SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1nxk'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1E06_B_IPBB600_0 (ODORANT-BINDING PROTEIN)	1nxk	MAP KINASE-ACTIVATED PROTEIN KINASE 2 (Homo sapiens)	4 / 4	ILE A 170 MET A 253 VAL A 331 GLY A 171	None	1.31A	1e06B-1nxkA: 0.4	1e06B-1nxkA: 19.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1FMO_E_ADNE351_1 (CAMP-DEPENDENT PROTEIN KINASE)	1nxk	MAP KINASE-ACTIVATED PROTEIN KINASE 2 (Homo sapiens)	8 / 12	LEU A 70 GLY A 71 VAL A 78 ALA A 91 ASN A 191 LEU A 193 THR A 206 ASP A 207	STU A 401 (-3.9A) STU A 401 (-3.6A) STU A 401 (-4.7A) STU A 401 (-3.4A) STU A 401 (-4.5A) STU A 401 (-4.7A) STU A 401 (-3.2A) STU A 401 (-3.6A)	0.72A	1fmoE-1nxkA: 22.4	1fmoE-1nxkA: 27.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1FMO_E_ADNE351_1 (CAMP-DEPENDENT PROTEIN KINASE)	1nxk	MAP KINASE-ACTIVATED PROTEIN KINASE 2 (Homo sapiens)	8 / 12	LEU A 70 GLY A 71 VAL A 78 ALA A 91 VAL A 118 ASN A 191 THR A 206 ASP A 207	STU A 401 (-3.9A) STU A 401 (-3.6A) STU A 401 (-4.7A) STU A 401 (-3.4A) None STU A 401 (-4.5A) STU A 401 (-3.2A) STU A 401 (-3.6A)	0.64A	1fmoE-1nxkA: 22.4	1fmoE-1nxkA: 27.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1MUO_A_ADNA1_1 (AURORA-RELATED KINASE 1)	1nxk	MAP KINASE-ACTIVATED PROTEIN KINASE 2 (Homo sapiens)	5 / 9	LEU A 70 GLY A 71 VAL A 78 ALA A 91 LEU A 193	STU A 401 (-3.9A) STU A 401 (-3.6A) STU A 401 (-4.7A) STU A 401 (-3.4A) STU A 401 (-4.7A)	0.51A	1muoA-1nxkA: 7.8	1muoA-1nxkA: 28.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1RA8_A_FOLA161_1 (DIHYDROFOLATE REDUCTASE)	1nxk	MAP KINASE-ACTIVATED PROTEIN KINASE 2 (Homo sapiens)	3 / 3	ASP A 97 LYS A 100 ARG A 103	None	1.18A	1ra8A-1nxkA: undetectable	1ra8A-1nxkA: 17.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1RA8_A_FOLA161_1 (DIHYDROFOLATE REDUCTASE)	1nxk	MAP KINASE-ACTIVATED PROTEIN KINASE 2 (Homo sapiens)	3 / 3	ASP A 245 LYS A 212 ARG A 103	None	1.19A	1ra8A-1nxkA: undetectable	1ra8A-1nxkA: 17.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1S8F_A_BEZA1501_0 (RAS-RELATED PROTEIN RAB-9A)	1nxk	MAP KINASE-ACTIVATED PROTEIN KINASE 2 (Homo sapiens)	4 / 5	ILE A 302 TRP A 291 LEU A 306 PRO A 262	None	1.35A	1s8fA-1nxkA: 0.1 1s8fB-1nxkA: 0.0	1s8fA-1nxkA: 19.90 1s8fB-1nxkA: 19.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2FUM_A_MIXA539_1 (PROBABLE SERINE/THREONINE-PRO TEIN KINASE PKNB)	1nxk	MAP KINASE-ACTIVATED PROTEIN KINASE 2 (Homo sapiens)	8 / 12	LEU A 70 GLY A 71 VAL A 78 ALA A 91 ASP A 186 LYS A 188 ASN A 191 ASP A 207	STU A 401 (-3.9A) STU A 401 (-3.6A) STU A 401 (-4.7A) STU A 401 (-3.4A) None None STU A 401 (-4.5A) STU A 401 (-3.6A)	0.72A	2fumA-1nxkA: 23.4	2fumA-1nxkA: 24.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2FUM_B_MIXB1539_1 (PROBABLE SERINE/THREONINE-PRO TEIN KINASE PKNB)	1nxk	MAP KINASE-ACTIVATED PROTEIN KINASE 2 (Homo sapiens)	8 / 12	LEU A 70 GLY A 71 VAL A 78 ALA A 91 MET A 138 LYS A 188 ASN A 191 ASP A 207	STU A 401 (-3.9A) STU A 401 (-3.6A) STU A 401 (-4.7A) STU A 401 (-3.4A) STU A 401 (-3.2A) None STU A 401 (-4.5A) STU A 401 (-3.6A)	0.76A	2fumB-1nxkA: 23.4	2fumB-1nxkA: 24.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2FUM_C_MIXC2539_1 (PROBABLE SERINE/THREONINE-PRO TEIN KINASE PKNB)	1nxk	MAP KINASE-ACTIVATED PROTEIN KINASE 2 (Homo sapiens)	6 / 12	LEU A 70 GLY A 71 VAL A 78 ALA A 91 MET A 138 ASN A 191	STU A 401 (-3.9A) STU A 401 (-3.6A) STU A 401 (-4.7A) STU A 401 (-3.4A) STU A 401 (-3.2A) STU A 401 (-4.5A)	0.54A	2fumC-1nxkA: 21.6	2fumC-1nxkA: 24.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2FUM_D_MIXD3539_1 (PROBABLE SERINE/THREONINE-PRO TEIN KINASE PKNB)	1nxk	MAP KINASE-ACTIVATED PROTEIN KINASE 2 (Homo sapiens)	8 / 12	LEU A 70 GLY A 71 VAL A 78 ALA A 91 MET A 138 LYS A 188 ASN A 191 ASP A 207	STU A 401 (-3.9A) STU A 401 (-3.6A) STU A 401 (-4.7A) STU A 401 (-3.4A) STU A 401 (-3.2A) None STU A 401 (-4.5A) STU A 401 (-3.6A)	0.85A	2fumD-1nxkA: 21.6	2fumD-1nxkA: 24.