SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1ny1'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1T6Z_A_RBFA296_1
(RIBOFLAVIN
KINASE/FMN
ADENYLYLTRANSFERASE)		 1ny1 PROBABLE
POLYSACCHARIDE
DEACETYLASE PDAA
(Bacillus
subtilis) 		5 / 11 VAL A  99
VAL A 104
ASN A  74
GLU A  77
LEU A  85
 None
 1.26A 1t6zA-1ny1A:
undetectable		 1t6zA-1ny1A:
24.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2GJ5_A_VD3A164_1
(BETA-LACTOGLOBULIN)		 1ny1 PROBABLE
POLYSACCHARIDE
DEACETYLASE PDAA
(Bacillus
subtilis) 		4 / 5 ASP A  86
LEU A  85
MET A 114
ARG A 113
 None
 1.28A 2gj5A-1ny1A:
0.0		 2gj5A-1ny1A:
19.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LSL_D_PZID802_0
(GLUTAMATE RECEPTOR 2)		 1ny1 PROBABLE
POLYSACCHARIDE
DEACETYLASE PDAA
(Bacillus
subtilis) 		3 / 3 SER A 115
ASP A 158
ASN A 159
 None
 0.95A 3lslA-1ny1A:
undetectable
3lslD-1ny1A:
undetectable		 3lslA-1ny1A:
22.54
3lslD-1ny1A:
22.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TBG_A_RTZA2_1
(CYTOCHROME P450 2D6)		 1ny1 PROBABLE
POLYSACCHARIDE
DEACETYLASE PDAA
(Bacillus
subtilis) 		5 / 11 LEU A 131
VAL A 173
VAL A 185
THR A 184
PHE A  98
 None
 1.41A 3tbgA-1ny1A:
undetectable		 3tbgA-1ny1A:
18.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V4T_D_ACTD502_0
(UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE)		 1ny1 PROBABLE
POLYSACCHARIDE
DEACETYLASE PDAA
(Bacillus
subtilis) 		3 / 3 GLY A 216
THR A  67
ASN A  62
 None
 0.62A 3v4tD-1ny1A:
0.0		 3v4tD-1ny1A:
20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K0B_B_SAMB504_0
(S-ADENOSYLMETHIONINE
SYNTHASE)		 1ny1 PROBABLE
POLYSACCHARIDE
DEACETYLASE PDAA
(Bacillus
subtilis) 		4 / 8 ASP A 251
ASN A 159
ASP A 158
ILE A 120
 None
 0.94A 4k0bA-1ny1A:
undetectable		 4k0bA-1ny1A:
22.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L7I_B_SAMB501_0
(S-ADENOSYLMETHIONINE
SYNTHASE)		 1ny1 PROBABLE
POLYSACCHARIDE
DEACETYLASE PDAA
(Bacillus
subtilis) 		4 / 8 ASP A 251
ASN A 159
ASP A 158
ILE A 120
 None
 0.95A 4l7iA-1ny1A:
undetectable		 4l7iA-1ny1A:
22.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LG3_I_Z80I401_1
(GAMMA-AMINOBUTYRIC-A
CID RECEPTOR SUBUNIT
BETA-1)		 1ny1 PROBABLE
POLYSACCHARIDE
DEACETYLASE PDAA
(Bacillus
subtilis) 		4 / 9 PHE A  97
VAL A 150
THR A 154
ASP A 116
 None
 0.84A 5lg3I-1ny1A:
undetectable		 5lg3I-1ny1A:
24.05
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5NCD_A_ACTA301_0
(PEPTIDOGLYCAN
N-ACETYLGLUCOSAMINE
DEACETYLASE)		 1ny1 PROBABLE
POLYSACCHARIDE
DEACETYLASE PDAA
(Bacillus
subtilis) 		4 / 6 ASP A  73
HIS A 124
