SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1nrk'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1D1V_A_H4BA700_1
(BOVINE ENDOTHELIAL
NITRIC OXIDE
SYNTHASE HEME)		 1nrk YGFZ PROTEIN
(Escherichia
coli) 		4 / 6 VAL A 200
ARG A 160
TRP A  27
PHE A 154
 None
None
SO4  A 400 (-3.4A)
SO4  A 400 (-4.6A)
 1.35A 1d1vA-1nrkA:
0.0
1d1vB-1nrkA:
0.0		 1d1vA-1nrkA:
21.41
1d1vB-1nrkA:
21.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1D1W_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE)		 1nrk YGFZ PROTEIN
(Escherichia
coli) 		4 / 6 VAL A 200
ARG A 160
TRP A  27
PHE A 154
 None
None
SO4  A 400 (-3.4A)
SO4  A 400 (-4.6A)
 1.35A 1d1wA-1nrkA:
0.0
1d1wB-1nrkA:
0.0		 1d1wA-1nrkA:
21.41
1d1wB-1nrkA:
21.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1D1W_B_H4BB601_1
(NITRIC OXIDE
SYNTHASE)		 1nrk YGFZ PROTEIN
(Escherichia
coli) 		4 / 6 PHE A 154
VAL A 200
ARG A 160
TRP A  27
 SO4  A 400 (-4.6A)
None
None
SO4  A 400 (-3.4A)
 1.30A 1d1wA-1nrkA:
0.0
1d1wB-1nrkA:
0.0		 1d1wA-1nrkA:
21.41
1d1wB-1nrkA:
21.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DM8_A_H4BA1600_1
(NITRIC OXIDE
SYNTHASE)		 1nrk YGFZ PROTEIN
(Escherichia
coli) 		4 / 6 VAL A 200
ARG A 160
TRP A  27
PHE A 154
 None
None
SO4  A 400 (-3.4A)
SO4  A 400 (-4.6A)
 1.37A 1dm8A-1nrkA:
0.0
1dm8B-1nrkA:
0.0		 1dm8A-1nrkA:
21.41
1dm8B-1nrkA:
21.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DMI_B_BHSB2610_1
(NITRIC OXIDE
SYNTHASE)		 1nrk YGFZ PROTEIN
(Escherichia
coli) 		4 / 6 PHE A 154
VAL A 200
ARG A 160
TRP A  27
 SO4  A 400 (-4.6A)
None
None
SO4  A 400 (-3.4A)
 1.33A 1dmiA-1nrkA:
0.0
1dmiB-1nrkA:
0.0		 1dmiA-1nrkA:
21.41
1dmiB-1nrkA:
21.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FBM_B_RTLB951_0
(PROTEIN (CARTILAGE
OLIGOMERIC MATRIX
PROTEIN))		 1nrk YGFZ PROTEIN
(Escherichia
coli) 		4 / 4 THR A 278
LEU A 280
LEU A 190
GLN A 187
 None
 1.23A 1fbmA-1nrkA:
undetectable		 1fbmA-1nrkA:
10.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L2I_B_CCSB417_0
(ESTROGEN RECEPTOR)		 1nrk YGFZ PROTEIN
(Escherichia
coli) 		4 / 6 PRO A   8
GLU A 286
GLN A 187
LYS A 284
 None
 1.46A 1l2iB-1nrkA:
undetectable		 1l2iB-1nrkA:
22.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1M8E_B_H4BB903_1
(INDUCIBLE NITRIC
OXIDE SYNTHASE)		 1nrk YGFZ PROTEIN
(Escherichia
coli) 		3 / 3 ARG A 160
ILE A  85
TRP A  27
 None
SO4  A 400 ( 4.7A)
SO4  A 400 (-3.4A)
 1.12A 1m8eB-1nrkA:
0.0		 1m8eB-1nrkA:
21.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MX1_A_THAA1_1
(LIVER
CARBOXYLESTERASE I)		 1nrk YGFZ PROTEIN
(Escherichia
coli) 		5 / 11 LEU A 129
PHE A 133
GLY A 119
LEU A  24
LEU A 177
 None
 1.01A 1mx1A-1nrkA:
undetectable		 1mx1A-1nrkA:
22.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P6L_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE,
ENDOTHELIAL)		 1nrk YGFZ PROTEIN
(Escherichia
coli) 		4 / 6 VAL A 200
ARG A 160
TRP A  27
PHE A 154
 None
None
SO4  A 400 (-3.4A)
SO4  A 400 (-4.6A)
 1.34A 1p6lA-1nrkA:
0.0
1p6lB-1nrkA:
0.0		 1p6lA-1nrkA:
22.30
1p6lB-1nrkA:
22.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P6L_B_H4BB761_1
(NITRIC-OXIDE
SYNTHASE,
ENDOTHELIAL)		 1nrk YGFZ PROTEIN
(Escherichia
coli) 		4 / 6 PHE A 154
VAL A 200
ARG A 160
TRP A  27
 SO4  A 400 (-4.6A)
None
None
SO4  A 400 (-3.4A)
 1.30A 1p6lA-1nrkA:
0.0
1p6lB-1nrkA:
0.0		 1p6lA-1nrkA:
22.30
1p6lB-1nrkA:
22.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P6M_B_H4BB761_1
(NITRIC-OXIDE
SYNTHASE,
ENDOTHELIAL)		 1nrk YGFZ PROTEIN
(Escherichia
coli) 		4 / 6 PHE A 154
VAL A 200
ARG A 160
TRP A  27
 SO4  A 400 (-4.6A)
None
None
SO4  A 400 (-3.4A)
 1.35A 1p6mA-1nrkA:
0.0
1p6mB-1nrkA:
0.0		 1p6mA-1nrkA:
22.30
1p6mB-1nrkA:
22.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q2O_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE,
ENDOTHELIAL)		 1nrk YGFZ PROTEIN
(Escherichia
coli) 		4 / 6 VAL A 200
ARG A 160
TRP A  27
PHE A 154
 None
None
SO4  A 400 (-3.4A)
SO4  A 400 (-4.6A)
 1.34A 1q2oA-1nrkA:
0.0
1q2oB-1nrkA:
0.0		 1q2oA-1nrkA:
22.30
1q2oB-1nrkA:
22.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q2O_B_H4BB761_1
(NITRIC-OXIDE
SYNTHASE,
ENDOTHELIAL)		 1nrk YGFZ PROTEIN
(Escherichia
coli) 		4 / 6 PHE A 154
VAL A 200
ARG A 160
TRP A  27
 SO4  A 400 (-4.6A)
None
None
SO4  A 400 (-3.4A)
 1.30A 1q2oA-1nrkA:
0.0
1q2oB-1nrkA:
0.0		 1q2oA-1nrkA:
22.30
1q2oB-1nrkA:
22.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RS8_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE,
ENDOTHELIAL)		 1nrk YGFZ PROTEIN
(Escherichia
coli) 		4 / 6 VAL A 200
ARG A 160
TRP A  27
PHE A 154
 None
None
SO4  A 400 (-3.4A)
SO4  A 400 (-4.6A)
 1.34A 1rs8A-1nrkA:
0.0
1rs8B-1nrkA:
0.0		 1rs8A-1nrkA:
22.30
1rs8B-1nrkA:
22.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RS9_B_H4BB761_1
(NITRIC-OXIDE
SYNTHASE,
ENDOTHELIAL)		 1nrk YGFZ PROTEIN
(Escherichia
coli) 		4 / 6 PHE A 154
VAL A 200
ARG A 160
TRP A  27
 SO4  A 400 (-4.6A)
None
None
SO4  A 400 (-3.4A)
 1.32A 1rs9A-1nrkA:
0.0
1rs9B-1nrkA:
0.0		 1rs9A-1nrkA:
22.30
1rs9B-1nrkA:
22.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZZS_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE,
ENDOTHELIAL)		 1nrk YGFZ PROTEIN
(Escherichia
coli) 		4 / 6 VAL A 200
ARG A 160
TRP A  27
PHE A 154
 None
None
SO4  A 400 (-3.4A)
SO4  A 400 (-4.6A)
 1.33A 1zzsA-1nrkA:
0.0
1zzsB-1nrkA:
0.0		 1zzsA-1nrkA:
22.30
1zzsB-1nrkA:
22.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZZS_B_H4BB761_1
(NITRIC-OXIDE
SYNTHASE,
ENDOTHELIAL)		 1nrk YGFZ PROTEIN
(Escherichia
coli) 		4 / 6 PHE A 154
VAL A 200
ARG A 160
TRP A  27
 SO4  A 400 (-4.6A)
None
None
SO4  A 400 (-3.4A)
 1.32A 1zzsA-1nrkA:
0.0
1zzsB-1nrkA:
0.0		 1zzsA-1nrkA:
22.30
1zzsB-1nrkA:
22.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZZU_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 1nrk YGFZ PROTEIN
(Escherichia
coli) 		4 / 7 VAL A 200
ARG A 160
TRP A  27
PHE A 154
 None
None
SO4  A 400 (-3.4A)
SO4  A 400 (-4.6A)
 1.28A 1zzuA-1nrkA:
0.0
1zzuB-1nrkA:
0.0		 1zzuA-1nrkA:
21.02
1zzuB-1nrkA:
21.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AA6_A_STRA401_1
(MINERALOCORTICOID
RECEPTOR)		 1nrk YGFZ PROTEIN
(Escherichia
coli) 		5 / 12 LEU A 132