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2HYY_A_STIA600_2 (PROTO-ONCOGENE TYROSINE-PROTEIN KINASE ABL1)	1nxk	MAP KINASE-ACTIVATED PROTEIN KINASE 2 (Homo sapiens)	5 / 6	LEU A 70 LYS A 93 VAL A 118 ILE A 136 ARG A 185	STU A 401 (-3.9A) STU A 401 ( 4.5A) None None None	0.90A	2hyyA-1nxkA: 19.1	2hyyA-1nxkA: 20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2HYY_B_STIB600_2 (PROTO-ONCOGENE TYROSINE-PROTEIN KINASE ABL1)	1nxk	MAP KINASE-ACTIVATED PROTEIN KINASE 2 (Homo sapiens)	4 / 6	LEU A 70 LYS A 93 VAL A 118 ILE A 136	STU A 401 (-3.9A) STU A 401 ( 4.5A) None None	0.50A	2hyyB-1nxkA: 19.3	2hyyB-1nxkA: 20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2QE6_A_SAMA400_0 (UNCHARACTERIZED PROTEIN TFU_2867)	1nxk	MAP KINASE-ACTIVATED PROTEIN KINASE 2 (Homo sapiens)	5 / 12	ILE A 136 GLY A 76 ASP A 97 ARG A 102 GLY A 209	None	0.83A	2qe6A-1nxkA: undetectable	2qe6A-1nxkA: 22.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2ZLC_A_VDXA500_1 (VITAMIN D3 RECEPTOR)	1nxk	MAP KINASE-ACTIVATED PROTEIN KINASE 2 (Homo sapiens)	5 / 12	TYR A 176 VAL A 118 VAL A 123 LEU A 95 LEU A 92	None	1.19A	2zlcA-1nxkA: 0.0	2zlcA-1nxkA: 20.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3CJT_C_SAMC302_0 (RIBOSOMAL PROTEIN L11 METHYLTRANSFERASE)	1nxk	MAP KINASE-ACTIVATED PROTEIN KINASE 2 (Homo sapiens)	5 / 12	GLY A 171 LEU A 205 ILE A 325 LEU A 249 LEU A 305	None	1.01A	3cjtC-1nxkA: undetectable	3cjtC-1nxkA: 21.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3CS9_A_NILA600_1 (PROTO-ONCOGENE TYROSINE-PROTEIN KINASE ABL1)	1nxk	MAP KINASE-ACTIVATED PROTEIN KINASE 2 (Homo sapiens)	5 / 10	LEU A 70 VAL A 78 LYS A 93 VAL A 118 ILE A 136	STU A 401 (-3.9A) STU A 401 (-4.7A) STU A 401 ( 4.5A) None None	0.52A	3cs9A-1nxkA: 19.3	3cs9A-1nxkA: 21.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3CS9_B_NILB600_2 (PROTO-ONCOGENE TYROSINE-PROTEIN KINASE ABL1)	1nxk	MAP KINASE-ACTIVATED PROTEIN KINASE 2 (Homo sapiens)	5 / 9	LEU A 70 VAL A 78 LYS A 93 ILE A 136 LEU A 193	STU A 401 (-3.9A) STU A 401 (-4.7A) STU A 401 ( 4.5A) None STU A 401 (-4.7A)	0.71A	3cs9B-1nxkA: 19.8	3cs9B-1nxkA: 21.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3CS9_B_NILB600_2 (PROTO-ONCOGENE TYROSINE-PROTEIN KINASE ABL1)	1nxk	MAP KINASE-ACTIVATED PROTEIN KINASE 2 (Homo sapiens)	6 / 9	LEU A 70 VAL A 78 LYS A 93 VAL A 118 ILE A 136 LEU A 141	STU A 401 (-3.9A) STU A 401 (-4.7A) STU A 401 ( 4.5A) None None STU A 401 (-3.9A)	1.18A	3cs9B-1nxkA: 19.8	3cs9B-1nxkA: 21.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3CS9_C_NILC600_2 (PROTO-ONCOGENE TYROSINE-PROTEIN KINASE ABL1)	1nxk	MAP KINASE-ACTIVATED PROTEIN KINASE 2 (Homo sapiens)	5 / 9	LEU A 70 VAL A 78 LYS A 93 VAL A 118 ILE A 136	STU A 401 (-3.9A) STU A 401 (-4.7A) STU A 401 ( 4.5A) None None	0.55A	3cs9C-1nxkA: 19.6	3cs9C-1nxkA: 21.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3CS9_D_NILD600_2 (PROTO-ONCOGENE TYROSINE-PROTEIN KINASE ABL1)	1nxk	MAP KINASE-ACTIVATED PROTEIN KINASE 2 (Homo sapiens)	4 / 6	LEU A 70 VAL A 78 LYS A 93 LEU A 193	STU A 401 (-3.9A) STU A 401 (-4.7A) STU A 401 ( 4.5A) STU A 401 (-4.7A)	0.71A	3cs9D-1nxkA: 18.1	3cs9D-1nxkA: 21.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3EYG_A_MI1A1_1 (TYROSINE-PROTEIN KINASE)	1nxk	MAP KINASE-ACTIVATED PROTEIN KINASE 2 (Homo sapiens)	9 / 12	LEU A 70 GLY A 71 GLY A 76 VAL A 78 ALA A 91 LYS A 93 MET A 138 ASN A 191 ASP A 207	STU A 401 (-3.9A) STU A 401 (-3.6A) None STU A 401 (-4.7A) STU A 401 (-3.4A) STU A 401 ( 4.5A) STU A 401 (-3.2A) STU A 401 (-4.5A) STU A 401 (-3.6A)	0.62A	3eygA-1nxkA: 21.6	3eygA-1nxkA: 25.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3FUP_A_MI1A1_1 (TYROSINE-PROTEIN KINASE JAK2)	1nxk	MAP KINASE-ACTIVATED PROTEIN KINASE 2 (Homo sapiens)	8 / 12	LEU A 70 GLY A 71 GLY A 76 VAL A 78 ALA A 91 LYS A 93 MET A 138 ASP A 207	STU A 401 (-3.9A) STU A 401 (-3.6A) None STU A 401 (-4.7A) STU A 401 (-3.4A) STU A 401 ( 4.5A) STU A 401 (-3.2A) STU A 401 (-3.6A)	0.50A	3fupA-1nxkA: 21.8	3fupA-1nxkA: 24.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3FUP_B_MI1B1_1 (TYROSINE-PROTEIN KINASE JAK2)	1nxk	MAP KINASE-ACTIVATED PROTEIN KINASE 2 (Homo sapiens)	9 / 12	LEU A 70 GLY A 71 VAL A 78 ALA A 91 LYS A 93 VAL A 118 MET A 138 LEU A 141 ASP A 207	STU A 401 (-3.9A) STU A 401 (-3.6A) STU A 401 (-4.7A) STU A 401 (-3.4A) STU A 401 ( 4.5A) None STU A 401 (-3.2A) STU A 401 (-3.9A) STU A 401 (-3.6A)	0.58A	3fupB-1nxkA: 21.6	3fupB-1nxkA: 24.