HIS A 128
HIS A 222
 None
 0.66A 5ncdA-1ny1A:
20.9
5ncdD-1ny1A:
21.0		 5ncdA-1ny1A:
30.23
5ncdD-1ny1A:
30.23
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5NCD_C_ACTC301_0
(PEPTIDOGLYCAN
N-ACETYLGLUCOSAMINE
DEACETYLASE)		 1ny1 PROBABLE
POLYSACCHARIDE
DEACETYLASE PDAA
(Bacillus
subtilis) 		4 / 6 ASP A  73
HIS A 124
HIS A 128
HIS A 222
 None
 0.68A 5ncdB-1ny1A:
21.1
5ncdC-1ny1A:
21.1		 5ncdB-1ny1A:
30.23
5ncdC-1ny1A:
30.23
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5NCD_D_ACTD301_0
(PEPTIDOGLYCAN
N-ACETYLGLUCOSAMINE
DEACETYLASE)		 1ny1 PROBABLE
POLYSACCHARIDE
DEACETYLASE PDAA
(Bacillus
subtilis) 		4 / 4 ASP A  73
HIS A 124
HIS A 128
HIS A 222
 None
 0.72A 5ncdD-1ny1A:
21.0		 5ncdD-1ny1A:
30.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NEK_B_AZMB302_1
(PEPTIDOGLYCAN
N-ACETYLGLUCOSAMINE
DEACETYLASE)		 1ny1 PROBABLE
POLYSACCHARIDE
DEACETYLASE PDAA
(Bacillus
subtilis) 		5 / 8 ASP A  73
HIS A 124
HIS A 128
PRO A 165
TRP A 194
 None
 0.81A 5nekB-1ny1A:
21.1		 5nekB-1ny1A:
18.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NEK_B_AZMB302_1
(PEPTIDOGLYCAN
N-ACETYLGLUCOSAMINE
DEACETYLASE)		 1ny1 PROBABLE
POLYSACCHARIDE
DEACETYLASE PDAA
(Bacillus
subtilis) 		5 / 8 ASP A  73
HIS A 124
HIS A 128
TRP A 194
HIS A 222
 None
 0.72A 5nekB-1ny1A:
21.1		 5nekB-1ny1A:
18.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NEK_D_AZMD302_1
(PEPTIDOGLYCAN
N-ACETYLGLUCOSAMINE
DEACETYLASE)		 1ny1 PROBABLE
POLYSACCHARIDE
DEACETYLASE PDAA
(Bacillus
subtilis) 		6 / 8 ASP A  73
HIS A 124
HIS A 128
TRP A 187
TRP A 194
HIS A 222
 None
 0.74A 5nekD-1ny1A:
21.0		 5nekD-1ny1A:
18.97
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5NEL_A_ACTA302_0
(PEPTIDOGLYCAN
N-ACETYLGLUCOSAMINE
DEACETYLASE)		 1ny1 PROBABLE
POLYSACCHARIDE
DEACETYLASE PDAA
(Bacillus
subtilis) 		4 / 6 ASP A  73
HIS A 124
HIS A 128
HIS A 222
 None
 0.59A 5nelA-1ny1A:
21.0
5nelD-1ny1A:
20.9		 5nelA-1ny1A:
30.23
5nelD-1ny1A:
30.23
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5NEL_C_ACTC302_0
(PEPTIDOGLYCAN
N-ACETYLGLUCOSAMINE
DEACETYLASE)		 1ny1 PROBABLE
POLYSACCHARIDE
DEACETYLASE PDAA
(Bacillus
subtilis) 		5 / 6 ASP A  73
HIS A 124
HIS A 128
LEU A 220
HIS A 222
 None
 0.70A 5nelB-1ny1A:
21.2
5nelC-1ny1A:
20.9		 5nelB-1ny1A:
30.23
5nelC-1ny1A:
30.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NFP_A_8W5A804_2
(GLUCOCORTICOID
RECEPTOR)		 1ny1 PROBABLE
POLYSACCHARIDE
DEACETYLASE PDAA
(Bacillus
subtilis) 		4 / 4 LEU A 220
MET A 209
ILE A 249
LEU A  70
 None
 1.33A 5nfpA-1ny1A:
0.0		 5nfpA-1ny1A:
22.26