KDA PERCHLORIC ACID SOLUBLE PROTEIN","Capra hircus",5,"VAL A  81;LEU A  83;VAL A  51;ALA A  55;LEU A  59","None","1.16A","4rrzB-1nq3A:undetectable","4rrzB-1nq3A:13.23"]]