SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1nxi'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1T9W_A_NFNA6002_1
(ACRIFLAVINE
RESISTANCE PROTEIN B)		 1nxi CONSERVED
HYPOTHETICAL PROTEIN
VC0424
(Vibrio
cholerae) 		4 / 7 MET A  63
PHE A  65
ASN A 106
GLU A  99
 None
 1.37A 1t9wA-1nxiA:
3.9		 1t9wA-1nxiA:
8.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MJ8_A_SPMA202_1
(SPERMIDINE
N1-ACETYLTRANSFERASE)		 1nxi CONSERVED
HYPOTHETICAL PROTEIN
VC0424
(Vibrio
cholerae) 		4 / 8 ILE A  16
GLU A  20
GLN A  17
ILE A  97
 None
 0.90A 4mj8A-1nxiA:
undetectable		 4mj8A-1nxiA:
22.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R3A_A_RBFA402_2
(BLUE-LIGHT-ACTIVATED
HISTIDINE KINASE 2)		 1nxi CONSERVED
HYPOTHETICAL PROTEIN
VC0424
(Vibrio
cholerae) 		5 / 8 GLU A  42
LEU A  96
VAL A 101
LEU A 104
GLY A  64
 None
 1.47A 4r3aA-1nxiA:
undetectable		 4r3aA-1nxiA:
20.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z90_F_4LEF402_1
(GAMMA-AMINOBUTYRIC-A
CID RECEPTOR SUBUNIT
BETA-1)		 1nxi CONSERVED
HYPOTHETICAL PROTEIN
VC0424
(Vibrio
cholerae) 		5 / 7 LEU A 104
ALA A  60
LEU A 107
ALA A  56
ALA A  86
 None
 1.02A 4z90F-1nxiA:
undetectable
4z90G-1nxiA:
undetectable
4z90H-1nxiA:
undetectable
4z90J-1nxiA:
undetectable		 4z90F-1nxiA:
16.67
4z90G-1nxiA:
16.67
4z90H-1nxiA:
16.67
4z90J-1nxiA:
16.67