SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1nqz'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2E5D_A_NCAA1501_0
(NICOTINAMIDE
PHOSPHORIBOSYLTRANSF
ERASE)		 1nqz COA PYROPHOSPHATASE
(MUTT/NUDIX FAMILY
PROTEIN)
(Deinococcus
radiodurans) 		4 / 7 ARG A  55
ASP A   6
ALA A  36
ASP A   9
 None
 0.98A 2e5dA-1nqzA:
undetectable
2e5dB-1nqzA:
undetectable		 2e5dA-1nqzA:
15.59
2e5dB-1nqzA:
15.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2E5D_B_NCAB1502_0
(NICOTINAMIDE
PHOSPHORIBOSYLTRANSF
ERASE)		 1nqz COA PYROPHOSPHATASE
(MUTT/NUDIX FAMILY
PROTEIN)
(Deinococcus
radiodurans) 		4 / 7 ASP A   9
ARG A  55
ASP A   6
ALA A  36
 None
 0.98A 2e5dA-1nqzA:
undetectable
2e5dB-1nqzA:
undetectable		 2e5dA-1nqzA:
15.59
2e5dB-1nqzA:
15.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F8D_A_BEZA1001_0
(HTH-TYPE
TRANSCRIPTIONAL
REGULATOR BENM)		 1nqz COA PYROPHOSPHATASE
(MUTT/NUDIX FAMILY
PROTEIN)
(Deinococcus
radiodurans) 		4 / 6 VAL A 107
SER A  21
ARG A 183
HIS A 186
 None
 1.22A 2f8dA-1nqzA:
0.0		 2f8dA-1nqzA:
22.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJW_B_SVRB512_1
(PHOSPHOLIPASE A2)		 1nqz COA PYROPHOSPHATASE
(MUTT/NUDIX FAMILY
PROTEIN)
(Deinococcus
radiodurans) 		4 / 5 VAL A  50
THR A 181
THR A 143
ARG A  49
 None
 1.19A 3bjwA-1nqzA:
undetectable		 3bjwA-1nqzA:
18.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJW_F_SVRF509_1
(PHOSPHOLIPASE A2)		 1nqz COA PYROPHOSPHATASE
(MUTT/NUDIX FAMILY
PROTEIN)
(Deinococcus
radiodurans) 		4 / 5 VAL A  50
THR A 181
THR A 143
ARG A  49
 None
 1.22A 3bjwC-1nqzA:
undetectable		 3bjwC-1nqzA:
18.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DH0_B_SAMB300_0
(SAM DEPENDENT
METHYLTRANSFERASE)		 1nqz COA PYROPHOSPHATASE
(MUTT/NUDIX FAMILY
PROTEIN)
(Deinococcus
radiodurans) 		5 / 12 LEU A   8
GLY A  70
VAL A  40
THR A 181
LEU A 185
 None
 1.10A 3dh0B-1nqzA:
undetectable		 3dh0B-1nqzA:
22.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EL9_A_DR7A100_1
(PROTEASE)		 1nqz COA PYROPHOSPHATASE
(MUTT/NUDIX FAMILY
PROTEIN)
(Deinococcus
radiodurans) 		4 / 8 ASP A  14
ALA A  17
GLY A 112
PRO A   7
 None
 0.86A 3el9A-1nqzA:
undetectable		 3el9A-1nqzA:
18.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MEC_A_65BA561_0
(P66 REVERSE
TRANSCRIPTASE)		 1nqz COA PYROPHOSPHATASE
(MUTT/NUDIX FAMILY
PROTEIN)
(Deinococcus
radiodurans) 		5 / 12 VAL A  40
VAL A  98
GLY A 120
PHE A  68
PRO A 117
 None
 1.28A 3mecA-1nqzA:
undetectable		 3mecA-1nqzA:
16.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PBH_A_BEZA401_0
(TRAP DICARBOXYLATE
TRANSPORTER, DCTP
SUBUNIT, PUTATIVE)		 1nqz COA PYROPHOSPHATASE
(MUTT/NUDIX FAMILY
PROTEIN)
(Deinococcus
radiodurans) 		5 / 12 ILE A 139
THR A 141
ALA A  41
LEU A 130
LEU A  93
 None
 1.23A 4pbhA-1nqzA:
0.0		 4pbhA-1nqzA:
22.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RTB_A_SAMA501_0
(HYDG PROTEIN)		 1nqz COA PYROPHOSPHATASE
(MUTT/NUDIX FAMILY
PROTEIN)
(Deinococcus
radiodurans) 		5 / 12 TYR A 170
VAL A 107
LEU A 189
LEU A 147
PHE A  68
 None
 1.18A 4rtbA-1nqzA:
undetectable		 4rtbA-1nqzA:
18.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HHJ_B_GLYB404_0
(RETRON-TYPE REVERSE
TRANSCRIPTASE)		 1nqz COA PYROPHOSPHATASE
(MUTT/NUDIX FAMILY
PROTEIN)
(Deinococcus
radiodurans) 		4 / 4 GLN A  12
ALA A  67
GLN A  65
THR A  53
 None
 1.16A 5hhjB-1nqzA:
undetectable		 5hhjB-1nqzA:
20.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LJE_A_RTLA201_0
(RETINOL-BINDING
PROTEIN 1)		 1nqz COA PYROPHOSPHATASE
(MUTT/NUDIX FAMILY
PROTEIN)
(Deinococcus
radiodurans) 		5 / 12 LEU A 127
LEU A 130
LEU A 188
ILE A 122
LEU A 144
 None
 1.02A 5ljeA-1nqzA:
0.0		 5ljeA-1nqzA:
21.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M50_E_TA1E502_1
(TUBULIN BETA-2B
CHAIN)		 1nqz COA PYROPHOSPHATASE
(MUTT/NUDIX FAMILY
PROTEIN)
(Deinococcus
radiodurans) 		5 / 12 VAL A 184
ASP A 187
LEU A  73
THR A  78
GLY A 102
 None
 0.82A 5m50E-1nqzA:
undetectable		 5m50E-1nqzA:
18.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UUN_B_ACTB307_0
(GLUTATHIONE
S-TRANSFERASE-LIKE
PROTEIN)		 1nqz COA PYROPHOSPHATASE
(MUTT/NUDIX FAMILY
PROTEIN)
(Deinococcus
radiodurans) 		3 / 3 LEU A  93
ALA A  92
LEU A  51
 None
 0.49A 5uunB-1nqzA:
undetectable		 5uunB-1nqzA:
21.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B0C_D_TA1D502_1
(TUBULIN BETA CHAIN)		 1nqz COA PYROPHOSPHATASE
(MUTT/NUDIX FAMILY
PROTEIN)
(Deinococcus
radiodurans) 		5 / 12 VAL A 107
LEU A 185
LEU A  52
THR A  53
GLY A  71
 None
 0.87A 6b0cD-1nqzA:
undetectable		 6b0cD-1nqzA:
18.13