SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1nun'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)	View	Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1N5X_A_TEIA3006_1 (XANTHINE DEHYDROGENASE)	1nun	FIBROBLAST GROWTH FACTOR RECEPTOR 2 ISOFORM 2 (Homo sapiens)	5 / 12	LYS B 292 LEU B 327 THR B 268 VAL B 357 ALA B 266	None	1.18A	1n5xA-1nunB: undetectable	1n5xA-1nunB: 10.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1N5X_B_TEIB4006_1 (XANTHINE DEHYDROGENASE)	1nun	FIBROBLAST GROWTH FACTOR RECEPTOR 2 ISOFORM 2 (Homo sapiens)	5 / 12	LYS B 292 LEU B 327 THR B 268 VAL B 357 ALA B 266	None	1.18A	1n5xB-1nunB: undetectable	1n5xB-1nunB: 10.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4F93_B_SANB3004_1 (U5 SMALL NUCLEAR RIBONUCLEOPROTEIN 200 KDA HELICASE)	1nun	FIBROBLAST GROWTH FACTOR RECEPTOR 2 ISOFORM 2 (Homo sapiens)	4 / 8	TRP B 214 ASN B 235 GLY B 238 SER B 239	None	0.82A	4f93B-1nunB: 5.1	4f93B-1nunB: 8.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5HBS_A_RTLA201_1 (RETINOL-BINDING PROTEIN 1)	1nun	FIBROBLAST GROWTH FACTOR-10 (Homo sapiens)	4 / 8	LEU A 132 LEU A 180 THR A 192 TYR A 177	None	1.18A	5hbsA-1nunA: undetectable	5hbsA-1nunA: 21.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5JO9_A_SORA302_0 (RIBITOL 2-DEHYDROGENASE)	1nun	FIBROBLAST GROWTH FACTOR RECEPTOR 2 ISOFORM 2 (Homo sapiens)	5 / 12	LEU B 327 THR B 268 VAL B 324 PHE B 276 LEU B 355	None	1.22A	5jo9A-1nunB: undetectable	5jo9A-1nunB: 20.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5OS7_A_ACTA402_0 (CASEIN KINASE II SUBUNIT ALPHA)	1nun	FIBROBLAST GROWTH FACTOR RECEPTOR 2 ISOFORM 2 (Homo sapiens)	3 / 3	HIS B 213 SER B 215 LYS B 176	None	1.44A	5os7A-1nunB: undetectable	5os7A-1nunB: 21.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5TZO_B_7V7B202_1 (ENDO-1,4-BETA-XYLANA SE A)	1nun	FIBROBLAST GROWTH FACTOR-10 (Homo sapiens)	4 / 8	THR A 197 TYR A 161 THR A 163 ARG A 194	None	1.40A	5tzoB-1nunA: undetectable	5tzoB-1nunA: 18.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6GMD_B_ACTB402_0 (CASEIN KINASE II SUBUNIT ALPHA)	1nun	FIBROBLAST GROWTH FACTOR RECEPTOR 2 ISOFORM 2 (Homo sapiens)	3 / 3	HIS B 213 SER B 215 LYS B 176	None	1.44A	6gmdB-1nunB: undetectable	6gmdB-1nunB: 21.56

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1N5X_A_TEIA3006_1","XANTHINE DEHYDROGENASE","1nun","FIBROBLAST GROWTH FACTOR RECEPTOR 2 ISOFORM 2","Homo sapiens",5,"LYS B 292;LEU B 327;THR B 268;VAL B 357;ALA B 266","None","1.18A","1n5xA-1nunB:undetectable","1n5xA-1nunB:10.61"],["1N5X_B_TEIB4006_1","XANTHINE DEHYDROGENASE","1nun","FIBROBLAST GROWTH FACTOR RECEPTOR 2 ISOFORM 2","Homo sapiens",5,"LYS B 292;LEU B 327;THR B 268;VAL B 357;ALA B 266","None","1.18A","1n5xB-1nunB:undetectable","1n5xB-1nunB:10.61"],["4F93_B_SANB3004_1","U5 SMALL NUCLEAR RIBONUCLEOPROTEIN 200 KDA HELICASE","1nun","FIBROBLAST GROWTH FACTOR RECEPTOR 2 ISOFORM 2","Homo sapiens",4,"TRP B 214;ASN B 235;GLY B 238;SER B 239","None","0.82A","4f93B-1nunB:5.1","4f93B-1nunB:8.50"],["5HBS_A_RTLA201_1","RETINOL-BINDING PROTEIN 1","1nun","FIBROBLAST GROWTH FACTOR-10","Homo sapiens",4,"LEU A 132;LEU A 180;THR A 192;TYR A 177","None","1.18A","5hbsA-1nunA:undetectable","5hbsA-1nunA:21.34"],["5JO9_A_SORA302_0","RIBITOL 2-DEHYDROGENASE","1nun","FIBROBLAST GROWTH FACTOR RECEPTOR 2 ISOFORM 2","Homo sapiens",5,"LEU B 327;THR B 268;VAL B 324;PHE B 276;LEU B 355","None","1.22A","5jo9A-1nunB:undetectable","5jo9A-1nunB:20.56"],["5OS7_A_ACTA402_0","CASEIN KINASE II SUBUNIT ALPHA","1nun","FIBROBLAST GROWTH FACTOR RECEPTOR 2 ISOFORM 2","Homo sapiens",3,"HIS B 213;SER B 215;LYS B 176","None","1.44A","5os7A-1nunB:undetectable","5os7A-1nunB:21.56"],["5TZO_B_7V7B202_1","ENDO-1,4-BETA-XYLANASE A","1nun","FIBROBLAST GROWTH FACTOR-10","Homo sapiens",4,"THR A 197;TYR A 161;THR A 163;ARG A 194","None","1.40A","5tzoB-1nunA:undetectable","5tzoB-1nunA:18.32"],["6GMD_B_ACTB402_0","CASEIN KINASE II SUBUNIT ALPHA","1nun","FIBROBLAST GROWTH FACTOR RECEPTOR 2 ISOFORM 2","Homo sapiens",3,"HIS B 213;SER B 215;LYS B 176","None","1.44A","6gmdB-1nunB:undetectable","6gmdB-1nunB:21.56"]]