ASN A 131
LEU A 129
ALA A 128
LEU A  21
 None
 1.30A 2aa6A-1nrkA:
undetectable		 2aa6A-1nrkA:
22.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HX2_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE)		 1nrk YGFZ PROTEIN
(Escherichia
coli) 		4 / 6 VAL A 200
ARG A 160
TRP A  27
PHE A 154
 None
None
SO4  A 400 (-3.4A)
SO4  A 400 (-4.6A)
 1.33A 2hx2A-1nrkA:
0.0
2hx2B-1nrkA:
0.0		 2hx2A-1nrkA:
22.30
2hx2B-1nrkA:
22.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HX2_B_H4BB760_1
(NITRIC-OXIDE
SYNTHASE)		 1nrk YGFZ PROTEIN
(Escherichia
coli) 		4 / 6 PHE A 154
VAL A 200
ARG A 160
TRP A  27
 SO4  A 400 (-4.6A)
None
None
SO4  A 400 (-3.4A)
 1.35A 2hx2A-1nrkA:
0.0
2hx2B-1nrkA:
0.0		 2hx2A-1nrkA:
22.30
2hx2B-1nrkA:
22.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2J2P_E_SC2E1289_1
(FICOLIN-2)		 1nrk YGFZ PROTEIN
(Escherichia
coli) 		4 / 6 ASP A 112
ARG A 115
ASP A 166
ASP A  78
 None
 1.03A 2j2pE-1nrkA:
undetectable
2j2pF-1nrkA:
undetectable		 2j2pE-1nrkA:
22.29
2j2pF-1nrkA:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NSE_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE)		 1nrk YGFZ PROTEIN
(Escherichia
coli) 		4 / 6 VAL A 200
ARG A 160
TRP A  27
PHE A 154
 None
None
SO4  A 400 (-3.4A)
SO4  A 400 (-4.6A)
 1.35A 2nseA-1nrkA:
0.0
2nseB-1nrkA:
0.0		 2nseA-1nrkA:
21.41
2nseB-1nrkA:
21.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DQS_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 1nrk YGFZ PROTEIN
(Escherichia
coli) 		4 / 6 PHE A 154
VAL A 200
ARG A 160
TRP A  27
 SO4  A 400 (-4.6A)
None
None
SO4  A 400 (-3.4A)
 1.34A 3dqsA-1nrkA:
0.0
3dqsB-1nrkA:
0.0		 3dqsA-1nrkA:
22.30
3dqsB-1nrkA:
22.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DQT_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 1nrk YGFZ PROTEIN
(Escherichia
coli) 		4 / 7 PHE A 154
VAL A 200
ARG A 160
TRP A  27
 SO4  A 400 (-4.6A)
None
None
SO4  A 400 (-3.4A)
 1.35A 3dqtA-1nrkA:
undetectable
3dqtB-1nrkA:
undetectable		 3dqtA-1nrkA:
22.30
3dqtB-1nrkA:
22.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3E68_A_H4BA902_1
(NITRIC OXIDE
SYNTHASE, INDUCIBLE)		 1nrk YGFZ PROTEIN
(Escherichia
coli) 		3 / 3 ARG A 160
ILE A  85
TRP A  27
 None
SO4  A 400 ( 4.7A)
SO4  A 400 (-3.4A)
 1.06A 3e68A-1nrkA:
0.0		 3e68A-1nrkA:
21.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3E6T_B_H4BB902_1
(NITRIC OXIDE
SYNTHASE, INDUCIBLE)		 1nrk YGFZ PROTEIN
(Escherichia
coli) 		3 / 3 ARG A 160
ILE A  85
TRP A  27
 None
SO4  A 400 ( 4.7A)
SO4  A 400 (-3.4A)
 1.12A 3e6tB-1nrkA:
0.0		 3e6tB-1nrkA:
21.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EJ8_B_H4BB2902_1
(NITRIC OXIDE
SYNTHASE, INDUCIBLE)		 1nrk YGFZ PROTEIN
(Escherichia
coli) 		4 / 7 PHE A 154
ARG A 160
ILE A  85
TRP A  27
 SO4  A 400 (-4.6A)
None
SO4  A 400 ( 4.7A)
SO4  A 400 (-3.4A)
 1.33A 3ej8A-1nrkA:
0.0
3ej8B-1nrkA:
0.0		 3ej8A-1nrkA:
22.22
3ej8B-1nrkA:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JWW_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 1nrk YGFZ PROTEIN
(Escherichia
coli) 		4 / 5 VAL A 200
ARG A 160
TRP A  27
PHE A 154
 None
None
SO4  A 400 (-3.4A)
SO4  A 400 (-4.6A)
 1.28A 3jwwA-1nrkA:
0.0
3jwwB-1nrkA:
0.0		 3jwwA-1nrkA:
21.41
3jwwB-1nrkA:
21.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JWX_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 1nrk YGFZ PROTEIN
(Escherichia
coli) 		4 / 6 VAL A 200
ARG A 160
TRP A  27
PHE A 154
 None
None
SO4  A 400 (-3.4A)
SO4  A 400 (-4.6A)
 1.31A 3jwxA-1nrkA:
0.0
3jwxB-1nrkA:
0.0		 3jwxA-1nrkA:
21.41
3jwxB-1nrkA:
21.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JWX_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 1nrk YGFZ PROTEIN
(Escherichia
coli) 		4 / 6 PHE A 154
VAL A 200
ARG A 160
TRP A  27
 SO4  A 400 (-4.6A)
None
None
SO4  A 400 (-3.4A)
 1.28A 3jwxA-1nrkA:
0.0
3jwxB-1nrkA:
0.0		 3jwxA-1nrkA:
21.41
3jwxB-1nrkA:
21.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JWY_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 1nrk YGFZ PROTEIN
(Escherichia
coli) 		4 / 6 PHE A 154
VAL A 200
ARG A 160
TRP A  27
 SO4  A 400 (-4.6A)
None
None
SO4  A 400 (-3.4A)
 1.33A 3jwyA-1nrkA:
0.0
3jwyB-1nrkA:
0.0		 3jwyA-1nrkA:
21.41
3jwyB-1nrkA:
21.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JWZ_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 1nrk YGFZ PROTEIN
(Escherichia
coli) 		4 / 6 PHE A 154
VAL A 200
ARG A 160
TRP A  27
 SO4  A 400 (-4.6A)
None
None
SO4  A 400 (-3.4A)
 1.31A 3jwzA-1nrkA:
0.0
3jwzB-1nrkA:
0.0		 3jwzA-1nrkA:
21.41
3jwzB-1nrkA:
21.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JX3_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1nrk YGFZ PROTEIN
(Escherichia
coli) 		4 / 7 VAL A 200
ARG A 160
TRP A  27
PHE A 154
 None
None
SO4  A 400 (-3.4A)
SO4  A 400 (-4.6A)
 1.26A 3jx3A-1nrkA:
0.0
3jx3B-1nrkA:
0.0		 3jx3A-1nrkA:
20.92
3jx3B-1nrkA:
20.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JX5_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1nrk YGFZ PROTEIN
(Escherichia
coli) 		4 / 7 VAL A 200
ARG A 160
TRP A  27
PHE A 154
 None
None
SO4  A 400 (-3.4A)
SO4  A 400 (-4.6A)
 1.27A 3jx5A-1nrkA:
undetectable
3jx5B-1nrkA:
undetectable		 3jx5A-1nrkA:
20.92
3jx5B-1nrkA:
20.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JX6_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1nrk YGFZ PROTEIN
(Escherichia
coli) 		4 / 7 VAL A 200
ARG A 160
TRP A  27
PHE A 154
 None
None
SO4  A 400 (-3.4A)
SO4  A 400 (-4.6A)
 1.23A 3jx6A-1nrkA:
undetectable
3jx6B-1nrkA:
undetectable		 3jx6A-1nrkA:
20.92
3jx6B-1nrkA:
20.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MBG_A_ACTA207_0
(FAD-LINKED
SULFHYDRYL OXIDASE
ALR)		 1nrk YGFZ PROTEIN
(Escherichia
coli) 		4 / 7 LEU A  29
ASP A  78
THR A  31
ALA A  83
 None
 1.27A 3mbgA-1nrkA:
undetectable
3mbgB-1nrkA:
undetectable		 3mbgA-1nrkA:
16.92
3mbgB-1nrkA:
16.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N5P_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE)		 1nrk YGFZ PROTEIN
(Escherichia
coli) 		4 / 5 VAL A 200
ARG A 160
TRP A  27
PHE A 154
 None
None
SO4  A 400 (-3.4A)
SO4  A 400 (-4.6A)
 1.37A 3n5pA-1nrkA:
0.0
3n5pB-1nrkA:
0.0		 3n5pA-1nrkA:
21.41
3n5pB-1nrkA:
21.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N5R_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE)		 1nrk YGFZ PROTEIN
(Escherichia
coli) 		4 / 6 PHE A 154
VAL A 200
ARG A 160
TRP A  27
 SO4  A 400 (-4.6A)
None
None
SO4  A 400 (-3.4A)
 1.35A 3n5rA-1nrkA:
0.0
3n5rB-1nrkA:
0.0		 3n5rA-1nrkA:
21.41
3n5rB-1nrkA:
21.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N5S_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE)		 1nrk YGFZ PROTEIN
(Escherichia
coli) 		4 / 6 VAL A 200
ARG A 160
TRP A  27
PHE A 154
 None
None
SO4  A 400 (-3.4A)
SO4  A 400 (-4.6A)
 1.33A 3n5sA-1nrkA:
0.0
3n5sB-1nrkA:
0.0		 3n5sA-1nrkA:
21.41
3n5sB-1nrkA:
21.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N5S_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE)		 1nrk YGFZ PROTEIN
(Escherichia
coli) 		4 / 6 PHE A 154
VAL A 200
ARG A 160
TRP A  27
 SO4  A 400 (-4.6A)
None
None
SO4  A 400 (-3.4A)
 1.31A 3n5sA-1nrkA:
0.0
3n5sB-1nrkA:
0.0		 3n5sA-1nrkA:
21.41
3n5sB-1nrkA:
21.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N5T_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE)		 1nrk YGFZ PROTEIN
(Escherichia
coli) 		4 / 7 VAL A 200
ARG A 160
TRP A  27
PHE A 154
 None
None
SO4  A 400 (-3.4A)
SO4  A 400 (-4.6A)
 1.27A 3n5tA-1nrkA:
undetectable
3n5tB-1nrkA:
undetectable		 3n5tA-1nrkA:
21.41
3n5tB-1nrkA:
21.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N5T_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE)		 1nrk YGFZ PROTEIN
(Escherichia
coli) 		4 / 6 PHE A 154
VAL A 200
ARG A 160
TRP A  27
 SO4  A 400 (-4.6A)
None
None
SO4  A 400 (-3.4A)
 1.27A 3n5tA-1nrkA:
0.0
3n5tB-1nrkA:
0.0		 3n5tA-1nrkA:
21.41
3n5tB-1nrkA:
21.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N6E_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE)		 1nrk YGFZ PROTEIN
(Escherichia
coli) 		4 / 6 VAL A 200
ARG A 160
TRP A  27
PHE A 154
 None
None
SO4  A 400 (-3.4A)
SO4  A 400 (-4.6A)
 1.33A 3n6eA-1nrkA:
0.0
3n6eB-1nrkA:
0.0		 3n6eA-1nrkA:
21.63
3n6eB-1nrkA:
21.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N6E_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE)		 1nrk YGFZ PROTEIN
(Escherichia
coli) 		4 / 6 PHE A 154
VAL A 200
ARG A 160
TRP A  27
 SO4  A 400 (-4.6A)
None
None
SO4  A 400 (-3.4A)
 1.30A 3n6eA-1nrkA:
0.0
3n6eB-1nrkA:
0.0		 3n6eA-1nrkA:
21.63
3n6eB-1nrkA:
21.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N6F_A_H4BA600_1
('NITRIC OXIDE
SYNTHASE)		 1nrk YGFZ PROTEIN
(Escherichia
coli) 		4 / 6 VAL A 200
ARG A 160
TRP A  27
PHE A 154
 None
None
SO4  A 400 (-3.4A)
SO4  A 400 (-4.6A)
 1.33A 3n6fA-1nrkA:
0.0
3n6fB-1nrkA:
0.0		 3n6fA-1nrkA:
21.63
3n6fB-1nrkA:
21.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N6F_B_H4BB600_1
('NITRIC OXIDE
SYNTHASE)		 1nrk YGFZ PROTEIN
(Escherichia
coli) 		4 / 6 PHE A 154
VAL A 200
ARG A 160
TRP A  27
 SO4  A 400 (-4.6A)
None
None
SO4  A 400 (-3.4A)
 1.30A 3n6fA-1nrkA:
0.0
3n6fB-1nrkA:
0.0		 3n6fA-1nrkA:
21.63
3n6fB-1nrkA:
21.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N6G_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE)		 1nrk YGFZ PROTEIN
(Escherichia
coli) 		4 / 6 VAL A 200
ARG A 160
TRP A  27
PHE A 154
 None
None
SO4  A 400 (-3.4A)
SO4  A 400 (-4.6A)
 1.36A 3n6gA-1nrkA:
0.0
3n6gB-1nrkA:
0.0		 3n6gA-1nrkA:
21.63
3n6gB-1nrkA:
21.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N6G_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE)		 1nrk YGFZ PROTEIN
(Escherichia
coli) 		4 / 6 PHE A 154
VAL A 200
ARG A 160
TRP A  27
 SO4  A 400 (-4.6A)
None
None
SO4  A 400 (-3.4A)
 1.32A 3n6gA-1nrkA:
0.0
3n6gB-1nrkA:
0.0		 3n6gA-1nrkA:
21.63
3n6gB-1nrkA:
21.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLE_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 1nrk YGFZ PROTEIN
(Escherichia
coli) 		4 / 6 VAL A 200
ARG A 160
TRP A  27
PHE A 154
 None
None
SO4  A 400 (-3.4A)
SO4  A 400 (-4.6A)
 1.29A 3nleA-1nrkA:
0.0
3nleB-1nrkA:
0.0		 3nleA-1nrkA:
21.41
3nleB-1nrkA:
21.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLE_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 1nrk YGFZ PROTEIN
(Escherichia
coli) 		4 / 6 PHE A 154
VAL A 200
ARG A 160
TRP A  27
 SO4  A 400 (-4.6A)
None
None
SO4  A 400 (-3.4A)
 1.30A 3nleA-1nrkA:
0.0
3nleB-1nrkA:
0.0		 3nleA-1nrkA:
21.41
3nleB-1nrkA:
21.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLF_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 1nrk YGFZ PROTEIN
(Escherichia
coli) 		4 / 6 PHE A 154
VAL A 200
ARG A 160
TRP A  27
 SO4  A 400 (-4.6A)
None
None
SO4  A 400 (-3.4A)
 1.34A 3nlfA-1nrkA:
0.0
3nlfB-1nrkA:
0.0		 3nlfA-1nrkA:
21.41
3nlfB-1nrkA:
21.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLG_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 1nrk YGFZ PROTEIN
(Escherichia
coli) 		4 / 6 VAL A 200
ARG A 160
TRP A  27
PHE A 154
 None
None
SO4  A 400 (-3.4A)
SO4  A 400 (-4.6A)
 1.37A 3nlgA-1nrkA:
0.0
3nlgB-1nrkA:
0.0		 3nlgA-1nrkA:
21.41
3nlgB-1nrkA:
21.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLG_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 1nrk YGFZ PROTEIN
(Escherichia
coli) 		4 / 6 PHE A 154
VAL A 200
ARG A 160
TRP A  27
 SO4  A 400 (-4.6A)
None
None
SO4  A 400 (-3.4A)
 1.32A 3nlgA-1nrkA:
0.0
3nlgB-1nrkA:
0.0		 3nlgA-1nrkA:
21.41
3nlgB-1nrkA:
21.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLH_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 1nrk YGFZ PROTEIN
(Escherichia
coli) 		4 / 6 VAL A 200
ARG A 160
TRP A  27
PHE A 154
 None
None
SO4  A 400 (-3.4A)
SO4  A 400 (-4.6A)
 1.38A 3nlhA-1nrkA:
0.0
3nlhB-1nrkA:
0.0		 3nlhA-1nrkA:
21.63
3nlhB-1nrkA:
21.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLH_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 1nrk YGFZ PROTEIN
(Escherichia
coli) 		4 / 6 PHE A 154
VAL A 200
ARG A 160
TRP A  27
 SO4  A 400 (-4.6A)
None
None
SO4  A 400 (-3.4A)
 1.34A 3nlhA-1nrkA:
0.0
3nlhB-1nrkA:
0.0		 3nlhA-1nrkA:
21.63
3nlhB-1nrkA:
21.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLI_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 1nrk YGFZ PROTEIN
(Escherichia
coli) 		4 / 6 VAL A 200
ARG A 160
TRP A  27
PHE A 154
 None
None
SO4  A 400 (-3.4A)
SO4  A 400 (-4.6A)
 1.31A 3nliA-1nrkA:
0.0
3nliB-1nrkA:
0.0		 3nliA-1nrkA:
21.63
3nliB-1nrkA:
21.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLI_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 1nrk YGFZ PROTEIN
(Escherichia
coli) 		4 / 6 PHE A 154
VAL A 200
ARG A 160
TRP A  27
 SO4  A 400 (-4.6A)
None
None
SO4  A 400 (-3.4A)
 1.30A 3nliA-1nrkA:
0.0
3nliB-1nrkA:
0.0		 3nliA-1nrkA:
21.63
3nliB-1nrkA:
21.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLP_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1nrk YGFZ PROTEIN
(Escherichia
coli) 		4 / 7 PHE A 154
VAL A 200
ARG A 160
TRP A  27
 SO4  A 400 (-4.6A)
None
None
SO4  A 400 (-3.4A)
 1.32A 3nlpA-1nrkA:
0.0
3nlpB-1nrkA:
0.0		 3nlpA-1nrkA:
20.92
3nlpB-1nrkA:
20.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLQ_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1nrk YGFZ PROTEIN
(Escherichia
coli) 		4 / 7 PHE A 154
VAL A 200
ARG A 160
TRP A  27
 SO4  A 400 (-4.6A)
None
None
SO4  A 400 (-3.4A)
 1.27A 3nlqA-1nrkA:
0.0
3nlqB-1nrkA:
0.0		 3nlqA-1nrkA:
20.92
3nlqB-1nrkA:
20.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PNH_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 1nrk YGFZ PROTEIN
(Escherichia
coli) 		4 / 6 VAL A 200
ARG A 160
TRP A  27
PHE A 154
 None
None
SO4  A 400 (-3.4A)
SO4  A 400 (-4.6A)
 1.30A 3pnhA-1nrkA:
0.0
3pnhB-1nrkA:
0.0		 3pnhA-1nrkA:
22.30
3pnhB-1nrkA:
22.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PNH_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 1nrk YGFZ PROTEIN
(Escherichia
coli) 		4 / 6 PHE A 154
VAL A 200
ARG A 160
TRP A  27
 SO4  A 400 (-4.6A)
None
None
SO4  A 400 (-3.4A)
 1.31A 3pnhA-1nrkA:
0.0
3pnhB-1nrkA:
0.0		 3pnhA-1nrkA:
22.30
3pnhB-1nrkA:
22.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QXV_D_MTXD2000_2
(ANTI-METHOTREXATE
CDR1-4 GRAFT VHH)		 1nrk YGFZ PROTEIN
(Escherichia
coli) 		3 / 3 LEU A 162
ARG A  91
ASN A  72
 SO4  A 400 (-4.3A)
None
None
 0.76A 3qxvD-1nrkA:
undetectable		 3qxvD-1nrkA:
16.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ROX_A_TEPA266_1
(APOLIPOPROTEIN
A-I-BINDING PROTEIN)		 1nrk YGFZ PROTEIN
(Escherichia
coli) 		4 / 8 ALA A 247
VAL A 295
LEU A 280
LEU A 216
 None
 0.78A 3roxA-1nrkA:
undetectable		 3roxA-1nrkA:
22.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RQO_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 1nrk YGFZ PROTEIN
(Escherichia
coli) 		4 / 6 VAL A 200
ARG A 160
TRP A  27
PHE A 154
 None
None
SO4  A 400 (-3.4A)
SO4  A 400 (-4.6A)
 1.29A 3rqoA-1nrkA:
0.0
3rqoB-1nrkA:
0.0		 3rqoA-1nrkA:
21.24
3rqoB-1nrkA:
21.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RQO_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 1nrk YGFZ PROTEIN
(Escherichia
coli) 		4 / 6 PHE A 154
VAL A 200
ARG A 160
TRP A  27
 SO4  A 400 (-4.6A)
None
None
SO4  A 400 (-3.4A)
 1.29A 3rqoA-1nrkA:
0.0
3rqoB-1nrkA:
0.0		 3rqoA-1nrkA:
21.24
3rqoB-1nrkA:
21.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RQP_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 1nrk YGFZ PROTEIN
(Escherichia
coli) 		4 / 6 VAL A 200
ARG A 160
TRP A  27
PHE A 154
 None
None
SO4  A 400 (-3.4A)
SO4  A 400 (-4.6A)
 1.31A 3rqpA-1nrkA:
0.0
3rqpB-1nrkA:
0.0		 3rqpA-1nrkA:
21.24
3rqpB-1nrkA:
21.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RQP_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 1nrk YGFZ PROTEIN
(Escherichia
coli) 		4 / 5 PHE A 154
VAL A 200
ARG A 160
TRP A  27
 SO4  A 400 (-4.6A)
None
None
SO4  A 400 (-3.4A)
 1.31A 3rqpA-1nrkA:
0.0
3rqpB-1nrkA:
0.0		 3rqpA-1nrkA:
21.24
3rqpB-1nrkA:
21.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SNF_A_ACTA110_0
(PROTEIN P-30)		 1nrk YGFZ PROTEIN
(Escherichia
coli) 		4 / 5 ILE A 163
THR A 149
THR A 150
PHE A 133
 None
 1.13A 3snfA-1nrkA:
undetectable		 3snfA-1nrkA:
18.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C3A_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 1nrk YGFZ PROTEIN
(Escherichia
coli) 		4 / 6 PHE A 154
VAL A 200
ARG A 160
TRP A  27
 SO4  A 400 (-4.6A)
None
None
SO4  A 400 (-3.4A)
 1.33A 4c3aA-1nrkA:
0.0
4c3aB-1nrkA:
0.0		 4c3aA-1nrkA:
21.24
4c3aB-1nrkA:
21.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CFT_B_H4BB600_1
(ENDOTHELIAL NITRIC
OXIDE SYNTHASE)		 1nrk YGFZ PROTEIN
(Escherichia
coli) 		4 / 6 PHE A 154
VAL A 200
ARG A 160
TRP A  27
 SO4  A 400 (-4.6A)
None
None
SO4  A 400 (-3.4A)
 1.34A 4cftA-1nrkA:
0.0
4cftB-1nrkA:
0.0		 4cftA-1nrkA:
21.24
4cftB-1nrkA:
21.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CTY_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 1nrk YGFZ PROTEIN
(Escherichia
coli) 		4 / 6 PHE A 154
VAL A 200
ARG A 160
TRP A  27
 SO4  A 400 (-4.6A)
None
None
SO4  A 400 (-3.4A)
 1.28A 4ctyA-1nrkA:
0.0
4ctyB-1nrkA:
0.0		 4ctyA-1nrkA:
21.24
4ctyB-1nrkA:
21.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CTZ_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 1nrk YGFZ PROTEIN
(Escherichia
coli) 		4 / 6 PHE A 154
VAL A 200
ARG A 160
TRP A  27
 SO4  A 400 (-4.6A)
None
None
SO4  A 400 (-3.4A)
 1.35A 4ctzA-1nrkA:
0.0
4ctzB-1nrkA:
0.0		 4ctzA-1nrkA:
21.24
4ctzB-1nrkA:
21.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CU0_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 1nrk YGFZ PROTEIN
(Escherichia
coli) 		4 / 6 VAL A 200
ARG A 160
TRP A  27
PHE A 154
 None
None
SO4  A 400 (-3.4A)
SO4  A 400 (-4.6A)
 1.33A 4cu0A-1nrkA:
0.0
4cu0B-1nrkA:
0.0		 4cu0A-1nrkA:
21.24
4cu0B-1nrkA:
21.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CU0_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 1nrk YGFZ PROTEIN
(Escherichia
coli) 		4 / 6 PHE A 154
VAL A 200
ARG A 160
TRP A  27
 SO4  A 400 (-4.6A)
None
None
SO4  A 400 (-3.4A)
 1.30A 4cu0A-1nrkA:
0.0
4cu0B-1nrkA:
0.0		 4cu0A-1nrkA:
21.24
4cu0B-1nrkA:
21.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CWW_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 1nrk YGFZ PROTEIN
(Escherichia
coli) 		4 / 6 PHE A 154
VAL A 200
ARG A 160
TRP A  27
 SO4  A 400 (-4.6A)
None
None
SO4  A 400 (-3.4A)
 1.33A 4cwwA-1nrkA:
0.0
4cwwB-1nrkA:
0.0		 4cwwA-1nrkA:
21.24
4cwwB-1nrkA:
21.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CWX_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 1nrk YGFZ PROTEIN
(Escherichia