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3HCP_B_CHDB4_0 (FERROCHELATASE, MITOCHONDRIAL)	1nxk	MAP KINASE-ACTIVATED PROTEIN KINASE 2 (Homo sapiens)	3 / 3	GLY A 282 PRO A 262 LEU A 306	None	0.61A	3hcpB-1nxkA: undetectable	3hcpB-1nxkA: 20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3K5V_A_STIA2_2 (TYROSINE-PROTEIN KINASE ABL1)	1nxk	MAP KINASE-ACTIVATED PROTEIN KINASE 2 (Homo sapiens)	4 / 6	LEU A 70 LYS A 93 VAL A 118 ILE A 136	STU A 401 (-3.9A) STU A 401 ( 4.5A) None None	0.48A	3k5vA-1nxkA: 19.2	3k5vA-1nxkA: 21.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3K5V_B_STIB2_2 (TYROSINE-PROTEIN KINASE ABL1)	1nxk	MAP KINASE-ACTIVATED PROTEIN KINASE 2 (Homo sapiens)	4 / 6	LEU A 70 LYS A 93 VAL A 118 ILE A 136	STU A 401 (-3.9A) STU A 401 ( 4.5A) None None	0.56A	3k5vB-1nxkA: 18.5	3k5vB-1nxkA: 21.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3LXK_A_MI1A1125_1 (TYROSINE-PROTEIN KINASE JAK3)	1nxk	MAP KINASE-ACTIVATED PROTEIN KINASE 2 (Homo sapiens)	8 / 12	LEU A 70 GLY A 71 VAL A 78 ALA A 91 LYS A 93 VAL A 118 MET A 138 ASP A 207	STU A 401 (-3.9A) STU A 401 (-3.6A) STU A 401 (-4.7A) STU A 401 (-3.4A) STU A 401 ( 4.5A) None STU A 401 (-3.2A) STU A 401 (-3.6A)	0.51A	3lxkA-1nxkA: 21.8	3lxkA-1nxkA: 25.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3MS9_A_STIA1_2 (TYROSINE-PROTEIN KINASE ABL1)	1nxk	MAP KINASE-ACTIVATED PROTEIN KINASE 2 (Homo sapiens)	4 / 6	LYS A 93 VAL A 118 ILE A 136 ARG A 185	STU A 401 ( 4.5A) None None None	0.96A	3ms9A-1nxkA: 19.3	3ms9A-1nxkA: 21.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3MS9_B_STIB1_2 (TYROSINE-PROTEIN KINASE ABL1)	1nxk	MAP KINASE-ACTIVATED PROTEIN KINASE 2 (Homo sapiens)	4 / 7	LYS A 93 VAL A 118 ILE A 136 ARG A 185	STU A 401 ( 4.5A) None None None	1.01A	3ms9B-1nxkA: 19.0	3ms9B-1nxkA: 21.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3MSS_A_STIA1_2 (TYROSINE-PROTEIN KINASE ABL1)	1nxk	MAP KINASE-ACTIVATED PROTEIN KINASE 2 (Homo sapiens)	4 / 6	LYS A 93 VAL A 118 ILE A 136 ARG A 185	STU A 401 ( 4.5A) None None None	0.97A	3mssA-1nxkA: 19.4	3mssA-1nxkA: 21.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3MSS_C_STIC1_2 (TYROSINE-PROTEIN KINASE ABL1)	1nxk	MAP KINASE-ACTIVATED PROTEIN KINASE 2 (Homo sapiens)	4 / 6	LYS A 93 VAL A 118 ILE A 136 ARG A 185	STU A 401 ( 4.5A) None None None	0.97A	3mssC-1nxkA: 19.3	3mssC-1nxkA: 21.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3MSS_D_STID1_2 (TYROSINE-PROTEIN KINASE ABL1)	1nxk	MAP KINASE-ACTIVATED PROTEIN KINASE 2 (Homo sapiens)	4 / 6	VAL A 78 LYS A 93 VAL A 118 ILE A 136	STU A 401 (-4.7A) STU A 401 ( 4.5A) None None	0.50A	3mssD-1nxkA: 19.3	3mssD-1nxkA: 21.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3PYY_A_STIA3_2 (V-ABL ABELSON MURINE LEUKEMIA VIRAL ONCOGENE HOMOLOG 1 ISOFORM B VARIANT)	1nxk	MAP KINASE-ACTIVATED PROTEIN KINASE 2 (Homo sapiens)	4 / 6	LYS A 93 VAL A 118 ILE A 136 ARG A 185	STU A 401 ( 4.5A) None None None	1.08A	3pyyA-1nxkA: 19.4	3pyyA-1nxkA: 22.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3UQB_A_FK5A114_1 (UBIQUITIN-LIKE PROTEIN SMT3, PEPTIDYL-PROLYL CIS-TRANS ISOMERASE)	1nxk	MAP KINASE-ACTIVATED PROTEIN KINASE 2 (Homo sapiens)	4 / 8	VAL A 251 ILE A 252 ILE A 166 PHE A 147	None	0.86A	3uqbA-1nxkA: undetectable	3uqbA-1nxkA: 19.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4L9I_A_8PRA601_1 (RHODOPSIN KINASE)	1nxk	MAP KINASE-ACTIVATED PROTEIN KINASE 2 (Homo sapiens)	4 / 7	VAL A 78 ALA A 91 LEU A 95 MET A 138	STU A 401 (-4.7A) STU A 401 (-3.4A) None STU A 401 (-3.2A)	0.51A	4l9iA-1nxkA: 7.1	4l9iA-1nxkA: 22.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4L9I_A_8PRA601_1 (RHODOPSIN KINASE)	1nxk	MAP KINASE-ACTIVATED PROTEIN KINASE 2 (Homo sapiens)	4 / 7	VAL A 78 ALA A 91 MET A 138 LEU A 193	STU A 401 (-4.7A) STU A 401 (-3.4A) STU A 401 (-3.2A) STU A 401 (-4.7A)	0.77A	4l9iA-1nxkA: 7.1	4l9iA-1nxkA: 22.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4O0W_A_ADNA501_1 (AURORA KINASE A)	1nxk	MAP KINASE-ACTIVATED PROTEIN KINASE 2 (Homo sapiens)	4 / 6	LEU A 70 GLY A 71 VAL A 78 ALA A 91	STU A 401 (-3.9A) STU A 401 (-3.6A) STU A 401 (-4.7A) STU A 401 (-3.4A)	0.22A	4o0wA-1nxkA: 22.8	4o0wA-1nxkA: 27.