SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1nrw'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1AKD_A_CAMA420_0
(CYTOCHROME P450CAM)		 1nrw HYPOTHETICAL
PROTEIN, HALOACID
DEHALOGENASE-LIKE
HYDROLASE
(Bacillus
subtilis) 		5 / 11 GLY A 255
THR A 269
VAL A 235
ASP A 241
VAL A 252
 None
None
None
CA  A 903 ( 4.3A)
None
 1.20A 1akdA-1nrwA:
undetectable		 1akdA-1nrwA:
20.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PKV_A_RBFA100_1
(RIBOFLAVIN SYNTHASE
ALPHA CHAIN)		 1nrw HYPOTHETICAL
PROTEIN, HALOACID
DEHALOGENASE-LIKE
HYDROLASE
(Bacillus
subtilis) 		5 / 11 LEU A  12
THR A  11
THR A  59
ILE A  62
VAL A  61
 None
 0.92A 1pkvA-1nrwA:
undetectable
1pkvB-1nrwA:
undetectable		 1pkvA-1nrwA:
18.28
1pkvB-1nrwA:
18.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1U18_B_HSMB402_1
(NITROPHORIN 1)		 1nrw HYPOTHETICAL
PROTEIN, HALOACID
DEHALOGENASE-LIKE
HYDROLASE
(Bacillus
subtilis) 		4 / 5 ASP A 194
GLU A 193
LEU A 197
LEU A 195
 None
 1.22A 1u18B-1nrwA:
0.0		 1u18B-1nrwA:
23.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A1N_A_CAMA1422_0
(CYTOCHROME P450-CAM)		 1nrw HYPOTHETICAL
PROTEIN, HALOACID
DEHALOGENASE-LIKE
HYDROLASE
(Bacillus
subtilis) 		5 / 11 GLY A 255
THR A 269
VAL A 235
ASP A 241
VAL A 252
 None
None
None
CA  A 903 ( 4.3A)
None
 1.21A 2a1nA-1nrwA:
undetectable		 2a1nA-1nrwA:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NXE_A_SAMA302_1
(RIBOSOMAL PROTEIN
L11
METHYLTRANSFERASE)		 1nrw HYPOTHETICAL
PROTEIN, HALOACID
DEHALOGENASE-LIKE
HYDROLASE
(Bacillus
subtilis) 		3 / 3 THR A 111
ASP A  47
SER A  63
 None
 0.85A 2nxeA-1nrwA:
undetectable		 2nxeA-1nrwA:
25.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NXE_B_SAMB303_1
(RIBOSOMAL PROTEIN
L11
METHYLTRANSFERASE)		 1nrw HYPOTHETICAL
PROTEIN, HALOACID
DEHALOGENASE-LIKE
HYDROLASE
(Bacillus
subtilis) 		3 / 3 THR A 111
ASP A  47
SER A  63
 None
 0.82A 2nxeB-1nrwA:
3.2		 2nxeB-1nrwA:
25.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PYN_A_1UNA1001_3
(PROTEASE RETROPEPSIN)		 1nrw HYPOTHETICAL
PROTEIN, HALOACID
DEHALOGENASE-LIKE
HYDROLASE
(Bacillus
subtilis) 		3 / 3 ASP A 124
THR A 111
PRO A 112
 None
 0.61A 2pynB-1nrwA:
undetectable		 2pynB-1nrwA:
18.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q64_B_1UNB1001_4
(PROTEASE RETROPEPSIN)		 1nrw HYPOTHETICAL
PROTEIN, HALOACID
DEHALOGENASE-LIKE
HYDROLASE
(Bacillus
subtilis) 		3 / 3 ASP A 124
THR A 111
PRO A 112
 None
 0.62A 2q64B-1nrwA:
undetectable		 2q64B-1nrwA:
16.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QAK_A_1UNA1001_4
(PROTEASE RETROPEPSIN)		 1nrw HYPOTHETICAL
PROTEIN, HALOACID
DEHALOGENASE-LIKE
HYDROLASE
(Bacillus
subtilis) 		3 / 3 ASP A 124
THR A 111
PRO A 112
 None
 0.65A 2qakB-1nrwA:
undetectable		 2qakB-1nrwA:
16.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AVP_A_MV2A313_1
(PANTOTHENATE KINASE)		 1nrw HYPOTHETICAL
PROTEIN, HALOACID
DEHALOGENASE-LIKE
HYDROLASE
(Bacillus
subtilis) 		4 / 7 VAL A  48
ASP A   9
HIS A  17
ILE A  57
 None
PO4  A 900 ( 3.6A)
None
None
 1.04A 3avpA-1nrwA:
0.0		 3avpA-1nrwA:
20.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AY0_A_ADNA401_1
(UNCHARACTERIZED
PROTEIN MJ0883)		 1nrw HYPOTHETICAL
PROTEIN, HALOACID
DEHALOGENASE-LIKE
HYDROLASE
(Bacillus
subtilis) 		5 / 10 PHE A 169
ILE A 172
ASN A 171
ALA A  64
PHE A 161
 None
 1.41A 3ay0A-1nrwA:
undetectable		 3ay0A-1nrwA:
21.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FL9_F_TOPF200_1
(DIHYDROFOLATE
REDUCTASE (DHFR))		 1nrw HYPOTHETICAL
PROTEIN, HALOACID
DEHALOGENASE-LIKE
HYDROLASE
(Bacillus
subtilis) 		5 / 10 ASN A  14
LEU A  13
VAL A  39
LEU A  27
PHE A  52
 None
 1.19A 3fl9F-1nrwA:
undetectable		 3fl9F-1nrwA:
18.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HCN_A_CHDA3_0
(FERROCHELATASE,
MITOCHONDRIAL)		 1nrw HYPOTHETICAL
PROTEIN, HALOACID
DEHALOGENASE-LIKE
HYDROLASE
(Bacillus
subtilis) 		4 / 7 MET A 281
LEU A 285
GLY A 236
MET A 254
 None
 1.03A 3hcnA-1nrwA:
2.9		 3hcnA-1nrwA:
21.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HKU_A_TORA300_1
(CARBONIC ANHYDRASE 2)		 1nrw HYPOTHETICAL
PROTEIN, HALOACID
DEHALOGENASE-LIKE
HYDROLASE
(Bacillus
subtilis) 		5 / 12 ASN A 130
ALA A 129
ASN A 256
VAL A 235
LEU A  12
 None
 1.33A 3hkuA-1nrwA:
undetectable		 3hkuA-1nrwA:
22.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N2O_C_AG2C1002_1
(BIOSYNTHETIC
ARGININE
DECARBOXYLASE)		 1nrw HYPOTHETICAL
PROTEIN, HALOACID
DEHALOGENASE-LIKE
HYDROLASE
(Bacillus
subtilis) 		4 / 8 LYS A 214
LEU A 245
ASP A   7
ASP A 237
 PO4  A 900 (-2.8A)
None
PO4  A 900 ( 2.6A)
CA  A 903 (-2.9A)
 1.20A 3n2oC-1nrwA:
undetectable
3n2oD-1nrwA:
undetectable		 3n2oC-1nrwA:
19.67
3n2oD-1nrwA:
19.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TKG_C_ROCC901_3
(PROTEASE)		 1nrw HYPOTHETICAL
PROTEIN, HALOACID
DEHALOGENASE-LIKE
HYDROLASE
(Bacillus
subtilis) 		3 / 3 ASP A 124
THR A 111
PRO A 112
 None
 0.58A 3tkgD-1nrwA:
undetectable		 3tkgD-1nrwA:
16.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4BBO_C_ACTC1113_0
(BLR5658 PROTEIN)		 1nrw HYPOTHETICAL
PROTEIN, HALOACID
DEHALOGENASE-LIKE
HYDROLASE
(Bacillus
subtilis) 		4 / 4 ASN A 256
ALA A 257
GLY A 255
THR A 269
 None
 1.14A 4bboC-1nrwA:
undetectable		 4bboC-1nrwA:
19.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C9K_A_CAMA424_0
(CYTOCHROME P450)		 1nrw HYPOTHETICAL
PROTEIN, HALOACID
DEHALOGENASE-LIKE
HYDROLASE
(Bacillus
subtilis) 		5 / 9 THR A 269
LEU A 245
GLY A 236
THR A  11
VAL A 277
 None
 1.49A 4c9kA-1nrwA:
0.0		 4c9kA-1nrwA:
22.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N09_A_ADNA401_1
