SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1nui'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q63_A_1UNA1001_2
(PROTEASE RETROPEPSIN)		 1nui DNA PRIMASE/HELICASE
(Escherichia
virus
T7) 		3 / 3 ARG A 124
ASN A  70
THR A 133
 None
 0.83A 2q63A-1nuiA:
undetectable		 2q63A-1nuiA:
15.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VE3_A_REAA1445_1
(PUTATIVE CYTOCHROME
P450 120)		 1nui DNA PRIMASE/HELICASE
(Escherichia
virus
T7) 		5 / 12 THR A 188
ALA A 219
LEU A 223
PHE A 196
GLY A 158
 None
 1.06A 2ve3A-1nuiA:
0.0		 2ve3A-1nuiA:
18.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJW_B_SVRB512_2
(PHOSPHOLIPASE A2)		 1nui DNA PRIMASE/HELICASE
(Escherichia
virus
T7) 		4 / 7 LYS A  88
GLN A  92
GLY A  95
LEU A 146
 None
 0.90A 3bjwB-1nuiA:
undetectable		 3bjwB-1nuiA:
17.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CE6_B_ADNB500_2
(ADENOSYLHOMOCYSTEINA
SE)		 1nui DNA PRIMASE/HELICASE
(Escherichia
virus
T7) 		4 / 5 LEU A  81
GLN A  92
THR A 164
HIS A 242
 None
 1.33A 3ce6B-1nuiA:
undetectable		 3ce6B-1nuiA:
20.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HEG_A_BAXA1_2
(MITOGEN-ACTIVATED
PROTEIN KINASE 14)		 1nui DNA PRIMASE/HELICASE
(Escherichia
virus
T7) 		4 / 6 VAL A 154
ILE A 250
ILE A 203
LEU A 204
 None
 0.81A 3hegA-1nuiA:
undetectable		 3hegA-1nuiA:
21.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QGK_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 1nui DNA PRIMASE/HELICASE
(Escherichia
virus
T7) 		3 / 3 VAL A 123
TYR A 106
GLN A 107
 None
 0.57A 5qgkA-1nuiA:
0.0		 5qgkA-1nuiA:
19.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QGR_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 1nui DNA PRIMASE/HELICASE
(Escherichia
virus
T7) 		3 / 3 VAL A 123
TYR A 106
GLN A 107
 None
 0.56A 5qgrA-1nuiA:
0.0		 5qgrA-1nuiA:
19.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QGT_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 1nui DNA PRIMASE/HELICASE
(Escherichia
virus
T7) 		3 / 3 VAL A 123
TYR A 106
GLN A 107
 None
 0.61A 5qgtA-1nuiA:
0.0		 5qgtA-1nuiA:
19.01