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4O8F_B_BRLB501_1 (PEROXISOME PROLIFERATOR-ACTIVAT ED RECEPTOR GAMMA)	1nxk	MAP KINASE-ACTIVATED PROTEIN KINASE 2 (Homo sapiens)	5 / 12	SER A 169 VAL A 331 PHE A 158 LEU A 203 TYR A 194	None	0.98A	4o8fB-1nxkA: 0.0	4o8fB-1nxkA: 20.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4OGR_A_ADNA401_1 (CYCLIN-DEPENDENT KINASE 9)	1nxk	MAP KINASE-ACTIVATED PROTEIN KINASE 2 (Homo sapiens)	5 / 8	GLY A 73 VAL A 78 ALA A 91 ASN A 191 ASP A 207	STU A 401 (-3.6A) STU A 401 (-4.7A) STU A 401 (-3.4A) STU A 401 (-4.5A) STU A 401 (-3.6A)	0.44A	4ogrA-1nxkA: 22.2	4ogrA-1nxkA: 23.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4OGR_E_ADNE401_1 (CYCLIN-DEPENDENT KINASE 9)	1nxk	MAP KINASE-ACTIVATED PROTEIN KINASE 2 (Homo sapiens)	5 / 7	GLY A 71 ALA A 91 ASN A 191 LEU A 193 ASP A 207	STU A 401 (-3.6A) STU A 401 (-3.4A) STU A 401 (-4.5A) STU A 401 (-4.7A) STU A 401 (-3.6A)	0.97A	4ogrE-1nxkA: 21.4	4ogrE-1nxkA: 23.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4OGR_I_ADNI401_1 (CYCLIN-DEPENDENT KINASE 9)	1nxk	MAP KINASE-ACTIVATED PROTEIN KINASE 2 (Homo sapiens)	6 / 9	GLY A 73 VAL A 78 ALA A 91 ASN A 191 LEU A 193 ASP A 207	STU A 401 (-3.6A) STU A 401 (-4.7A) STU A 401 (-3.4A) STU A 401 (-4.5A) STU A 401 (-4.7A) STU A 401 (-3.6A)	0.83A	4ogrI-1nxkA: 22.3	4ogrI-1nxkA: 23.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4P6X_G_HCYG900_1 (GLUCOCORTICOID RECEPTOR)	1nxk	MAP KINASE-ACTIVATED PROTEIN KINASE 2 (Homo sapiens)	5 / 12	TRP A 324 LEU A 249 THR A 338 ILE A 150 PHE A 158	None	1.43A	4p6xG-1nxkA: undetectable	4p6xG-1nxkA: 20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4POO_A_SAMA301_0 (PUTATIVE RNA METHYLASE)	1nxk	MAP KINASE-ACTIVATED PROTEIN KINASE 2 (Homo sapiens)	5 / 12	GLY A 73 ASP A 186 ILE A 136 HIS A 108 ASN A 191	STU A 401 (-3.6A) None None None STU A 401 (-4.5A)	1.32A	4pooA-1nxkA: undetectable	4pooA-1nxkA: 20.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4QMZ_A_B49A401_1 (SERINE/THREONINE-PRO TEIN KINASE 24)	1nxk	MAP KINASE-ACTIVATED PROTEIN KINASE 2 (Homo sapiens)	6 / 12	GLY A 71 VAL A 78 ALA A 91 MET A 138 LEU A 141 LEU A 193	STU A 401 (-3.6A) STU A 401 (-4.7A) STU A 401 (-3.4A) STU A 401 (-3.2A) STU A 401 (-3.9A) STU A 401 (-4.7A)	0.90A	4qmzA-1nxkA: 24.0	4qmzA-1nxkA: 27.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4QRC_A_0LIA802_2 (FIBROBLAST GROWTH FACTOR RECEPTOR 4)	1nxk	MAP KINASE-ACTIVATED PROTEIN KINASE 2 (Homo sapiens)	4 / 8	LEU A 70 VAL A 78 LYS A 93 LEU A 193	STU A 401 (-3.9A) STU A 401 (-4.7A) STU A 401 ( 4.5A) STU A 401 (-4.7A)	0.61A	4qrcA-1nxkA: 19.7	4qrcA-1nxkA: 25.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4WBO_C_ANWC601_0 (RHODOPSIN KINASE)	1nxk	MAP KINASE-ACTIVATED PROTEIN KINASE 2 (Homo sapiens)	4 / 6	LEU A 70 ALA A 91 MET A 138 LEU A 193	STU A 401 (-3.9A) STU A 401 (-3.4A) STU A 401 (-3.2A) STU A 401 (-4.7A)	0.69A	4wboC-1nxkA: 20.1	4wboC-1nxkA: 21.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5J5X_B_AZ1B2_1 (CAMP-DEPENDENT PROTEIN KINASE CATALYTIC SUBUNIT ALPHA 47P-AZ1-DAL-DAR-DAR- DAR-DAR)	1nxk	MAP KINASE-ACTIVATED PROTEIN KINASE 2 (Homo sapiens)	4 / 7	GLY A 71 VAL A 78 LYS A 93 ASP A 207	STU A 401 (-3.6A) STU A 401 (-4.7A) STU A 401 ( 4.5A) STU A 401 (-3.6A)	0.42A	5j5xA-1nxkA: 21.9	5j5xA-1nxkA: 28.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5N3H_A_NCAA401_0 (CAMP-DEPENDENT PROTEIN KINASE CATALYTIC SUBUNIT ALPHA)	1nxk	MAP KINASE-ACTIVATED PROTEIN KINASE 2 (Homo sapiens)	6 / 10	LEU A 70 VAL A 78 ALA A 91 MET A 138 LEU A 193 THR A 206	STU A 401 (-3.9A) STU A 401 (-4.7A) STU A 401 (-3.4A) STU A 401 (-3.2A) STU A 401 (-4.7A) STU A 401 (-3.2A)	0.80A	5n3hA-1nxkA: 22.0	5n3hA-1nxkA: 27.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5N3H_A_NCAA401_0 (CAMP-DEPENDENT PROTEIN KINASE CATALYTIC SUBUNIT ALPHA)	1nxk	MAP KINASE-ACTIVATED PROTEIN KINASE 2 (Homo sapiens)	6 / 10	LEU A 70 VAL A 78 ALA A 91 VAL A 118 MET A 138 THR A 206	STU A 401 (-3.9A) STU A 401 (-4.7A) STU A 401 (-3.4A) None STU A 401 (-3.2A) STU A 401 (-3.2A)	0.66A	5n3hA-1nxkA: 22.0	5n3hA-1nxkA: 27.