coli) 		4 / 7 PHE A 154
VAL A 200
ARG A 160
TRP A  27
 SO4  A 400 (-4.6A)
None
None
SO4  A 400 (-3.4A)
 1.34A 4cwxA-1nrkA:
0.0
4cwxB-1nrkA:
0.0		 4cwxA-1nrkA:
21.24
4cwxB-1nrkA:
21.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CX0_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 1nrk YGFZ PROTEIN
(Escherichia
coli) 		4 / 6 VAL A 200
ARG A 160
TRP A  27
PHE A 154
 None
None
SO4  A 400 (-3.4A)
SO4  A 400 (-4.6A)
 1.30A 4cx0A-1nrkA:
0.0
4cx0B-1nrkA:
0.0		 4cx0A-1nrkA:
21.24
4cx0B-1nrkA:
21.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CX0_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 1nrk YGFZ PROTEIN
(Escherichia
coli) 		4 / 6 PHE A 154
VAL A 200
ARG A 160
TRP A  27
 SO4  A 400 (-4.6A)
None
None
SO4  A 400 (-3.4A)
 1.32A 4cx0A-1nrkA:
0.0
4cx0B-1nrkA:
0.0		 4cx0A-1nrkA:
21.24
4cx0B-1nrkA:
21.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CX3_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1nrk YGFZ PROTEIN
(Escherichia
coli) 		4 / 7 VAL A 200
ARG A 160
TRP A  27
PHE A 154
 None
None
SO4  A 400 (-3.4A)
SO4  A 400 (-4.6A)
 1.28A 4cx3A-1nrkA:
0.0
4cx3B-1nrkA:
0.0		 4cx3A-1nrkA:
20.92
4cx3B-1nrkA:
20.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D1O_B_H4BB1481_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 1nrk YGFZ PROTEIN
(Escherichia
coli) 		4 / 6 PHE A 154
VAL A 200
ARG A 160
TRP A  27
 SO4  A 400 (-4.6A)
None
None
SO4  A 400 (-3.4A)
 1.33A 4d1oA-1nrkA:
0.0
4d1oB-1nrkA:
0.0		 4d1oA-1nrkA:
22.63
4d1oB-1nrkA:
22.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D1P_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 1nrk YGFZ PROTEIN
(Escherichia
coli) 		4 / 6 PHE A 154
VAL A 200
ARG A 160
TRP A  27
 SO4  A 400 (-4.6A)
None
None
SO4  A 400 (-3.4A)
 1.27A 4d1pA-1nrkA:
0.0
4d1pB-1nrkA:
0.0		 4d1pA-1nrkA:
22.63
4d1pB-1nrkA:
22.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D34_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 1nrk YGFZ PROTEIN
(Escherichia
coli) 		4 / 6 VAL A 200
ARG A 160
TRP A  27
PHE A 154
 None
None
SO4  A 400 (-3.4A)
SO4  A 400 (-4.6A)
 1.34A 4d34A-1nrkA:
0.0
4d34B-1nrkA:
0.0		 4d34A-1nrkA:
21.24
4d34B-1nrkA:
21.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D34_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 1nrk YGFZ PROTEIN
(Escherichia
coli) 		4 / 6 PHE A 154
VAL A 200
ARG A 160
TRP A  27
 SO4  A 400 (-4.6A)
None
None
SO4  A 400 (-3.4A)
 1.30A 4d34A-1nrkA:
0.0
4d34B-1nrkA:
0.0		 4d34A-1nrkA:
21.24
4d34B-1nrkA:
21.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D36_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 1nrk YGFZ PROTEIN
(Escherichia
coli) 		4 / 6 PHE A 154
VAL A 200
ARG A 160
TRP A  27
 SO4  A 400 (-4.6A)
None
None
SO4  A 400 (-3.4A)
 1.34A 4d36A-1nrkA:
0.0
4d36B-1nrkA:
0.0		 4d36A-1nrkA:
21.24
4d36B-1nrkA:
21.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D37_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 1nrk YGFZ PROTEIN
(Escherichia
coli) 		4 / 6 PHE A 154
VAL A 200
ARG A 160
TRP A  27
 SO4  A 400 (-4.6A)
None
None
SO4  A 400 (-3.4A)
 1.33A 4d37A-1nrkA:
0.0
4d37B-1nrkA:
0.0		 4d37A-1nrkA:
21.24
4d37B-1nrkA:
21.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D38_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 1nrk YGFZ PROTEIN
(Escherichia
coli) 		4 / 6 PHE A 154
VAL A 200
ARG A 160
TRP A  27
 SO4  A 400 (-4.6A)
None
None
SO4  A 400 (-3.4A)
 1.35A 4d38A-1nrkA:
0.0
4d38B-1nrkA:
0.0		 4d38A-1nrkA:
21.24
4d38B-1nrkA:
21.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D39_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 1nrk YGFZ PROTEIN
(Escherichia
coli) 		4 / 6 PHE A 154
VAL A 200
ARG A 160
TRP A  27
 SO4  A 400 (-4.6A)
None
None
SO4  A 400 (-3.4A)
 1.36A 4d39A-1nrkA:
0.0
4d39B-1nrkA:
0.0		 4d39A-1nrkA:
21.24
4d39B-1nrkA:
21.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D3A_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 1nrk YGFZ PROTEIN
(Escherichia
coli) 		4 / 6 PHE A 154
VAL A 200
ARG A 160
TRP A  27
 SO4  A 400 (-4.6A)
None
None
SO4  A 400 (-3.4A)
 1.34A 4d3aA-1nrkA:
0.0
4d3aB-1nrkA:
0.0		 4d3aA-1nrkA:
21.24
4d3aB-1nrkA:
21.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IMX_A_H4BA502_1
(SUBUNIT A)		 1nrk YGFZ PROTEIN
(Escherichia
coli) 		4 / 6 VAL A 200
ARG A 160
TRP A  27
PHE A 154
 None
None
SO4  A 400 (-3.4A)
SO4  A 400 (-4.6A)
 1.33A 4imxA-1nrkA:
0.0
4imxB-1nrkA:
0.0		 4imxA-1nrkA:
21.46
4imxB-1nrkA:
21.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IMX_B_H4BB502_1
(SUBUNIT A)		 1nrk YGFZ PROTEIN
(Escherichia
coli) 		4 / 6 PHE A 154
VAL A 200
ARG A 160
TRP A  27
 SO4  A 400 (-4.6A)
None
None
SO4  A 400 (-3.4A)
 1.31A 4imxA-1nrkA:
0.0
4imxB-1nrkA:
0.0		 4imxA-1nrkA:
21.46
4imxB-1nrkA:
21.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JSK_B_H4BB502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 1nrk YGFZ PROTEIN
(Escherichia
coli) 		4 / 6 PHE A 154
VAL A 200
ARG A 160
TRP A  27
 SO4  A 400 (-4.6A)
None
None
SO4  A 400 (-3.4A)
 1.31A 4jskA-1nrkA:
0.0
4jskB-1nrkA:
0.0		 4jskA-1nrkA:
21.24
4jskB-1nrkA:
21.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JSL_A_H4BA502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 1nrk YGFZ PROTEIN
(Escherichia
coli) 		4 / 6 VAL A 200
ARG A 160
TRP A  27
PHE A 154
 None
None
SO4  A 400 (-3.4A)
SO4  A 400 (-4.6A)
 1.31A 4jslA-1nrkA:
0.0
4jslB-1nrkA:
0.0		 4jslA-1nrkA:
21.24
4jslB-1nrkA:
21.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JSL_B_H4BB502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 1nrk YGFZ PROTEIN
(Escherichia
coli) 		4 / 6 PHE A 154
VAL A 200
ARG A 160
TRP A  27
 SO4  A 400 (-4.6A)
None
None
SO4  A 400 (-3.4A)
 1.31A 4jslA-1nrkA:
0.0
4jslB-1nrkA:
0.0		 4jslA-1nrkA:
21.24
4jslB-1nrkA:
21.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JSM_B_H4BB502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 1nrk YGFZ PROTEIN
(Escherichia
coli) 		4 / 6 PHE A 154
VAL A 200
ARG A 160
TRP A  27
 SO4  A 400 (-4.6A)
None
None
SO4  A 400 (-3.4A)
 1.34A 4jsmA-1nrkA:
0.0
4jsmB-1nrkA:
0.0		 4jsmA-1nrkA:
21.24
4jsmB-1nrkA:
21.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K5J_B_H4BB502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 1nrk YGFZ PROTEIN
