SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1nxb'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YKI_A_NFZA1219_1
(OXYGEN-INSENSITIVE
NAD(P)H
NITROREDUCTASE)		 1nxb NEUROTOXIN B
(Laticauda
semifasciata) 		4 / 8 TYR A  25
ASN A  61
GLY A  40
THR A  13
 None
 1.02A 1ykiA-1nxbA:
undetectable
1ykiB-1nxbA:
undetectable		 1ykiA-1nxbA:
11.85
1ykiB-1nxbA:
11.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YKI_B_NFZB2219_1
(OXYGEN-INSENSITIVE
NAD(P)H
NITROREDUCTASE)		 1nxb NEUROTOXIN B
(Laticauda
semifasciata) 		4 / 8 THR A  13
TYR A  25
ASN A  61
GLY A  40
 None
 1.02A 1ykiA-1nxbA:
undetectable
1ykiB-1nxbA:
undetectable		 1ykiA-1nxbA:
11.85
1ykiB-1nxbA:
11.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YKI_C_NFZC3219_1
(OXYGEN-INSENSITIVE
NAD(P)H
NITROREDUCTASE)		 1nxb NEUROTOXIN B
(Laticauda
semifasciata) 		4 / 8 TYR A  25
ASN A  61
GLY A  40
THR A  13
 None
 0.98A 1ykiC-1nxbA:
undetectable
1ykiD-1nxbA:
undetectable		 1ykiC-1nxbA:
11.85
1ykiD-1nxbA:
11.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YKI_D_NFZD4219_1
(OXYGEN-INSENSITIVE
NAD(P)H
NITROREDUCTASE)		 1nxb NEUROTOXIN B
(Laticauda
semifasciata) 		4 / 8 THR A  13
TYR A  25
ASN A  61
GLY A  40
 None
 1.02A 1ykiC-1nxbA:
undetectable
1ykiD-1nxbA:
undetectable		 1ykiC-1nxbA:
11.85
1ykiD-1nxbA:
11.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_F_W9TF512_1
(HEMOLYTIC LECTIN
CEL-III)		 1nxb NEUROTOXIN B
(Laticauda
semifasciata) 		4 / 6 THR A  13
ASN A   5
GLY A  40
ILE A  37
 None
SO4  A  64 (-4.1A)
None
None
 0.98A 3w9tF-1nxbA:
undetectable		 3w9tF-1nxbA:
9.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6JMJ_A_ASCA201_0
(PHOSPHOPANTETHEINE
ADENYLYLTRANSFERASE)		 1nxb NEUROTOXIN B
(Laticauda
semifasciata) 		4 / 5 GLY A  34
THR A  35
SER A   9
SER A   8
 None
 1.07A 6jmjA-1nxbA:
undetectable		 6jmjA-1nxbA:
16.46