SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1nsl'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KP6_B_SALB3003_1
(TRANSCRIPTIONAL
REGULATOR TCAR)		 1nsl PROBABLE
ACETYLTRANSFERASE
(Bacillus
subtilis) 		4 / 6 ILE A  96
VAL A 130
HIS A  85
LEU A  87
 None
 0.61A 3kp6A-1nslA:
undetectable
3kp6B-1nslA:
undetectable		 3kp6A-1nslA:
25.76
3kp6B-1nslA:
25.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P4W_B_DSFB319_1
(GLR4197 PROTEIN)		 1nsl PROBABLE
ACETYLTRANSFERASE
(Bacillus
subtilis) 		5 / 9 ILE A 110
ILE A  82
VAL A 144
ILE A  96
ILE A 132
 CL  A 184 ( 4.2A)
None
None
None
None
 1.05A 3p4wB-1nslA:
0.0		 3p4wB-1nslA:
19.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P4W_D_DSFD319_1
(GLR4197 PROTEIN)		 1nsl PROBABLE
ACETYLTRANSFERASE
(Bacillus
subtilis) 		5 / 10 ILE A 110
ILE A  82
VAL A 144
ILE A  96
ILE A 132
 CL  A 184 ( 4.2A)
None
None
None
None
 1.05A 3p4wD-1nslA:
0.0		 3p4wD-1nslA:
19.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P4W_E_DSFE319_1
(GLR4197 PROTEIN)		 1nsl PROBABLE
ACETYLTRANSFERASE
(Bacillus
subtilis) 		5 / 10 ILE A 110
ILE A  82
VAL A 144
ILE A  96
ILE A 132
 CL  A 184 ( 4.2A)
None
None
None
None
 1.04A 3p4wE-1nslA:
0.0		 3p4wE-1nslA:
19.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N49_A_SAMA601_0
(CAP-SPECIFIC MRNA
(NUCLEOSIDE-2'-O-)-M
ETHYLTRANSFERASE 1)		 1nsl PROBABLE
ACETYLTRANSFERASE
(Bacillus
subtilis) 		5 / 12 ALA A 134
PRO A 145
THR A 111
ILE A 109
LEU A  72
 None
None
CL  A 184 (-4.6A)
None
None
 1.01A 4n49A-1nslA:
undetectable		 4n49A-1nslA:
16.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UBS_A_DIFA503_1
(PENTALENIC ACID
SYNTHASE)		 1nsl PROBABLE
ACETYLTRANSFERASE
(Bacillus
subtilis) 		4 / 7 ALA A 101
LEU A  26
LEU A  23
ILE A 100
 None
 0.80A 4ubsA-1nslA:
undetectable		 4ubsA-1nslA:
19.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KC0_A_RBFA303_2
(RIBOFLAVIN
TRANSPORTER RIBU)		 1nsl PROBABLE
ACETYLTRANSFERASE
(Bacillus
subtilis) 		3 / 3 LYS A 116
LEU A 125
ILE A  68
 None
 0.76A 5kc0A-1nslA:
undetectable		 5kc0A-1nslA:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KC4_A_RBFA201_2
(RIBOFLAVIN
TRANSPORTER RIBU)		 1nsl PROBABLE
ACETYLTRANSFERASE
(Bacillus
subtilis) 		3 / 3 LYS A 116
LEU A 125
ILE A  68
 None
 0.68A 5kc4A-1nslA:
undetectable		 5kc4A-1nslA:
19.05