(Escherichia
coli) 		4 / 7 PHE A 154
VAL A 200
ARG A 160
TRP A  27
 SO4  A 400 (-4.6A)
None
None
SO4  A 400 (-3.4A)
 1.34A 4k5jA-1nrkA:
undetectable
4k5jB-1nrkA:
undetectable		 4k5jA-1nrkA:
21.24
4k5jB-1nrkA:
21.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K5K_B_H4BB502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 1nrk YGFZ PROTEIN
(Escherichia
coli) 		4 / 6 PHE A 154
VAL A 200
ARG A 160
TRP A  27
 SO4  A 400 (-4.6A)
None
None
SO4  A 400 (-3.4A)
 1.35A 4k5kA-1nrkA:
0.0
4k5kB-1nrkA:
0.0		 4k5kA-1nrkA:
21.24
4k5kB-1nrkA:
21.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KCP_B_H4BB502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 1nrk YGFZ PROTEIN
(Escherichia
coli) 		4 / 6 PHE A 154
VAL A 200
ARG A 160
TRP A  27
 SO4  A 400 (-4.6A)
None
None
SO4  A 400 (-3.4A)
 1.30A 4kcpA-1nrkA:
0.0
4kcpB-1nrkA:
0.0		 4kcpA-1nrkA:
21.24
4kcpB-1nrkA:
21.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KCR_B_H4BB502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 1nrk YGFZ PROTEIN
(Escherichia
coli) 		4 / 6 PHE A 154
VAL A 200
ARG A 160
TRP A  27
 SO4  A 400 (-4.6A)
None
None
SO4  A 400 (-3.4A)
 1.34A 4kcrA-1nrkA:
0.0
4kcrB-1nrkA:
0.0		 4kcrA-1nrkA:
21.24
4kcrB-1nrkA:
21.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KCS_B_H4BB502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 1nrk YGFZ PROTEIN
(Escherichia
coli) 		4 / 6 PHE A 154
VAL A 200
ARG A 160
TRP A  27
 SO4  A 400 (-4.6A)
None
None
SO4  A 400 (-3.4A)
 1.36A 4kcsA-1nrkA:
0.0
4kcsB-1nrkA:
0.0		 4kcsA-1nrkA:
21.24
4kcsB-1nrkA:
21.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LUW_A_H4BA502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 1nrk YGFZ PROTEIN
(Escherichia
coli) 		4 / 6 VAL A 200
ARG A 160
TRP A  27
PHE A 154
 None
None
SO4  A 400 (-3.4A)
SO4  A 400 (-4.6A)
 1.36A 4luwA-1nrkA:
0.0
4luwB-1nrkA:
0.0		 4luwA-1nrkA:
21.46
4luwB-1nrkA:
21.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LUW_B_H4BB502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 1nrk YGFZ PROTEIN
(Escherichia
coli) 		4 / 6 PHE A 154
VAL A 200
ARG A 160
TRP A  27
 SO4  A 400 (-4.6A)
None
None
SO4  A 400 (-3.4A)
 1.31A 4luwA-1nrkA:
0.0
4luwB-1nrkA:
0.0		 4luwA-1nrkA:
21.46
4luwB-1nrkA:
21.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M11_A_MXMA606_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 1nrk YGFZ PROTEIN
(Escherichia
coli) 		5 / 12 ILE A 194
LEU A 258
LEU A 190
ALA A 261
LEU A 280
 None
 1.12A 4m11A-1nrkA:
0.0		 4m11A-1nrkA:
19.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M11_C_MXMC606_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 1nrk YGFZ PROTEIN
(Escherichia
coli) 		5 / 12 ILE A 194
LEU A 258
LEU A 190
ALA A 261
LEU A 280
 None
 1.15A 4m11C-1nrkA:
0.0		 4m11C-1nrkA:
19.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M11_D_MXMD606_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 1nrk YGFZ PROTEIN
(Escherichia
coli) 		5 / 12 ILE A 194
LEU A 258
LEU A 190
ALA A 261
LEU A 280
 None
 1.13A 4m11D-1nrkA:
0.0		 4m11D-1nrkA:
19.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NSB_A_AINA402_1
(CHITINASE-3-LIKE
PROTEIN 1)		 1nrk YGFZ PROTEIN
(Escherichia
coli) 		4 / 7 THR A  31
ARG A 115
TRP A  84
LEU A  29
 None
 1.49A 4nsbA-1nrkA:
undetectable		 4nsbA-1nrkA:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UH7_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 1nrk YGFZ PROTEIN
(Escherichia
coli) 		4 / 6 VAL A 200
ARG A 160
TRP A  27
PHE A 154
 None
None
SO4  A 400 (-3.4A)
SO4  A 400 (-4.6A)
 1.37A 4uh7A-1nrkA:
0.0
4uh7B-1nrkA:
0.0		 4uh7A-1nrkA:
21.24
4uh7B-1nrkA:
21.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UH7_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 1nrk YGFZ PROTEIN
(Escherichia
coli) 		4 / 6 PHE A 154
VAL A 200
ARG A 160
TRP A  27
 SO4  A 400 (-4.6A)
None
None
SO4  A 400 (-3.4A)
 1.35A 4uh7A-1nrkA:
0.0
4uh7B-1nrkA:
0.0		 4uh7A-1nrkA:
21.24
4uh7B-1nrkA:
21.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UH8_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 1nrk YGFZ PROTEIN
(Escherichia
coli) 		4 / 6 PHE A 154
VAL A 200
ARG A 160
TRP A  27
 SO4  A 400 (-4.6A)
None
None
SO4  A 400 (-3.4A)
 1.36A 4uh8A-1nrkA:
0.0
4uh8B-1nrkA:
0.0		 4uh8A-1nrkA:
21.24
4uh8B-1nrkA:
21.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UHA_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 1nrk YGFZ PROTEIN
(Escherichia
coli) 		4 / 6 PHE A 154
VAL A 200
ARG A 160
TRP A  27
 SO4  A 400 (-4.6A)
None
None
SO4  A 400 (-3.4A)
 1.32A 4uhaA-1nrkA:
0.0
4uhaB-1nrkA:
0.0		 4uhaA-1nrkA:
21.24
4uhaB-1nrkA:
21.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UPQ_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 1nrk YGFZ PROTEIN
(Escherichia
coli) 		4 / 6 PHE A 154
VAL A 200
ARG A 160
TRP A  27
 SO4  A 400 (-4.6A)
None
None
SO4  A 400 (-3.4A)
 1.34A 4upqA-1nrkA:
0.0
4upqB-1nrkA:
0.0		 4upqA-1nrkA:
21.24
4upqB-1nrkA:
21.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UPR_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 1nrk YGFZ PROTEIN
(Escherichia
coli) 		4 / 6 VAL A 200
ARG A 160
TRP A  27
PHE A 154
 None
None
SO4  A 400 (-3.4A)
SO4  A 400 (-4.6A)
 1.34A 4uprA-1nrkA:
0.0
4uprB-1nrkA:
0.0		 4uprA-1nrkA:
21.24
4uprB-1nrkA:
21.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UPR_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 1nrk YGFZ PROTEIN
(Escherichia
coli) 		4 / 6 PHE A 154
VAL A 200
ARG A 160
TRP A  27
 SO4  A 400 (-4.6A)
None
None
SO4  A 400 (-3.4A)
 1.32A 4uprA-1nrkA:
0.0
4uprB-1nrkA:
0.0		 4uprA-1nrkA:
21.24
4uprB-1nrkA:
21.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UPS_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 1nrk YGFZ PROTEIN
(Escherichia
coli) 		4 / 6 VAL A 200
ARG A 160
TRP A  27
PHE A 154
 None
None
SO4  A 400 (-3.4A)
SO4  A 400 (-4.6A)
 1.36A 4upsA-1nrkA:
0.0
4upsB-1nrkA:
0.0		 4upsA-1nrkA:
21.24
4upsB-1nrkA:
21.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UPS_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 1nrk YGFZ PROTEIN
(Escherichia
coli) 		4 / 6 PHE A 154
VAL A 200
ARG A 160
TRP A  27
 SO4  A 400 (-4.6A)
None
None
SO4  A 400 (-3.4A)
 1.34A 4upsA-1nrkA:
0.0
4upsB-1nrkA:
0.0		 4upsA-1nrkA:
21.24
4upsB-1nrkA:
21.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UPT_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 1nrk YGFZ PROTEIN
(Escherichia
coli) 		4 / 6 VAL A 200
ARG A 160
TRP A  27
PHE A 154
 None
None
SO4  A 400 (-3.4A)
SO4  A 400 (-4.6A)
 1.32A 4uptA-1nrkA:
0.0
4uptB-1nrkA:
0.0		 4uptA-1nrkA:
21.24
4uptB-1nrkA:
21.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UPT_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 1nrk YGFZ PROTEIN
(Escherichia
coli) 		4 / 6 PHE A 154
VAL A 200
ARG A 160
TRP A  27
 SO4  A 400 (-4.6A)
None
None
SO4  A 400 (-3.4A)
 1.28A 4uptA-1nrkA:
0.0
4uptB-1nrkA:
0.0		 4uptA-1nrkA:
21.24
4uptB-1nrkA:
21.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ADD_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1nrk YGFZ PROTEIN
(Escherichia
coli) 		4 / 6 VAL A 200
ARG A 160
TRP A  27
PHE A 154
 None
None
SO4  A 400 (-3.4A)
SO4  A 400 (-4.6A)
 1.31A 5addA-1nrkA:
0.0
5addB-1nrkA:
0.0		 5addA-1nrkA:
20.92
5addB-1nrkA:
20.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ADJ_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 1nrk YGFZ PROTEIN
(Escherichia
coli) 		4 / 6 PHE A 154
VAL A 200
ARG A 160
TRP A  27
 SO4  A 400 (-4.6A)
None
None
SO4  A 400 (-3.4A)
 1.36A 5adjA-1nrkA:
0.0
5adjB-1nrkA:
0.0		 5adjA-1nrkA:
21.24
5adjB-1nrkA:
21.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ADK_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 1nrk YGFZ PROTEIN
(Escherichia
coli) 		4 / 6 PHE A 154
VAL A 200
ARG A 160
TRP A  27
 SO4  A 400 (-4.6A)
None
None
SO4  A 400 (-3.4A)
 1.34A 5adkA-1nrkA:
0.0
5adkB-1nrkA:
0.0		 5adkA-1nrkA:
21.24
5adkB-1nrkA:
21.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ADM_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 1nrk YGFZ PROTEIN
(Escherichia
coli) 		4 / 6 VAL A 200
ARG A 160
TRP A  27
PHE A 154
 None
None
SO4  A 400 (-3.4A)
SO4  A 400 (-4.6A)
 1.36A 5admA-1nrkA:
0.0
5admB-1nrkA:
0.0		 5admA-1nrkA:
21.24
5admB-1nrkA:
21.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ADM_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 1nrk YGFZ PROTEIN
(Escherichia
coli) 		4 / 6 PHE A 154
VAL A 200
ARG A 160
TRP A  27
 SO4  A 400 (-4.6A)
None
None
SO4  A 400 (-3.4A)
 1.33A 5admA-1nrkA:
0.0
5admB-1nrkA:
0.0		 5admA-1nrkA:
21.24
5admB-1nrkA:
21.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FJ2_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 1nrk YGFZ PROTEIN
(Escherichia
coli) 		4 / 6 PHE A 154
VAL A 200
ARG A 160
TRP A  27
 SO4  A 400 (-4.6A)
None
None
SO4  A 400 (-3.4A)
 1.35A 5fj2A-1nrkA:
0.0
5fj2B-1nrkA:
0.0		 5fj2A-1nrkA:
21.24
5fj2B-1nrkA:
21.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FJ3_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 1nrk YGFZ PROTEIN
(Escherichia
coli) 		4 / 7 PHE A 154
VAL A 200
ARG A 160
TRP A  27
 SO4  A 400 (-4.6A)
None
None
SO4  A 400 (-3.4A)
 1.30A 5fj3A-1nrkA:
undetectable
5fj3B-1nrkA:
undetectable		 5fj3A-1nrkA:
21.24
5fj3B-1nrkA:
21.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FVZ_A_H4BA600_1
(ENDOTHELIAL NITRIC
OXIDE SYNTHASE)		 1nrk YGFZ PROTEIN
(Escherichia
coli) 		4 / 6 VAL A 200
ARG A 160
TRP A  27
PHE A 154
 None
None
SO4  A 400 (-3.4A)
SO4  A 400 (-4.6A)
 1.34A 5fvzA-1nrkA:
0.0
5fvzB-1nrkA:
0.0		 5fvzA-1nrkA:
21.24
5fvzB-1nrkA:
21.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FVZ_B_H4BB600_1
(ENDOTHELIAL NITRIC
OXIDE SYNTHASE)		 1nrk YGFZ PROTEIN
(Escherichia
coli) 		4 / 6 PHE A 154
VAL A 200
ARG A 160
TRP A  27
 SO4  A 400 (-4.6A)
None
None
SO4  A 400 (-3.4A)
 1.32A 5fvzA-1nrkA:
0.0
5fvzB-1nrkA:
0.0		 5fvzA-1nrkA:
21.24
5fvzB-1nrkA:
21.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MFX_A_ACTA701_0
(GENOME POLYPROTEIN)		 1nrk YGFZ PROTEIN
(Escherichia
coli) 		4 / 5 ARG A  91
THR A  31
ALA A 110
ASP A 112
 None
 1.08A 5mfxA-1nrkA:
undetectable		 5mfxA-1nrkA:
21.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UO8_B_H4BB502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 1nrk YGFZ PROTEIN
(Escherichia
coli) 		4 / 6 PHE A 154
VAL A 200
ARG A 160
TRP A  27
 SO4  A 400 (-4.6A)
None
None
SO4  A 400 (-3.4A)
 1.32A 5uo8A-1nrkA:
0.0
5uo8B-1nrkA:
0.0		 5uo8A-1nrkA:
22.63
5uo8B-1nrkA:
22.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UO8_C_H4BC502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 1nrk YGFZ PROTEIN
(Escherichia
coli) 		4 / 6 VAL A 200
ARG A 160
TRP A  27
PHE A 154
 None
None
SO4  A 400 (-3.4A)
SO4  A 400 (-4.6A)
 1.33A 5uo8C-1nrkA:
0.0
5uo8D-1nrkA:
0.0		 5uo8C-1nrkA:
22.63
5uo8D-1nrkA:
22.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UO8_D_H4BD502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 1nrk YGFZ PROTEIN
(Escherichia
coli) 		4 / 6 PHE A 154
VAL A 200
ARG A 160
TRP A  27
 SO4  A 400 (-4.6A)
None
None
SO4  A 400 (-3.4A)
 1.35A 5uo8C-1nrkA:
0.0
5uo8D-1nrkA:
0.0		 5uo8C-1nrkA:
22.63
5uo8D-1nrkA:
22.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UO9_A_H4BA502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 1nrk YGFZ PROTEIN
(Escherichia
coli) 		4 / 6 VAL A 200
ARG A 160
TRP A  27
PHE A 154
 None
None
SO4  A 400 (-3.4A)
SO4  A 400 (-4.6A)
 1.35A 5uo9A-1nrkA:
0.0
5uo9B-1nrkA:
0.0		 5uo9A-1nrkA:
22.63
5uo9B-1nrkA:
22.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UOC_A_H4BA502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 1nrk YGFZ PROTEIN
(Escherichia
coli) 		4 / 5 VAL A 200
ARG A 160
TRP A  27
PHE A 154
 None
None
SO4  A 400 (-3.4A)
SO4  A 400 (-4.6A)
 1.28A 5uocA-1nrkA:
0.0
5uocB-1nrkA:
0.0		 5uocA-1nrkA:
22.63
5uocB-1nrkA:
22.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VV7_B_H4BB502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 1nrk YGFZ PROTEIN
(Escherichia
coli) 		4 / 7 PHE A 154
VAL A 200
ARG A 160
TRP A  27
 SO4  A 400 (-4.6A)
None
None
SO4  A 400 (-3.4A)
 1.32A 5vv7A-1nrkA:
undetectable
5vv7B-1nrkA:
undetectable		 5vv7A-1nrkA:
21.24
5vv7B-1nrkA:
21.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VVC_A_H4BA502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 1nrk YGFZ PROTEIN
(Escherichia
coli) 		4 / 6 VAL A 200
ARG A 160
TRP A  27
PHE A 154
 None
None