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5NWW_A_ACAA18_1 (SCRFP-TAG,GP41)	1nxk	MAP KINASE-ACTIVATED PROTEIN KINASE 2 (Homo sapiens)	5 / 12	GLY A 71 LYS A 77 LEU A 192 GLU A 145 LEU A 193	STU A 401 (-3.6A) None None None STU A 401 (-4.7A)	1.07A	5nwwA-1nxkA: undetectable	5nwwA-1nxkA: 6.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5VC3_A_DB8A601_2 (WEE1-LIKE PROTEIN KINASE)	1nxk	MAP KINASE-ACTIVATED PROTEIN KINASE 2 (Homo sapiens)	4 / 4	VAL A 78 LYS A 93 VAL A 118 ASN A 191	STU A 401 (-4.7A) STU A 401 ( 4.5A) None STU A 401 (-4.5A)	0.95A	5vc3A-1nxkA: 21.0	5vc3A-1nxkA: 23.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5W5V_A_ANWA701_0 (SERINE/THREONINE-PRO TEIN KINASE TBK1)	1nxk	MAP KINASE-ACTIVATED PROTEIN KINASE 2 (Homo sapiens)	5 / 9	LEU A 70 ALA A 91 VAL A 118 MET A 138 THR A 206	STU A 401 (-3.9A) STU A 401 (-3.4A) None STU A 401 (-3.2A) STU A 401 (-3.2A)	1.07A	5w5vA-1nxkA: 2.8	5w5vA-1nxkA: 21.12

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1E06_B_IPBB600_0","ODORANT-BINDING PROTEIN","1nxk","MAP KINASE-ACTIVATED PROTEIN KINASE 2","Homo sapiens",4,"ILE A 170;MET A 253;VAL A 331;GLY A 171","None","1.31A","1e06B-1nxkA:0.4","1e06B-1nxkA:19.12"],["1FMO_E_ADNE351_1","CAMP-DEPENDENT PROTEIN KINASE","1nxk","MAP KINASE-ACTIVATED PROTEIN KINASE 2","Homo sapiens",8,"LEU A  70;GLY A  71;VAL A  78;ALA A  91;ASN A 191;LEU A 193;THR A 206;ASP A 207","STU A 401 (-3.9A);STU A 401 (-3.6A);STU A 401 (-4.7A);STU A 401 (-3.4A);STU A 401 (-4.5A);STU A 401 (-4.7A);STU A 401 (-3.2A);STU A 401 (-3.6A)","0.72A","1fmoE-1nxkA:22.4","1fmoE-1nxkA:27.88"],["1FMO_E_ADNE351_1","CAMP-DEPENDENT PROTEIN KINASE","1nxk","MAP KINASE-ACTIVATED PROTEIN KINASE 2","Homo sapiens",8,"LEU A  70;GLY A  71;VAL A  78;ALA A  91;VAL A 118;ASN A 191;THR A 206;ASP A 207","STU A 401 (-3.9A);STU A 401 (-3.6A);STU A 401 (-4.7A);STU A 401 (-3.4A);None;STU A 401 (-4.5A);STU A 401 (-3.2A);STU A 401 (-3.6A)","0.64A","1fmoE-1nxkA:22.4","1fmoE-1nxkA:27.88"],["1MUO_A_ADNA1_1","AURORA-RELATED KINASE 1","1nxk","MAP KINASE-ACTIVATED PROTEIN KINASE 2","Homo sapiens",5,"LEU A  70;GLY A  71;VAL A  78;ALA A  91;LEU A 193","STU A 401 (-3.9A);STU A 401 (-3.6A);STU A 401 (-4.7A);STU A 401 (-3.4A);STU A 401 (-4.7A)","0.51A","1muoA-1nxkA:7.8","1muoA-1nxkA:28.33"],["1RA8_A_FOLA161_1","DIHYDROFOLATE REDUCTASE","1nxk","MAP KINASE-ACTIVATED PROTEIN KINASE 2","Homo sapiens",3,"ASP A  97;LYS A 100;ARG A 103","None","1.18A","1ra8A-1nxkA:undetectable","1ra8A-1nxkA:17.53"],["1RA8_A_FOLA161_1","DIHYDROFOLATE REDUCTASE","1nxk","MAP KINASE-ACTIVATED PROTEIN KINASE 2","Homo sapiens",3,"ASP A 245;LYS A 212;ARG A 103","None","1.19A","1ra8A-1nxkA:undetectable","1ra8A-1nxkA:17.53"],["1S8F_A_BEZA1501_0","RAS-RELATED PROTEIN RAB-9A","1nxk","MAP KINASE-ACTIVATED PROTEIN KINASE 2","Homo sapiens",4,"ILE A 302;TRP A 291;LEU A 306;PRO A 262","None","1.35A","1s8fA-1nxkA:0.1;1s8fB-1nxkA:0.0","1s8fA-1nxkA:19.90;1s8fB-1nxkA:19.90"],["2FUM_A_MIXA539_1","PROBABLE SERINE\/THREONINE-PROTEIN KINASE PKNB","1nxk","MAP KINASE-ACTIVATED PROTEIN KINASE 2","Homo sapiens",8,"LEU A  70;GLY A  71;VAL A  78;ALA A  91;ASP A 186;LYS A 188;ASN A 191;ASP A 207","STU A 401 (-3.9A);STU A 401 (-3.6A);STU A 401 (-4.7A);STU A 401 (-3.4A);None;None;STU A 401 (-4.5A);STU A 401 (-3.6A)","0.72A","2fumA-1nxkA:23.4","2fumA-1nxkA:24.52"],["2FUM_B_MIXB1539_1","PROBABLE SERINE\/THREONINE-PROTEIN KINASE PKNB","1nxk","MAP KINASE-ACTIVATED PROTEIN KINASE 2","Homo sapiens",8,"LEU A  70;GLY A  71;VAL A  78;ALA A  91;MET A 138;LYS A 188;ASN A 191;ASP A 207","STU A 401 (-3.9A);STU A 401 (-3.6A);STU A 401 (-4.7A);STU A 401 (-3.4A);STU A 401 (-3.2A);None;STU A 401 (-4.5A);STU A 401 (-3.6A)","0.76A","2fumB-1nxkA:23.4","2fumB-1nxkA:24.52"],["2FUM_C_MIXC2539_1","PROBABLE SERINE\/THREONINE-PROTEIN KINASE PKNB","1nxk","MAP KINASE-ACTIVATED PROTEIN KINASE 2","Homo sapiens",6,"LEU A  70;GLY A  71;VAL A  78;ALA A  91;MET A 138;ASN A 191","STU A 401 (-3.9A);STU A 401 (-3.6A);STU A 401 (-4.7A);STU A 401 (-3.4A);STU A 401 (-3.2A);STU A 401 (-4.5A)","0.54A","2fumC-1nxkA:21.6","2fumC-1nxkA:24.52"],["2FUM_D_MIXD3539_1","PROBABLE SERINE\/THREONINE-PROTEIN