(ADENOSINE KINASE)		 1nrw HYPOTHETICAL
PROTEIN, HALOACID
DEHALOGENASE-LIKE
HYDROLASE
(Bacillus
subtilis) 		5 / 12 ASP A   7
LEU A   3
ASN A 240
ALA A   5
GLY A  42
 PO4  A 900 ( 2.6A)
None
PO4  A 900 (-3.6A)
None
PO4  A 900 (-3.8A)
 1.18A 4n09A-1nrwA:
4.0		 4n09A-1nrwA:
21.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Q5M_A_ROCA1101_3
(PROTEASE)		 1nrw HYPOTHETICAL
PROTEIN, HALOACID
DEHALOGENASE-LIKE
HYDROLASE
(Bacillus
subtilis) 		3 / 3 ASP A 237
ASP A   7
ASN A  65
 CA  A 903 (-2.9A)
PO4  A 900 ( 2.6A)
None
 0.82A 4q5mA-1nrwA:
undetectable		 4q5mA-1nrwA:
21.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4X1Y_D_LOCD502_2
(TUBULIN BETA CHAIN)		 1nrw HYPOTHETICAL
PROTEIN, HALOACID
DEHALOGENASE-LIKE
HYDROLASE
(Bacillus
subtilis) 		5 / 12 LEU A 285
MET A   1
ALA A 233
VAL A 235
ILE A   4
 None
 1.05A 4x1yD-1nrwA:
undetectable		 4x1yD-1nrwA:
20.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YB6_A_HISA302_0
(ATP
PHOSPHORIBOSYLTRANSF
ERASE)		 1nrw HYPOTHETICAL
PROTEIN, HALOACID
DEHALOGENASE-LIKE
HYDROLASE
(Bacillus
subtilis) 		5 / 10 VAL A 235
VAL A 252
MET A   1
LEU A 218
LEU A 285
 None
 0.97A 4yb6A-1nrwA:
undetectable
4yb6E-1nrwA:
undetectable		 4yb6A-1nrwA:
23.85
4yb6E-1nrwA:
23.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YB6_B_HISB302_0
(ATP
PHOSPHORIBOSYLTRANSF
ERASE)		 1nrw HYPOTHETICAL
PROTEIN, HALOACID
DEHALOGENASE-LIKE
HYDROLASE
(Bacillus
subtilis) 		5 / 10 VAL A 235
VAL A 252
MET A   1
LEU A 218
LEU A 285
 None
 0.97A 4yb6B-1nrwA:
undetectable
4yb6C-1nrwA:
undetectable		 4yb6B-1nrwA:
23.85
4yb6C-1nrwA:
23.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YB6_C_HISC302_0
(ATP
PHOSPHORIBOSYLTRANSF
ERASE)		 1nrw HYPOTHETICAL
PROTEIN, HALOACID
DEHALOGENASE-LIKE
HYDROLASE
(Bacillus
subtilis) 		5 / 10 VAL A 235
VAL A 252
MET A   1
LEU A 218
LEU A 285
 None
 0.99A 4yb6C-1nrwA:
undetectable
4yb6F-1nrwA:
undetectable		 4yb6C-1nrwA:
23.85
4yb6F-1nrwA:
23.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YB6_D_HISD302_0
(ATP
PHOSPHORIBOSYLTRANSF
ERASE)		 1nrw HYPOTHETICAL
PROTEIN, HALOACID
DEHALOGENASE-LIKE
HYDROLASE
(Bacillus
subtilis) 		5 / 10 MET A   1
LEU A 218
LEU A 285
VAL A 235
VAL A 252
 None
 0.98A 4yb6A-1nrwA:
undetectable
4yb6D-1nrwA:
undetectable		 4yb6A-1nrwA:
23.85
4yb6D-1nrwA:
23.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YB6_E_HISE302_0
(ATP
PHOSPHORIBOSYLTRANSF
ERASE)		 1nrw HYPOTHETICAL
PROTEIN, HALOACID
DEHALOGENASE-LIKE
HYDROLASE
(Bacillus
subtilis) 		5 / 10 MET A   1
LEU A 218
LEU A 285
VAL A 235
VAL A 252
 None
 1.00A 4yb6D-1nrwA:
undetectable
4yb6E-1nrwA:
undetectable		 4yb6D-1nrwA:
23.85
4yb6E-1nrwA:
23.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YB6_F_HISF302_0
(ATP
PHOSPHORIBOSYLTRANSF
ERASE)		 1nrw HYPOTHETICAL
PROTEIN, HALOACID