SO4  A 400 (-3.4A)
SO4  A 400 (-4.6A)
 1.31A 5vvcA-1nrkA:
0.0
5vvcB-1nrkA:
0.0		 5vvcA-1nrkA:
22.63
5vvcB-1nrkA:
22.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VVC_C_H4BC502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 1nrk YGFZ PROTEIN
(Escherichia
coli) 		4 / 6 VAL A 200
ARG A 160
TRP A  27
PHE A 154
 None
None
SO4  A 400 (-3.4A)
SO4  A 400 (-4.6A)
 1.34A 5vvcC-1nrkA:
0.0
5vvcD-1nrkA:
0.0		 5vvcC-1nrkA:
22.63
5vvcD-1nrkA:
22.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VVC_D_H4BD502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 1nrk YGFZ PROTEIN
(Escherichia
coli) 		4 / 6 PHE A 154
VAL A 200
ARG A 160
TRP A  27
 SO4  A 400 (-4.6A)
None
None
SO4  A 400 (-3.4A)
 1.29A 5vvcC-1nrkA:
0.0
5vvcD-1nrkA:
0.0		 5vvcC-1nrkA:
22.63
5vvcD-1nrkA:
22.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VVD_B_H4BB502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 1nrk YGFZ PROTEIN
(Escherichia
coli) 		4 / 7 PHE A 154
VAL A 200
ARG A 160
TRP A  27
 SO4  A 400 (-4.6A)
None
None
SO4  A 400 (-3.4A)
 1.29A 5vvdA-1nrkA:
0.0
5vvdB-1nrkA:
0.0		 5vvdA-1nrkA:
22.63
5vvdB-1nrkA:
22.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VVD_C_H4BC502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 1nrk YGFZ PROTEIN
(Escherichia
coli) 		4 / 6 VAL A 200
ARG A 160
TRP A  27
PHE A 154
 None
None
SO4  A 400 (-3.4A)
SO4  A 400 (-4.6A)
 1.38A 5vvdC-1nrkA:
0.0
5vvdD-1nrkA:
0.0		 5vvdC-1nrkA:
22.63
5vvdD-1nrkA:
22.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VVG_B_H4BB502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 1nrk YGFZ PROTEIN
(Escherichia
coli) 		4 / 6 PHE A 154
VAL A 200
ARG A 160
TRP A  27
 SO4  A 400 (-4.6A)
None
None
SO4  A 400 (-3.4A)
 1.32A 5vvgA-1nrkA:
0.0
5vvgB-1nrkA:
0.0		 5vvgA-1nrkA:
21.24
5vvgB-1nrkA:
21.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VVN_B_H4BB502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 1nrk YGFZ PROTEIN
(Escherichia
coli) 		4 / 7 PHE A 154
VAL A 200
ARG A 160
TRP A  27
 SO4  A 400 (-4.6A)
None
None
SO4  A 400 (-3.4A)
 1.32A 5vvnA-1nrkA:
undetectable
5vvnB-1nrkA:
undetectable		 5vvnA-1nrkA:
21.24
5vvnB-1nrkA:
21.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X2T_I_PEMI202_1
(HEMOGLOBIN SUBUNIT
ALPHA
HEMOGLOBIN SUBUNIT
BETA)		 1nrk YGFZ PROTEIN
(Escherichia
coli) 		4 / 8 ALA A  65
THR A 230
ALA A 102
TRP A  84
 None
 0.96A 5x2tI-1nrkA:
undetectable
5x2tJ-1nrkA:
undetectable
5x2tK-1nrkA:
undetectable
5x2tL-1nrkA:
undetectable		 5x2tI-1nrkA:
16.77
5x2tJ-1nrkA:
18.04
5x2tK-1nrkA:
16.77
5x2tL-1nrkA:
18.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XIO_A_HFGA801_0
(PROLINE-TRNA
SYNTHETASE CLASS II
AARS (YBAK RNA
BINDING DOMAIN PLUS
TRNA SYNTHETASE))		 1nrk YGFZ PROTEIN
(Escherichia
coli) 		5 / 12 PHE A 133
VAL A 144
PRO A 137
GLU A 159
GLY A 122
 None
 1.44A 5xioA-1nrkA:
undetectable		 5xioA-1nrkA:
20.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AV6_B_H4BB501_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 1nrk YGFZ PROTEIN
(Escherichia
coli) 		4 / 7 VAL A 200
ARG A 160
TRP A  27
PHE A 154
 None
None
SO4  A 400 (-3.4A)
SO4  A 400 (-4.6A)
 1.26A 6av6A-1nrkA:
undetectable
6av6B-1nrkA:
undetectable		 6av6A-1nrkA:
12.79
6av6B-1nrkA:
12.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AV6_C_H4BC502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 1nrk YGFZ PROTEIN
(Escherichia
coli) 		4 / 6 VAL A 200
ARG A 160
TRP A  27
PHE A 154
 None
None
SO4  A 400 (-3.4A)
SO4  A 400 (-4.6A)
 1.28A 6av6C-1nrkA:
0.0
6av6D-1nrkA:
0.0		 6av6C-1nrkA:
12.79
6av6D-1nrkA:
12.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AV7_A_H4BA502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 1nrk YGFZ PROTEIN
(Escherichia
coli) 		4 / 7 VAL A 200
ARG A 160
TRP A  27
PHE A 154
 None
None
SO4  A 400 (-3.4A)
SO4  A 400 (-4.6A)
 1.34A 6av7A-1nrkA:
undetectable
6av7B-1nrkA:
undetectable		 6av7A-1nrkA:
12.79
6av7B-1nrkA:
12.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AV7_B_H4BB502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 1nrk YGFZ PROTEIN
(Escherichia
coli) 		4 / 6 PHE A 154
VAL A 200
ARG A 160
TRP A  27
 SO4  A 400 (-4.6A)
None
None
SO4  A 400 (-3.4A)
 1.34A 6av7A-1nrkA:
0.0
6av7B-1nrkA:
0.0		 6av7A-1nrkA:
12.79
6av7B-1nrkA:
12.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AV7_C_H4BC502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 1nrk YGFZ PROTEIN
(Escherichia
coli) 		4 / 6 VAL A 200
ARG A 160
TRP A  27
PHE A 154
 None
None
SO4  A 400 (-3.4A)
SO4  A 400 (-4.6A)
 1.38A 6av7C-1nrkA:
0.0
6av7D-1nrkA:
0.0		 6av7C-1nrkA:
12.79
6av7D-1nrkA:
12.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CIE_A_H4BA502_0
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 1nrk YGFZ PROTEIN
(Escherichia
coli) 		4 / 6 VAL A 200
ARG A 160
TRP A  27
PHE A 154
 None
None
SO4  A 400 (-3.4A)
SO4  A 400 (-4.6A)
 1.34A 6cieA-1nrkA:
0.0
6cieB-1nrkA:
0.0		 6cieA-1nrkA:
12.79
6cieB-1nrkA:
12.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CIE_C_H4BC502_0
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 1nrk YGFZ PROTEIN
(Escherichia
coli) 		4 / 6 VAL A 200
ARG A 160
TRP A  27
PHE A 154
 None
None
SO4  A 400 (-3.4A)
SO4  A 400 (-4.6A)
 1.38A 6cieC-1nrkA:
0.0
6cieD-1nrkA:
0.0		 6cieC-1nrkA:
12.79
6cieD-1nrkA:
12.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6ESM_A_PZEA307_1
(MATRIX
METALLOPROTEINASE-9,
MATRIX
METALLOPROTEINASE-9)		 1nrk YGFZ PROTEIN
(Escherichia
coli) 		3 / 3 TYR A 322
HIS A 156
PHE A 198
 None
 1.01A 6esmA-1nrkA:
undetectable		 6esmA-1nrkA:
13.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
8NSE_B_H4BB601_1
(PROTEIN (NITRIC
OXIDE SYNTHASE))		 1nrk YGFZ PROTEIN
(Escherichia
coli) 		4 / 6 PHE A 154
VAL A 200
ARG A 160
TRP A  27
 SO4  A 400 (-4.6A)
None
None
SO4  A 400 (-3.4A)
 1.29A 8nseA-1nrkA:
0.0
8nseB-1nrkA:
0.0		 8nseA-1nrkA:
21.41
8nseB-1nrkA:
21.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
9NSE_A_H4BA600_1
(PROTEIN (NITRIC
OXIDE SYNTHASE))		 1nrk YGFZ PROTEIN
(Escherichia
coli) 		4 / 6 VAL A 200
ARG A 160
TRP A  27
PHE A 154
 None
None
SO4  A 400 (-3.4A)
SO4  A 400 (-4.6A)
 1.35A 9nseA-1nrkA:
0.0
9nseB-1nrkA:
0.0		 9nseA-1nrkA:
21.41
9nseB-1nrkA:
21.41