KINASE PKNB","1nxk","MAP KINASE-ACTIVATED PROTEIN KINASE 2","Homo sapiens",8,"LEU A  70;GLY A  71;VAL A  78;ALA A  91;MET A 138;LYS A 188;ASN A 191;ASP A 207","STU A 401 (-3.9A);STU A 401 (-3.6A);STU A 401 (-4.7A);STU A 401 (-3.4A);STU A 401 (-3.2A);None;STU A 401 (-4.5A);STU A 401 (-3.6A)","0.85A","2fumD-1nxkA:21.6","2fumD-1nxkA:24.52"],["2HYY_A_STIA600_2","PROTO-ONCOGENE TYROSINE-PROTEIN KINASE ABL1","1nxk","MAP KINASE-ACTIVATED PROTEIN KINASE 2","Homo sapiens",5,"LEU A  70;LYS A  93;VAL A 118;ILE A 136;ARG A 185","STU A 401 (-3.9A);STU A 401 ( 4.5A);None;None;None","0.90A","2hyyA-1nxkA:19.1","2hyyA-1nxkA:20.73"],["2HYY_B_STIB600_2","PROTO-ONCOGENE TYROSINE-PROTEIN KINASE ABL1","1nxk","MAP KINASE-ACTIVATED PROTEIN KINASE 2","Homo sapiens",4,"LEU A  70;LYS A  93;VAL A 118;ILE A 136","STU A 401 (-3.9A);STU A 401 ( 4.5A);None;None","0.50A","2hyyB-1nxkA:19.3","2hyyB-1nxkA:20.73"],["2QE6_A_SAMA400_0","UNCHARACTERIZED PROTEIN TFU_2867","1nxk","MAP KINASE-ACTIVATED PROTEIN KINASE 2","Homo sapiens",5,"ILE A 136;GLY A  76;ASP A  97;ARG A 102;GLY A 209","None","0.83A","2qe6A-1nxkA:undetectable","2qe6A-1nxkA:22.61"],["2ZLC_A_VDXA500_1","VITAMIN D3 RECEPTOR","1nxk","MAP KINASE-ACTIVATED PROTEIN KINASE 2","Homo sapiens",5,"TYR A 176;VAL A 118;VAL A 123;LEU A  95;LEU A  92","None","1.19A","2zlcA-1nxkA:0.0","2zlcA-1nxkA:20.62"],["3CJT_C_SAMC302_0","RIBOSOMAL PROTEIN L11 METHYLTRANSFERASE","1nxk","MAP KINASE-ACTIVATED PROTEIN KINASE 2","Homo sapiens",5,"GLY A 171;LEU A 205;ILE A 325;LEU A 249;LEU A 305","None","1.01A","3cjtC-1nxkA:undetectable","3cjtC-1nxkA:21.34"],["3CS9_A_NILA600_1","PROTO-ONCOGENE TYROSINE-PROTEIN KINASE ABL1","1nxk","MAP KINASE-ACTIVATED PROTEIN KINASE 2","Homo sapiens",5,"LEU A  70;VAL A  78;LYS A  93;VAL A 118;ILE A 136","STU A 401 (-3.9A);STU A 401 (-4.7A);STU A 401 ( 4.5A);None;None","0.52A","3cs9A-1nxkA:19.3","3cs9A-1nxkA:21.53"],["3CS9_B_NILB600_2","PROTO-ONCOGENE TYROSINE-PROTEIN KINASE ABL1","1nxk","MAP KINASE-ACTIVATED PROTEIN KINASE 2","Homo sapiens",5,"LEU A  70;VAL A  78;LYS A  93;ILE A 136;LEU A 193","STU A 401 (-3.9A);STU A 401 (-4.7A);STU A 401 ( 4.5A);None;STU A 401 (-4.7A)","0.71A","3cs9B-1nxkA:19.8","3cs9B-1nxkA:21.53"],["3CS9_B_NILB600_2","PROTO-ONCOGENE TYROSINE-PROTEIN KINASE ABL1","1nxk","MAP KINASE-ACTIVATED PROTEIN KINASE 2","Homo sapiens",6,"LEU A  70;VAL A  78;LYS A  93;VAL A 118;ILE A 136;LEU A 141","STU A 401 (-3.9A);STU A 401 (-4.7A);STU A 401 ( 4.5A);None;None;STU A 401 (-3.9A)","1.18A","3cs9B-1nxkA:19.8","3cs9B-1nxkA:21.53"],["3CS9_C_NILC600_2","PROTO-ONCOGENE TYROSINE-PROTEIN KINASE ABL1","1nxk","MAP KINASE-ACTIVATED PROTEIN KINASE 2","Homo sapiens",5,"LEU A  70;VAL A  78;LYS A  93;VAL A 118;ILE A 136","STU A 401 (-3.9A);STU A 401 (-4.7A);STU A 401 ( 4.5A);None;None","0.55A","3cs9C-1nxkA:19.6","3cs9C-1nxkA:21.53"],["3CS9_D_NILD600_2","PROTO-ONCOGENE TYROSINE-PROTEIN KINASE ABL1","1nxk","MAP KINASE-ACTIVATED PROTEIN KINASE 2","Homo sapiens",4,"LEU A  70;VAL A  78;LYS A  93;LEU A 193","STU A 401 (-3.9A);STU A 401 (-4.7A);STU A 401 ( 4.5A);STU A 401 (-4.7A)","0.71A","3cs9D-1nxkA:18.1","3cs9D-1nxkA:21.53"],["3EYG_A_MI1A1_1","TYROSINE-PROTEIN KINASE","1nxk","MAP KINASE-ACTIVATED PROTEIN KINASE 2","Homo sapiens",9,"LEU A  70;GLY A  71;GLY A  76;VAL A  78;ALA A  91;LYS A  93;MET A 138;ASN A 191;ASP A 207","STU A 401 (-3.9A);STU A 401 (-3.6A);None;STU A 401 (-4.7A);STU A 401 (-3.4A);STU A 401 ( 4.5A);STU A 401 (-3.2A);STU A 401 (-4.5A);STU A 401 (-3.6A)","0.62A","3eygA-1nxkA:21.6","3eygA-1nxkA:25.32"],["3FUP_A_MI1A1_1","TYROSINE-PROTEIN KINASE JAK2","1nxk","MAP KINASE-ACTIVATED PROTEIN KINASE 2","Homo sapiens",8,"LEU A  70;GLY A  71;GLY A  76;VAL A  78;ALA A  91;LYS A  93;MET A 138;ASP A 207","STU A 401 (-3.9A);STU A 401 (-3.6A);None;STU A 401 (-4.7A);STU A 401 (-3.4A);STU A 401 ( 4.5A);STU A 401 (-3.2A);STU A 401 (-3.6A)","0.50A","3fupA-1nxkA:21.8","3fupA-1nxkA:24.23"],["3FUP_B_MI1B1_1","TYROSINE-PROTEIN KINASE JAK2","1nxk","MAP KINASE-ACTIVATED PROTEIN KINASE 2","Homo sapiens",9,"LEU A  70;GLY A  71;VAL A  78;ALA A  91;LYS A  93;VAL A 118;MET A 138;LEU A 141;ASP A 207","STU A 401 (-3.9A);STU A 401 (-3.6A);STU A 401 (-4.7A);STU A 401 (-3.4A);STU A 401 ( 4.5A);None;STU A 401 (-3.2A);STU A 401 (-3.9A);STU A 401 (-3.6A)","0.58A","3fupB-1nxkA:21.6","3fupB-1nxkA:24.23"],["3HCP_B_CHDB4_0","FERROCHELATASE, MITOCHONDRIAL","1nxk","MAP KINASE-ACTIVATED PROTEIN KINASE 2","Homo sapiens",3,"GLY A 282;PRO A 262;LEU A 306","None","0.61A","3hcpB-1nxkA:undetectable","3hcpB-1nxkA:20.99"],["3K5V_A_STIA2_2","TYROSINE-PROTEIN KINASE ABL1","1nxk","MAP KINASE-ACTIVATED PROTEIN KINASE 2","Homo sapiens",4,"LEU A  70;LYS A  93;VAL A 118;ILE A 136","STU A 401 (-3.9A);STU A 401 ( 4.5A);None;None","0.48A","3k5vA-1nxkA:19.2","3k5vA-1nxkA:21.95"],["3K5V_B_STIB2_2","TYROSINE-PROTEIN KINASE ABL1","1nxk","MAP KINASE-ACTIVATED PROTEIN KINASE 2","Homo sapiens",4,"LEU A  70;LYS A  93;VAL A 118;ILE A 136","STU A 401 (-3.9A);STU A 401 ( 4.5A);None;None","0.56A","3k5vB-1nxkA:18.5","3k5vB-1nxkA:21.95"],["3LXK_A_MI1A1125_1","TYROSINE-PROTEIN KINASE JAK3","1nxk","MAP KINASE-ACTIVATED PROTEIN KINASE 2","Homo sapiens",8,"LEU A  70;GLY A  71;VAL A  78;ALA A  91;LYS A  93;VAL A 118;MET A 138;ASP A 207","STU A 401 (-3.9A);STU A 401 (-3.6A);STU A 401 (-4.7A);STU A 401 (-3.4A);STU A 401 ( 4.5A);None;STU A 401 (-3.2A);STU A 401 (-3.6A)","0.51A","3lxkA-1nxkA:21.8","3lxkA-1nxkA:25.71"],["3MS9_A_STIA1_2","TYROSINE-PROTEIN KINASE ABL1","1nxk","MAP KINASE-ACTIVATED PROTEIN KINASE 2","Homo sapiens",4,"LYS A  93;VAL A 118;ILE A 136;ARG A 185","STU A 401 ( 4.5A);None;None;None","0.96A","3ms9A-1nxkA:19.3","3ms9A-1nxkA:21.95"],["3MS9_B_STIB1_2","TYROSINE-PROTEIN KINASE ABL1","1nxk","MAP KINASE-ACTIVATED PROTEIN KINASE 2","Homo sapiens",4,"LYS A  93;VAL A 118;ILE A 136;ARG A 185","STU A 401 ( 4.5A);None;None;None","1.01A","3ms9B-1nxkA:19.0","3ms9B-1nxkA:21.95"],["3MSS_A_STIA1_2","TYROSINE-PROTEIN KINASE ABL1","1nxk","MAP KINASE-ACTIVATED PROTEIN KINASE 2","Homo sapiens",4,"LYS A  93;VAL A 118;ILE A 136;ARG A 185","STU A 401 ( 4.5A);None;None;None","0.97A","3mssA-1nxkA:19.4","3mssA-1nxkA:21.95"],["3MSS_C_STIC1_2","TYROSINE-PROTEIN KINASE ABL1","1nxk","MAP KINASE-ACTIVATED PROTEIN KINASE 2","Homo sapiens",4,"LYS A  93;VAL A 118;ILE A 136;ARG A 185","STU A 401 ( 4.5A);None;None;None","0.97A","3mssC-1nxkA:19.3","3mssC-1nxkA:21.95"],["3MSS_D_STID1_2","TYROSINE-PROTEIN KINASE ABL1","1nxk","MAP KINASE-ACTIVATED PROTEIN KINASE 2","Homo sapiens",4,"VAL A  78;LYS A  93;VAL A 118;ILE A 136","STU A 401 (-4.7A);STU A 401 ( 4.5A);None;None","0.50A","3mssD-1nxkA:19.3","3mssD-1nxkA:21.95"],["3PYY_A_STIA3_2","V-ABL ABELSON MURINE LEUKEMIA VIRAL ONCOGENE HOMOLOG 1 ISOFORM B VARIANT","1nxk","MAP KINASE-ACTIVATED PROTEIN KINASE 2","Homo sapiens",4,"LYS A  93;VAL A 118;ILE A 136;ARG A 185","STU A 401 ( 4.5A);None;None;None","1.08A","3pyyA-1nxkA:19.4","3pyyA-1nxkA:22.19"],["3UQB_A_FK5A114_1","UBIQUITIN-LIKE PROTEIN SMT3, PEPTIDYL-PROLYL CIS-TRANS ISOMERASE","1nxk","MAP KINASE-ACTIVATED PROTEIN KINASE 2","Homo sapiens",4,"VAL A 251;ILE A 252;ILE A 166;PHE A 147","None","0.86A","3uqbA-1nxkA:undetectable","3uqbA-1nxkA:19.55"],["4L9I_A_8PRA601_1","RHODOPSIN KINASE","1nxk","MAP KINASE-ACTIVATED PROTEIN KINASE 2","Homo sapiens",4,"VAL A  78;ALA A  91;LEU A  95;MET A 138","STU A 401 (-4.7A);STU A 401 (-3.4A);None;STU A 401 (-3.2A)","0.51A","4l9iA-1nxkA:7.1","4l9iA-1nxkA:22.69"],["4L9I_A_8PRA601_1","RHODOPSIN KINASE","1nxk","MAP KINASE-ACTIVATED PROTEIN KINASE 2","Homo sapiens",4,"VAL A  78;ALA A  91;MET A 138;LEU A 193","STU A 401 (-4.7A);STU A 401 (-3.4A);STU A 401 (-3.2A);STU A 401 (-4.7A)","0.77A","4l9iA-1nxkA:7.1","4l9iA-1nxkA:22.69"],["4O0W_A_ADNA501_1","AURORA KINASE A","1nxk","MAP KINASE-ACTIVATED PROTEIN KINASE 2","Homo sapiens",4,"LEU A  70;GLY A  71;VAL A  78;ALA A  91","STU A 401 (-3.9A);STU A 401 (-3.6A);STU A 401 (-4.7A);STU A 401 (-3.4A)","0.22A","4o0wA-1nxkA:22.8","4o0wA-1nxkA:27.09"],["4O8F_B_BRLB501_1","PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR GAMMA","1nxk","MAP KINASE-ACTIVATED PROTEIN KINASE 2","Homo sapiens",5,"SER A 169;VAL A 331;PHE A 158;LEU A 203;TYR A 194","None","0.98A","4o8fB-1nxkA:0.0","4o8fB-1nxkA:20.55"],["4OGR_A_ADNA401_1","CYCLIN-DEPENDENT KINASE 9","1nxk","MAP KINASE-ACTIVATED