DEHALOGENASE-LIKE
HYDROLASE
(Bacillus
subtilis) 		5 / 10 MET A   1
LEU A 218
LEU A 285
VAL A 235
VAL A 252
 None
 0.98A 4yb6B-1nrwA:
undetectable
4yb6F-1nrwA:
undetectable		 4yb6B-1nrwA:
23.85
4yb6F-1nrwA:
23.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B2Q_A_ACTA1728_0
(CRISPR-ASSOCIATED
ENDONUCLEASE CAS9)		 1nrw HYPOTHETICAL
PROTEIN, HALOACID
DEHALOGENASE-LIKE
HYDROLASE
(Bacillus
subtilis) 		3 / 3 ASN A 204
SER A 200
ARG A  43
 None
PO4  A 900 ( 4.2A)
None
 0.95A 5b2qA-1nrwA:
0.4		 5b2qA-1nrwA:
10.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CDN_O_EVPO2101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT
B,DNA GYRASE SUBUNIT
B)		 1nrw HYPOTHETICAL
PROTEIN, HALOACID
DEHALOGENASE-LIKE
HYDROLASE
(Bacillus
subtilis) 		4 / 6 SER A 128
GLU A 202
ASP A  47
GLY A  42
 None
None
None
PO4  A 900 (-3.8A)
 0.92A 5cdnC-1nrwA:
1.6
5cdnD-1nrwA:
undetectable		 5cdnC-1nrwA:
22.11
5cdnD-1nrwA:
22.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CDN_P_EVPP2101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT
B,DNA GYRASE SUBUNIT
B)		 1nrw HYPOTHETICAL
PROTEIN, HALOACID
DEHALOGENASE-LIKE
HYDROLASE
(Bacillus
subtilis) 		4 / 6 SER A 128
GLU A 202
ASP A  47
GLY A  42
 None
None
None
PO4  A 900 (-3.8A)
 0.92A 5cdnT-1nrwA:
1.1
5cdnU-1nrwA:
undetectable		 5cdnT-1nrwA:
22.11
5cdnU-1nrwA:
22.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IQE_D_NMYD600_1
(BIFUNCTIONAL AAC/APH)		 1nrw HYPOTHETICAL
PROTEIN, HALOACID
DEHALOGENASE-LIKE
HYDROLASE
(Bacillus
subtilis) 		5 / 12 ASP A   7
SER A 238
ASN A 240
GLU A 206
GLU A 122
 PO4  A 900 ( 2.6A)
CA  A 903 (-2.5A)
PO4  A 900 (-3.6A)
None
None
 1.27A 5iqeD-1nrwA:
0.0		 5iqeD-1nrwA:
22.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KBW_B_RBFB201_1
(RIBOFLAVIN
TRANSPORTER RIBU)		 1nrw HYPOTHETICAL
PROTEIN, HALOACID
DEHALOGENASE-LIKE
HYDROLASE
(Bacillus
subtilis) 		5 / 12 GLU A 132
GLY A  10
ALA A 278
ASN A  23
VAL A  19
 None
CA  A 903 ( 4.4A)
None
None
None
 1.25A 5kbwB-1nrwA:
undetectable		 5kbwB-1nrwA:
19.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ND2_B_TA1B601_1
(TUBULIN BETA-2B
CHAIN)		 1nrw HYPOTHETICAL
PROTEIN, HALOACID
DEHALOGENASE-LIKE
HYDROLASE
(Bacillus
subtilis) 		5 / 12 VAL A 121
ASP A 124
GLU A 122
PHE A 104
ARG A  43
 None
 1.18A 5nd2B-1nrwA:
4.0		 5nd2B-1nrwA:
19.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VKQ_A_PCFA1808_0
(NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L)		 1nrw HYPOTHETICAL
PROTEIN, HALOACID
DEHALOGENASE-LIKE
HYDROLASE
(Bacillus
subtilis) 		4 / 5 LYS A 219
ALA A 222
LEU A 225
LEU A 229
 None
 0.82A 5vkqA-1nrwA:
0.0
5vkqD-1nrwA:
0.0		 5vkqA-1nrwA:
11.46
5vkqD-1nrwA:
11.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VKQ_B_PCFB1805_0
(NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L)		 1nrw HYPOTHETICAL
