SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1nqb'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FBM_B_RTLB951_0
(PROTEIN (CARTILAGE
OLIGOMERIC MATRIX
PROTEIN))		 1nqb SINGLE-CHAIN
ANTIBODY FRAGMENT
(Mus
musculus) 		4 / 4 THR A  87
LEU A  86
LEU A  20
GLN A   6
 None
 1.23A 1fbmA-1nqbA:
undetectable		 1fbmA-1nqbA:
8.87
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2PCP_C_1PCC212_1
(IMMUNOGLOBULIN)		 1nqb SINGLE-CHAIN
ANTIBODY FRAGMENT
(Mus
musculus) 		5 / 10 HIS A 151
TYR A 157
PHE A 214
GLY A 216
TYR A 221
 None
 0.41A 2pcpC-1nqbA:
22.4
2pcpD-1nqbA:
21.2		 2pcpC-1nqbA:
37.00
2pcpD-1nqbA:
46.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q7K_A_TESA304_1
(ANDROGEN RECEPTOR)		 1nqb SINGLE-CHAIN
ANTIBODY FRAGMENT
(Mus
musculus) 		5 / 12 LEU A 198
GLN A 138
VAL A 203
LEU A 229
THR A 227
 None
 1.45A 2q7kA-1nqbA:
undetectable		 2q7kA-1nqbA:
21.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4M7K_H_ACTH302_0
(10H10 HEAVY CHAIN)		 1nqb SINGLE-CHAIN
ANTIBODY FRAGMENT
(Mus
musculus) 		4 / 5 VAL A   2
TYR A  27
ARG A  98
TYR A 109
 None
 0.28A 4m7kH-1nqbA:
22.3		 4m7kH-1nqbA:
49.22