PROTEIN KINASE 2","Homo sapiens",5,"GLY A  73;VAL A  78;ALA A  91;ASN A 191;ASP A 207","STU A 401 (-3.6A);STU A 401 (-4.7A);STU A 401 (-3.4A);STU A 401 (-4.5A);STU A 401 (-3.6A)","0.44A","4ogrA-1nxkA:22.2","4ogrA-1nxkA:23.33"],["4OGR_E_ADNE401_1","CYCLIN-DEPENDENT KINASE 9","1nxk","MAP KINASE-ACTIVATED PROTEIN KINASE 2","Homo sapiens",5,"GLY A  71;ALA A  91;ASN A 191;LEU A 193;ASP A 207","STU A 401 (-3.6A);STU A 401 (-3.4A);STU A 401 (-4.5A);STU A 401 (-4.7A);STU A 401 (-3.6A)","0.97A","4ogrE-1nxkA:21.4","4ogrE-1nxkA:23.33"],["4OGR_I_ADNI401_1","CYCLIN-DEPENDENT KINASE 9","1nxk","MAP KINASE-ACTIVATED PROTEIN KINASE 2","Homo sapiens",6,"GLY A  73;VAL A  78;ALA A  91;ASN A 191;LEU A 193;ASP A 207","STU A 401 (-3.6A);STU A 401 (-4.7A);STU A 401 (-3.4A);STU A 401 (-4.5A);STU A 401 (-4.7A);STU A 401 (-3.6A)","0.83A","4ogrI-1nxkA:22.3","4ogrI-1nxkA:23.33"],["4P6X_G_HCYG900_1","GLUCOCORTICOID RECEPTOR","1nxk","MAP KINASE-ACTIVATED PROTEIN KINASE 2","Homo sapiens",5,"TRP A 324;LEU A 249;THR A 338;ILE A 150;PHE A 158","None","1.43A","4p6xG-1nxkA:undetectable","4p6xG-1nxkA:20.63"],["4POO_A_SAMA301_0","PUTATIVE RNA METHYLASE","1nxk","MAP KINASE-ACTIVATED PROTEIN KINASE 2","Homo sapiens",5,"GLY A  73;ASP A 186;ILE A 136;HIS A 108;ASN A 191","STU A 401 (-3.6A);None;None;None;STU A 401 (-4.5A)","1.32A","4pooA-1nxkA:undetectable","4pooA-1nxkA:20.10"],["4QMZ_A_B49A401_1","SERINE\/THREONINE-PROTEIN KINASE 24","1nxk","MAP KINASE-ACTIVATED PROTEIN KINASE 2","Homo sapiens",6,"GLY A  71;VAL A  78;ALA A  91;MET A 138;LEU A 141;LEU A 193","STU A 401 (-3.6A);STU A 401 (-4.7A);STU A 401 (-3.4A);STU A 401 (-3.2A);STU A 401 (-3.9A);STU A 401 (-4.7A)","0.90A","4qmzA-1nxkA:24.0","4qmzA-1nxkA:27.43"],["4QRC_A_0LIA802_2","FIBROBLAST GROWTH FACTOR RECEPTOR 4","1nxk","MAP KINASE-ACTIVATED PROTEIN KINASE 2","Homo sapiens",4,"LEU A  70;VAL A  78;LYS A  93;LEU A 193","STU A 401 (-3.9A);STU A 401 (-4.7A);STU A 401 ( 4.5A);STU A 401 (-4.7A)","0.61A","4qrcA-1nxkA:19.7","4qrcA-1nxkA:25.23"],["4WBO_C_ANWC601_0","RHODOPSIN KINASE","1nxk","MAP KINASE-ACTIVATED PROTEIN KINASE 2","Homo sapiens",4,"LEU A  70;ALA A  91;MET A 138;LEU A 193","STU A 401 (-3.9A);STU A 401 (-3.4A);STU A 401 (-3.2A);STU A 401 (-4.7A)","0.69A","4wboC-1nxkA:20.1","4wboC-1nxkA:21.48"],["5J5X_B_AZ1B2_1","CAMP-DEPENDENT PROTEIN KINASE CATALYTIC SUBUNIT ALPHA;47P-AZ1-DAL-DAR-DAR-DAR-DAR","1nxk","MAP KINASE-ACTIVATED PROTEIN KINASE 2","Homo sapiens",4,"GLY A  71;VAL A  78;LYS A  93;ASP A 207","STU A 401 (-3.6A);STU A 401 (-4.7A);STU A 401 ( 4.5A);STU A 401 (-3.6A)","0.42A","5j5xA-1nxkA:21.9","5j5xA-1nxkA:28.30"],["5N3H_A_NCAA401_0","CAMP-DEPENDENT PROTEIN KINASE CATALYTIC SUBUNIT ALPHA","1nxk","MAP KINASE-ACTIVATED PROTEIN KINASE 2","Homo sapiens",6,"LEU A  70;VAL A  78;ALA A  91;MET A 138;LEU A 193;THR A 206","STU A 401 (-3.9A);STU A 401 (-4.7A);STU A 401 (-3.4A);STU A 401 (-3.2A);STU A 401 (-4.7A);STU A 401 (-3.2A)","0.80A","5n3hA-1nxkA:22.0","5n3hA-1nxkA:27.54"],["5N3H_A_NCAA401_0","CAMP-DEPENDENT PROTEIN KINASE CATALYTIC SUBUNIT ALPHA","1nxk","MAP KINASE-ACTIVATED PROTEIN KINASE 2","Homo sapiens",6,"LEU A  70;VAL A  78;ALA A  91;VAL A 118;MET A 138;THR A 206","STU A 401 (-3.9A);STU A 401 (-4.7A);STU A 401 (-3.4A);None;STU A 401 (-3.2A);STU A 401 (-3.2A)","0.66A","5n3hA-1nxkA:22.0","5n3hA-1nxkA:27.54"],["5NWW_A_ACAA18_1","SCRFP-TAG,GP41","1nxk","MAP KINASE-ACTIVATED PROTEIN KINASE 2","Homo sapiens",5,"GLY A  71;LYS A  77;LEU A 192;GLU A 145;LEU A 193","STU A 401 (-3.6A);None;None;None;STU A 401 (-4.7A)","1.07A","5nwwA-1nxkA:undetectable","5nwwA-1nxkA:6.36"],["5VC3_A_DB8A601_2","WEE1-LIKE PROTEIN KINASE","1nxk","MAP KINASE-ACTIVATED PROTEIN KINASE 2","Homo sapiens",4,"VAL A  78;LYS A  93;VAL A 118;ASN A 191","STU A 401 (-4.7A);STU A 401 ( 4.5A);None;STU A 401 (-4.5A)","0.95A","5vc3A-1nxkA:21.0","5vc3A-1nxkA:23.92"],["5W5V_A_ANWA701_0","SERINE\/THREONINE-PROTEIN KINASE TBK1","1nxk","MAP KINASE-ACTIVATED PROTEIN KINASE 2","Homo sapiens",5,"LEU A  70;ALA A  91;VAL A 118;MET A 138;THR A 206","STU A 401 (-3.9A);STU A 401 (-3.4A);None;STU A 401 (-3.2A);STU A 401 (-3.2A)","1.07A","5w5vA-1nxkA:2.8","5w5vA-1nxkA:21.12"]]