PROTEIN, HALOACID
DEHALOGENASE-LIKE
HYDROLASE
(Bacillus
subtilis) 		4 / 5 LEU A 229
LYS A 219
ALA A 222
LEU A 225
 None
 0.82A 5vkqA-1nrwA:
0.0
5vkqB-1nrwA:
0.0		 5vkqA-1nrwA:
11.46
5vkqB-1nrwA:
11.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VKQ_C_PCFC1806_0
(NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L)		 1nrw HYPOTHETICAL
PROTEIN, HALOACID
DEHALOGENASE-LIKE
HYDROLASE
(Bacillus
subtilis) 		4 / 5 LEU A 229
LYS A 219
ALA A 222
LEU A 225
 None
 0.81A 5vkqB-1nrwA:
0.0
5vkqC-1nrwA:
0.0		 5vkqB-1nrwA:
11.46
5vkqC-1nrwA:
11.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VKQ_D_PCFD1806_0
(NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L)		 1nrw HYPOTHETICAL
PROTEIN, HALOACID
DEHALOGENASE-LIKE
HYDROLASE
(Bacillus
subtilis) 		4 / 5 LEU A 229
LYS A 219
ALA A 222
LEU A 225
 None
 0.84A 5vkqC-1nrwA:
0.0
5vkqD-1nrwA:
0.0		 5vkqC-1nrwA:
11.46
5vkqD-1nrwA:
11.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VLM_B_CVIB301_0
(REGULATORY PROTEIN
TETR)		 1nrw HYPOTHETICAL
PROTEIN, HALOACID
DEHALOGENASE-LIKE
HYDROLASE
(Bacillus
subtilis) 		5 / 12 MET A 281
MET A 280
GLU A  24
VAL A  39
PHE A  52
 None
 1.35A 5vlmB-1nrwA:
undetectable		 5vlmB-1nrwA:
21.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VLM_E_CVIE301_0
(REGULATORY PROTEIN
TETR)		 1nrw HYPOTHETICAL
PROTEIN, HALOACID
DEHALOGENASE-LIKE
HYDROLASE
(Bacillus
subtilis) 		5 / 12 MET A 281
MET A 280
GLU A  24
VAL A  39
PHE A  52
 None
 1.16A 5vlmE-1nrwA:
undetectable		 5vlmE-1nrwA:
21.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YOD_F_BEZF201_0
(NS3 PROTEASE)		 1nrw HYPOTHETICAL
PROTEIN, HALOACID
DEHALOGENASE-LIKE
HYDROLASE
(Bacillus
subtilis) 		4 / 5 HIS A  70
ALA A  44
SER A  63
TYR A 170
 None
 1.35A 5yodF-1nrwA:
undetectable		 5yodF-1nrwA:
20.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6C5U_A_RIOA600_0
(BIFUNCTIONAL AAC/APH)		 1nrw HYPOTHETICAL
PROTEIN, HALOACID
DEHALOGENASE-LIKE
HYDROLASE
(Bacillus
subtilis) 		5 / 10 ASP A   7
SER A 238
ASN A 240
GLU A 206
GLU A 122
 PO4  A 900 ( 2.6A)
CA  A 903 (-2.5A)
PO4  A 900 (-3.6A)
None
None
 1.30A 6c5uA-1nrwA:
1.5		 6c5uA-1nrwA:
22.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6C5U_D_RIOD600_0
(BIFUNCTIONAL AAC/APH)		 1nrw HYPOTHETICAL
PROTEIN, HALOACID
DEHALOGENASE-LIKE
HYDROLASE
(Bacillus
subtilis) 		5 / 10 ASP A   7
SER A 238
ASN A 240
GLU A 206
GLU A 122
 PO4  A 900 ( 2.6A)
CA  A 903 (-2.5A)
PO4  A 900 (-3.6A)
None
None
 1.26A 6c5uD-1nrwA:
0.0		 6c5uD-1nrwA:
22.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MDQ_A_TESA604_0
(SERUM ALBUMIN)		 1nrw HYPOTHETICAL
PROTEIN, HALOACID
DEHALOGENASE-LIKE
HYDROLASE
(Bacillus
subtilis) 		4 / 8 ALA A 248
GLY A 215
LEU A 218
ALA A   5
 None
 0.72A 6mdqA-1nrwA:
2.0		 6mdqA-1nrwA:
15.71