SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1nrv'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B1A_C_CHDC304_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 1nrv GROWTH FACTOR
RECEPTOR-BOUND
PROTEIN 10
(Homo
sapiens) 		4 / 7 GLN A 485
PHE A 484
LEU A 512
PHE A 506
 None
 0.97A 5b1aC-1nrvA:
undetectable
5b1aJ-1nrvA:
undetectable		 5b1aC-1nrvA:
16.86
5b1aJ-1nrvA:
22.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B1A_P_CHDP305_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 1nrv GROWTH FACTOR
RECEPTOR-BOUND
PROTEIN 10
(Homo
sapiens) 		4 / 7 GLN A 485
PHE A 484
LEU A 512
PHE A 506
 None
 0.92A 5b1aP-1nrvA:
undetectable
5b1aW-1nrvA:
undetectable		 5b1aP-1nrvA:
16.86
5b1aW-1nrvA:
22.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IY5_C_CHDC307_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 1nrv GROWTH FACTOR
RECEPTOR-BOUND
PROTEIN 10
(Homo
sapiens) 		4 / 7 GLN A 485
PHE A 484
LEU A 512
PHE A 506
 None
 0.96A 5iy5C-1nrvA:
undetectable
5iy5J-1nrvA:
undetectable		 5iy5C-1nrvA:
16.99
5iy5J-1nrvA:
21.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z84_P_CHDP305_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 1nrv GROWTH FACTOR
RECEPTOR-BOUND
PROTEIN 10
(Homo
sapiens) 		4 / 6 GLN A 485
PHE A 484
LEU A 512
PHE A 506
 None
 0.99A 5z84P-1nrvA:
undetectable
5z84W-1nrvA:
undetectable		 5z84P-1nrvA:
16.86
5z84W-1nrvA:
22.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z85_P_CHDP307_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 1nrv GROWTH FACTOR
RECEPTOR-BOUND
PROTEIN 10
(Homo
sapiens) 		4 / 6 GLN A 485
PHE A 484
LEU A 512
PHE A 506
 None
 0.99A 5z85P-1nrvA:
undetectable
5z85W-1nrvA:
undetectable		 5z85P-1nrvA:
16.86
5z85W-1nrvA:
22.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z86_C_CHDC306_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 1nrv GROWTH FACTOR
RECEPTOR-BOUND
PROTEIN 10
(Homo
sapiens) 		4 / 6 GLN A 485
PHE A 484
LEU A 512
PHE A 506
 None
 1.01A 5z86C-1nrvA:
undetectable
5z86J-1nrvA:
undetectable		 5z86C-1nrvA:
16.86
5z86J-1nrvA:
22.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z86_P_CHDP307_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 1nrv GROWTH FACTOR
RECEPTOR-BOUND
PROTEIN 10
(Homo
sapiens) 		4 / 6 GLN A 485
PHE A 484
LEU A 512
PHE A 506
 None
 0.99A 5z86P-1nrvA:
undetectable
5z86W-1nrvA:
undetectable		 5z86P-1nrvA:
16.86
5z86W-1nrvA:
22.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCO_P_CHDP305_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 1nrv GROWTH FACTOR
RECEPTOR-BOUND
PROTEIN 10
(Homo
sapiens) 		4 / 6 GLN A 485
PHE A 484
LEU A 512
PHE A 506
 None
 1.00A 5zcoP-1nrvA:
undetectable
5zcoW-1nrvA:
undetectable		 5zcoP-1nrvA:
16.86
5zcoW-1nrvA:
22.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCP_C_CHDC306_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 1nrv GROWTH FACTOR
RECEPTOR-BOUND
PROTEIN 10
(Homo
sapiens) 		4 / 6 GLN A 485
PHE A 484
LEU A 512
PHE A 506
 None
 1.01A 5zcpC-1nrvA:
undetectable
5zcpJ-1nrvA:
undetectable		 5zcpC-1nrvA:
16.86
5zcpJ-1nrvA:
22.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCP_P_CHDP306_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 1nrv GROWTH FACTOR
RECEPTOR-BOUND
PROTEIN 10
(Homo
sapiens) 		4 / 6 GLN A 485
PHE A 484
LEU A 512
PHE A 506
 None
 0.99A 5zcpP-1nrvA:
undetectable
5zcpW-1nrvA:
undetectable		 5zcpP-1nrvA:
16.86
5zcpW-1nrvA:
22.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NMP_C_CHDC307_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 1nrv GROWTH FACTOR
RECEPTOR-BOUND
PROTEIN 10
(Homo
sapiens) 		4 / 6 GLN A 485
PHE A 484
LEU A 512
PHE A 506
 None
 1.01A 6nmpC-1nrvA:
undetectable
6nmpJ-1nrvA:
undetectable		 6nmpC-1nrvA:
16.86
6nmpJ-1nrvA:
22.34