SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1nvj'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1B2I_A_AMHA84_1
(PROTEIN
(PLASMINOGEN))		 1nvj MOLYBDOPTERIN
CONVERTING FACTOR
SUBUNIT 2
(Escherichia
coli) 		4 / 7 TYR A 117
GLU A  65
PHE A 113
ARG A  73
 None
 1.48A 1b2iA-1nvjA:
undetectable		 1b2iA-1nvjA:
18.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HXB_A_ROCA100_3
(HIV-1 PROTEASE)		 1nvj MOLYBDOPTERIN
CONVERTING FACTOR
SUBUNIT 2
(Escherichia
coli) 		5 / 12 ALA A  64
VAL A  81
ILE A 114
VAL A   8
ILE A   6
 None
 1.05A 1hxbB-1nvjA:
undetectable		 1hxbB-1nvjA:
18.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X2I_A_QPSA1060_1
(ALPHA-1,4-GLUCAN
LYASE ISOZYME 1)		 1nvj MOLYBDOPTERIN
CONVERTING FACTOR
SUBUNIT 2
(Escherichia
coli) 		5 / 12 VAL A  95
PHE A  96
THR A   4
VAL A  99
GLY A 111
 None
 1.19A 2x2iA-1nvjA:
undetectable		 2x2iA-1nvjA:
8.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X2I_C_QPSC1060_1
(ALPHA-1,4-GLUCAN
LYASE ISOZYME 1)		 1nvj MOLYBDOPTERIN
CONVERTING FACTOR
SUBUNIT 2
(Escherichia
coli) 		5 / 12 VAL A  95
PHE A  96
THR A   4
VAL A  99
GLY A 111
 None
 1.19A 2x2iC-1nvjA:
undetectable		 2x2iC-1nvjA:
8.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ROX_A_TEPA266_1
(APOLIPOPROTEIN
A-I-BINDING PROTEIN)		 1nvj MOLYBDOPTERIN
CONVERTING FACTOR
SUBUNIT 2
(Escherichia
coli) 		4 / 8 ALA A  64
VAL A  67
ASP A  68
THR A   4
 None
 0.75A 3roxA-1nvjA:
undetectable		 3roxA-1nvjA:
20.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MVN_B_PFLB410_1
(PROTON-GATED ION
CHANNEL)		 1nvj MOLYBDOPTERIN
CONVERTING FACTOR
SUBUNIT 2
(Escherichia
coli) 		5 / 9 PRO A  56
ILE A  85
VAL A   8
TYR A  55
THR A  59
 None
 1.48A 5mvnB-1nvjA:
undetectable		 5mvnB-1nvjA:
22.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MVN_C_PFLC407_1
(PROTON-GATED ION
CHANNEL)		 1nvj MOLYBDOPTERIN
CONVERTING FACTOR
SUBUNIT 2
(Escherichia
coli) 		5 / 9 PRO A  56
ILE A  85
VAL A   8
TYR A  55
THR A  59
 None
 1.47A 5mvnC-1nvjA:
undetectable		 5mvnC-1nvjA:
22.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MVN_D_PFLD410_1
(PROTON-GATED ION
CHANNEL)		 1nvj MOLYBDOPTERIN
CONVERTING FACTOR
SUBUNIT 2
(Escherichia
coli) 		5 / 10 PRO A  56
ILE A  85
VAL A   8
TYR A  55
THR A  59
 None
 1.48A 5mvnD-1nvjA:
undetectable		 5mvnD-1nvjA:
22.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MZR_A_PFLA412_1
(PROTON-GATED ION
CHANNEL)		 1nvj MOLYBDOPTERIN
CONVERTING FACTOR
SUBUNIT 2
(Escherichia
coli) 		5 / 10 PRO A  56
ILE A  85
VAL A   8
TYR A  55
THR A  59
 None
 1.46A 5mzrA-1nvjA:
0.0		 5mzrA-1nvjA:
22.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MZR_C_PFLC409_1
(PROTON-GATED ION
CHANNEL)		 1nvj MOLYBDOPTERIN
CONVERTING FACTOR
SUBUNIT 2
(Escherichia
coli) 		5 / 10 PRO A  56
ILE A  85
VAL A   8
TYR A  55
THR A  59
 None
 1.44A 5mzrC-1nvjA:
undetectable		 5mzrC-1nvjA:
22.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MZR_D_PFLD410_1
(PROTON-GATED ION
CHANNEL)		 1nvj MOLYBDOPTERIN
CONVERTING FACTOR
SUBUNIT 2
(Escherichia
coli) 		5 / 9 PRO A  56
ILE A  85
VAL A   8
TYR A  55
THR A  59
 None
 1.49A 5mzrD-1nvjA:
0.0		 5mzrD-1nvjA:
22.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VKQ_B_PCFB1804_0
(NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L)		 1nvj MOLYBDOPTERIN
CONVERTING FACTOR
SUBUNIT 2
(Escherichia
coli) 		5 / 8 GLY A  77
LEU A  76
LEU A  63
VAL A  67
ILE A  82
 GOL  A 141 ( 3.7A)
None
None
None
None
 1.26A 5vkqB-1nvjA:
undetectable
5vkqC-1nvjA:
undetectable		 5vkqB-1nvjA:
6.27
5vkqC-1nvjA:
6.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BER_A_DVAA2_0
(E(DVA)DP(DGL)(DHI)(D
PR)N(DAL)(DPR))		 1nvj MOLYBDOPTERIN
CONVERTING FACTOR
SUBUNIT 2
(Escherichia
coli) 		3 / 3 GLU A  87
ASP A  92
PRO A  90
 None
 0.73A 6berA-1nvjA:
undetectable		 6berA-1nvjA:
7.44