SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1nu2'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KI7_A_ID2A1_0
(THYMIDINE KINASE)		 1nu2 DISABLED HOMOLOG 1
(Mus
musculus) 		5 / 12 GLU A 169
ILE A 161
ALA A 174
ARG A 167
GLU A 163
 None
 1.31A 1ki7A-1nu2A:
undetectable		 1ki7A-1nu2A:
18.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZGY_A_BRLA503_2
(PEROXISOME
PROLIFERATOR
ACTIVATED RECEPTOR
GAMMA)		 1nu2 DISABLED HOMOLOG 1
(Mus
musculus) 		4 / 5 ILE A 116
ILE A  85
ILE A  89
LEU A  68
 None
 0.94A 1zgyA-1nu2A:
0.0		 1zgyA-1nu2A:
22.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Z0Y_A_SAMA300_0
(PUTATIVE
UNCHARACTERIZED
PROTEIN TTHA0657)		 1nu2 DISABLED HOMOLOG 1
(Mus
musculus) 		5 / 9 VAL A  40
GLY A  39
GLY A  37
ILE A  32
LEU A  31
 None
 0.97A 2z0yA-1nu2A:
undetectable		 2z0yA-1nu2A:
19.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJW_C_SVRC507_1
(PHOSPHOLIPASE A2)		 1nu2 DISABLED HOMOLOG 1
(Mus
musculus) 		4 / 7 VAL A  71
VAL A  72
GLY A  74
LYS A  67
 None
 0.97A 3bjwC-1nu2A:
0.0		 3bjwC-1nu2A:
18.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJW_G_SVRG506_1
(PHOSPHOLIPASE A2)		 1nu2 DISABLED HOMOLOG 1
(Mus
musculus) 		4 / 8 VAL A  71
VAL A  72
GLY A  74
LYS A  67
 None
 0.86A 3bjwA-1nu2A:
undetectable		 3bjwA-1nu2A:
18.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HS4_A_AZMA702_1
(CARBONIC ANHYDRASE 2)		 1nu2 DISABLED HOMOLOG 1
(Mus
musculus) 		4 / 7 VAL A  40
TYR A  42
GLU A 148
PRO A 149
 None
 1.14A 3hs4A-1nu2A:
undetectable		 3hs4A-1nu2A:
22.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V4T_A_ACTA502_0
(UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE)		 1nu2 DISABLED HOMOLOG 1
(Mus
musculus) 		4 / 5 VAL A 129
SER A 114
GLY A  57
ARG A  56
 None
 1.17A 3v4tA-1nu2A:
undetectable
3v4tD-1nu2A:
undetectable		 3v4tA-1nu2A:
17.68
3v4tD-1nu2A:
17.68